| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the IC-86621-7518 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHNAK | AHNAK nucleoprotein |
| ALPK1 | alpha-kinase 1 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| BAIAP2 | BAI1-associated protein 2 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CALD1 | caldesmon 1 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CCDC93 | coiled-coil domain containing 93 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDV3 | CDV3 homolog (mouse) |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CEP164 | centrosomal protein 164kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLN5 | ceroid-lipofuscinosis, neuronal 5 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERP44 | endoplasmic reticulum protein 44 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FHL1 | four and a half LIM domains 1 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GDF5 | growth differentiation factor 5 |
| HIST1H4D | histone cluster 1, H4d |
| HSF1 | heat shock transcription factor 1 |
| IL11RA | interleukin 11 receptor, alpha |
| IL1RAP | interleukin 1 receptor accessory protein |
| JAK2 | Janus kinase 2 |
| KHSRP | KH-type splicing regulatory protein |
| KLF12 | Kruppel-like factor 12 |
| LDB1 | LIM domain binding 1 |
| LMNA | lamin A/C |
| LOC81691 | exonuclease NEF-sp |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRRC6 | leucine rich repeat containing 6 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MED18 | mediator complex subunit 18 |
| MED20 | mediator complex subunit 20 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MFN2 | mitofusin 2 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MTCP1 | mature T-cell proliferation 1 |
| NEK1 | NIMA-related kinase 1 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| OSMR | oncostatin M receptor |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PDAP1 | PDGFA associated protein 1 |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHF7 | PHD finger protein 7 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| QKI | QKI, KH domain containing, RNA binding |
| RAB23 | RAB23, member RAS oncogene family |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF39 | ring finger protein 39 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCRN3 | secernin 3 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SKAP1 | src kinase associated phosphoprotein 1 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPIDR | scaffolding protein involved in DNA repair |
| SSH3 | slingshot protein phosphatase 3 |
| STOML1 | stomatin (EPB72)-like 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| STX6 | syntaxin 6 |
| TCTN2 | tectonic family member 2 |
| TFCP2 | transcription factor CP2 |
| TMCO3 | transmembrane and coiled-coil domains 3 |
| TMEM8B | transmembrane protein 8B |
| TRIM2 | tripartite motif containing 2 |
| TSPAN9 | tetraspanin 9 |
| USP6 | ubiquitin specific peptidase 6 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| YIPF5 | Yip1 domain family, member 5 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF318 | zinc finger protein 318 |
| ZNF41 | zinc finger protein 41 |
| ZNF552 | zinc finger protein 552 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACVR2B | activin A receptor, type IIB |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BMP4 | bone morphogenetic protein 4 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CBX8 | chromobox homolog 8 |
| CD5 | CD5 molecule |
| CDIP1 | cell death-inducing p53 target 1 |
| CENPO | centromere protein O |
| CLEC4E | C-type lectin domain family 4, member E |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNTFR | ciliary neurotrophic factor receptor |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYSLTR2 | cysteinyl leukotriene receptor 2 |
| DDN | dendrin |
| DISC1 | disrupted in schizophrenia 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOCK1 | dedicator of cytokinesis 1 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DUSP9 | dual specificity phosphatase 9 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ERF | Ets2 repressor factor |
| FFAR3 | free fatty acid receptor 3 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GOLGA2P5 | golgin A2 pseudogene 5 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HOMER2 | homer scaffolding protein 2 |
| HOXC8 | homeobox C8 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IPO8 | importin 8 |
| IQCC | IQ motif containing C |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KRT86 | keratin 86, type II |
| LHX6 | LIM homeobox 6 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MORN1 | MORN repeat containing 1 |
| MX1 | MX dynamin-like GTPase 1 |
| NOL12 | nucleolar protein 12 |
| ONECUT2 | one cut homeobox 2 |
| PCDHA9 | protocadherin alpha 9 |
| PCDHB13 | protocadherin beta 13 |
| PEG3 | paternally expressed 3 |
| PGP | phosphoglycolate phosphatase |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLA2G15 | phospholipase A2, group XV |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PQLC2 | PQ loop repeat containing 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
| PROSER1 | proline and serine rich 1 |
| PRSS53 | protease, serine, 53 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB36 | RAB36, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RNF170 | ring finger protein 170 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SECISBP2 | SECIS binding protein 2 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPRYD7 | SPRY domain containing 7 |
| SSBP3 | single stranded DNA binding protein 3 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYNGR3 | synaptogyrin 3 |
| TASP1 | taspase, threonine aspartase, 1 |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TNS2 | tensin 2 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTF2 | transcription termination factor, RNA polymerase II |
| TUBA3C | tubulin, alpha 3c |
| URGCP | upregulator of cell proliferation |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF408 | zinc finger protein 408 |
| ZNF446 | zinc finger protein 446 |
| ZNF749 | zinc finger protein 749 |
| ZNF778 | zinc finger protein 778 |
