| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the IC-86621-7543 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ATG3 | autophagy related 3 |
| BBS7 | Bardet-Biedl syndrome 7 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C3 | complement component 3 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDH18 | cadherin 18, type 2 |
| CDK3 | cyclin-dependent kinase 3 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CUL7 | cullin 7 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DMC1 | DNA meiotic recombinase 1 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| EMC1 | ER membrane protein complex subunit 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| FAM134B | family with sequence similarity 134, member B |
| FBXO11 | F-box protein 11 |
| FRK | fyn-related Src family tyrosine kinase |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| GPR153 | G protein-coupled receptor 153 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GSTM1 | glutathione S-transferase mu 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HN1L | hematological and neurological expressed 1-like |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIF5C | kinesin family member 5C |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL28 | kelch-like family member 28 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT17 | keratin 17, type I |
| LMF1 | lipase maturation factor 1 |
| LMO4 | LIM domain only 4 |
| LOC730101 | uncharacterized LOC730101 |
| LPXN | leupaxin |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| METTL3 | methyltransferase like 3 |
| MFAP2 | microfibrillar-associated protein 2 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYO1F | myosin IF |
| PASK | PAS domain containing serine/threonine kinase |
| PGK1 | phosphoglycerate kinase 1 |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PKP3 | plakophilin 3 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTK6 | protein tyrosine kinase 6 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RARG | retinoic acid receptor, gamma |
| RBL2 | retinoblastoma-like 2 |
| RBM19 | RNA binding motif protein 19 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 |
| RPS14 | ribosomal protein S14 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SIX1 | SIX homeobox 1 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SLC25A17 | solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SPATA5L1 | spermatogenesis associated 5-like 1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STC1 | stanniocalcin 1 |
| STX1A | syntaxin 1A (brain) |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TM2D1 | TM2 domain containing 1 |
| TMC7 | transmembrane channel-like 7 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| UBB | ubiquitin B |
| ZFX | zinc finger protein, X-linked |
| ZNF45 | zinc finger protein 45 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACVR2B | activin A receptor, type IIB |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAX | BCL2-associated X protein |
| CALML5 | calmodulin-like 5 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLSPN | claspin |
| CLSTN2 | calsyntenin 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DTWD1 | DTW domain containing 1 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV7 | ets variant 7 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FKRP | fukutin related protein |
| FOXN2 | forkhead box N2 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR182 | G protein-coupled receptor 182 |
| HDAC11 | histone deacetylase 11 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4C | histone cluster 1, H4c |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IFI6 | interferon, alpha-inducible protein 6 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIF16B | kinesin family member 16B |
| KLHL25 | kelch-like family member 25 |
| KLK5 | kallikrein-related peptidase 5 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MITF | microphthalmia-associated transcription factor |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NKRF | NFKB repressing factor |
| NME5 | NME/NM23 family member 5 |
| OTUD3 | OTU deubiquitinase 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARG | poly (ADP-ribose) glycohydrolase |
| PAX9 | paired box 9 |
| PCBP4 | poly(rC) binding protein 4 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PLAC1 | placenta-specific 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLXNB3 | plexin B3 |
| PORCN | porcupine homolog (Drosophila) |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF208 | ring finger protein 208 |
| RNF43 | ring finger protein 43 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SCARA3 | scavenger receptor class A, member 3 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPARCL1 | SPARC-like 1 (hevin) |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STIM1 | stromal interaction molecule 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAOK1 | TAO kinase 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TIGD6 | tigger transposable element derived 6 |
| TMEM183A | transmembrane protein 183A |
| TMEM53 | transmembrane protein 53 |
| TNNI3 | troponin I type 3 (cardiac) |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBA3C | tubulin, alpha 3c |
| UBXN6 | UBX domain protein 6 |
| ULBP2 | UL16 binding protein 2 |
| VGF | VGF nerve growth factor inducible |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF350 | zinc finger protein 350 |
| ZNF358 | zinc finger protein 358 |
| ZNF362 | zinc finger protein 362 |
