ICK Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description intestinal cell (MAK-like) kinase|Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 22858)
External Link http://www.ncbi.nlm.nih.gov/gene/22858
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Genes

93 interacting proteins for ICK from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ADD3 adducin 3 (gamma)
AHNAK AHNAK nucleoprotein
ALG3 ALG3, alpha-1,3- mannosyltransferase
APP amyloid beta (A4) precursor protein
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
BAG6 BCL2-associated athanogene 6
BCLAF1 BCL2-associated transcription factor 1
BUD13 BUD13 homolog (S. cerevisiae)
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CD247 CD247 molecule
CDC37 cell division cycle 37
CDC7 cell division cycle 7
CDK20 cyclin-dependent kinase 20
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTTN cortactin
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DKC1 dyskeratosis congenita 1, dyskerin
DTX3L deltex 3 like, E3 ubiquitin ligase
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EXOSC9 exosome component 9
FIP1L1 factor interacting with PAPOLA and CPSF1
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
HACD3 3-hydroxyacyl-CoA dehydratase 3
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
ILF3 interleukin enhancer binding factor 3, 90kDa
IQSEC1 IQ motif and Sec7 domain 1
JUP junction plakoglobin
KIAA1462 KIAA1462
LAD1 ladinin 1
LARP7 La ribonucleoprotein domain family, member 7
LIMA1 LIM domain and actin binding 1
LMNA lamin A/C
LMNB1 lamin B1
LMNB2 lamin B2
LSR lipolysis stimulated lipoprotein receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
LZTS2 leucine zipper, putative tumor suppressor 2
MAPK1 mitogen-activated protein kinase 1
MARVELD2 MARVEL domain containing 2
MATR3 matrin 3
MCM2 minichromosome maintenance complex component 2
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MNAT1 MNAT CDK-activating kinase assembly factor 1
MYO1C myosin IC
NOP2 NOP2 nucleolar protein
NOP56 NOP56 ribonucleoprotein
NUP188 nucleoporin 188kDa
NUP88 nucleoporin 88kDa
PKP2 plakophilin 2
PKP3 plakophilin 3
PLEC plectin
PPAN peter pan homolog (Drosophila)
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRKCD protein kinase C, delta
PRPF3 pre-mRNA processing factor 3
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
RBM14 RNA binding motif protein 14
RBM39 RNA binding motif protein 39
RGS7 regulator of G-protein signaling 7
RPTOR regulatory associated protein of MTOR, complex 1
RSRC2 arginine/serine-rich coiled-coil 2
SDAD1 SDA1 domain containing 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SMAD1 SMAD family member 1
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SNW1 SNW domain containing 1
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
SUMO1 small ubiquitin-like modifier 1
THRAP3 thyroid hormone receptor associated protein 3
TP53 tumor protein p53
TTC7A tetratricopeptide repeat domain 7A
USP39 ubiquitin specific peptidase 39
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VCP valosin containing protein
WDR43 WD repeat domain 43
XRN2 5'-3' exoribonuclease 2
ZC3H18 zinc finger CCCH-type containing 18
ZNF185 zinc finger protein 185 (LIM domain)