IER3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description immediate early response 3|This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8870)
External Link https://ncbi.nlm.nih.gov/gene/8870
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Genes

499 genes differentially expressed following the IER3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 0.0102412
KYNU kynureninase 0.00973433
S100P S100 calcium binding protein P 0.00952216
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00936687
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00922423
CXCL13 chemokine (C-X-C motif) ligand 13 0.00885251
COG7 component of oligomeric golgi complex 7 0.00867969
PLK2 polo-like kinase 2 0.00852064
BST2 bone marrow stromal cell antigen 2 0.00831536
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00823996
HSPB1 heat shock 27kDa protein 1 0.00823622
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00802198
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00797337
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00793493
XIC X chromosome inactivation center 0.00786047
AGR2 anterior gradient 2 0.00780583
TFF1 trefoil factor 1 0.00780433
SPARCL1 SPARC-like 1 (hevin) 0.00753783
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00747158
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00724943
DMXL2 Dmx-like 2 0.00714102
DENND2D DENN/MADD domain containing 2D 0.00713769
PEG3 paternally expressed 3 0.00699473
C1ORF54 chromosome 1 open reading frame 54 0.00689125
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.0065662
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00648966
MGP matrix Gla protein 0.00648329
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00645171
ANXA6 annexin A6 0.00638281
CXCL14 chemokine (C-X-C motif) ligand 14 0.00633824
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00623692
IL32 interleukin 32 0.00618824
ABLIM1 actin binding LIM protein 1 0.0061833
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00610328
LGMN legumain 0.00609928
POSTN periostin, osteoblast specific factor 0.00605232
HOMER3 homer scaffolding protein 3 0.00603561
PALLD palladin, cytoskeletal associated protein 0.00601785
ABHD6 abhydrolase domain containing 6 0.00596872
CSRP2 cysteine and glycine-rich protein 2 0.00593915
C3ORF14 chromosome 3 open reading frame 14 0.00585784
CAPN3 calpain 3, (p94) 0.00585201
C1S complement component 1, s subcomponent 0.00584526
EXOSC4 exosome component 4 0.00576787
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00570657
PDIA3 protein disulfide isomerase family A, member 3 0.00568322
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00564997
TAGLN transgelin 0.0056009
C8ORF4 chromosome 8 open reading frame 4 0.00556853
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00551236
PLTP phospholipid transfer protein 0.00551112
A2M alpha-2-macroglobulin 0.00549306
MSRB2 methionine sulfoxide reductase B2 0.00545164
TARP TCR gamma alternate reading frame protein 0.00543635
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00540011
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00536592
CD36 CD36 molecule (thrombospondin receptor) 0.00536234
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 0.00529091
ISG20 interferon stimulated exonuclease gene 20kDa 0.0052737
ABHD4 abhydrolase domain containing 4 0.00525543
PBX1 pre-B-cell leukemia homeobox 1 0.00524861
FYB1 FYN binding protein 1 0.0052409
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00524
ACTA1 actin, alpha 1, skeletal muscle 0.00522727
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.00522563
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.00522072
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.00520746
CST3 cystatin C 0.00520478
FXYD3 FXYD domain containing ion transport regulator 3 0.00520019
CES1 carboxylesterase 1 0.00519385
GLIPR1 GLI pathogenesis-related 1 0.00518894
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00516049
WASHC4 WASH complex subunit 4 0.00515882
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00514218
MAP2K6 mitogen-activated protein kinase kinase 6 0.00511216
ISG15 ISG15 ubiquitin-like modifier 0.00509537
TNNC1 troponin C type 1 (slow) 0.00509008
CXCL12 chemokine (C-X-C motif) ligand 12 0.00508765
JAG1 jagged 1 0.00502818
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.00502574
CNTN1 contactin 1 0.00498042
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00496249
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.00495859
MMP9 matrix metallopeptidase 9 0.00495304
CCL5 chemokine (C-C motif) ligand 5 0.00494794
NCK1 NCK adaptor protein 1 0.00494655
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00493813
HOXA5 homeobox A5 0.00489943
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00489182
CCL19 chemokine (C-C motif) ligand 19 0.00488272
COPS7A COP9 signalosome subunit 7A 0.00487082
CPE carboxypeptidase E 0.00485974
TESC tescalcin 0.00485853
KDM3A lysine (K)-specific demethylase 3A 0.00485709
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00483615
TSPAN1 tetraspanin 1 0.00480284
RNASET2 ribonuclease T2 0.00479924
GPNMB glycoprotein (transmembrane) nmb 0.00475235
AHNAK AHNAK nucleoprotein 0.00473669
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.00472738
GUCY2C guanylate cyclase 2C 0.00471954
ZYX zyxin 0.00471724
MYO1C myosin IC 0.00469571
FBN2 fibrillin 2 0.00469132
CA12 carbonic anhydrase XII 0.00468281
CTSE cathepsin E 0.00466982
LOXL2 lysyl oxidase-like 2 0.0046513
PNMA2 paraneoplastic Ma antigen 2 0.00462217
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00461375
PARM1 prostate androgen-regulated mucin-like protein 1 0.00461193
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.00460946
CCL20 chemokine (C-C motif) ligand 20 0.00458062
TRIM16 tripartite motif containing 16 0.00456912
CHGB chromogranin B 0.00454938
SPRED2 sprouty-related, EVH1 domain containing 2 0.00452407
SNAP25 synaptosomal-associated protein, 25kDa 0.00452167
ACOX2 acyl-CoA oxidase 2, branched chain 0.00449181
NPDC1 neural proliferation, differentiation and control, 1 0.00448488
MYBPC1 myosin binding protein C, slow type 0.0044781
GOLGA8H golgin A8 family, member H 0.0044739
TMEM176A transmembrane protein 176A 0.00447376
TGFA transforming growth factor, alpha 0.00446384
TP53 tumor protein p53 0.00445562
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.00444242
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00443902
PLN phospholamban 0.00443047
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.00442712
NEBL nebulette 0.00442323
BHLHE41 basic helix-loop-helix family, member e41 0.00440427
FN1 fibronectin 1 0.00439181
AKAP12 A kinase (PRKA) anchor protein 12 0.0043845
CD27 CD27 molecule 0.00438322
FABP7 fatty acid binding protein 7, brain 0.00438015
METRN meteorin, glial cell differentiation regulator 0.00437718
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.004354
GPX1 glutathione peroxidase 1 0.00435068
LGALS1 lectin, galactoside-binding, soluble, 1 0.0043377
GOLGA8A golgin A8 family, member A 0.00432879
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.00432869
KRT6A keratin 6A, type II 0.00432383
FXYD6 FXYD domain containing ion transport regulator 6 0.00432065
TRIM14 tripartite motif containing 14 0.00431212
ASPN asporin 0.00430944
RGS5 regulator of G-protein signaling 5 0.00430832
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00429486
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00428884
EDN3 endothelin 3 0.00428278
NPC2 Niemann-Pick disease, type C2 0.00428117
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00427353
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00427178
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.00426976
TIGAR TP53 induced glycolysis regulatory phosphatase 0.00426162
IFI44L interferon-induced protein 44-like 0.00422637
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00420932
TRIP6 thyroid hormone receptor interactor 6 0.00419862
ADGRE1 adhesion G protein-coupled receptor E1 0.00419857
BAX BCL2-associated X protein 0.00419585
CAST calpastatin 0.00417683
ANXA10 annexin A10 0.00417095
CST1 cystatin SN 0.00416891
ITGAV integrin, alpha V 0.00416837
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00413738
ASPH aspartate beta-hydroxylase 0.00413487
FXR1 fragile X mental retardation, autosomal homolog 1 0.00413459
KRT18 keratin 18, type I 0.00413374
CFD complement factor D (adipsin) 0.0041329
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.00413281
AMIGO2 adhesion molecule with Ig-like domain 2 0.00412901
NRCAM neuronal cell adhesion molecule 0.00411017
REG1A regenerating islet-derived 1 alpha 0.00410761
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00410494
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00409859
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 0.00409731
SOBP sine oculis binding protein homolog (Drosophila) 0.00408702
TAGLN2 transgelin 2 0.00407481
DLD dihydrolipoamide dehydrogenase 0.00406873
RSL1D1 ribosomal L1 domain containing 1 0.00406845
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.0040629
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.00405145
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00403224
CLU clusterin 0.00402458
CTSG cathepsin G 0.00400281
GNAS GNAS complex locus 0.00399477
SP110 SP110 nuclear body protein 0.00398459
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00397746
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00396378
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.00395736
TPM4 tropomyosin 4 0.00394583
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.00394164
OPN3 opsin 3 0.00393341
CD8A CD8a molecule 0.00393181
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.00392535
ACP5 acid phosphatase 5, tartrate resistant 0.00391746
FAM174B family with sequence similarity 174, member B 0.00391613
PYCARD PYD and CARD domain containing 0.00389822
LAMA3 laminin, alpha 3 0.00389768
BAMBI BMP and activin membrane-bound inhibitor 0.00389652
S100A10 S100 calcium binding protein A10 0.00387795
IFIH1 interferon induced with helicase C domain 1 0.00387292
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.00385772
FOS FBJ murine osteosarcoma viral oncogene homolog 0.00385432
FAS Fas cell surface death receptor 0.00384938
THBS2 thrombospondin 2 0.00384263
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.00384229
RPS27L ribosomal protein S27-like 0.00383625
ECM1 extracellular matrix protein 1 0.00383522
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00382843
MEIS1 Meis homeobox 1 0.00382683
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.00382681
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00382271
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.00381352
PEG10 paternally expressed 10 0.00380121
THBD thrombomodulin 0.00379785
ZC2HC1A zinc finger, C2HC-type containing 1A 0.00378893
TLR4 toll-like receptor 4 0.00378053
ANXA1 annexin A1 0.003779
TCTN1 tectonic family member 1 0.00377117
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.00376576
FBLN5 fibulin 5 0.00376552
CDK14 cyclin-dependent kinase 14 0.0037637
LIMA1 LIM domain and actin binding 1 0.0037634
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00375154
HNMT histamine N-methyltransferase 0.00374937
MVP major vault protein 0.0037489
FNDC3B fibronectin type III domain containing 3B 0.00374721
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.00374421
PON2 paraoxonase 2 0.00373558
SH3BGR SH3 domain binding glutamate-rich protein 0.00373361
UBA7 ubiquitin-like modifier activating enzyme 7 0.00372262
RCAN1 regulator of calcineurin 1 0.00371096
DNASE1L3 deoxyribonuclease I-like 3 0.00370944
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00370436
THBS4 thrombospondin 4 0.00370352
NOTCH3 notch 3 0.00370189
CA11 carbonic anhydrase XI 0.00370082
HYOU1 hypoxia up-regulated 1 0.00369101
MRPL19 mitochondrial ribosomal protein L19 0.00367622
NDFIP1 Nedd4 family interacting protein 1 0.00367184
RBKS ribokinase 0.00366605
TICAM1 toll-like receptor adaptor molecule 1 0.00366507
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 0.00366258
ADAM28 ADAM metallopeptidase domain 28 0.00366083
LY75 lymphocyte antigen 75 0.00366002
LDB2 LIM domain binding 2 0.00365792
MX2 MX dynamin-like GTPase 2 0.00365631
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.00364741
OLFML2A olfactomedin-like 2A 0.00364648
CD3D CD3d molecule, delta (CD3-TCR complex) 0.00364571
TIMP1 TIMP metallopeptidase inhibitor 1 0.00364274
S100A14 S100 calcium binding protein A14 0.003642

decreased expression

Symbol Name Standardized Value
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00902283
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00796155
TMSB15A thymosin beta 15a -0.00778121
HBB hemoglobin, beta -0.00758118
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00752705
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00737312
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0073368
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00712898
XPO7 exportin 7 -0.00699702
SRGN serglycin -0.00656092
DSP desmoplakin -0.00651247
KDM5D lysine (K)-specific demethylase 5D -0.00639418
KANK1 KN motif and ankyrin repeat domains 1 -0.00637657
ZW10 zw10 kinetochore protein -0.00636508
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00635344
SCGB1D2 secretoglobin, family 1D, member 2 -0.00635101
JUP junction plakoglobin -0.00631722
AUTS2 autism susceptibility candidate 2 -0.00621229
NT5E 5'-nucleotidase, ecto (CD73) -0.00606442
HBD hemoglobin, delta -0.00596091
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00587659
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00580793
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.00578356
NDNF neuron-derived neurotrophic factor -0.00572471
TGFBR3 transforming growth factor, beta receptor III -0.00571905
COL11A1 collagen, type XI, alpha 1 -0.00568693
LEPR leptin receptor -0.00559103
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00556464
WT1 Wilms tumor 1 -0.005511
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -0.00546537
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00533538
SSBP2 single-stranded DNA binding protein 2 -0.00529252
CBS cystathionine-beta-synthase -0.00526863
WWC3 WWC family member 3 -0.00524239
TAL1 T-cell acute lymphocytic leukemia 1 -0.00518037
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.00499474
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00495631
AQP1 aquaporin 1 (Colton blood group) -0.0049482
NDC80 NDC80 kinetochore complex component -0.0048996
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00486089
SLC38A1 solute carrier family 38, member 1 -0.00484553
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00482976
TPSAB1 tryptase alpha/beta 1 -0.00481911
ADIRF adipogenesis regulatory factor -0.00480019
CCDC92 coiled-coil domain containing 92 -0.00476816
HOXD1 homeobox D1 -0.00473443
S100A8 S100 calcium binding protein A8 -0.00470134
GLDC glycine dehydrogenase (decarboxylating) -0.00470013
IL33R interleukin 33 receptor -0.00468184
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00467697
HOPX HOP homeobox -0.00467085
XK X-linked Kx blood group -0.00463584
NMU neuromedin U -0.004553
SHROOM2 shroom family member 2 -0.00453586
ELOVL5 ELOVL fatty acid elongase 5 -0.00451432
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -0.00450017
ZNF395 zinc finger protein 395 -0.00446665
CLGN calmegin -0.00445004
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00444662
PMP22 peripheral myelin protein 22 -0.00443948
H2AX H2A.X variant histone -0.0044197
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00441669
DPYSL3 dihydropyrimidinase-like 3 -0.0044071
KIF13B kinesin family member 13B -0.00438579
ZNF329 zinc finger protein 329 -0.00436863
KPNA6 karyopherin alpha 6 (importin alpha 7) -0.00436745
ST18 suppression of tumorigenicity 18, zinc finger -0.0043604
SLC43A3 solute carrier family 43, member 3 -0.00434547
VSIG4 V-set and immunoglobulin domain containing 4 -0.0043399
GATA2 GATA binding protein 2 -0.00433584
IGFBP1 insulin-like growth factor binding protein 1 -0.00432986
DCN decorin -0.00432686
OSBPL3 oxysterol binding protein-like 3 -0.00432533
LAPTM5 lysosomal protein transmembrane 5 -0.00432334
CLEC2B C-type lectin domain family 2, member B -0.00431506
GRB7 growth factor receptor-bound protein 7 -0.00430651
DUSP2 dual specificity phosphatase 2 -0.00429684
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00426789
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00425427
KRT15 keratin 15, type I -0.00423869
PXDN peroxidasin -0.00421171
MT1M metallothionein 1M -0.00420578
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00420495
KIF14 kinesin family member 14 -0.00417879
CALCA calcitonin-related polypeptide alpha -0.00417853
C11ORF24 chromosome 11 open reading frame 24 -0.00416872
SFTPB surfactant protein B -0.00415787
SOX9 SRY (sex determining region Y)-box 9 -0.00415676
AREG amphiregulin -0.00413782
CTNND1 catenin (cadherin-associated protein), delta 1 -0.00412761
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00412453
ANPEP alanyl (membrane) aminopeptidase -0.00412419
STK38 serine/threonine kinase 38 -0.00409907
CDC7 cell division cycle 7 -0.00408822
DDAH2 dimethylarginine dimethylaminohydrolase 2 -0.00407074
GPSM2 G-protein signaling modulator 2 -0.00405942
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00404964
STC2 stanniocalcin 2 -0.00403729
TRIM58 tripartite motif containing 58 -0.00403302
GLO1 glyoxalase I -0.00401949
RGCC regulator of cell cycle -0.00400487
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -0.00399647
SLIT2 slit homolog 2 (Drosophila) -0.00398788
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.00396898
MAMLD1 mastermind-like domain containing 1 -0.00396712
LRRC15 leucine rich repeat containing 15 -0.00394455
GMPR guanosine monophosphate reductase -0.00393965
LRRC8B leucine rich repeat containing 8 family, member B -0.00391215
HMGB3 high mobility group box 3 -0.00389855
MALL mal, T-cell differentiation protein-like -0.00387577
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00387524
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -0.00386826
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00386336
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00383645
HMGA1 high mobility group AT-hook 1 -0.00382951
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -0.00382245
LPIN2 lipin 2 -0.0038189
LPPR1 lipid phosphate phosphatase-related protein type 1 -0.00380897
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00376947
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.00376392
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.00374574
PHACTR2 phosphatase and actin regulator 2 -0.0037406
ZNF587 zinc finger protein 587 -0.00373221
DYNLT1 dynein, light chain, Tctex-type 1 -0.00373025
ZEB1 zinc finger E-box binding homeobox 1 -0.00372892
NPM3 nucleophosmin/nucleoplasmin 3 -0.00371596
USP9Y ubiquitin specific peptidase 9, Y-linked -0.0036729
MMRN1 multimerin 1 -0.00367134
PRKD3 protein kinase D3 -0.00366546
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.00365798
LEF1 lymphoid enhancer-binding factor 1 -0.00365598
NID2 nidogen 2 (osteonidogen) -0.00364944
DCTN3 dynactin 3 (p22) -0.00363817
AEBP1 AE binding protein 1 -0.00363806
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00363701
ZSCAN18 zinc finger and SCAN domain containing 18 -0.00363154
AGO2 argonaute RISC catalytic component 2 -0.00362309
HEBP2 heme binding protein 2 -0.0036065
MPRIP myosin phosphatase Rho interacting protein -0.00360206
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00358679
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00358576
TUBB4B tubulin, beta 4B class IVb -0.00358303
ZNF423 zinc finger protein 423 -0.0035742
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.00356883
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00356682
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.0035611
GJA1 gap junction protein, alpha 1, 43kDa -0.00355786
PPL periplakin -0.00355422
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase -0.00355286
ALAS2 5'-aminolevulinate synthase 2 -0.00355185
SFTPC surfactant protein C -0.0035472
SGK1 serum/glucocorticoid regulated kinase 1 -0.00353648
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.00353598
HELLS helicase, lymphoid-specific -0.00353289
UGT8 UDP glycosyltransferase 8 -0.00353152
E2F3 E2F transcription factor 3 -0.00352892
CLIP3 CAP-GLY domain containing linker protein 3 -0.00352588
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00352489
LOX lysyl oxidase -0.00352066
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.00351966
HSPA1A heat shock 70kDa protein 1A -0.00351367
CRP C-reactive protein, pentraxin-related -0.00350412
ALOX5 arachidonate 5-lipoxygenase -0.00350316
NCOA6 nuclear receptor coactivator 6 -0.00349566
SPON2 spondin 2, extracellular matrix protein -0.003486
ADGRG6 adhesion G protein-coupled receptor G6 -0.00347703
RUNX1 runt-related transcription factor 1 -0.00347563
FANCG Fanconi anemia, complementation group G -0.00347048
RAI2 retinoic acid induced 2 -0.00346291
EHF ets homologous factor -0.0034625
CCNF cyclin F -0.00344807
SUMO3 small ubiquitin-like modifier 3 -0.0034446
HAPLN1 hyaluronan and proteoglycan link protein 1 -0.00343595
CIT citron rho-interacting serine/threonine kinase -0.00343259
TSPAN4 tetraspanin 4 -0.00343048
TENT4A terminal nucleotidyltransferase 4A -0.00342591
C4BPA complement component 4 binding protein, alpha -0.0034155
OSBPL10 oxysterol binding protein-like 10 -0.00341437
SCGB2A2 secretoglobin, family 2A, member 2 -0.00341121
HBBP1 hemoglobin, beta pseudogene 1 -0.00341111
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.00340176
EGR3 early growth response 3 -0.00339955
ZNF586 zinc finger protein 586 -0.00339869
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00339258
CD320 CD320 molecule -0.00339209
SCRG1 stimulator of chondrogenesis 1 -0.00338766
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.00338659
KIF18B kinesin family member 18B -0.00338256
ZNF274 zinc finger protein 274 -0.00337723
ODC1 ornithine decarboxylase 1 -0.00335976
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -0.00334885
SV2C synaptic vesicle glycoprotein 2C -0.00334119
APIP APAF1 interacting protein -0.00332168
ZBTB18 zinc finger and BTB domain containing 18 -0.00331989
PRDX2 peroxiredoxin 2 -0.00331894
UBAP2L ubiquitin associated protein 2-like -0.00331389
KIAA1644 KIAA1644 -0.00330373
TSPYL5 TSPY-like 5 -0.00330331
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00330185
ZNF544 zinc finger protein 544 -0.00329832
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -0.00329491
MTMR1 myotubularin related protein 1 -0.00327982
TCTA T-cell leukemia translocation altered -0.00327794
KLK5 kallikrein-related peptidase 5 -0.00327597
RANBP6 RAN binding protein 6 -0.00327327
PFKL phosphofructokinase, liver -0.0032683
KLK7 kallikrein-related peptidase 7 -0.00326341
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 -0.00326173
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00326064
CD47 CD47 molecule -0.00325528
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00325506
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00324836
NXN nucleoredoxin -0.00324294
SLC38A2 solute carrier family 38, member 2 -0.00324122
SRP9 signal recognition particle 9kDa -0.00324076
EZR ezrin -0.00324011
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -0.0032394
PLA2G12A phospholipase A2, group XIIA -0.00323836
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -0.00323285
RBM38 RNA binding motif protein 38 -0.00323277
GAL galanin/GMAP prepropeptide -0.00323223
FAF2 Fas associated factor family member 2 -0.0032287
ARG2 arginase 2 -0.00322289
BAG6 BCL2-associated athanogene 6 -0.00321267
HDC histidine decarboxylase -0.00319545
MCM3 minichromosome maintenance complex component 3 -0.00318947
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00318394
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.0031808
MAP1A microtubule-associated protein 1A -0.00317985
GSTM3 glutathione S-transferase mu 3 (brain) -0.00317456
FZD5 frizzled class receptor 5 -0.00317451
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -0.00316831
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00316771
HOXB2 homeobox B2 -0.00316621
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 -0.00316487
HRASLS HRAS-like suppressor -0.00316385
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding) -0.00315917
PTPRE protein tyrosine phosphatase, receptor type, E -0.00315736
MED20 mediator complex subunit 20 -0.00315582
FBLN1 fibulin 1 -0.00315494
CSNK2B casein kinase 2, beta polypeptide -0.00314911
VPREB1 pre-B lymphocyte 1 -0.00314698
CELF1 CUGBP, Elav-like family member 1 -0.00313806
C5ORF28 chromosome 5 open reading frame 28 -0.00313676
FGFR2 fibroblast growth factor receptor 2 -0.00313412
MFAP5 microfibrillar associated protein 5 -0.00312123
NLGN4X neuroligin 4, X-linked -0.00311863
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -0.00311679
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.00310665