| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | interferon induced with helicase C domain 1|DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012] (NCBI Entrez Gene Database, 64135) |
| External Link | https://ncbi.nlm.nih.gov/gene/64135 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the IFIH1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.0222736 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0218888 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0163504 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0153422 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0145644 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0134101 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0125472 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0123497 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.0121417 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0118292 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0116326 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.011514 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0113028 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.0110327 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0106792 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0102513 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00998194 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00991075 |
| CD81 | CD81 molecule | 0.00984936 |
| KRT18 | keratin 18, type I | 0.0098376 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00941418 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0093331 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00931778 |
| FASN | fatty acid synthase | 0.00894747 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00891625 |
| LOXL1 | lysyl oxidase-like 1 | 0.00890723 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00890282 |
| RUNX3 | runt-related transcription factor 3 | 0.00890112 |
| NOTCH2NL | notch 2 N-terminal like | 0.00884516 |
| TXLNA | taxilin alpha | 0.00883279 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00871403 |
| TGM2 | transglutaminase 2 | 0.00871326 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00861187 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00845592 |
| CST7 | cystatin F (leukocystatin) | 0.00844666 |
| TSPAN4 | tetraspanin 4 | 0.00828941 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.0082518 |
| FBN2 | fibrillin 2 | 0.00820452 |
| MFAP2 | microfibrillar-associated protein 2 | 0.00815872 |
| TCTA | T-cell leukemia translocation altered | 0.00809529 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00801868 |
| XCL1 | chemokine (C motif) ligand 1 | 0.00799013 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00784401 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00782746 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.0078248 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00781664 |
| FZD2 | frizzled class receptor 2 | 0.00776565 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 0.00769827 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00765169 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00764379 |
| RNF19B | ring finger protein 19B | 0.00761436 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00757792 |
| LAMA5 | laminin, alpha 5 | 0.00755819 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00752117 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00751213 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00750316 |
| AUTS2 | autism susceptibility candidate 2 | 0.00749255 |
| SFTPC | surfactant protein C | 0.00744578 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00744073 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00742145 |
| AGRN | agrin | 0.00740841 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00732459 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.00730596 |
| CHKB | choline kinase beta | 0.00730454 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00728922 |
| SPATA20 | spermatogenesis associated 20 | 0.00725527 |
| SFTPA2 | surfactant protein A2 | 0.00724917 |
| SFN | stratifin | 0.00724487 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | 0.00723366 |
| HOPX | HOP homeobox | 0.0072335 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00721839 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00720068 |
| SFTPB | surfactant protein B | 0.00718272 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00717203 |
| SMAD7 | SMAD family member 7 | 0.00716355 |
| TBX3 | T-box 3 | 0.00713607 |
| MYO1D | myosin ID | 0.00710771 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00706387 |
| SEPTIN10 | septin 10 | 0.00703225 |
| TYMP | thymidine phosphorylase | 0.00696783 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00692388 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00691317 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00689744 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00688161 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00687121 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.00685891 |
| DMPK | dystrophia myotonica-protein kinase | 0.00684192 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.006813 |
| NKG7 | natural killer cell granule protein 7 | 0.00680768 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00680722 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.00678707 |
| DST | dystonin | 0.00675882 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00673079 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | 0.00671022 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.0066506 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00663739 |
| DUS1L | dihydrouridine synthase 1-like (S. cerevisiae) | 0.00658386 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.0065829 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00658066 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00657929 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00656832 |
| CD151 | CD151 molecule (Raph blood group) | 0.0065629 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00654979 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | 0.00653144 |
| YBX3 | Y box binding protein 3 | 0.00652805 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00652691 |
| EVA1B | eva-1 homolog B (C. elegans) | 0.00652469 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00651226 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00650119 |
| KRT7 | keratin 7, type II | 0.00647287 |
| C11ORF24 | chromosome 11 open reading frame 24 | 0.00645836 |
| CTSH | cathepsin H | 0.00636262 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | 0.00635602 |
| IRF7 | interferon regulatory factor 7 | 0.00634752 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | 0.00633747 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00631862 |
| ODC1 | ornithine decarboxylase 1 | 0.00630332 |
| PLXND1 | plexin D1 | 0.00630066 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00629752 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.00627611 |
| GPC4 | glypican 4 | 0.00627111 |
| PAEP | progestagen-associated endometrial protein | 0.0062641 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | 0.00626373 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.00625582 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | 0.00624081 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00621822 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00619826 |
| LAMB2 | laminin, beta 2 (laminin S) | 0.00619601 |
| KLC1 | kinesin light chain 1 | 0.00618157 |
| CDC34 | cell division cycle 34 | 0.00616273 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 0.00614538 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00614389 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | 0.00614069 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00612443 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.00612224 |
| RBPMS | RNA binding protein with multiple splicing | 0.00611939 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00611431 |
| HMGB3 | high mobility group box 3 | 0.00610516 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00610177 |
| MYLIP | myosin regulatory light chain interacting protein | 0.00609851 |
| MITF | microphthalmia-associated transcription factor | 0.00608105 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00607765 |
| DUSP2 | dual specificity phosphatase 2 | 0.0060726 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.00605938 |
| PMP22 | peripheral myelin protein 22 | 0.00605841 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.00603877 |
| NVL | nuclear VCP-like | 0.00602501 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.0060119 |
| LGSN | lengsin, lens protein with glutamine synthetase domain | 0.00601021 |
| TUFT1 | tuftelin 1 | 0.00600477 |
| CCNL2 | cyclin L2 | 0.00599756 |
| PLA1A | phospholipase A1 member A | 0.00597715 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 0.00596245 |
| SDC3 | syndecan 3 | 0.00595875 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.00595463 |
| TNK2 | tyrosine kinase, non-receptor, 2 | 0.00595137 |
| MICALL1 | MICAL-like 1 | 0.00592439 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.00592055 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.00589701 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00588836 |
| EXOC3 | exocyst complex component 3 | 0.0058851 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.00586491 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.00586235 |
| EPHB2 | EPH receptor B2 | 0.00585297 |
| ZNF394 | zinc finger protein 394 | 0.00585242 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | 0.00584404 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0058373 |
| CPM | carboxypeptidase M | 0.00583428 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 0.00582428 |
| FSTL1 | follistatin-like 1 | 0.00581202 |
| NUCB1 | nucleobindin 1 | 0.00580225 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00580214 |
| SFTPD | surfactant protein D | 0.00580064 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00579627 |
| SIK1 | salt-inducible kinase 1 | 0.00578521 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00578505 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.00577028 |
| UCKL1 | uridine-cytidine kinase 1-like 1 | 0.00574004 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00573164 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00572111 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00572038 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00570866 |
| KIF5B | kinesin family member 5B | 0.0056902 |
| GOLGA8H | golgin A8 family, member H | 0.0056844 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00565947 |
| MAGED1 | melanoma antigen family D1 | 0.00565541 |
| CHMP2A | charged multivesicular body protein 2A | 0.0056519 |
| TLK2 | tousled-like kinase 2 | 0.00564233 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.00563756 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00563314 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00562813 |
| RGS1 | regulator of G-protein signaling 1 | 0.00562713 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | 0.00562701 |
| DROSHA | drosha, ribonuclease type III | 0.00561335 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00560762 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 0.00560396 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00560196 |
| HMG20B | high mobility group 20B | 0.00559429 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00558912 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00558773 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00558152 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.0055768 |
| NOP53 | NOP53 ribosome biogenesis factor | 0.0055581 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00554388 |
| STXBP2 | syntaxin binding protein 2 | 0.00553083 |
| TBCD | tubulin folding cofactor D | 0.0055238 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00552372 |
| TRAF5 | TNF receptor-associated factor 5 | 0.00552114 |
| ZNF146 | zinc finger protein 146 | 0.00551929 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.00551719 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0055037 |
| RABAC1 | Rab acceptor 1 (prenylated) | 0.0054964 |
| CTSA | cathepsin A | 0.00549154 |
| DVL1 | dishevelled segment polarity protein 1 | 0.00548688 |
| ACACA | acetyl-CoA carboxylase alpha | 0.00548483 |
| RAB38 | RAB38, member RAS oncogene family | 0.00547875 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00547351 |
| CAPNS1 | calpain, small subunit 1 | 0.00546981 |
| FAM193A | family with sequence similarity 193, member A | 0.00546902 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | 0.00546471 |
| BIN1 | bridging integrator 1 | 0.00546161 |
| RUBCN | rubicon autophagy regulator | 0.00545521 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00545465 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.00544133 |
| PMF1 | polyamine-modulated factor 1 | 0.00543994 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00543086 |
| INTS1 | integrator complex subunit 1 | 0.00542678 |
| SYNGR2 | synaptogyrin 2 | 0.00541802 |
| TLE2 | transducin-like enhancer of split 2 | 0.00541006 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00540793 |
| JMJD1C | jumonji domain containing 1C | 0.00540667 |
| TOX3 | TOX high mobility group box family member 3 | 0.00540344 |
| ATP11B | ATPase, class VI, type 11B | 0.0053914 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00538848 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.00538163 |
| RTN2 | reticulon 2 | 0.00538032 |
| PXN | paxillin | 0.00537412 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.00537406 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00536944 |
| SMTN | smoothelin | 0.00536125 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 | 0.00535939 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0053584 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00535746 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00535091 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00534265 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00534068 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0053361 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00533315 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP4 | bone morphogenetic protein 4 | -0.0200335 |
| S100A8 | S100 calcium binding protein A8 | -0.0171797 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0133133 |
| MT1H | metallothionein 1H | -0.0126968 |
| MAL | mal, T-cell differentiation protein | -0.0126596 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.012614 |
| AK4 | adenylate kinase 4 | -0.0122673 |
| LCN2 | lipocalin 2 | -0.012122 |
| MT1X | metallothionein 1X | -0.0120194 |
| WDR7 | WD repeat domain 7 | -0.0118734 |
| S100A9 | S100 calcium binding protein A9 | -0.0118523 |
| MT1HL1 | metallothionein 1H-like 1 | -0.0117988 |
| PEG3 | paternally expressed 3 | -0.011444 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.011164 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0111239 |
| PROM1 | prominin 1 | -0.0110023 |
| MT1G | metallothionein 1G | -0.0105801 |
| XIC | X chromosome inactivation center | -0.010473 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0104516 |
| RGS4 | regulator of G-protein signaling 4 | -0.0103933 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0103858 |
| PLPBP | pyridoxal phosphate binding protein | -0.0103336 |
| MT1F | metallothionein 1F | -0.0101089 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.010106 |
| SELL | selectin L | -0.010105 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.010031 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0100057 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00996441 |
| MT1E | metallothionein 1E | -0.00984088 |
| LXN | latexin | -0.00980429 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00973662 |
| CFI | complement factor I | -0.00971077 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00950429 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00934156 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00928542 |
| TEX10 | testis expressed 10 | -0.00923635 |
| PADI2 | peptidyl arginine deiminase, type II | -0.0091373 |
| MT2A | metallothionein 2A | -0.00910324 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00910063 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00905114 |
| CD200 | CD200 molecule | -0.00903271 |
| TSPAN7 | tetraspanin 7 | -0.00891895 |
| PITX3 | paired-like homeodomain 3 | -0.00888475 |
| KRT15 | keratin 15, type I | -0.00888028 |
| LTF | lactotransferrin | -0.00886428 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00886295 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00885873 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00877137 |
| ATP10B | ATPase, class V, type 10B | -0.00874206 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00871461 |
| METTL7A | methyltransferase like 7A | -0.00866657 |
| KLK10 | kallikrein-related peptidase 10 | -0.00864653 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00854797 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.00851825 |
| S100A7 | S100 calcium binding protein A7 | -0.00846694 |
| ADD3 | adducin 3 (gamma) | -0.00846637 |
| PLK1 | polo-like kinase 1 | -0.00846598 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0084612 |
| PALMD | palmdelphin | -0.00845632 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00841537 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0084097 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0082437 |
| DOK5 | docking protein 5 | -0.0082371 |
| ANXA1 | annexin A1 | -0.00820446 |
| CRYAB | crystallin, alpha B | -0.00817971 |
| AZIN1 | antizyme inhibitor 1 | -0.0081253 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.0080993 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.0080657 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00804885 |
| KRT23 | keratin 23, type I | -0.00792469 |
| C7 | complement component 7 | -0.00790051 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | -0.00789873 |
| SGCE | sarcoglycan, epsilon | -0.00789606 |
| GOLT1B | golgi transport 1B | -0.00780082 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00771772 |
| MAT2B | methionine adenosyltransferase II, beta | -0.00770648 |
| CHRDL1 | chordin-like 1 | -0.00770365 |
| EVI2A | ecotropic viral integration site 2A | -0.00768639 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | -0.00764705 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.00764151 |
| AOX1 | aldehyde oxidase 1 | -0.00761278 |
| ADM | adrenomedullin | -0.00761228 |
| CALB1 | calbindin 1, 28kDa | -0.00759822 |
| MGP | matrix Gla protein | -0.00759359 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00753806 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00750015 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00748048 |
| MT1M | metallothionein 1M | -0.00746613 |
| IL1RN | interleukin 1 receptor antagonist | -0.00744268 |
| G0S2 | G0/G1 switch 2 | -0.00743939 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00737195 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00735813 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00735548 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | -0.00731373 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | -0.00731242 |
| CYRIA | CYFIP related Rac1 interactor A | -0.00729513 |
| HTRA1 | HtrA serine peptidase 1 | -0.00729139 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00728974 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.00728183 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00725903 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00722716 |
| CP | ceruloplasmin (ferroxidase) | -0.00721815 |
| PAH | phenylalanine hydroxylase | -0.00721347 |
| ERP44 | endoplasmic reticulum protein 44 | -0.00720832 |
| MMP12 | matrix metallopeptidase 12 | -0.00720599 |
| CLDN10 | claudin 10 | -0.00720043 |
| GAP43 | growth associated protein 43 | -0.00719535 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00719056 |
| PLP1 | proteolipid protein 1 | -0.00716252 |
| CAST | calpastatin | -0.0071505 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.00713923 |
| CLDN8 | claudin 8 | -0.00709244 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00708557 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | -0.0070645 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.0070377 |
| MSH2 | mutS homolog 2 | -0.00701414 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00695879 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00695871 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00695857 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00692864 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00689436 |
| THBS2 | thrombospondin 2 | -0.00686096 |
| CCN2 | cellular communication network factor 2 | -0.00679727 |
| GUCY2C | guanylate cyclase 2C | -0.00678504 |
| TXNL1 | thioredoxin-like 1 | -0.00677496 |
| FZD6 | frizzled class receptor 6 | -0.00677278 |
| GRAMD1C | GRAM domain containing 1C | -0.00677039 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00672822 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00672625 |
| GLUL | glutamate-ammonia ligase | -0.00671976 |
| PLIN1 | perilipin 1 | -0.00668219 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0066495 |
| EFNB3 | ephrin-B3 | -0.00664945 |
| FKBP5 | FK506 binding protein 5 | -0.00663815 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00660024 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00659241 |
| CCK | cholecystokinin | -0.00659027 |
| ALB | albumin | -0.00658229 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00657666 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00657451 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00655926 |
| DNTT | DNA nucleotidylexotransferase | -0.00654351 |
| LY75 | lymphocyte antigen 75 | -0.0065423 |
| FCGBP | Fc fragment of IgG binding protein | -0.00652234 |
| CANX | calnexin | -0.0065109 |
| NEK2 | NIMA-related kinase 2 | -0.00648651 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00647661 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00647626 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.00646469 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00643709 |
| EGR3 | early growth response 3 | -0.0064234 |
| LOX | lysyl oxidase | -0.0064095 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00637288 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00635761 |
| FHIT | fragile histidine triad | -0.00632494 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00632379 |
| EXOC5 | exocyst complex component 5 | -0.00631094 |
| TMEM100 | transmembrane protein 100 | -0.00630053 |
| KLK8 | kallikrein-related peptidase 8 | -0.00628599 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.0062836 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase | -0.00626151 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00625998 |
| KRCC1 | lysine-rich coiled-coil 1 | -0.00625355 |
| TAGLN3 | transgelin 3 | -0.00623814 |
| CTSS | cathepsin S | -0.00621448 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00621364 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00616465 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00615783 |
| MMD | monocyte to macrophage differentiation-associated | -0.00612831 |
| CDO1 | cysteine dioxygenase type 1 | -0.00612489 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00612412 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0061238 |
| KRT19 | keratin 19, type I | -0.00612374 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | -0.00611648 |
| IER3IP1 | immediate early response 3 interacting protein 1 | -0.00610669 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00609934 |
| CHEK1 | checkpoint kinase 1 | -0.00609838 |
| AK5 | adenylate kinase 5 | -0.00608913 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00608675 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00607965 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.00607561 |
| BEX4 | brain expressed, X-linked 4 | -0.0060468 |
| DAZAP2 | DAZ associated protein 2 | -0.00603574 |
| UMOD | uromodulin | -0.00600588 |
| BTG3 | BTG family, member 3 | -0.00600246 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00598967 |
| ABLIM1 | actin binding LIM protein 1 | -0.00598562 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.00598522 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00598418 |
| NCK1 | NCK adaptor protein 1 | -0.0059694 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00596651 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.00596276 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.0059592 |
| VCAN | versican | -0.00593584 |
| PDE8B | phosphodiesterase 8B | -0.00593381 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00593294 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00593135 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | -0.00591559 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.00590959 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00589432 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0058803 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00587979 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00587932 |
| NME5 | NME/NM23 family member 5 | -0.00587767 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.00586897 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00586583 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | -0.00586199 |
| TFCP2L1 | transcription factor CP2-like 1 | -0.00584887 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00584759 |
| DCN | decorin | -0.00583461 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00582481 |
| TFDP1 | transcription factor Dp-1 | -0.00581284 |
| FABP1 | fatty acid binding protein 1, liver | -0.00581099 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | -0.00580459 |
| MUC16 | mucin 16, cell surface associated | -0.00580273 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00579187 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.00579063 |
| MBD2 | methyl-CpG binding domain protein 2 | -0.00578567 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0057697 |
| HBB | hemoglobin, beta | -0.00574215 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00573399 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | -0.00573396 |
| CAB39 | calcium binding protein 39 | -0.00572539 |
| VSNL1 | visinin-like 1 | -0.00572389 |
| TMEM38B | transmembrane protein 38B | -0.00570028 |
| GLDC | glycine dehydrogenase (decarboxylating) | -0.00569047 |
| LEPR | leptin receptor | -0.00568641 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00566407 |
| GPM6B | glycoprotein M6B | -0.00565977 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00565638 |
| GOLGA7 | golgin A7 | -0.00565219 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00563488 |
| PBK | PDZ binding kinase | -0.00562467 |
| HCRTR1 | hypocretin (orexin) receptor 1 | -0.00562365 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00560702 |
| CLINT1 | clathrin interactor 1 | -0.00559778 |
| ERLIN2 | ER lipid raft associated 2 | -0.00555343 |
| NRN1 | neuritin 1 | -0.00553281 |
| SDC2 | syndecan 2 | -0.00552137 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00550471 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | -0.0055034 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00549805 |
| DMD | dystrophin | -0.00549488 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00549458 |
| SEH1L | SEH1-like (S. cerevisiae) | -0.0054935 |
| KLHDC8A | kelch domain containing 8A | -0.00547945 |
| LEFTY1 | left-right determination factor 1 | -0.005479 |
| HYAL1 | hyaluronoglucosaminidase 1 | -0.00547711 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0054601 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00544705 |
