IFNG Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description interferon, gamma|This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.[provided by RefSeq, Nov 2009] (NCBI Entrez Gene Database, 3458)
External Link https://ncbi.nlm.nih.gov/gene/3458
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Genes

500 genes differentially expressed following the IFNG gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TSPAN8 tetraspanin 8 0.0103042
ITM2A integral membrane protein 2A 0.00995841
CLDN10 claudin 10 0.00987361
TFRC transferrin receptor 0.00881272
HNMT histamine N-methyltransferase 0.00860922
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00838251
TYRP1 tyrosinase-related protein 1 0.00810743
C1ORF115 chromosome 1 open reading frame 115 0.00769586
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00765953
ATF3 activating transcription factor 3 0.00752219
CHN2 chimerin 2 0.00750603
LY75 lymphocyte antigen 75 0.00739294
ISG15 ISG15 ubiquitin-like modifier 0.00735002
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.0072318
DAPK1 death-associated protein kinase 1 0.00711563
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00707751
KLK6 kallikrein-related peptidase 6 0.00707453
ASS1 argininosuccinate synthase 1 0.00703393
LGALS13 lectin, galactoside-binding, soluble, 13 0.00700451
PEG3 paternally expressed 3 0.0069553
AKR1C3 aldo-keto reductase family 1, member C3 0.00685795
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00683339
CD99 CD99 molecule 0.00678563
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00678463
LPAR1 lysophosphatidic acid receptor 1 0.00678347
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.0066966
PIR pirin (iron-binding nuclear protein) 0.0066791
HBB hemoglobin, beta 0.0066398
GSTO1 glutathione S-transferase omega 1 0.00661796
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00657175
GPR137B G protein-coupled receptor 137B 0.00656934
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00651819
GUSBP3 glucuronidase, beta pseudogene 3 0.00648906
NID2 nidogen 2 (osteonidogen) 0.00645252
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00642986
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.0063932
ABHD4 abhydrolase domain containing 4 0.00628549
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00624826
CXCL2 chemokine (C-X-C motif) ligand 2 0.00624204
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00622458
AGR2 anterior gradient 2 0.00618076
KYNU kynureninase 0.00616028
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00615047
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00610862
CYBRD1 cytochrome b reductase 1 0.00608923
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.0059981
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00598461
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00597532
UXT ubiquitously-expressed, prefoldin-like chaperone 0.00597148
CD300A CD300a molecule 0.00596641
TMC5 transmembrane channel-like 5 0.00595058
CLDN8 claudin 8 0.00592802
MME membrane metallo-endopeptidase 0.00592404
SCGB2A1 secretoglobin, family 2A, member 1 0.00591137
CYBA cytochrome b-245, alpha polypeptide 0.00580854
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.00573755
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00572034
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00571547
CCL20 chemokine (C-C motif) ligand 20 0.00567547
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.00566658
TXN thioredoxin 0.00566616
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 0.00565164
IFI44L interferon-induced protein 44-like 0.00564846
PIP prolactin-induced protein 0.00560234
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.00557363
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00557098
GJA1 gap junction protein, alpha 1, 43kDa 0.00555836
CREB3L1 cAMP responsive element binding protein 3-like 1 0.00554994
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.00553982
IFI27 interferon, alpha-inducible protein 27 0.00552757
IL15 interleukin 15 0.00551543
ACAT2 acetyl-CoA acetyltransferase 2 0.00550583
AHR aryl hydrocarbon receptor 0.00550158
BIRC3 baculoviral IAP repeat containing 3 0.00548956
ALCAM activated leukocyte cell adhesion molecule 0.00547814
SPON1 spondin 1, extracellular matrix protein 0.00546534
LDB2 LIM domain binding 2 0.00542279
KIAA0125 KIAA0125 0.00540962
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00540889
CP ceruloplasmin (ferroxidase) 0.00537181
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00533617
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00528873
SLC44A4 solute carrier family 44, member 4 0.00528572
CCP110 centriolar coiled coil protein 110kDa 0.00528419
ACSL5 acyl-CoA synthetase long-chain family member 5 0.00527911
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.00526832
EGR2 early growth response 2 0.00526376
RAI14 retinoic acid induced 14 0.00526345
TM4SF1 transmembrane 4 L six family member 1 0.00524642
ZMAT3 zinc finger, matrin-type 3 0.00523837
TCTA T-cell leukemia translocation altered 0.00523365
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00520176
AK4 adenylate kinase 4 0.00519677
SELL selectin L 0.00519449
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00518781
GPX2 glutathione peroxidase 2 0.00518297
PRPS2 phosphoribosyl pyrophosphate synthetase 2 0.00517658
SH3BP4 SH3-domain binding protein 4 0.00515728
ADGRG2 adhesion G protein-coupled receptor G2 0.0051498
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00514954
DEFB1 defensin, beta 1 0.00514947
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 0.00511944
PRR5L proline rich 5 like 0.00510645
STAC SH3 and cysteine rich domain 0.00510116
ETNK1 ethanolamine kinase 1 0.00509702
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00508182
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.00507796
C2CD2 C2 calcium-dependent domain containing 2 0.00505934
NAV3 neuron navigator 3 0.00504923
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 0.00503437
CADPS2 Ca++-dependent secretion activator 2 0.00503429
JAM2 junctional adhesion molecule 2 0.00502468
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00502397
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00501953
OXTR oxytocin receptor 0.00501701
LAT2 linker for activation of T cells family, member 2 0.00501212
CD86 CD86 molecule 0.00498761
CTTN cortactin 0.00498548
IFI44 interferon-induced protein 44 0.00498069
CCL22 chemokine (C-C motif) ligand 22 0.00495047
FGF1 fibroblast growth factor 1 (acidic) 0.00494152
PFKP phosphofructokinase, platelet 0.00494102
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.0049133
LMCD1 LIM and cysteine-rich domains 1 0.00490369
PELO pelota homolog (Drosophila) 0.00490062
DOK5 docking protein 5 0.00489735
IL6 interleukin 6 0.00489573
CA2 carbonic anhydrase II 0.00488098
CLIC5 chloride intracellular channel 5 0.00485848
TSC22D1 TSC22 domain family, member 1 0.00484967
MRPS30 mitochondrial ribosomal protein S30 0.00481262
VNN1 vanin 1 0.00481226
GRB7 growth factor receptor-bound protein 7 0.00480536
SORD sorbitol dehydrogenase 0.00479567
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00477415
HLA-F major histocompatibility complex, class I, F 0.00474778
ZEB2 zinc finger E-box binding homeobox 2 0.0047332
COX7B cytochrome c oxidase subunit VIIb 0.00473054
CXCL8 chemokine (C-X-C motif) ligand 8 0.00472519
GPA33 glycoprotein A33 (transmembrane) 0.00471461
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00471394
LIMCH1 LIM and calponin homology domains 1 0.00470393
DAAM2 dishevelled associated activator of morphogenesis 2 0.00469752
MYBPC1 myosin binding protein C, slow type 0.0046875
GATA6 GATA binding protein 6 0.00468422
SH3GL3 SH3-domain GRB2-like 3 0.00467689
ABHD6 abhydrolase domain containing 6 0.00466163
YAP1 Yes-associated protein 1 0.00465997
FABP1 fatty acid binding protein 1, liver 0.004654
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00464485
RELN reelin 0.00464062
IQGAP2 IQ motif containing GTPase activating protein 2 0.00463173
C8ORF4 chromosome 8 open reading frame 4 0.00463137
HSPA2 heat shock 70kDa protein 2 0.00461114
HPGDS hematopoietic prostaglandin D synthase 0.00460996
TFPI2 tissue factor pathway inhibitor 2 0.00459643
STXBP6 syntaxin binding protein 6 (amisyn) 0.00458958
CD83 CD83 molecule 0.00458643
EPAS1 endothelial PAS domain protein 1 0.00458474
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00457977
FXYD3 FXYD domain containing ion transport regulator 3 0.00457787
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00457743
HSPB11 heat shock protein family B (small), member 11 0.00457194
SYNGR2 synaptogyrin 2 0.00457087
JPT1 Jupiter microtubule associated homolog 1 0.00456628
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00455485
RTP4 receptor (chemosensory) transporter protein 4 0.00454733
ADRB2 adrenoceptor beta 2, surface 0.0045465
OLFML3 olfactomedin-like 3 0.00454005
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00452797
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00452056
PUDP pseudouridine 5'-phosphatase 0.00451963
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.00450881
CNIH1 cornichon family AMPA receptor auxiliary protein 1 0.00450682
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00448337
MYRF myelin regulatory factor 0.00448005
GCLM glutamate-cysteine ligase, modifier subunit 0.00447977
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.00445899
HOPX HOP homeobox 0.00444457
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00444446
RAB9A RAB9A, member RAS oncogene family 0.00443883
CFAP20 cilia and flagella associated protein 20 0.00443702
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.00443313
ARL4A ADP-ribosylation factor-like 4A 0.00443236
MAGEA3 melanoma antigen family A3 0.00442221
NPY1R neuropeptide Y receptor Y1 0.00441904
CXCL12 chemokine (C-X-C motif) ligand 12 0.00441063
RMDN1 regulator of microtubule dynamics 1 0.00440752
NOTCH2NL notch 2 N-terminal like 0.00440153
KAZN kazrin, periplakin interacting protein 0.00439358
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.0043871
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 0.00438467
KLK8 kallikrein-related peptidase 8 0.00437708
SLIRP SRA stem-loop interacting RNA binding protein 0.00437527
ASPA aspartoacylase 0.00437328
GSTZ1 glutathione S-transferase zeta 1 0.00436981
STC1 stanniocalcin 1 0.00435792
MOBP myelin-associated oligodendrocyte basic protein 0.00435789
CLIC2 chloride intracellular channel 2 0.00435606
SAR1B secretion associated, Ras related GTPase 1B 0.00434185
C6ORF48 chromosome 6 open reading frame 48 0.00434163
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00432179
HFE hemochromatosis 0.00431491
LY86 lymphocyte antigen 86 0.00429906
HAPLN1 hyaluronan and proteoglycan link protein 1 0.00429813
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.00429572
OLFML2A olfactomedin-like 2A 0.00429007
NOS3 nitric oxide synthase 3 (endothelial cell) 0.00428759
EMX2 empty spiracles homeobox 2 0.00428484
HEPH hephaestin 0.00427321
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 0.00426387
IER5 immediate early response 5 0.00425882
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 0.00424659
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.00423945
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00423936
EVI2A ecotropic viral integration site 2A 0.00423839
GAL galanin/GMAP prepropeptide 0.00423294
RPS27L ribosomal protein S27-like 0.00422879
CHPT1 choline phosphotransferase 1 0.00422838
SLC46A3 solute carrier family 46, member 3 0.00422451
PAEP progestagen-associated endometrial protein 0.00421952
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.00421935
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00420896
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00420303
MX1 MX dynamin-like GTPase 1 0.00420114
ETNPPL ethanolamine-phosphate phospho-lyase 0.00420063
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.00419521
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.00419266
OGFRL1 opioid growth factor receptor-like 1 0.00419189
KLK11 kallikrein-related peptidase 11 0.0041785
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.0041677
ADAM12 ADAM metallopeptidase domain 12 0.00415768
DUSP2 dual specificity phosphatase 2 0.00415527
TWIST1 twist family bHLH transcription factor 1 0.00414462
BATF3 basic leucine zipper transcription factor, ATF-like 3 0.00414079
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00412676
OLFML1 olfactomedin-like 1 0.00412106
SF3B5 splicing factor 3b, subunit 5, 10kDa 0.00412027
C1ORF54 chromosome 1 open reading frame 54 0.00411852
IRF4 interferon regulatory factor 4 0.00411493
PLCL1 phospholipase C-like 1 0.00411156
HOXB2 homeobox B2 0.00410754
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00410726
GMFB glia maturation factor, beta 0.00410513
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) 0.00409303
TRIM32 tripartite motif containing 32 0.00409217
LITAF lipopolysaccharide-induced TNF factor 0.00408901
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.00408639
TGFBR3 transforming growth factor, beta receptor III 0.00408017
ELOB elongin B 0.00407434

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -0.0103313
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00964267
CFD complement factor D (adipsin) -0.00961986
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00908529
KRT6A keratin 6A, type II -0.00898829
MGP matrix Gla protein -0.00870374
KRT5 keratin 5, type II -0.00856451
CRYBG1 crystallin beta-gamma domain containing 1 -0.00829376
KRT16 keratin 16, type I -0.00811441
CHD7 chromodomain helicase DNA binding protein 7 -0.00807627
CKAP4 cytoskeleton-associated protein 4 -0.00783008
PDIA3 protein disulfide isomerase family A, member 3 -0.00749229
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00741817
SIRT3 sirtuin 3 -0.00736432
AUTS2 autism susceptibility candidate 2 -0.00727707
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00724918
BAMBI BMP and activin membrane-bound inhibitor -0.00715661
KRT6B keratin 6B, type II -0.00715617
CSTA cystatin A (stefin A) -0.00690682
SPRR1B small proline-rich protein 1B -0.00671561
CAST calpastatin -0.00664955
TGFB1 transforming growth factor, beta 1 -0.00657422
SFRP1 secreted frizzled-related protein 1 -0.00652555
BEX1 brain expressed, X-linked 1 -0.0064082
VPREB3 pre-B lymphocyte 3 -0.00627149
AEBP1 AE binding protein 1 -0.00626801
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00617041
DGS2 DiGeorge syndrome/velocardiofacial syndrome complex 2 -0.00608645
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00600863
PKP1 plakophilin 1 -0.00599729
CCDC92 coiled-coil domain containing 92 -0.00598458
FGFBP1 fibroblast growth factor binding protein 1 -0.00591578
PAX5 paired box 5 -0.00590393
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.00589985
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00587932
TLE4 transducin-like enhancer of split 4 -0.00583683
FABP4 fatty acid binding protein 4, adipocyte -0.00580346
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.00579348
PRDX2 peroxiredoxin 2 -0.00569358
FBXO11 F-box protein 11 -0.00566878
KANK1 KN motif and ankyrin repeat domains 1 -0.00566321
PEG10 paternally expressed 10 -0.00563009
MMP1 matrix metallopeptidase 1 -0.00562857
OSBPL10 oxysterol binding protein-like 10 -0.00562671
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00558164
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -0.00557867
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00554613
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00552746
ACTN1 actinin, alpha 1 -0.00551864
SPRR2B small proline-rich protein 2B -0.00551739
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00549973
KRT15 keratin 15, type I -0.00549012
TNC tenascin C -0.00547915
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -0.00547363
CRCT1 cysteine-rich C-terminal 1 -0.00546806
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -0.00546217
ISL1 ISL LIM homeobox 1 -0.0054309
SDC1 syndecan 1 -0.00542972
FSD1 fibronectin type III and SPRY domain containing 1 -0.00542238
TARDBP TAR DNA binding protein -0.00541565
TGFA transforming growth factor, alpha -0.00541217
SFN stratifin -0.00535046
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00533342
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.0053293
POSTN periostin, osteoblast specific factor -0.00529815
LTB lymphotoxin beta (TNF superfamily, member 3) -0.00529089
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00528806
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00528519
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00528371
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00527299
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00525036
FBN2 fibrillin 2 -0.00524962
SPRR1A small proline-rich protein 1A -0.0052429
PTK2 protein tyrosine kinase 2 -0.00521391
TPP1 tripeptidyl peptidase I -0.00519453
MAST2 microtubule associated serine/threonine kinase 2 -0.00519003
RRBP1 ribosome binding protein 1 -0.00517045
FLNA filamin A, alpha -0.0051689
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -0.00515338
YME1L1 YME1-like 1 ATPase -0.00514952
MMP2 matrix metallopeptidase 2 -0.0050986
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00509556
GLG1 golgi glycoprotein 1 -0.00509147
C1R complement component 1, r subcomponent -0.00508978
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.00508162
CS citrate synthase -0.00507009
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00506752
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -0.00505976
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00504347
PLXNA1 plexin A1 -0.0050087
GZMK granzyme K (granzyme 3; tryptase II) -0.00499893
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.00499659
S100A2 S100 calcium binding protein A2 -0.0049946
CANT1 calcium activated nucleotidase 1 -0.00498893
FUBP1 far upstream element (FUSE) binding protein 1 -0.00497331
NOSIP nitric oxide synthase interacting protein -0.00496641
SQLE squalene epoxidase -0.00493149
FBLN1 fibulin 1 -0.00491802
RBM34 RNA binding motif protein 34 -0.00491469
TACC2 transforming, acidic coiled-coil containing protein 2 -0.00491017
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -0.00490405
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.00489625
NBPF10 neuroblastoma breakpoint family, member 10 -0.0048921
ESYT1 extended synaptotagmin-like protein 1 -0.00489081
SUN1 Sad1 and UNC84 domain containing 1 -0.00488768
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.00488709
CLCA2 chloride channel accessory 2 -0.00488312
RAD23B RAD23 homolog B (S. cerevisiae) -0.00487132
BGN biglycan -0.00485781
PYGB phosphorylase, glycogen; brain -0.00485779
NUCB1 nucleobindin 1 -0.00485359
C1QA complement component 1, q subcomponent, A chain -0.00483778
MAP2 microtubule-associated protein 2 -0.00483694
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00483015
SORBS1 sorbin and SH3 domain containing 1 -0.00482475
ERP29 endoplasmic reticulum protein 29 -0.00482041
KLF5 Kruppel-like factor 5 (intestinal) -0.00481477
NAV2 neuron navigator 2 -0.00479262
STXBP2 syntaxin binding protein 2 -0.00478604
HOMER3 homer scaffolding protein 3 -0.00478195
DLX5 distal-less homeobox 5 -0.0047645
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.0047631
TMX4 thioredoxin-related transmembrane protein 4 -0.00475819
VWF von Willebrand factor -0.00474923
IVL involucrin -0.00474397
DKK3 dickkopf WNT signaling pathway inhibitor 3 -0.00472872
CHGB chromogranin B -0.00471755
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -0.00471487
HYOU1 hypoxia up-regulated 1 -0.00470526
BRD4 bromodomain containing 4 -0.00470491
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00470207
DACH1 dachshund family transcription factor 1 -0.00467017
PKM pyruvate kinase, muscle -0.00466707
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.00466375
SCG5 secretogranin V -0.00465378
ENAH enabled homolog (Drosophila) -0.00463992
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00463261
IFT57 intraflagellar transport 57 -0.0046296
RNASE3 ribonuclease, RNase A family, 3 -0.00462717
FUS FUS RNA binding protein -0.00460968
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase -0.00460474
SMC6 structural maintenance of chromosomes 6 -0.00460425
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00459013
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00458339
TIMELESS timeless circadian clock -0.00457881
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 -0.0045784
DVL1 dishevelled segment polarity protein 1 -0.00457607
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00457403
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -0.00455529
TSPAN4 tetraspanin 4 -0.00455333
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00455235
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.00454574
HSPA13 heat shock protein 70kDa family, member 13 -0.00453668
INA internexin neuronal intermediate filament protein, alpha -0.00452588
SOBP sine oculis binding protein homolog (Drosophila) -0.00451675
PLXNA2 plexin A2 -0.00448793
TMEM45A transmembrane protein 45A -0.00448773
EGR1 early growth response 1 -0.00448478
HIRA histone cell cycle regulator -0.00448026
TMCC1 transmembrane and coiled-coil domain family 1 -0.00447864
FHL1 four and a half LIM domains 1 -0.0044752
AKAP8 A kinase (PRKA) anchor protein 8 -0.00445926
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.00445741
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00445432
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.00443913
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00441142
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00440712
DENND2D DENN/MADD domain containing 2D -0.00440014
STXBP1 syntaxin binding protein 1 -0.00439593
S100A8 S100 calcium binding protein A8 -0.00438863
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -0.00437639
C1QB complement component 1, q subcomponent, B chain -0.00437257
PLTP phospholipid transfer protein -0.00436945
PTHLH parathyroid hormone-like hormone -0.00436222
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00433348
SNRPA small nuclear ribonucleoprotein polypeptide A -0.00432327
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00431252
TMEM214 transmembrane protein 214 -0.00430342
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.00428988
SFTPD surfactant protein D -0.00428932
SLC35E2B solute carrier family 35, member E2B -0.00428718
NPEPL1 aminopeptidase-like 1 -0.00427731
LTBP1 latent transforming growth factor beta binding protein 1 -0.00425717
CD79A CD79a molecule, immunoglobulin-associated alpha -0.00424742
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00424597
ELANE elastase, neutrophil expressed -0.00424043
TSPAN13 tetraspanin 13 -0.0042367
LTA4H leukotriene A4 hydrolase -0.00422717
COL1A2 collagen, type I, alpha 2 -0.00420561
HRASLS HRAS-like suppressor -0.00420499
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -0.00419496
MICALL1 MICAL-like 1 -0.00419395
HIP1 huntingtin interacting protein 1 -0.00419084
C1S complement component 1, s subcomponent -0.00419079
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00418955
TCERG1 transcription elongation regulator 1 -0.0041887
CRNKL1 crooked neck pre-mRNA splicing factor 1 -0.00417156
PLIN1 perilipin 1 -0.00416984
ADAM22 ADAM metallopeptidase domain 22 -0.00415007
DAPK3 death-associated protein kinase 3 -0.00414509
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00414086
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -0.00413631
PNPLA2 patatin-like phospholipase domain containing 2 -0.00413229
CD9 CD9 molecule -0.00413181
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.00411798
PTMS parathymosin -0.00411528
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00411018
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00410533
FAM3C family with sequence similarity 3, member C -0.00410428
ITGA7 integrin, alpha 7 -0.00410096
ULK1 unc-51 like autophagy activating kinase 1 -0.0040977
S100A12 S100 calcium binding protein A12 -0.00409597
G6PD glucose-6-phosphate dehydrogenase -0.00409389
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00408912
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00408525
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00407638
H1-0 H1.0 linker histone -0.00406927
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00406104
PTPRA protein tyrosine phosphatase, receptor type, A -0.00405676
EMP1 epithelial membrane protein 1 -0.00405282
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.0040495
CAMTA1 calmodulin binding transcription activator 1 -0.00404877
CTSB cathepsin B -0.00404088
GANAB glucosidase, alpha; neutral AB -0.00403182
CRABP2 cellular retinoic acid binding protein 2 -0.00402532
ZCCHC14 zinc finger, CCHC domain containing 14 -0.00402487
SOX11 SRY (sex determining region Y)-box 11 -0.00402414
BSG basigin (Ok blood group) -0.00401508
UBE2N ubiquitin-conjugating enzyme E2N -0.00401321
SVIL supervillin -0.0040098
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00400846
THBS4 thrombospondin 4 -0.00399694
ZHX2 zinc fingers and homeoboxes 2 -0.00399321
CDA cytidine deaminase -0.00399012
LTBP2 latent transforming growth factor beta binding protein 2 -0.00397746
TAGLN transgelin -0.00397725
RAB11A RAB11A, member RAS oncogene family -0.00397492
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00396845
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.00396698
ZSWIM8 zinc finger, SWIM-type containing 8 -0.00396388
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor -0.00395561
NCAM1 neural cell adhesion molecule 1 -0.00395561
SPRR3 small proline-rich protein 3 -0.00394211
CAPZB capping protein (actin filament) muscle Z-line, beta -0.00394141
PLXNB2 plexin B2 -0.00394135
FASN fatty acid synthase -0.00393525
JCHAIN joining chain of multimeric IgA and IgM -0.00393389
CAB39 calcium binding protein 39 -0.00393343
RTL8C retrotransposon Gag like 8C -0.00392926
NCAPG2 non-SMC condensin II complex, subunit G2 -0.00392484