IKBKB Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta|The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011] (NCBI Entrez Gene Database, 3551)
Similar Terms
Downloads & Tools

Genes

436 genes differentially expressed following the IKBKB gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
LCMT2 leucine carboxyl methyltransferase 2 4.24152
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 4.24152
PCDHB4 protocadherin beta 4 4.24152
MBLAC1 metallo-beta-lactamase domain containing 1 4.24152
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 4.24152
SYNPO2L synaptopodin 2-like 4.24152
PEAR1 platelet endothelial aggregation receptor 1 4.24152
FOXR1 forkhead box R1 4.24152
PAX5 paired box 5 4.24152
SLC15A5 solute carrier family 15, member 5 4.24152
BMP8A bone morphogenetic protein 8a 4.24152
TCL1A T-cell leukemia/lymphoma 1A 4.24152
OLIG1 oligodendrocyte transcription factor 1 4.24152
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 4.24152
COL8A1 collagen, type VIII, alpha 1 4.24152
RAI2 retinoic acid induced 2 4.24152
LRRTM2 leucine rich repeat transmembrane neuronal 2 4.24152
OR2A1 olfactory receptor, family 2, subfamily A, member 1 4.24152
ELAVL4 ELAV like neuron-specific RNA binding protein 4 4.24152
KBTBD12 kelch repeat and BTB (POZ) domain containing 12 4.24152
SMOC1 SPARC related modular calcium binding 1 4.24152
CFHR3 complement factor H-related 3 4.24152
GJA5 gap junction protein, alpha 5, 40kDa 4.24152
LHCGR luteinizing hormone/choriogonadotropin receptor 4.24152
CD96 CD96 molecule 4.24152
MYO7A myosin VIIA 4.24152
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 4.24152
VTN vitronectin 4.24152
CDH9 cadherin 9, type 2 (T1-cadherin) 4.24152
ZNF491 zinc finger protein 491 4.24152
PI16 peptidase inhibitor 16 4.24152
ASB12 ankyrin repeat and SOCS box containing 12 4.24152
TUBB1 tubulin, beta 1 class VI 4.24152
IQCC IQ motif containing C 4.24152
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 4.24152
LRRC66 leucine rich repeat containing 66 4.24152
PGBD4 piggyBac transposable element derived 4 4.24152
TMC8 transmembrane channel-like 8 4.24152
SP6 Sp6 transcription factor 4.24152
CSNK2A3 casein kinase 2, alpha 3 polypeptide 4.24152
PODNL1 podocan-like 1 4.24152
SPON2 spondin 2, extracellular matrix protein 4.24152
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 4.24152
PLA2G10 phospholipase A2, group X 4.24152
LHX1 LIM homeobox 1 4.24152
MIXL1 Mix paired-like homeobox 4.24152
FGF8 fibroblast growth factor 8 (androgen-induced) 4.24152
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like 4.24152
PRSS36 protease, serine, 36 4.24152
FAM86B2 family with sequence similarity 86, member B2 4.24152
SFXN3 sideroflexin 3 4.24152
TNIP3 TNFAIP3 interacting protein 3 4.24152
TRIM77 tripartite motif containing 77 4.24152
HAS1 hyaluronan synthase 1 4.24152
ADAMTSL2 ADAMTS-like 2 4.24152
GSG1 germ cell associated 1 4.24152
BHLHE40 basic helix-loop-helix family, member e40 4.24152
PCDH8 protocadherin 8 4.24152
SPNS2 spinster homolog 2 (Drosophila) 4.24152
RGPD4 RANBP2-like and GRIP domain containing 4 4.24152
OXCT2 3-oxoacid CoA transferase 2 4.24152
TTPA tocopherol (alpha) transfer protein 4.24152
CHL1 cell adhesion molecule L1-like 4.24152
ACRBP acrosin binding protein 4.24152
SPEGNB SPEG neighbor 4.24152
AANAT aralkylamine N-acetyltransferase 4.24152
GPR34 G protein-coupled receptor 34 4.24152
PNLIPRP2 pancreatic lipase-related protein 2 4.24152
PNLIPRP1 pancreatic lipase-related protein 1 4.24152
VN1R2 vomeronasal 1 receptor 2 4.24152
TRPC7 transient receptor potential cation channel, subfamily C, member 7 4.24152
ZNF221 zinc finger protein 221 4.24152
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 4.24152
TBC1D3L TBC1 domain family, member 3L 4.24152
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 4.24152
PROX2 prospero homeobox 2 4.24152
GRAP GRB2-related adaptor protein 4.24152
MAGIX MAGI family member, X-linked 4.24152
SPMAP1 sperm microtubule associated protein 1 4.24152
RAX2 retina and anterior neural fold homeobox 2 4.24152
ROPN1B rhophilin associated tail protein 1B 4.24152
TNS1-AS1 TNS1 antisense RNA 1 4.24152
KIF1C-AS1 KIF1C antisense RNA 1 4.24152
C1ORF232 chromosome 1 open reading frame 230 4.24152
SMIM45 small integral membrane protein 45 4.24152
SMIM35 small integral membrane protein 35 4.24152
MINDY4B MINDY family member 4B 4.24152
MUCL3 mucin like 3 4.24152
DNAAF6 dynein axonemal assembly factor 6 4.24152
TEX13C TEX13 family member C 4.24152
CRACDL CRACD like 4.24152
TENT5C terminal nucleotidyltransferase 5C 4.24152
SMIM38 small integral membrane protein 38 4.24152
CPHXL2 cytoplasmic polyadenylated homeobox like 2 4.24152
GIPC3 GIPC PDZ domain containing family, member 3 4.24152
SPATC1 spermatogenesis and centriole associated 1 4.24152
CDKL4 cyclin-dependent kinase-like 4 4.24152
GOLGA6L4 golgin A6 family-like 4 4.24152
CD48 CD48 molecule 4.24152
PEX12 peroxisomal biogenesis factor 12 4.24152
AMBP alpha-1-microglobulin/bikunin precursor 4.24152
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 4.24152
ERVFRD-1 endogenous retrovirus group FRD, member 1 4.24152
LCAT lecithin-cholesterol acyltransferase 4.24152
IRF8 interferon regulatory factor 8 4.24152
MAGEB1 melanoma antigen family B1 4.24152
STAR steroidogenic acute regulatory protein 4.24152
CFAP99 cilia and flagella associated protein 99 4.24152
PCDHB10 protocadherin beta 10 4.24152
OR1F1 olfactory receptor, family 1, subfamily F, member 1 4.24152
IL15RA interleukin 15 receptor, alpha 4.24152
CD79A CD79a molecule, immunoglobulin-associated alpha 4.24152
CATSPER3 cation channel, sperm associated 3 4.24152
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 4.24152
DYNAP dynactin associated protein 4.24152
GDF5 growth differentiation factor 5 4.24152
GDF9 growth differentiation factor 9 4.24152
ZAR1L zygote arrest 1-like 4.24152
PLB1 phospholipase B1 4.24152
OVOL1 ovo-like zinc finger 1 4.24152
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 4.24152
RNF113B ring finger protein 113B 4.24152
BHLHA9 basic helix-loop-helix family, member a9 4.24152
ADGRG1 adhesion G protein-coupled receptor G1 4.24152
INAFM1 InaF-motif containing 1 4.24152
IL6 interleukin 6 4.24152
C1ORF167 chromosome 1 open reading frame 167 4.24152
PCDHA5 protocadherin alpha 5 4.24152
SMCO2 single-pass membrane protein with coiled-coil domains 2 4.24152
TMEM187 transmembrane protein 187 4.24152
LRRC43 leucine rich repeat containing 43 4.24152
CD200R1 CD200 receptor 1 4.24152
CTF1 cardiotrophin 1 4.24152
PSD pleckstrin and Sec7 domain containing 4.24152
CRYBA4 crystallin, beta A4 4.24152
ZNF703 zinc finger protein 703 4.24152
DNAH12 dynein, axonemal, heavy chain 12 4.24152
DYDC1 DPY30 domain containing 1 4.24152
NLRC5 NLR family, CARD domain containing 5 4.24152
MXRA5 matrix-remodelling associated 5 4.24152
GAL3ST2 galactose-3-O-sulfotransferase 2 4.24152
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) 4.24152
RPA4 replication protein A4, 30kDa 4.24152
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 4.24152
NGFR nerve growth factor receptor 4.24152
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 4.24152
RBM20 RNA binding motif protein 20 4.24152
GPR62 G protein-coupled receptor 62 4.24152
PRH2 proline-rich protein HaeIII subfamily 2 4.24152
CASS4 Cas scaffolding protein family member 4 4.24152
C17ORF107 chromosome 17 open reading frame 107 4.24152
ALAS2 5'-aminolevulinate synthase 2 4.24152
PCDHGB5 protocadherin gamma subfamily B, 5 4.24152
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 4.24152
RELN reelin 4.24152
NOX3 NADPH oxidase 3 4.24152
RTBDN retbindin 4.24152
LRRIQ3 leucine-rich repeats and IQ motif containing 3 4.24152
SLC47A2 solute carrier family 47 (multidrug and toxin extrusion), member 2 4.24152
SLC22A24 solute carrier family 22, member 24 4.24152
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 4.24152
CGB7 chorionic gonadotropin, beta polypeptide 7 4.24152
FAM209B family with sequence similarity 209, member B 4.24152
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 4.24152
CER1 cerberus 1, DAN family BMP antagonist 4.24152
GCOM1 GRINL1A complex locus 1 4.24152
S100Z S100 calcium binding protein Z 4.24152
ALS2CL ALS2 C-terminal like 4.24152
DPH1 diphthamide biosynthesis 1 4.24152
IL1A interleukin 1, alpha 4.24152
MLIP muscular LMNA-interacting protein 4.24152
AMIGO1 adhesion molecule with Ig-like domain 1 4.24152
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 4.24152
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 4.24152
ADGRA2 adhesion G protein-coupled receptor A2 4.24152
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 4.24152
KLHL6 kelch-like family member 6 4.24152
CRYBB2 crystallin, beta B2 4.24152
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 4.24152
ANKRD62 ankyrin repeat domain 62 4.24152
TECRL trans-2,3-enoyl-CoA reductase-like 4.24152
ZNF831 zinc finger protein 831 4.24152
FLNC filamin C, gamma 4.24152
GPR179 G protein-coupled receptor 179 4.24152
DENND2D DENN/MADD domain containing 2D 4.24152
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 4.24152
DNAH6 dynein, axonemal, heavy chain 6 4.24152
ANXA1 annexin A1 4.24152
MEPE matrix extracellular phosphoglycoprotein 4.24152
AMDHD1 amidohydrolase domain containing 1 4.24152
ZNF829 zinc finger protein 829 4.24152
MEIS1 Meis homeobox 1 4.24152
TMPRSS13 transmembrane protease, serine 13 4.24152
GJC2 gap junction protein, gamma 2, 47kDa 4.24152
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 4.24152
CYSRT1 cysteine-rich tail protein 1 4.24152
PSD4 pleckstrin and Sec7 domain containing 4 4.24152
WNK4 WNK lysine deficient protein kinase 4 4.24152
IQSEC3 IQ motif and Sec7 domain 3 4.24152
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 4.24152
TFCP2L1 transcription factor CP2-like 1 4.24152
NRG4 neuregulin 4 4.24152
CFB complement factor B 4.24152
MAGEC3 melanoma antigen family C3 4.24152
NLRP9 NLR family, pyrin domain containing 9 4.24152
KIF19 kinesin family member 19 4.24152
GGN gametogenetin 4.24152
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 4.24152
ESPNL espin-like 4.24152
GPBAR1 G protein-coupled bile acid receptor 1 4.24152
EFCAB12 EF-hand calcium binding domain 12 4.24152
VTCN1 V-set domain containing T cell activation inhibitor 1 4.24152
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 4.24152
CDH26 cadherin 26 4.24152
MOB4 MOB family member 4, phocein 4.24152
SLC25A34 solute carrier family 25, member 34 4.24152
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 4.24152
GFY golgi-associated, olfactory signaling regulator 4.24152
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 4.24152
CARD9 caspase recruitment domain family, member 9 4.24152
CDPF1 cysteine-rich, DPF motif domain containing 1 4.24152
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 4.24152
CD80 CD80 molecule 4.24152
CLPSL1 colipase-like 1 4.24152
CD27 CD27 molecule 4.24152
CAPN10 calpain 10 4.19402
TBC1D25 TBC1 domain family, member 25 4.19402
SMAD7 SMAD family member 7 4.19402
RWDD2B RWD domain containing 2B 4.19402
ESYT3 extended synaptotagmin-like protein 3 4.14741
IL17RC interleukin 17 receptor C 4.14741
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 4.14741
A4GALT alpha 1,4-galactosyltransferase 4.14741
ZBTB45 zinc finger and BTB domain containing 45 3.97396
CNOT7 CCR4-NOT transcription complex, subunit 7 3.68842
RNF166 ring finger protein 166 3.64296
MAST3 microtubule associated serine/threonine kinase 3 3.64296
CFAP46 cilia and flagella associated protein 46 3.10987
RUBCNL rubicon like autophagy enhancer 3.10987
ADAM11 ADAM metallopeptidase domain 11 3.10987
AGER advanced glycosylation end product-specific receptor 3.10987
RPRML reprimo-like 3.10987
IQUB IQ motif and ubiquitin domain containing 3.10987
RNF207 ring finger protein 207 3.10987
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 3.10987
GPR82 G protein-coupled receptor 82 3.10987
MROH9 maestro heat-like repeat family member 9 3.10987
GUCA1A guanylate cyclase activator 1A (retina) 3.10987
USP27X ubiquitin specific peptidase 27, X-linked 3.10987
COL8A2 collagen, type VIII, alpha 2 3.10987
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 3.10987
MAP6D1 MAP6 domain containing 1 3.10987
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 3.10987
ZNF582 zinc finger protein 582 3.10987
RAB5B RAB5B, member RAS oncogene family 2.95023
RALBP1 ralA binding protein 1 2.91532
CCS copper chaperone for superoxide dismutase 2.80884
PPP1R35 protein phosphatase 1, regulatory subunit 35 2.76929
C5ORF58 chromosome 5 open reading frame 58 2.66233
CDC27 cell division cycle 27 2.61604
DPY19L4 dpy-19-like 4 (C. elegans) 2.6113
PRSS23 protease, serine, 23 2.58841
ACTA2 actin, alpha 2, smooth muscle, aorta 2.58601
PATL1 protein associated with topoisomerase II homolog 1 (yeast) 2.57393
ASB13 ankyrin repeat and SOCS box containing 13 2.52286
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 2.51731
LPIN3 lipin 3 2.50008
COPS6 COP9 signalosome subunit 6 2.49869
TTC12 tetratricopeptide repeat domain 12 2.48862
DEMA1 DPM1 ER membrane anchor 1 2.48862
CNKSR2 connector enhancer of kinase suppressor of Ras 2 2.48783
CDK17 cyclin-dependent kinase 17 2.4844
LDHB lactate dehydrogenase B 2.46096
BCAP29 B-cell receptor-associated protein 29 2.45045
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 2.39982
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 2.38778
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator 2.38778
SKIL SKI-like proto-oncogene 2.36972
SRI sorcin 2.35128
RND2 Rho family GTPase 2 2.33409
METTL2B methyltransferase like 2B 2.33184
STC1 stanniocalcin 1 2.30418
AURKB aurora kinase B 2.29356
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.27321
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.26719
RAB25 RAB25, member RAS oncogene family 2.23411
PFKM phosphofructokinase, muscle 2.23341
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 2.22412
CAT catalase 2.19845
ICMT isoprenylcysteine carboxyl methyltransferase 2.19512
PFDN5 prefoldin subunit 5 2.16021
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1 2.16021
ABHD4 abhydrolase domain containing 4 2.15842
NPEPPS aminopeptidase puromycin sensitive 2.12966
GOLGB1 golgin B1 2.11558
ABITRAM actin binding transcription modulator 2.10737
LMNB2 lamin B2 2.08826
REEP2 receptor accessory protein 2 2.06877
PCGF5 polycomb group ring finger 5 2.04085
E2F6 E2F transcription factor 6 2.03868
TRIM28 tripartite motif containing 28 2.03868
SURF6 surfeit 6 2.03834
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 2.0044

decreased expression

Symbol Name Standardized Value
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -4.24152
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 -4.24152
CCDC62 coiled-coil domain containing 62 -4.24152
DGKQ diacylglycerol kinase, theta 110kDa -4.24152
GPATCH11 G patch domain containing 11 -4.24152
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 -4.19402
PRSS27 protease, serine 27 -4.19402
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 -4.19402
EMX1 empty spiracles homeobox 1 -4.19402
SCX scleraxis basic helix-loop-helix transcription factor -4.19402
RHOV ras homolog family member V -4.19402
C7ORF25 chromosome 7 open reading frame 25 -4.19402
MYL5 myosin, light chain 5, regulatory -4.19402
FGF22 fibroblast growth factor 22 -4.19402
RUNDC3A RUN domain containing 3A -4.19402
PLA2G4B phospholipase A2, group IVB (cytosolic) -4.19402
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -4.19402
CNBD2 cyclic nucleotide binding domain containing 2 -4.19402
LIMS2 LIM and senescent cell antigen-like domains 2 -4.19402
CNTN3 contactin 3 (plasmacytoma associated) -4.19402
TDRD12 tudor domain containing 12 -4.19402
FBP2 fructose-1,6-bisphosphatase 2 -4.19402
SPDYE6 speedy/RINGO cell cycle regulator family member E6 -4.19402
PFN4 profilin family, member 4 -4.19402
TTC6 tetratricopeptide repeat domain 6 -4.19402
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 -4.19402
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 -4.19402
PAQR9 progestin and adipoQ receptor family member IX -4.19402
XKR9 XK, Kell blood group complex subunit-related family, member 9 -4.19402
RAB24 RAB24, member RAS oncogene family -4.19402
SPHKAP SPHK1 interactor, AKAP domain containing -4.19402
IGSF6 immunoglobulin superfamily, member 6 -4.19402
C12ORF42 chromosome 12 open reading frame 42 -4.19402
PCDHGA5 protocadherin gamma subfamily A, 5 -4.19402
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -4.19402
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 -4.19402
TMPRSS5 transmembrane protease, serine 5 -4.19402
ARC activity-regulated cytoskeleton-associated protein -4.19402
CHCT1 CHD1 helical C-terminal domain containing 1 -4.19402
EFNA1 ephrin-A1 -4.19402
ZNF44 zinc finger protein 44 -4.04454
ADORA2B adenosine A2b receptor -3.98244
ZNF341 zinc finger protein 341 -3.98244
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -3.8526
ZNF782 zinc finger protein 782 -3.58754
IER3 immediate early response 3 -3.55237
LRRC23 leucine rich repeat containing 23 -3.46469
MARK4 MAP/microtubule affinity-regulating kinase 4 -3.40547
ATP13A1 ATPase type 13A1 -3.3357
SZT2 seizure threshold 2 homolog (mouse) -3.32235
MARCHF4 membrane associated ring-CH-type finger 4 -3.32235
SPEG SPEG complex locus -3.30784
HSPA1A heat shock 70kDa protein 1A -3.23722
NDRG4 NDRG family member 4 -3.22675
DTX4 deltex 4, E3 ubiquitin ligase -3.06997
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.93183
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -2.9026
H2AC16 H2A clustered histone 16 -2.90044
PLAC8L1 PLAC8-like 1 -2.89991
ARMH1 armadillo like helical domain containing 1 -2.89991
CLVS1 clavesin 1 -2.89991
FAM222A family with sequence similarity 222, member A -2.89991
RHOBTB2 Rho-related BTB domain containing 2 -2.89991
CDX4 caudal type homeobox 4 -2.89991
USP30 ubiquitin specific peptidase 30 -2.89991
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -2.87591
MANBA mannosidase, beta A, lysosomal -2.84892
IDE insulin-degrading enzyme -2.82884
AFG2A AFG2 AAA ATPase homolog A -2.74748
YPEL1 yippee-like 1 (Drosophila) -2.74634
RBL1 retinoblastoma-like 1 -2.74545
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -2.74274
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.72734
ENTREP2 endosomal transmembrane epsin interactor 2 -2.70504
KATNA1 katanin p60 (ATPase containing) subunit A 1 -2.69401
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 -2.67359
SNF8 SNF8, ESCRT-II complex subunit -2.64495
PSD3 pleckstrin and Sec7 domain containing 3 -2.63799
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa -2.61989
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 -2.60358
PUS10 pseudouridylate synthase 10 -2.60358
EPDR1 ependymin related 1 -2.60358
LSAMP limbic system-associated membrane protein -2.59662
COPS7B COP9 signalosome subunit 7B -2.59662
IDS iduronate 2-sulfatase -2.58601
TEAD3 TEA domain family member 3 -2.58206
RORA RAR-related orphan receptor A -2.57706
MBTD1 mbt domain containing 1 -2.50033
DACT1 dishevelled-binding antagonist of beta-catenin 1 -2.48783
NCKAP5 NCK-associated protein 5 -2.4771
ERVMER34-1 endogenous retrovirus group MER34, member 1 -2.45771
SCRN1 secernin 1 -2.40917
FAS Fas cell surface death receptor -2.38803
DCLK3 doublecortin-like kinase 3 -2.38803
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 -2.38803
CNTNAP5 contactin associated protein-like 5 -2.38803
HASPIN histone H3 associated protein kinase -2.38803
ANKRD24 ankyrin repeat domain 24 -2.38803
UBE2A ubiquitin-conjugating enzyme E2A -2.37632
COP1 COP1 E3 ubiquitin ligase -2.37216
TLE2 transducin-like enhancer of split 2 -2.29356
MATN2 matrilin 2 -2.29356
PPP1R3F protein phosphatase 1, regulatory subunit 3F -2.29356
FST follistatin -2.292
ECHDC1 ethylmalonyl-CoA decarboxylase 1 -2.27321
BLTP3A bridge-like lipid transfer protein family member 3A -2.27321
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -2.27321
COG3 component of oligomeric golgi complex 3 -2.25814
ARL8B ADP-ribosylation factor-like 8B -2.2329
DNMBP dynamin binding protein -2.20839
HPS3 Hermansky-Pudlak syndrome 3 -2.20532
WNK2 WNK lysine deficient protein kinase 2 -2.20158
HELQ helicase, POLQ-like -2.18717
FANCL Fanconi anemia, complementation group L -2.12544
ZNF277 zinc finger protein 277 -2.12544
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -2.1123
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -2.09883
PCNX3 pecanex 3 -2.09883
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -2.09883
ATG14 autophagy related 14 -2.08851
RAD17 RAD17 homolog (S. pombe) -2.08851
UBTD1 ubiquitin domain containing 1 -2.08404
MCM2 minichromosome maintenance complex component 2 -2.07481
ZNF486 zinc finger protein 486 -2.07144
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -2.07144
NOAZFP nucleolar atypical zinc finger -2.07144
SSTR2 somatostatin receptor 2 -2.06384
AADAT aminoadipate aminotransferase -2.03479
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) -2.02617
WDR70 WD repeat domain 70 -2.02443
RCN1 reticulocalbin 1, EF-hand calcium binding domain -2.01779
PCTP phosphatidylcholine transfer protein -2.01778
AP1M2 adaptor-related protein complex 1, mu 2 subunit -2.00373