| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma|This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 8517) |
| External Link | https://ncbi.nlm.nih.gov/gene/8517 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the IKBKG gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COQ8A | coenzyme Q8A | 0.0203266 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.0152581 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.012015 |
| AOC1 | amine oxidase, copper containing 1 | 0.0119381 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.0118571 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0114868 |
| RB1 | retinoblastoma 1 | 0.0113031 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0104856 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00995333 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00981677 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00915675 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00915278 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0089818 |
| CD200 | CD200 molecule | 0.00880714 |
| FHL1 | four and a half LIM domains 1 | 0.00863235 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00862086 |
| EPHB2 | EPH receptor B2 | 0.00856644 |
| DCK | deoxycytidine kinase | 0.00851536 |
| KLK11 | kallikrein-related peptidase 11 | 0.00843843 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00836135 |
| HIST3H2A | histone cluster 3, H2a | 0.0081789 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00814052 |
| KLK10 | kallikrein-related peptidase 10 | 0.00813941 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00813238 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00810794 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00792805 |
| GATA6 | GATA binding protein 6 | 0.00791537 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00781952 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00764987 |
| NPR3 | natriuretic peptide receptor 3 | 0.00758695 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00757293 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00750154 |
| PGF | placental growth factor | 0.0074173 |
| TSPAN7 | tetraspanin 7 | 0.00737012 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00716317 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00707509 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.00694371 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | 0.00690635 |
| KIAA0125 | KIAA0125 | 0.00687031 |
| EGR1 | early growth response 1 | 0.00680422 |
| PFKP | phosphofructokinase, platelet | 0.00677153 |
| HOXB6 | homeobox B6 | 0.00673885 |
| TCTA | T-cell leukemia translocation altered | 0.00672359 |
| LOX | lysyl oxidase | 0.0066591 |
| GAB2 | GRB2-associated binding protein 2 | 0.00664294 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00663746 |
| CCN3 | cellular communication network factor 3 | 0.00662767 |
| TXNIP | thioredoxin interacting protein | 0.00661871 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00658503 |
| STMN2 | stathmin 2 | 0.00651331 |
| CALB1 | calbindin 1, 28kDa | 0.00649385 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00648427 |
| SELL | selectin L | 0.00646319 |
| MFAP5 | microfibrillar associated protein 5 | 0.00645399 |
| TCF12 | transcription factor 12 | 0.00641796 |
| MMP3 | matrix metallopeptidase 3 | 0.00641178 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.00636522 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00632777 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00625358 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00620765 |
| ADM | adrenomedullin | 0.00619676 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | 0.00619105 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.00618985 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | 0.00617633 |
| MECOM | MDS1 and EVI1 complex locus | 0.00606251 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00605663 |
| REG3A | regenerating islet-derived 3 alpha | 0.00601453 |
| GPX3 | glutathione peroxidase 3 | 0.00600753 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00600269 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00597603 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00596171 |
| FOXN3 | forkhead box N3 | 0.00593363 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.00592863 |
| PROM1 | prominin 1 | 0.00587321 |
| H1-2 | H1.2 linker histone, cluster member | 0.00585898 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial | 0.00583183 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00577964 |
| CCN2 | cellular communication network factor 2 | 0.00577621 |
| DNTT | DNA nucleotidylexotransferase | 0.00576964 |
| PTH2R | parathyroid hormone 2 receptor | 0.00575959 |
| NOX1 | NADPH oxidase 1 | 0.00575226 |
| MDFIC | MyoD family inhibitor domain containing | 0.00575194 |
| AOX1 | aldehyde oxidase 1 | 0.00572978 |
| TCF4 | transcription factor 4 | 0.00570284 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | 0.00567018 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00566291 |
| RHOB | ras homolog family member B | 0.00566059 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.00565643 |
| EHBP1 | EH domain binding protein 1 | 0.00562288 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00560531 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00560016 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00559462 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00557241 |
| AREG | amphiregulin | 0.00555642 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00554286 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.00553959 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.00553737 |
| TFF3 | trefoil factor 3 (intestinal) | 0.0055139 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00550218 |
| VIL1 | villin 1 | 0.00542066 |
| HPGDS | hematopoietic prostaglandin D synthase | 0.00541118 |
| PIGR | polymeric immunoglobulin receptor | 0.00540744 |
| TTN | titin | 0.00540323 |
| MMP12 | matrix metallopeptidase 12 | 0.00539476 |
| CD34 | CD34 molecule | 0.00539106 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00538426 |
| PLVAP | plasmalemma vesicle associated protein | 0.00536857 |
| ITGA6 | integrin, alpha 6 | 0.00533525 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00528829 |
| EDNRB | endothelin receptor type B | 0.00527946 |
| TMSB15A | thymosin beta 15a | 0.00527802 |
| H1-10 | H1.10 linker histone | 0.00526189 |
| MAB21L1 | mab-21-like 1 (C. elegans) | 0.00524734 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00523392 |
| AEBP1 | AE binding protein 1 | 0.00522195 |
| SELE | selectin E | 0.00522065 |
| KIF20A | kinesin family member 20A | 0.00521797 |
| TMEM176B | transmembrane protein 176B | 0.00521515 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00521364 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.00519647 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00519036 |
| UVRAG | UV radiation resistance associated | 0.00519012 |
| PLN | phospholamban | 0.00517523 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00517389 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00516858 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00516264 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.00515697 |
| MYO1B | myosin IB | 0.0051541 |
| GIPC2 | GIPC PDZ domain containing family, member 2 | 0.00515138 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00514944 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00514165 |
| DACH1 | dachshund family transcription factor 1 | 0.00514151 |
| QDPR | quinoid dihydropteridine reductase | 0.00513646 |
| HDGFL3 | HDGF like 3 | 0.00512979 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.00512955 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00512672 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00511997 |
| SLC46A3 | solute carrier family 46, member 3 | 0.00510661 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A | 0.00510042 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.00506337 |
| CALB2 | calbindin 2 | 0.00505586 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0050552 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00504362 |
| NDRG1 | N-myc downstream regulated 1 | 0.00502293 |
| STC1 | stanniocalcin 1 | 0.00501841 |
| VSNL1 | visinin-like 1 | 0.00501597 |
| NNT | nicotinamide nucleotide transhydrogenase | 0.00500961 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00499667 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.00499196 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | 0.00495426 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00495345 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00493696 |
| GAS1 | growth arrest-specific 1 | 0.00492971 |
| TMEM176A | transmembrane protein 176A | 0.00491714 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | 0.00491654 |
| CEP68 | centrosomal protein 68kDa | 0.00491512 |
| ASS1 | argininosuccinate synthase 1 | 0.0049114 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00491053 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00490982 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00490545 |
| TMEM135 | transmembrane protein 135 | 0.00490193 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.00489972 |
| YME1L1 | YME1-like 1 ATPase | 0.00489833 |
| COMP | cartilage oligomeric matrix protein | 0.00489673 |
| SLC25A46 | solute carrier family 25, member 46 | 0.00489552 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00489472 |
| DPY19L2P2 | DPY19L2 pseudogene 2 | 0.00487475 |
| GMPR2 | guanosine monophosphate reductase 2 | 0.00486314 |
| EMP1 | epithelial membrane protein 1 | 0.00486087 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0048608 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00484182 |
| TCAF1 | TRPM8 channel-associated factor 1 | 0.00483875 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00483145 |
| HOXB7 | homeobox B7 | 0.00482262 |
| POU4F1 | POU class 4 homeobox 1 | 0.0048226 |
| ATP10B | ATPase, class V, type 10B | 0.00481743 |
| XPO1 | exportin 1 | 0.00479832 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00479045 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 0.00478769 |
| CERS6 | ceramide synthase 6 | 0.00477488 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00476133 |
| LAMA4 | laminin, alpha 4 | 0.00475492 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00475266 |
| RTN2 | reticulon 2 | 0.00474509 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.00474338 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.00473351 |
| RCAN1 | regulator of calcineurin 1 | 0.00468688 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00468377 |
| CNTNAP2 | contactin associated protein-like 2 | 0.0046779 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00465863 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.00465484 |
| TPM2 | tropomyosin 2 (beta) | 0.00464513 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00463882 |
| GOLIM4 | golgi integral membrane protein 4 | 0.00463311 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00463183 |
| TSPAN6 | tetraspanin 6 | 0.00462988 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 0.00462642 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.0046256 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00462228 |
| TSPAN8 | tetraspanin 8 | 0.00461663 |
| ADD2 | adducin 2 (beta) | 0.00461612 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 0.00461408 |
| SHLD2 | shieldin complex subunit 2 | 0.00461218 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00461073 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.0045858 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00458251 |
| HIST1H2BD | histone cluster 1, H2bd | 0.0045785 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | 0.00457359 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00457017 |
| MYO1D | myosin ID | 0.00456789 |
| STATH | statherin | 0.00456654 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.00456106 |
| ARHGAP44 | Rho GTPase activating protein 44 | 0.0045599 |
| ACKR3 | atypical chemokine receptor 3 | 0.00455656 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00454056 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 0.0045383 |
| RASA4 | RAS p21 protein activator 4 | 0.00453659 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00453048 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00452909 |
| BTG2 | BTG family, member 2 | 0.00452317 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00452093 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00451755 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00451682 |
| ACE2 | angiotensin I converting enzyme 2 | 0.00451602 |
| HDAC9 | histone deacetylase 9 | 0.00449525 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00448122 |
| PRMT5 | protein arginine methyltransferase 5 | 0.00447943 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | 0.00446515 |
| TMEM70 | transmembrane protein 70 | 0.00446454 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00446428 |
| RFX7 | regulatory factor X, 7 | 0.00445903 |
| PFKM | phosphofructokinase, muscle | 0.00443624 |
| GUCY2C | guanylate cyclase 2C | 0.00443367 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00443269 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00443044 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00441757 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0044158 |
| ANK2 | ankyrin 2, neuronal | 0.00441186 |
| ANTXR1 | anthrax toxin receptor 1 | 0.00440546 |
| MEST | mesoderm specific transcript | 0.00440422 |
| H1-0 | H1.0 linker histone | 0.00440232 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00440222 |
| EMX2 | empty spiracles homeobox 2 | 0.00439503 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00439129 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00438865 |
| CDX1 | caudal type homeobox 1 | 0.00438393 |
| CLIC5 | chloride intracellular channel 5 | 0.00438128 |
| PCP4 | Purkinje cell protein 4 | 0.00438004 |
| HTRA2 | HtrA serine peptidase 2 | 0.00437913 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00437911 |
| Symbol | Name | Standardized Value |
|---|---|---|
| S100P | S100 calcium binding protein P | -0.0133637 |
| HOPX | HOP homeobox | -0.0121862 |
| STAP2 | signal transducing adaptor family member 2 | -0.0111936 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.0111378 |
| SRGN | serglycin | -0.0108675 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0107386 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0103281 |
| TLCD3A | TLC domain containing 3A | -0.0100481 |
| XIC | X chromosome inactivation center | -0.00981316 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00960265 |
| RGS1 | regulator of G-protein signaling 1 | -0.00926643 |
| CD52 | CD52 molecule | -0.00925214 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00921307 |
| MAGEA3 | melanoma antigen family A3 | -0.00901893 |
| S100A9 | S100 calcium binding protein A9 | -0.00900803 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0089733 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.008634 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00841558 |
| FN1 | fibronectin 1 | -0.00841104 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00834771 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.00832269 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00820262 |
| KRT7 | keratin 7, type II | -0.00818499 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00815241 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00806981 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0078886 |
| CLC | Charcot-Leyden crystal galectin | -0.00776035 |
| TOR1A | torsin family 1, member A (torsin A) | -0.00775688 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.0076544 |
| S100A8 | S100 calcium binding protein A8 | -0.00754566 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00746943 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00745091 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.0074139 |
| S100A11 | S100 calcium binding protein A11 | -0.00730872 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00719573 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00718476 |
| TMEM45A | transmembrane protein 45A | -0.00716989 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -0.00708793 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00705798 |
| TRIB3 | tribbles pseudokinase 3 | -0.00704808 |
| CSTA | cystatin A (stefin A) | -0.0070363 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00687252 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00687038 |
| PLBD1 | phospholipase B domain containing 1 | -0.00685214 |
| MLPH | melanophilin | -0.00683608 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00675625 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 | -0.00674792 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00669602 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00667094 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00666533 |
| CTSG | cathepsin G | -0.00664094 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00660557 |
| CD9 | CD9 molecule | -0.00660307 |
| KRT18 | keratin 18, type I | -0.00657829 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00647949 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | -0.00644573 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00644475 |
| KRT17 | keratin 17, type I | -0.00640307 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.00639532 |
| FZD2 | frizzled class receptor 2 | -0.00636344 |
| MMP9 | matrix metallopeptidase 9 | -0.00635084 |
| EMP3 | epithelial membrane protein 3 | -0.00630942 |
| TUBA1A | tubulin, alpha 1a | -0.00621346 |
| ABHD6 | abhydrolase domain containing 6 | -0.00618795 |
| KDSR | 3-ketodihydrosphingosine reductase | -0.00614694 |
| SDC4 | syndecan 4 | -0.00612535 |
| MYO6 | myosin VI | -0.00612404 |
| KRT19 | keratin 19, type I | -0.00610523 |
| PTN | pleiotrophin | -0.00603747 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00603095 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00602859 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.0060169 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.0059579 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00594501 |
| INAVA | innate immunity activator | -0.00593095 |
| ITM2A | integral membrane protein 2A | -0.00592286 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00591923 |
| SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | -0.00591262 |
| KYNU | kynureninase | -0.0059087 |
| NAV3 | neuron navigator 3 | -0.00589306 |
| LYZ | lysozyme | -0.00588992 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00588771 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00588249 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00586762 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00586369 |
| HAL | histidine ammonia-lyase | -0.00585185 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -0.00584311 |
| GSDME | gasdermin E | -0.00584104 |
| ABHD4 | abhydrolase domain containing 4 | -0.00582581 |
| ITGAV | integrin, alpha V | -0.00579919 |
| WIF1 | WNT inhibitory factor 1 | -0.00578892 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00578501 |
| NPY1R | neuropeptide Y receptor Y1 | -0.0057603 |
| MIR22HG | MIR22 host gene | -0.00575005 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.00574997 |
| DLD | dihydrolipoamide dehydrogenase | -0.00572403 |
| TP73-AS1 | TP73 antisense RNA 1 | -0.00568882 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.0056857 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00566647 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00566595 |
| MGP | matrix Gla protein | -0.005644 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00563582 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00561707 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00558543 |
| SFTPA2 | surfactant protein A2 | -0.005582 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00557671 |
| FZD10 | frizzled class receptor 10 | -0.00555008 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -0.00553574 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | -0.00553477 |
| GMFG | glia maturation factor, gamma | -0.00553343 |
| CES1 | carboxylesterase 1 | -0.00552753 |
| CYBB | cytochrome b-245, beta polypeptide | -0.0055089 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.00549406 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00545841 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00545372 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00544719 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00544374 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.00544351 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00541487 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00540545 |
| ANXA10 | annexin A10 | -0.00540255 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.00539839 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00539708 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00538833 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | -0.00538741 |
| MREG | melanoregulin | -0.00535447 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00531846 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.00531012 |
| CST6 | cystatin E/M | -0.0052921 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00528799 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.0052863 |
| CENPBD1P1 | CENPB DNA-binding domains containing 1 pseudogene 1 | -0.0052237 |
| ATG101 | autophagy related 101 | -0.00522023 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00520446 |
| ZNF175 | zinc finger protein 175 | -0.00518771 |
| HYOU1 | hypoxia up-regulated 1 | -0.00517753 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | -0.00517255 |
| SMOX | spermine oxidase | -0.00515416 |
| PERP | PERP, TP53 apoptosis effector | -0.00513915 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00512235 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00512218 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00508477 |
| ZIC1 | Zic family member 1 | -0.00507947 |
| ESR1 | estrogen receptor 1 | -0.00507307 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00507002 |
| KRT15 | keratin 15, type I | -0.00503104 |
| PIP | prolactin-induced protein | -0.00502946 |
| BARD1 | BRCA1 associated RING domain 1 | -0.00502088 |
| MATN2 | matrilin 2 | -0.0050184 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00500184 |
| NVL | nuclear VCP-like | -0.00499444 |
| PRR13 | proline rich 13 | -0.0049905 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | -0.00498839 |
| LOXL2 | lysyl oxidase-like 2 | -0.00498704 |
| HOMER1 | homer scaffolding protein 1 | -0.00498483 |
| RAB25 | RAB25, member RAS oncogene family | -0.00497107 |
| GPR137B | G protein-coupled receptor 137B | -0.00495183 |
| ELANE | elastase, neutrophil expressed | -0.00494499 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.0049341 |
| GNAS | GNAS complex locus | -0.0049136 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00490773 |
| TNIK | TRAF2 and NCK interacting kinase | -0.00488981 |
| GLTP | glycolipid transfer protein | -0.00488617 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 | -0.00487966 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00487728 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00487587 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00485352 |
| GOLGA8A | golgin A8 family, member A | -0.00485292 |
| NKX2-2 | NK2 homeobox 2 | -0.00484771 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.00484199 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00484012 |
| FICD | FIC domain containing | -0.00482456 |
| C3 | complement component 3 | -0.0048227 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00481724 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00480808 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00480769 |
| CHI3L2 | chitinase 3-like 2 | -0.00480547 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.00480501 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00480207 |
| MTFR1 | mitochondrial fission regulator 1 | -0.00476053 |
| KRT8 | keratin 8, type II | -0.00475709 |
| IRS2 | insulin receptor substrate 2 | -0.00475075 |
| ZNF512B | zinc finger protein 512B | -0.00470956 |
| CFD | complement factor D (adipsin) | -0.00470275 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.00468913 |
| ADAM8 | ADAM metallopeptidase domain 8 | -0.00468716 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -0.00465856 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00465834 |
| ATF3 | activating transcription factor 3 | -0.00465443 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.00465397 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00465377 |
| SFTPB | surfactant protein B | -0.00464914 |
| TEX30 | testis expressed 30 | -0.00464125 |
| GLRX2 | glutaredoxin 2 | -0.00462695 |
| WASHC4 | WASH complex subunit 4 | -0.00462547 |
| VNN1 | vanin 1 | -0.00462277 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00461822 |
| GOLT1B | golgi transport 1B | -0.0046145 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00460482 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00459652 |
| IL17RB | interleukin 17 receptor B | -0.00459469 |
| DLG5 | discs, large homolog 5 (Drosophila) | -0.00459069 |
| BCL2L1 | BCL2-like 1 | -0.00458883 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00458146 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00457975 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | -0.00456546 |
| LRRC17 | leucine rich repeat containing 17 | -0.00454826 |
| CHMP4A | charged multivesicular body protein 4A | -0.00453942 |
| CHMP6 | charged multivesicular body protein 6 | -0.00452707 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.00451795 |
| HSPA8 | heat shock 70kDa protein 8 | -0.00450448 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00449604 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.0044953 |
| TALDO1 | transaldolase 1 | -0.00448101 |
| BID | BH3 interacting domain death agonist | -0.00447915 |
| IL1RN | interleukin 1 receptor antagonist | -0.00446625 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00446394 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00446033 |
| TUBA4A | tubulin, alpha 4a | -0.00445533 |
| CHMP2A | charged multivesicular body protein 2A | -0.00445459 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00444029 |
| PEG3 | paternally expressed 3 | -0.00443846 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00443779 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.00443004 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.00442354 |
| S100A12 | S100 calcium binding protein A12 | -0.00442284 |
| PLIN3 | perilipin 3 | -0.00442058 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) | -0.00441944 |
| LONP2 | lon peptidase 2, peroxisomal | -0.00441623 |
| IL2RB | interleukin 2 receptor, beta | -0.00441034 |
| AZU1 | azurocidin 1 | -0.00440462 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.00440395 |
| TSPAN5 | tetraspanin 5 | -0.004401 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -0.00438388 |
| CAMP | cathelicidin antimicrobial peptide | -0.00437559 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00437355 |
| CRYM | crystallin, mu | -0.00437076 |
| CYB5R1 | cytochrome b5 reductase 1 | -0.00436978 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00435984 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00435961 |
| TMEM87A | transmembrane protein 87A | -0.00435908 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | -0.00435674 |
| HAT1 | histone acetyltransferase 1 | -0.00435293 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00435244 |
| NOSIP | nitric oxide synthase interacting protein | -0.00435029 |
| AHR | aryl hydrocarbon receptor | -0.00434331 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.00433474 |
| NUTF2 | nuclear transport factor 2 | -0.00432979 |
| RAB5IF | RAB5 interacting factor | -0.00432561 |
