IKBKG Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma|This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 8517)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_IKBKG
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Genes

135 co-expressed genes for IKBKG from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADAMTSL2 ADAMTS-like 2
AGER advanced glycosylation end product-specific receptor
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANKRD12 ankyrin repeat domain 12
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARSE arylsulfatase E (chondrodysplasia punctata 1)
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
BAHD1 bromo adjacent homology domain containing 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDC25C cell division cycle 25C
CIB1 calcium and integrin binding 1 (calmyrin)
CNOT4 CCR4-NOT transcription complex, subunit 4
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CNTN1 contactin 1
COPS6 COP9 signalosome subunit 6
CRCP CGRP receptor component
CRHR2 corticotropin releasing hormone receptor 2
CRYBA4 crystallin, beta A4
CSNK1D casein kinase 1, delta
CSNK2A1 casein kinase 2, alpha 1 polypeptide
DCAF7 DDB1 and CUL4 associated factor 7
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHRS1 dehydrogenase/reductase (SDR family) member 1
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DRG2 developmentally regulated GTP binding protein 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EML3 echinoderm microtubule associated protein like 3
FAM189A2 family with sequence similarity 189, member A2
FAM189B family with sequence similarity 189, member B
FANCG Fanconi anemia, complementation group G
FDXR ferredoxin reductase
FKBP15 FK506 binding protein 15, 133kDa
GHITM growth hormone inducible transmembrane protein
GPR35 G protein-coupled receptor 35
GRB2 growth factor receptor-bound protein 2
GRK6 G protein-coupled receptor kinase 6
GSK3A glycogen synthase kinase 3 alpha
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
HMG20B high mobility group 20B
HMGXB3 HMG box domain containing 3
HNRNPL heterogeneous nuclear ribonucleoprotein L
HSF4 heat shock transcription factor 4
IFT140 intraflagellar transport 140
IGHMBP2 immunoglobulin mu binding protein 2
IGSF9B immunoglobulin superfamily, member 9B
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
ILVBL ilvB (bacterial acetolactate synthase)-like
KDM3B lysine (K)-specific demethylase 3B
KHNYN KH and NYN domain containing
KIAA0195 KIAA0195
LDB1 LIM domain binding 1
LSM12 LSM12 homolog (S. cerevisiae)
M6PR mannose-6-phosphate receptor (cation dependent)
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCM3AP minichromosome maintenance complex component 3 associated protein
MCRS1 microspherule protein 1
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MMP25 matrix metallopeptidase 25
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MR1 major histocompatibility complex, class I-related
MTX1 metaxin 1
MVK mevalonate kinase
MYL2 myosin, light chain 2, regulatory, cardiac, slow
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NELFB negative elongation factor complex member B
NFRKB nuclear factor related to kappaB binding protein
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
ORC1 origin recognition complex, subunit 1
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PAIP2B poly(A) binding protein interacting protein 2B
PARN poly(A)-specific ribonuclease
PAX8 paired box 8
PCBP3 poly(rC) binding protein 3
PCGF1 polycomb group ring finger 1
PFDN1 prefoldin subunit 1
PHB prohibitin
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLIN3 perilipin 3
PMF1 polyamine-modulated factor 1
PML promyelocytic leukemia
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRKCSH protein kinase C substrate 80K-H
PRPH peripherin
PSD4 pleckstrin and Sec7 domain containing 4
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PVT1 Pvt1 oncogene (non-protein coding)
RABAC1 Rab acceptor 1 (prenylated)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RBM8A RNA binding motif protein 8A
RPA2 replication protein A2, 32kDa
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RXRB retinoid X receptor, beta
SCAMP5 secretory carrier membrane protein 5
SETD1B SET domain containing 1B
SFSWAP splicing factor, suppressor of white-apricot family
SH2B1 SH2B adaptor protein 1
SIK3 SIK family kinase 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A24 solute carrier family 22, member 24
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
TCOF1 Treacher Collins-Franceschetti syndrome 1
TPMT thiopurine S-methyltransferase
TRA2A transformer 2 alpha homolog (Drosophila)
TSPO2 translocator protein 2
TSTA3 tissue specific transplantation antigen P35B
TUB tubby bipartite transcription factor
TUBGCP2 tubulin, gamma complex associated protein 2
USP11 ubiquitin specific peptidase 11
USP19 ubiquitin specific peptidase 19
VAMP3 vesicle-associated membrane protein 3
WDR62 WD repeat domain 62
WWOX WW domain containing oxidoreductase
ZBED1 zinc finger, BED-type containing 1
ZFPL1 zinc finger protein-like 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF592 zinc finger protein 592