IKBKG Gene Set

Dataset NURSA Protein-Protein Interactions
Category proteomics
Type interacting protein
Description inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma|This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 8517)
External Link http://www.ncbi.nlm.nih.gov/gene/8517
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Genes

4 interacting proteins for IKBKG from the NURSA Protein-Protein Interactions dataset.

Symbol Name Standardized Value
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.675069
CHUK conserved helix-loop-helix ubiquitous kinase 0.589638
CDC37 cell division cycle 37 0.417402
FKBP5 FK506 binding protein 5 0.066687