IKKA Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description conserved helix-loop-helix ubiquitous kinase|This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1147)
Similar Terms
Downloads & Tools

Genes

100 substrates of the kinase IKKA from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
EIF5B eukaryotic translation initiation factor 5B
ARHGAP35 Rho GTPase activating protein 35
WTAP Wilms tumor 1 associated protein
C11ORF30 chromosome 11 open reading frame 30
CCDC88A coiled-coil domain containing 88A
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
AKAP13 A kinase (PRKA) anchor protein 13
SEPT4 septin 4
FNBP4 formin binding protein 4
TRPS1 trichorhinophalangeal syndrome I
CYLD cylindromatosis (turban tumor syndrome)
EIF5 eukaryotic translation initiation factor 5
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13
CENPH centromere protein H
CCDC138 coiled-coil domain containing 138
VCP valosin containing protein
CHD7 chromodomain helicase DNA binding protein 7
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
BRCA1 breast cancer 1, early onset
TJP1 tight junction protein 1
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
RBBP6 retinoblastoma binding protein 6
MIER3 mesoderm induction early response 1, family member 3
MCM3 minichromosome maintenance complex component 3
LRRC16A leucine rich repeat containing 16A
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
ZNF609 zinc finger protein 609
ZMYM3 zinc finger, MYM-type 3
HS1BP3 HCLS1 binding protein 3
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
YAP1 Yes-associated protein 1
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
HID1 HID1 domain containing
SAMD15 sterile alpha motif domain containing 15
NUCLEOLIN nucleolin multifunctional protein
DOT1L DOT1-like histone H3K79 methyltransferase
MIER1 mesoderm induction early response 1, transcriptional regulator
ERBB2IP erbb2 interacting protein
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
BCL10 B-cell CLL/lymphoma 10
HDGFRP3 hepatoma-derived growth factor, related protein 3
NUPL2 nucleoporin like 2
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PHLDB1 pleckstrin homology-like domain, family B, member 1
MKL2 MKL/myocardin-like 2
TCOF1 Treacher Collins-Franceschetti syndrome 1
SYNPO2 synaptopodin 2
ITGB4 integrin, beta 4
GOLGB1 golgin B1
STIM1 stromal interaction molecule 1
MAP2 microtubule-associated protein 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
FAM219B family with sequence similarity 219, member B
PHF8 PHD finger protein 8
WWC2 WW and C2 domain containing 2
BECN1 beclin 1, autophagy related
MAGED4B melanoma antigen family D4B
XIRP2 xin actin binding repeat containing 2
FANCM Fanconi anemia, complementation group M
RLF rearranged L-myc fusion
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
KDM1A lysine (K)-specific demethylase 1A
C12ORF4 chromosome 12 open reading frame 4
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
C8ORF37 chromosome 8 open reading frame 37
EDC4 enhancer of mRNA decapping 4
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
ERCC6 excision repair cross-complementation group 6
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
TRADD TNFRSF1A-associated via death domain
ERCC6L excision repair cross-complementation group 6-like
NFXL1 nuclear transcription factor, X-box binding-like 1
ANXA5 annexin A5
PSEN2 presenilin 2
SELENBP1 selenium binding protein 1
MSL1 male-specific lethal 1 homolog (Drosophila)
NOLC1 nucleolar and coiled-body phosphoprotein 1
AXIN1 axin 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
TRAF1 TNF receptor-associated factor 1
TRPM7 transient receptor potential cation channel, subfamily M, member 7
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
QSER1 glutamine and serine rich 1
RB1 retinoblastoma 1
SYNM synemin, intermediate filament protein
RAI1 retinoic acid induced 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CLK3 CDC-like kinase 3
PDCD11 programmed cell death 11
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
USO1 USO1 vesicle transport factor
NOP56 NOP56 ribonucleoprotein
CTNND1 catenin (cadherin-associated protein), delta 1
SDC1 syndecan 1