IKKB Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta|The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011] (NCBI Entrez Gene Database, 3551)
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Genes

100 substrates of the kinase IKKB from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
PSEN2 presenilin 2
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
NEB nebulin
NES nestin
APOBR apolipoprotein B receptor
KAT7 K(lysine) acetyltransferase 7
PCDH7 protocadherin 7
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
SCAF1 SR-related CTD-associated factor 1
CHD7 chromodomain helicase DNA binding protein 7
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
CTPS1 CTP synthase 1
NEFH neurofilament, heavy polypeptide
C16ORF59 chromosome 16 open reading frame 59
SDC1 syndecan 1
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
CENPF centromere protein F, 350/400kDa
PRDM2 PR domain containing 2, with ZNF domain
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
NBEAL2 neurobeachin-like 2
CCDC138 coiled-coil domain containing 138
THSD1 thrombospondin, type I, domain containing 1
CYLD cylindromatosis (turban tumor syndrome)
PRX periaxin
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
UIMC1 ubiquitin interaction motif containing 1
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
CEP131 centrosomal protein 131kDa
SAMD15 sterile alpha motif domain containing 15
LRRC16A leucine rich repeat containing 16A
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
SHROOM3 shroom family member 3
BLM Bloom syndrome, RecQ helicase-like
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
CKB creatine kinase, brain
FNTA farnesyltransferase, CAAX box, alpha
ERBB2IP erbb2 interacting protein
ARHGAP39 Rho GTPase activating protein 39
PACS2 phosphofurin acidic cluster sorting protein 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
RAB12 RAB12, member RAS oncogene family
JUNB jun B proto-oncogene
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
TNRC6B trinucleotide repeat containing 6B
CPPED1 calcineurin-like phosphoesterase domain containing 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
RC3H2 ring finger and CCCH-type domains 2
YAP1 Yes-associated protein 1
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
DOCK8 dedicator of cytokinesis 8
DCTN1 dynactin 1
ITGB4 integrin, beta 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
NCAPH2 non-SMC condensin II complex, subunit H2
PCM1 pericentriolar material 1
DSP desmoplakin
FAM219B family with sequence similarity 219, member B
ALMS1 Alstrom syndrome protein 1
RAB5A RAB5A, member RAS oncogene family
SYNPO2 synaptopodin 2
MAGED4B melanoma antigen family D4B
XIRP2 xin actin binding repeat containing 2
CDC37 cell division cycle 37
ACACB acetyl-CoA carboxylase beta
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
ABLIM3 actin binding LIM protein family, member 3
EDC4 enhancer of mRNA decapping 4
RAB27A RAB27A, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
ERCC6 excision repair cross-complementation group 6
FANCM Fanconi anemia, complementation group M
PRUNE2 prune homolog 2 (Drosophila)
LIMCH1 LIM and calponin homology domains 1
PARD3 par-3 family cell polarity regulator
LAD1 ladinin 1
CLK3 CDC-like kinase 3
FRS2 fibroblast growth factor receptor substrate 2
USP34 ubiquitin specific peptidase 34
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
CTNND1 catenin (cadherin-associated protein), delta 1
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
TRPM7 transient receptor potential cation channel, subfamily M, member 7
PPP1R12A protein phosphatase 1, regulatory subunit 12A
JMJD1C jumonji domain containing 1C
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
TBK1 TANK-binding kinase 1
DES desmin
HNRNPK heterogeneous nuclear ribonucleoprotein K
AHCTF1 AT hook containing transcription factor 1
JAK1 Janus kinase 1
CCAR2 cell cycle and apoptosis regulator 2
MAP3K11 mitogen-activated protein kinase kinase kinase 11
ZC3H13 zinc finger CCCH-type containing 13
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
NACAD NAC alpha domain containing
RAI1 retinoic acid induced 1
LMNB1 lamin B1
RAB7A RAB7A, member RAS oncogene family