IKZF1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description IKAROS family zinc finger 1 (Ikaros)|This gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. Most isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homo-dimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence, resulting in members with and without DNA-binding properties. Only a few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and are thought to function as dominant-negative factors. Overexpression of some dominant-negative isoforms have been associated with B-cell malignancies, such as acute lymphoblastic leukemia (ALL). [provided by RefSeq, May 2014] (NCBI Entrez Gene Database, 10320)
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Genes

389 genes differentially expressed following the IKZF1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 4.31737
SLC26A4 solute carrier family 26 (anion exchanger), member 4 4.31737
PROX2 prospero homeobox 2 4.31737
WDR64 WD repeat domain 64 4.31737
DHRS7C dehydrogenase/reductase (SDR family) member 7C 4.31737
CTXN2 cortexin 2 4.31737
SUN3 Sad1 and UNC84 domain containing 3 4.31737
CAPS calcyphosine 4.31737
ANKRD63 ankyrin repeat domain 63 4.31737
TDRD10 tudor domain containing 10 4.31737
C17ORF99 chromosome 17 open reading frame 99 4.31737
TEX38 testis expressed 38 4.31737
MYH13 myosin, heavy chain 13, skeletal muscle 4.31737
CD19 CD19 molecule 4.31737
TREH trehalase (brush-border membrane glycoprotein) 4.31737
LHX2 LIM homeobox 2 4.31737
COX8C cytochrome c oxidase subunit VIIIC 4.31737
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 4.31737
PON1 paraoxonase 1 4.31737
GREP1 glycine rich extracellular protein 1 4.31737
LAMB3 laminin, beta 3 4.31737
CATSPERZ catsper channel auxiliary subunit zeta 4.31737
GAB3 GRB2-associated binding protein 3 4.31737
IGFBP7 insulin-like growth factor binding protein 7 4.31737
DCT dopachrome tautomerase 4.31737
PAX6 paired box 6 4.31737
EPHB3 EPH receptor B3 4.31737
XCL1 chemokine (C motif) ligand 1 4.23779
GLUD2 glutamate dehydrogenase 2 4.23779
TNNI1 troponin I type 1 (skeletal, slow) 4.23779
F7 coagulation factor VII (serum prothrombin conversion accelerator) 4.23779
NUGGC nuclear GTPase, germinal center associated 4.23779
RGPD4 RANBP2-like and GRIP domain containing 4 4.23779
TRPV6 transient receptor potential cation channel, subfamily V, member 6 4.23779
UBA7 ubiquitin-like modifier activating enzyme 7 4.23779
OR2J2 olfactory receptor, family 2, subfamily J, member 2 4.23779
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 4.23779
GFAP glial fibrillary acidic protein 4.23779
SP7 Sp7 transcription factor 4.23779
FOLR3 folate receptor 3 (gamma) 4.23779
SMIM5 small integral membrane protein 5 4.23779
CD68 CD68 molecule 4.23779
STEAP4 STEAP family member 4 4.23779
NWD1 NACHT and WD repeat domain containing 1 4.23779
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 4.23779
CCDC87 coiled-coil domain containing 87 4.23779
TWIST1 twist family bHLH transcription factor 1 4.23779
CTAG2 cancer/testis antigen 2 4.23779
NPR3 natriuretic peptide receptor 3 4.23779
G6PC2 glucose-6-phosphatase, catalytic, 2 4.23779
ANXA2R annexin A2 receptor 4.23779
CD33 CD33 molecule 4.23779
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 4.23779
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 4.23779
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 4.23779
CLEC5A C-type lectin domain family 5, member A 4.23779
TRIM42 tripartite motif containing 42 4.23779
ADAT3 adenosine deaminase, tRNA-specific 3 4.23779
TMEM121 transmembrane protein 121 4.23779
IL2RB interleukin 2 receptor, beta 4.23779
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 4.23779
MPL MPL proto-oncogene, thrombopoietin receptor 4.23779
MYO1G myosin IG 4.23779
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 4.23779
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 4.23779
PITX3 paired-like homeodomain 3 4.23779
NOTCH2NLB notch 2 N-terminal like B 4.23779
TMPRSS7 transmembrane protease, serine 7 4.23779
TTR transthyretin 4.23779
ZNF441 zinc finger protein 441 4.23779
GATA2 GATA binding protein 2 4.23779
PNPLA1 patatin-like phospholipase domain containing 1 4.23779
DRC5 dynein regulatory complex subunit 5 4.23779
LRRC73 leucine rich repeat containing 73 4.23779
OOSP1 oocyte secreted protein 1, pseudogene 4.23779
RGS21 regulator of G-protein signaling 21 4.23779
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 4.23779
C1QTNF9B C1q and tumor necrosis factor related protein 9B 4.23779
HBG2 hemoglobin, gamma G 4.23779
ZNF593OS ZNF593 opposite strand 4.23779
SMIM45 small integral membrane protein 45 4.23779
CFAP299 cilia and flagella associated protein 299 4.23779
GSTT4 glutathione S-transferase theta 4 4.23779
TMEM275 transmembrane protein 275 4.23779
FYB1 FYN binding protein 1 4.23779
SQOR sulfide quinone oxidoreductase 4.23779
DEFB108B defensin, beta 108B 4.23779
GIPC3 GIPC PDZ domain containing family, member 3 4.23779
TCF23 transcription factor 23 4.23779
PIWIL1 piwi-like RNA-mediated gene silencing 1 4.23779
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 4.23779
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 4.23779
NXPE4 neurexophilin and PC-esterase domain family, member 4 4.23779
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 4.23779
SPINK4 serine peptidase inhibitor, Kazal type 4 4.23779
PRICKLE4 prickle homolog 4 (Drosophila) 4.23779
NANOS2 nanos homolog 2 (Drosophila) 4.23779
PGAM4 phosphoglycerate mutase family member 4 4.23779
FGL2 fibrinogen-like 2 4.23779
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 4.23779
UCN urocortin 4.23779
CFHR3 complement factor H-related 3 4.23779
PIWIL3 piwi-like RNA-mediated gene silencing 3 4.23779
TMEM236 transmembrane protein 236 4.23779
AMHR2 anti-Mullerian hormone receptor, type II 4.23779
DSG1 desmoglein 1 4.23779
TEX101 testis expressed 101 4.23779
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 4.23779
RAB44 RAB44, member RAS oncogene family 4.23779
PVRIG poliovirus receptor related immunoglobulin domain containing 4.23779
OSTN osteocrin 4.23779
DNASE1L2 deoxyribonuclease I-like 2 4.23779
EMX2 empty spiracles homeobox 2 4.23779
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 4.23779
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 4.23779
PLA2G4D phospholipase A2, group IVD (cytosolic) 4.23779
DMRT1 doublesex and mab-3 related transcription factor 1 4.23779
FCN3 ficolin (collagen/fibrinogen domain containing) 3 4.23779
MAGED4B melanoma antigen family D4B 4.23779
TSPYL6 TSPY-like 6 4.23779
DMTN dematin actin binding protein 4.23779
TCAP titin-cap 4.23779
NUTM2A NUT family member 2A 4.23779
ADGRF5 adhesion G protein-coupled receptor F5 4.23779
POU4F1 POU class 4 homeobox 1 4.23779
GPR142 G protein-coupled receptor 142 4.23779
SLITRK6 SLIT and NTRK-like family, member 6 4.23779
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 4.23779
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 4.23779
PTHLH parathyroid hormone-like hormone 4.23779
NIPAL4 NIPA-like domain containing 4 4.23779
CTAGE9 CTAGE family, member 9 4.23779
CD244 CD244 molecule, natural killer cell receptor 2B4 4.23779
BTNL8 butyrophilin-like 8 4.23779
POF1B premature ovarian failure, 1B 4.23779
CST5 cystatin D 4.23779
TRIM55 tripartite motif containing 55 4.23779
KRT3 keratin 3, type II 4.23779
SAMD7 sterile alpha motif domain containing 7 4.23779
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 4.23779
GLYATL3 glycine-N-acyltransferase-like 3 4.23779
EBF2 early B-cell factor 2 4.23779
A3GALT2 alpha 1,3-galactosyltransferase 2 4.23779
PCDHGB5 protocadherin gamma subfamily B, 5 4.23779
PCDHGB4 protocadherin gamma subfamily B, 4 4.23779
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 4.23779
CLCA2 chloride channel accessory 2 4.23779
CLCA1 chloride channel accessory 1 4.23779
CASQ2 calsequestrin 2 (cardiac muscle) 4.23779
RNF148 ring finger protein 148 4.23779
OR52I2 olfactory receptor, family 52, subfamily I, member 2 4.23779
ADAM18 ADAM metallopeptidase domain 18 4.23779
KRTAP1-1 keratin associated protein 1-1 4.23779
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 4.23779
GOLGA8T golgin A8 family, member T 4.23779
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 4.23779
RP1 retinitis pigmentosa 1 (autosomal dominant) 4.23779
MMP12 matrix metallopeptidase 12 4.23779
MMP19 matrix metallopeptidase 19 4.23779
ADGRA1 adhesion G protein-coupled receptor A1 4.23779
ASCL1 achaete-scute family bHLH transcription factor 1 4.23779
IL10RA interleukin 10 receptor, alpha 4.23779
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 4.23779
PRAP1 proline-rich acidic protein 1 4.23779
SLC51B solute carrier family 51, beta subunit 4.23779
KRT34 keratin 34, type I 4.23779
DMRTC1 DMRT-like family C1 4.23779
TAS2R46 taste receptor, type 2, member 46 4.23779
CFH complement factor H 4.23779
DMRTC2 DMRT-like family C2 4.23779
KCNK15 potassium channel, two pore domain subfamily K, member 15 4.23779
CLEC2A C-type lectin domain family 2, member A 4.23779
MEIOB meiosis specific with OB domains 4.23184
SLC49A3 solute carrier family 49 member 3 4.23184
CD70 CD70 molecule 4.23184
SERTM1 serine-rich and transmembrane domain containing 1 4.23184
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 4.23184
FOSL2 FOS-like antigen 2 3.79166
SCD5 stearoyl-CoA desaturase 5 3.79166
C1ORF202 chromosome 1 open reading frame 202 3.50979
PGF placental growth factor 3.46471
POC5 POC5 centriolar protein 3.26334
SYPL2 synaptophysin-like 2 3.23212
TMEM88 transmembrane protein 88 3.23212
ANKRD61 ankyrin repeat domain 61 3.23212
TRIM72 tripartite motif containing 72, E3 ubiquitin protein ligase 3.23212
GFY golgi-associated, olfactory signaling regulator 3.23212
LRRC66 leucine rich repeat containing 66 3.23212
ATRAID all-trans retinoic acid-induced differentiation factor 3.07347
GNS glucosamine (N-acetyl)-6-sulfatase 3.07128
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 3.05764
BMP3 bone morphogenetic protein 3 3.05764
KCMF1 potassium channel modulatory factor 1 2.9895
ZNF557 zinc finger protein 557 2.90757
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 2.89351
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 2.89351
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 2.84514
NR1D2 nuclear receptor subfamily 1, group D, member 2 2.80013
SLC35H1 solute carrier family 35 member H1 2.74013
IGSF23 immunoglobulin superfamily, member 23 2.73347
ZNF396 zinc finger protein 396 2.73347
EHD1 EH-domain containing 1 2.71317
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 2.698
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 2.67642
COL7A1 collagen, type VII, alpha 1 2.64604
NDN necdin, melanoma antigen (MAGE) family member 2.62645
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 2.56507
SNAP29 synaptosomal-associated protein, 29kDa 2.53098
PDPK1 3-phosphoinositide dependent protein kinase 1 2.49984
ELAC1 elaC ribonuclease Z 1 2.49984
INTS1 integrator complex subunit 1 2.42579
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 2.41449
LIPT1 lipoyltransferase 1 2.40965
SLC67A2 solute carrier family 67 member 2 2.40965
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 2.40965
RGPD2 RANBP2-like and GRIP domain containing 2 2.39389
ERBB4 erb-b2 receptor tyrosine kinase 4 2.39249
PCDHB6 protocadherin beta 6 2.38547
TM9SF3 transmembrane 9 superfamily member 3 2.37909
TXNL4A thioredoxin-like 4A 2.371
BAZ1B bromodomain adjacent to zinc finger domain, 1B 2.35474
AXIN2 axin 2 2.33143
ZMIZ1 zinc finger, MIZ-type containing 1 2.32565
TMEM59L transmembrane protein 59-like 2.32134
CYCS cytochrome c, somatic 2.30743
CYS1 cystin 1 2.29762
RRAS2 related RAS viral (r-ras) oncogene homolog 2 2.29762
FGF4 fibroblast growth factor 4 2.29762
CCDC93 coiled-coil domain containing 93 2.29684
KIAA0319 KIAA0319 2.29684
BZW1 basic leucine zipper and W2 domains 1 2.28372
MYO5A myosin VA (heavy chain 12, myoxin) 2.26998
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 2.268
FAM114A2 family with sequence similarity 114, member A2 2.25764
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 2.25764
LRP10 low density lipoprotein receptor-related protein 10 2.25574
KDM3A lysine (K)-specific demethylase 3A 2.24625
FMNL1 formin-like 1 2.24528
TBL2 transducin (beta)-like 2 2.23945
JMJD7 jumonji domain containing 7 2.23945
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.23671
TMEM234 transmembrane protein 234 2.23169
PHKB phosphorylase kinase, beta 2.22932
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 2.2276
NBR1 neighbor of BRCA1 gene 1 2.2276
SLITRK4 SLIT and NTRK-like family, member 4 2.21571
RHOT1 ras homolog family member T1 2.1848
LRRC40 leucine rich repeat containing 40 2.16077
PID1 phosphotyrosine interaction domain containing 1 2.15585
ZDHHC3 zinc finger, DHHC-type containing 3 2.15155
NCOA3 nuclear receptor coactivator 3 2.15155
DNAH14 dynein, axonemal, heavy chain 14 2.1475
PPT2 palmitoyl-protein thioesterase 2 2.13222
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 2.12673
H2BC11 H2B clustered histone 11 2.12219
SEC63 SEC63 homolog (S. cerevisiae) 2.12204
CWF19L2 CWF19-like 2, cell cycle control (S. pombe) 2.10655
SIAH3 siah E3 ubiquitin protein ligase family member 3 2.10655
LRP3 low density lipoprotein receptor-related protein 3 2.10408
DBN1 drebrin 1 2.07176
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.07176
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 2.07125
ETFB electron-transfer-flavoprotein, beta polypeptide 2.07125
LMOD1 leiomodin 1 (smooth muscle) 2.06783
NCKAP5 NCK-associated protein 5 2.06337
SIK3 SIK family kinase 3 2.06035
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.05382
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 2.02128
SMCO2 single-pass membrane protein with coiled-coil domains 2 2.00895
ARHGAP21 Rho GTPase activating protein 21 2.00462

decreased expression

Symbol Name Standardized Value
FBXO48 F-box protein 48 -4.31737
DACT3 dishevelled-binding antagonist of beta-catenin 3 -4.31737
RNF222 ring finger protein 222 -4.31737
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) -4.31737
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 -4.31737
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -4.31737
ELOVL2 ELOVL fatty acid elongase 2 -4.31737
ZNF792 zinc finger protein 792 -4.23779
FETUB fetuin B -4.23184
FAM167A family with sequence similarity 167, member A -4.23184
GNLY granulysin -4.23184
NXPH3 neurexophilin 3 -4.23184
GNRHR gonadotropin-releasing hormone receptor -4.23184
MYCT1 myc target 1 -4.23184
CARD9 caspase recruitment domain family, member 9 -4.23184
DPPA3 developmental pluripotency associated 3 -4.23184
PRDM16 PR domain containing 16 -4.23184
LRRC38 leucine rich repeat containing 38 -4.23184
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 -4.23184
PARP15 poly (ADP-ribose) polymerase family, member 15 -4.23184
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 -4.23184
CORO6 coronin 6 -4.23184
SPEGNB SPEG neighbor -4.23184
MAMDC4 MAM domain containing 4 -4.23184
TMEM40 transmembrane protein 40 -4.23184
ASB9 ankyrin repeat and SOCS box containing 9 -4.23184
FAM107A family with sequence similarity 107, member A -4.23184
TMPPE transmembrane protein with metallophosphoesterase domain -4.23184
KRT86 keratin 86, type II -4.23184
TMEM31 transmembrane protein 31 -4.23184
MGAM maltase-glucoamylase -4.23184
PLA2G2C phospholipase A2, group IIC -4.23184
CRYBB3 crystallin, beta B3 -4.23184
CLRN1 clarin 1 -4.23184
SAXO4 stabilizer of axonemal microtubules 4 -4.23184
MAG myelin associated glycoprotein -4.23184
CKM creatine kinase, muscle -4.23184
OXTR oxytocin receptor -4.15681
CFAP43 cilia and flagella associated protein 43 -3.82873
CNMD chondromodulin -3.26334
FAM228B family with sequence similarity 228, member B -3.12115
GOLPH3 golgi phosphoprotein 3 (coat-protein) -3.11663
RGPD1 RANBP2-like and GRIP domain containing 1 -3.07347
LDHD lactate dehydrogenase D -3.07347
ACRBP acrosin binding protein -3.07347
STAR steroidogenic acute regulatory protein -3.07347
GSDMA gasdermin A -3.07347
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 -3.07347
DCST2 DC-STAMP domain containing 2 -3.07347
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 -3.07347
BHLHA15 basic helix-loop-helix family, member a15 -3.07347
SLA2 Src-like-adaptor 2 -3.07347
TMF1 TATA element modulatory factor 1 -3.01132
CA13 carbonic anhydrase XIII -2.98287
IGFBP5 insulin-like growth factor binding protein 5 -2.97011
SYCP3 synaptonemal complex protein 3 -2.90757
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -2.79745
AMN1 antagonist of mitotic exit network 1 homolog (S. cerevisiae) -2.79308
CIB1 calcium and integrin binding 1 (calmyrin) -2.74202
ANAPC1 anaphase promoting complex subunit 1 -2.71317
SPATA24 spermatogenesis associated 24 -2.61227
SRRD SRR1 domain containing -2.58989
NCR1 natural cytotoxicity triggering receptor 1 -2.58396
TTYH2 tweety family member 2 -2.58396
APLP2 amyloid beta (A4) precursor-like protein 2 -2.5838
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -2.54444
PMEL premelanosome protein -2.49984
LAG3 lymphocyte-activation gene 3 -2.4826
CDK12 cyclin-dependent kinase 12 -2.47206
JUNB jun B proto-oncogene -2.40965
RETREG3 reticulophagy regulator family member 3 -2.371
TUBA8 tubulin, alpha 8 -2.35208
OXCT2 3-oxoacid CoA transferase 2 -2.35208
EDF1 endothelial differentiation-related factor 1 -2.35203
LRRC3B leucine rich repeat containing 3B -2.33485
IRAK1 interleukin-1 receptor-associated kinase 1 -2.30743
ZNF443 zinc finger protein 443 -2.29762
GJB7 gap junction protein, beta 7, 25kDa -2.29762
SLA Src-like-adaptor -2.29046
C16ORF95 chromosome 16 open reading frame 95 -2.2889
TMEM272 transmembrane protein 272 -2.2889
OMG oligodendrocyte myelin glycoprotein -2.2867
TMEM191C transmembrane protein 191C -2.25574
TCF15 transcription factor 15 (basic helix-loop-helix) -2.23945
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -2.23945
CSPG4 chondroitin sulfate proteoglycan 4 -2.23343
ZNF586 zinc finger protein 586 -2.2319
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) -2.23169
TCP11L2 t-complex 11, testis-specific-like 2 -2.23169
CRY2 cryptochrome circadian clock 2 -2.20728
RING1 ring finger protein 1 -2.20262
LRRN2 leucine rich repeat neuronal 2 -2.18949
ARRB2 arrestin, beta 2 -2.16669
ZNF189 zinc finger protein 189 -2.15936
TMEM115 transmembrane protein 115 -2.13714
TBC1D20 TBC1 domain family, member 20 -2.13652
C19ORF81 chromosome 19 open reading frame 81 -2.13222
TMEM154 transmembrane protein 154 -2.13222
DENND5B DENN/MADD domain containing 5B -2.12904
SCARB2 scavenger receptor class B, member 2 -2.12689
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) -2.11859
SSBP1 single-stranded DNA binding protein 1, mitochondrial -2.10448
RFX5 regulatory factor X, 5 (influences HLA class II expression) -2.10448
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 -2.08453
TP53RK TP53 regulating kinase -2.08311
ZNF732 zinc finger protein 732 -2.08169
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 -2.07323
INTS8 integrator complex subunit 8 -2.07224
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.07221
NAMPT nicotinamide phosphoribosyltransferase -2.06178
CCNL2 cyclin L2 -2.05589
CAPN12 calpain 12 -2.05522
NAIF1 nuclear apoptosis inducing factor 1 -2.05382
PEX16 peroxisomal biogenesis factor 16 -2.04158
C1ORF167 chromosome 1 open reading frame 167 -2.04076
MORN3 MORN repeat containing 3 -2.04076
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 -2.04076
CMTR2 cap methyltransferase 2 -2.04076
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G -2.0376