| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | IKAROS family zinc finger 3 (Aiolos)|This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012] (NCBI Entrez Gene Database, 22806) |
| External Link | https://ncbi.nlm.nih.gov/gene/22806 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the IKZF3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | 0.0141043 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.014048 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0139867 |
| ANXA3 | annexin A3 | 0.0132183 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.0130762 |
| STOM | stomatin | 0.0129784 |
| S100P | S100 calcium binding protein P | 0.012623 |
| RND3 | Rho family GTPase 3 | 0.0120203 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0119847 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0116516 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0112465 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0111907 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0109614 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0106601 |
| S100A12 | S100 calcium binding protein A12 | 0.0106256 |
| CTSS | cathepsin S | 0.0102552 |
| TPD52L1 | tumor protein D52-like 1 | 0.0101877 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.0101625 |
| TPSAB1 | tryptase alpha/beta 1 | 0.0101554 |
| IFI44L | interferon-induced protein 44-like | 0.0100665 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0100351 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00975613 |
| ATF3 | activating transcription factor 3 | 0.00974322 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0096573 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00957173 |
| ANXA1 | annexin A1 | 0.00951464 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00943356 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0093657 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00936282 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00928379 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00922136 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00892296 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0086873 |
| CA2 | carbonic anhydrase II | 0.00868293 |
| NPC2 | Niemann-Pick disease, type C2 | 0.00867688 |
| JUNB | jun B proto-oncogene | 0.00867153 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00865606 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00862875 |
| POU4F1 | POU class 4 homeobox 1 | 0.00857793 |
| TRIM22 | tripartite motif containing 22 | 0.0085678 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00854113 |
| GSAP | gamma-secretase activating protein | 0.00852672 |
| XIC | X chromosome inactivation center | 0.00852579 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00842205 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00835783 |
| CTSB | cathepsin B | 0.00833418 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00824836 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00814472 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.0081434 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00810383 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00807584 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00805942 |
| CD38 | CD38 molecule | 0.00804839 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00798685 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00797963 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.00793751 |
| CHMP5 | charged multivesicular body protein 5 | 0.00788449 |
| MYOF | myoferlin | 0.00787378 |
| ACP3 | acid phosphatase 3 | 0.00785285 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00780632 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00779852 |
| CFB | complement factor B | 0.00775103 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00768363 |
| TGM2 | transglutaminase 2 | 0.00765709 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | 0.00762876 |
| NMB | neuromedin B | 0.0076205 |
| MMP9 | matrix metallopeptidase 9 | 0.00761166 |
| IRS2 | insulin receptor substrate 2 | 0.00761129 |
| MALL | mal, T-cell differentiation protein-like | 0.00757434 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00755924 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00755916 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00755026 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00751028 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00746469 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00745339 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.0074388 |
| MYO1C | myosin IC | 0.00742165 |
| OPTN | optineurin | 0.00741793 |
| LUM | lumican | 0.00741498 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00738114 |
| LXN | latexin | 0.00731609 |
| NMD3 | NMD3 ribosome export adaptor | 0.00730672 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.007241 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00720222 |
| TPD52 | tumor protein D52 | 0.0071846 |
| PLTP | phospholipid transfer protein | 0.00718124 |
| GPX1 | glutathione peroxidase 1 | 0.00716635 |
| PSAP | prosaposin | 0.00713159 |
| SCEL | sciellin | 0.00708996 |
| LBH | limb bud and heart development | 0.00707002 |
| CST7 | cystatin F (leukocystatin) | 0.00704969 |
| S100A8 | S100 calcium binding protein A8 | 0.00704819 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00704275 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.00703888 |
| PLBD1 | phospholipase B domain containing 1 | 0.0070147 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 0.00700958 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0069831 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00696197 |
| ITGA6 | integrin, alpha 6 | 0.00695286 |
| CANX | calnexin | 0.00693891 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00693326 |
| C1S | complement component 1, s subcomponent | 0.00692382 |
| TWF1 | twinfilin actin binding protein 1 | 0.00692148 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0069094 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00688704 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.0068532 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00685127 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00684499 |
| TMEM106B | transmembrane protein 106B | 0.00682924 |
| COMMD3 | COMM domain containing 3 | 0.00677458 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) | 0.00676958 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00675694 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00674737 |
| PERP | PERP, TP53 apoptosis effector | 0.00672288 |
| ATP9A | ATPase, class II, type 9A | 0.00670987 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00669509 |
| MCL1 | myeloid cell leukemia 1 | 0.00668518 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.0066827 |
| RBM34 | RNA binding motif protein 34 | 0.00667041 |
| PCNA | proliferating cell nuclear antigen | 0.00665488 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00661345 |
| IFI30 | interferon, gamma-inducible protein 30 | 0.00660703 |
| EGR1 | early growth response 1 | 0.0065829 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00657626 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 0.00657516 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0065597 |
| ACOT13 | acyl-CoA thioesterase 13 | 0.0065009 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00647002 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00645202 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00644934 |
| IFRD1 | interferon-related developmental regulator 1 | 0.00641206 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.0064112 |
| ENAH | enabled homolog (Drosophila) | 0.00639735 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00639504 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00638362 |
| MECOM | MDS1 and EVI1 complex locus | 0.00637327 |
| PTCH1 | patched 1 | 0.00635795 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00635592 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00634424 |
| DUSP5 | dual specificity phosphatase 5 | 0.00633917 |
| IL32 | interleukin 32 | 0.00633523 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00632511 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00631866 |
| LCN2 | lipocalin 2 | 0.00631366 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00631176 |
| PON2 | paraoxonase 2 | 0.00629144 |
| BUD31 | BUD31 homolog (S. cerevisiae) | 0.00627721 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00627232 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00626895 |
| C11ORF58 | chromosome 11 open reading frame 58 | 0.00626655 |
| ZNF394 | zinc finger protein 394 | 0.00625189 |
| HECA | headcase homolog (Drosophila) | 0.006249 |
| RCAN1 | regulator of calcineurin 1 | 0.00624803 |
| GPM6B | glycoprotein M6B | 0.00622814 |
| S100A9 | S100 calcium binding protein A9 | 0.00621491 |
| MAT2B | methionine adenosyltransferase II, beta | 0.00621329 |
| SQSTM1 | sequestosome 1 | 0.00620703 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.00619276 |
| TGFB3 | transforming growth factor, beta 3 | 0.00617578 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0061672 |
| PDCD10 | programmed cell death 10 | 0.00616194 |
| CLC | Charcot-Leyden crystal galectin | 0.0061602 |
| IRF1 | interferon regulatory factor 1 | 0.00613511 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00612288 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00609818 |
| CAV2 | caveolin 2 | 0.00609737 |
| HIST1H2BH | histone cluster 1, H2bh | 0.00607822 |
| EMP1 | epithelial membrane protein 1 | 0.00607407 |
| NRN1 | neuritin 1 | 0.00603476 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.0060045 |
| CNN3 | calponin 3, acidic | 0.00599791 |
| PRPF4 | pre-mRNA processing factor 4 | 0.0059545 |
| CLEC5A | C-type lectin domain family 5, member A | 0.00594552 |
| LY96 | lymphocyte antigen 96 | 0.00594049 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00592886 |
| PKP1 | plakophilin 1 | 0.00589315 |
| CDCA4 | cell division cycle associated 4 | 0.00587186 |
| CTSK | cathepsin K | 0.00586229 |
| CCNA1 | cyclin A1 | 0.00585882 |
| CD52 | CD52 molecule | 0.00585279 |
| FYB1 | FYN binding protein 1 | 0.00584425 |
| PRAME | preferentially expressed antigen in melanoma | 0.00584341 |
| AIM2 | absent in melanoma 2 | 0.00584053 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00581443 |
| CDC37L1 | cell division cycle 37-like 1 | 0.00580266 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00579551 |
| APOL2 | apolipoprotein L, 2 | 0.00578746 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00578125 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0057757 |
| TMEM9B | TMEM9 domain family, member B | 0.00576381 |
| CLIC4 | chloride intracellular channel 4 | 0.00575183 |
| IL7R | interleukin 7 receptor | 0.00573417 |
| FZD5 | frizzled class receptor 5 | 0.00572737 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00571422 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00570657 |
| NOL8 | nucleolar protein 8 | 0.00570438 |
| CORO1C | coronin, actin binding protein, 1C | 0.00570244 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00570039 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00569277 |
| SERINC1 | serine incorporator 1 | 0.00568988 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00568564 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa | 0.00568228 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.0056748 |
| APOL1 | apolipoprotein L, 1 | 0.00566862 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00566516 |
| CDK14 | cyclin-dependent kinase 14 | 0.00565832 |
| COCH | cochlin | 0.00564142 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00564111 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00563689 |
| SIRT3 | sirtuin 3 | 0.00563401 |
| SULF1 | sulfatase 1 | 0.00562662 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein | 0.00561429 |
| IFI35 | interferon-induced protein 35 | 0.00560244 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00558305 |
| LAMC2 | laminin, gamma 2 | 0.00557877 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.00557748 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00557647 |
| IPO7 | importin 7 | 0.00555176 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 | 0.00554665 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00554398 |
| FBLN1 | fibulin 1 | 0.00554338 |
| PRKCB | protein kinase C, beta | 0.00552864 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00552664 |
| MFSD1 | major facilitator superfamily domain containing 1 | 0.00550858 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00550387 |
| UXS1 | UDP-glucuronate decarboxylase 1 | 0.00549738 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0054758 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00547263 |
| JAG1 | jagged 1 | 0.00547015 |
| NUP58 | nucleoporin 58 | 0.00546944 |
| RPA2 | replication protein A2, 32kDa | 0.0054488 |
| UNC50 | unc-50 homolog (C. elegans) | 0.00544516 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | 0.00543159 |
| ARMC1 | armadillo repeat containing 1 | 0.00543004 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.00542558 |
| BTG2 | BTG family, member 2 | 0.0054158 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.00541264 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing | 0.0054062 |
| S100A4 | S100 calcium binding protein A4 | 0.00540067 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.00539851 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00539703 |
| MMP8 | matrix metallopeptidase 8 | 0.00539589 |
| EGR3 | early growth response 3 | 0.00538986 |
| PTGES | prostaglandin E synthase | 0.00538906 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00537348 |
| PAGE4 | P antigen family, member 4 (prostate associated) | 0.00536524 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | 0.00536055 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00535872 |
| TP63 | tumor protein p63 | 0.00535628 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0158892 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0155555 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.0138603 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.0127439 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0116718 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.011248 |
| TCTA | T-cell leukemia translocation altered | -0.0110019 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0108568 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0107718 |
| PDZK1 | PDZ domain containing 1 | -0.0102913 |
| COL9A3 | collagen, type IX, alpha 3 | -0.010231 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0101629 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0101108 |
| CLDN10 | claudin 10 | -0.0100933 |
| PROM1 | prominin 1 | -0.00992866 |
| CDC20 | cell division cycle 20 | -0.00984662 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00963308 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00960679 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00954974 |
| TUBA1A | tubulin, alpha 1a | -0.00950522 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00937024 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00928995 |
| MMP1 | matrix metallopeptidase 1 | -0.00904078 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.00896425 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00895656 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00886845 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00872624 |
| NTS | neurotensin | -0.00871173 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00868837 |
| PEG3 | paternally expressed 3 | -0.00853658 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00849346 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00844262 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00836803 |
| XYLT1 | xylosyltransferase I | -0.00829731 |
| COL3A1 | collagen, type III, alpha 1 | -0.00825166 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00824472 |
| KRT18 | keratin 18, type I | -0.00823767 |
| PLIN2 | perilipin 2 | -0.00822839 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00822832 |
| FASN | fatty acid synthase | -0.00822705 |
| METTL7A | methyltransferase like 7A | -0.00818732 |
| CLU | clusterin | -0.00810821 |
| LOXL1 | lysyl oxidase-like 1 | -0.00804062 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00802934 |
| PMP22 | peripheral myelin protein 22 | -0.00802522 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00802106 |
| NLGN4X | neuroligin 4, X-linked | -0.00796856 |
| MGLL | monoglyceride lipase | -0.00793979 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.0078764 |
| ASRGL1 | asparaginase like 1 | -0.00784404 |
| MATN2 | matrilin 2 | -0.00783122 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00772882 |
| AURKB | aurora kinase B | -0.00772376 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00767947 |
| NFASC | neurofascin | -0.00767195 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00763356 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00762855 |
| HOXC6 | homeobox C6 | -0.00759002 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00754428 |
| KRT19 | keratin 19, type I | -0.00749518 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0074683 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00743743 |
| HMGB3 | high mobility group box 3 | -0.00741511 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.0073947 |
| MEN1 | multiple endocrine neoplasia I | -0.00738624 |
| OLFM1 | olfactomedin 1 | -0.0073743 |
| CHGB | chromogranin B | -0.00733212 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0073009 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00724913 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.00724708 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00721647 |
| TMSB15A | thymosin beta 15a | -0.00716351 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00715683 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00713175 |
| BEX1 | brain expressed, X-linked 1 | -0.0071315 |
| IL17RB | interleukin 17 receptor B | -0.00710599 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | -0.00704827 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00700973 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00700855 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00700568 |
| COLEC11 | collectin sub-family member 11 | -0.00698513 |
| PDGFD | platelet derived growth factor D | -0.00696886 |
| RAPSN | receptor-associated protein of the synapse | -0.00696517 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00695837 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00692775 |
| TWF2 | twinfilin actin binding protein 2 | -0.00691573 |
| FIBP | fibroblast growth factor (acidic) intracellular binding protein | -0.00690226 |
| HIP1 | huntingtin interacting protein 1 | -0.00690094 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00686418 |
| FZD2 | frizzled class receptor 2 | -0.00684354 |
| NID1 | nidogen 1 | -0.00683939 |
| SDC2 | syndecan 2 | -0.00683423 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00682971 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.00682472 |
| IRX5 | iroquois homeobox 5 | -0.00681742 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.0068105 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | -0.006764 |
| DGKZ | diacylglycerol kinase, zeta | -0.00674931 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.00668322 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00666241 |
| FADS1 | fatty acid desaturase 1 | -0.00665185 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0066411 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00656305 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.0065552 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00655064 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.00654991 |
| NYNRIN | NYN domain and retroviral integrase containing | -0.00654811 |
| RTN2 | reticulon 2 | -0.00654198 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00652395 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | -0.00648015 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00647448 |
| PXDN | peroxidasin | -0.00645709 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00644333 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00642447 |
| STK10 | serine/threonine kinase 10 | -0.00641631 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.0063545 |
| KCTD14 | potassium channel tetramerization domain containing 14 | -0.00634961 |
| ZW10 | zw10 kinetochore protein | -0.00634429 |
| WDTC1 | WD and tetratricopeptide repeats 1 | -0.00633652 |
| TSPAN12 | tetraspanin 12 | -0.0063002 |
| GAS1 | growth arrest-specific 1 | -0.00628448 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.00627676 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00625285 |
| THBS2 | thrombospondin 2 | -0.00624678 |
| WT1 | Wilms tumor 1 | -0.00620151 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00618571 |
| USP22 | ubiquitin specific peptidase 22 | -0.00618029 |
| RGS5 | regulator of G-protein signaling 5 | -0.0061664 |
| TFF1 | trefoil factor 1 | -0.006135 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00612031 |
| KLHDC8A | kelch domain containing 8A | -0.00611036 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00608763 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00606388 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00605529 |
| CCL21 | chemokine (C-C motif) ligand 21 | -0.00604561 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -0.006044 |
| PLLP | plasmolipin | -0.00603364 |
| MACROH2A1 | macroH2A.1 histone | -0.00603051 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00600646 |
| MAGED1 | melanoma antigen family D1 | -0.00595438 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.00594837 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00594248 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.00594015 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.0059203 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.00591755 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00586211 |
| MEIS1 | Meis homeobox 1 | -0.00583488 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.00583196 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00580077 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00579968 |
| LMNB2 | lamin B2 | -0.0057956 |
| DZIP1 | DAZ interacting zinc finger protein 1 | -0.00578468 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00578006 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00577445 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.0057676 |
| FAAP100 | FA core complex associated protein 100 | -0.00576398 |
| SCGN | secretagogin, EF-hand calcium binding protein | -0.00575653 |
| GUCY2C | guanylate cyclase 2C | -0.00574071 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.00574012 |
| DCPS | decapping enzyme, scavenger | -0.00573567 |
| SEPTIN9 | septin 9 | -0.00572102 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00571839 |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 | -0.00571426 |
| INSM1 | insulinoma-associated 1 | -0.00571326 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00569774 |
| PODXL | podocalyxin-like | -0.0056798 |
| TP53 | tumor protein p53 | -0.00566482 |
| PIPOX | pipecolic acid oxidase | -0.00563892 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -0.00563786 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | -0.0056377 |
| KAZN | kazrin, periplakin interacting protein | -0.00563276 |
| HYOU1 | hypoxia up-regulated 1 | -0.00561255 |
| CHN2 | chimerin 2 | -0.00561248 |
| RET | ret proto-oncogene | -0.00559198 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00558955 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.00558698 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00558334 |
| POGLUT2 | protein O-glucosyltransferase 2 | -0.00557831 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | -0.00555824 |
| DAP | death-associated protein | -0.0055543 |
| VNN1 | vanin 1 | -0.00555029 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00554909 |
| SNX7 | sorting nexin 7 | -0.00554385 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -0.00552981 |
| LAMB1 | laminin, beta 1 | -0.00552593 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00552575 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00551894 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00551078 |
| OXTR | oxytocin receptor | -0.00550285 |
| ACD | adrenocortical dysplasia homolog (mouse) | -0.00549634 |
| ALB | albumin | -0.00548079 |
| MTA1 | metastasis associated 1 | -0.00548014 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 | -0.00547547 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | -0.00545301 |
| LPIN1 | lipin 1 | -0.00544561 |
| LSP1 | lymphocyte-specific protein 1 | -0.00544158 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00542895 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit | -0.00542815 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00542142 |
| GCG | glucagon | -0.00541009 |
| LOC730101 | uncharacterized LOC730101 | -0.00536529 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00535239 |
| SIVA1 | SIVA1, apoptosis-inducing factor | -0.00535232 |
| EFHD2 | EF-hand domain family, member D2 | -0.00535073 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00534806 |
| CSK | c-src tyrosine kinase | -0.00533674 |
| HEATR1 | HEAT repeat containing 1 | -0.0053363 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | -0.00532438 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -0.00530562 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00528825 |
| SIX2 | SIX homeobox 2 | -0.00527393 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00526393 |
| LRRC49 | leucine rich repeat containing 49 | -0.00525922 |
| ABHD2 | abhydrolase domain containing 2 | -0.00523011 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00522636 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.00521995 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00521029 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00520699 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00520557 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -0.00520443 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0051926 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00518436 |
| PLXNB2 | plexin B2 | -0.00518374 |
| P3H1 | prolyl 3-hydroxylase 1 | -0.00518215 |
| FCGBP | Fc fragment of IgG binding protein | -0.00518029 |
| AACS | acetoacetyl-CoA synthetase | -0.00516798 |
| CARD10 | caspase recruitment domain family, member 10 | -0.00516441 |
| AMH | anti-Mullerian hormone | -0.00516396 |
| GUSB | glucuronidase, beta | -0.00516031 |
| REG1B | regenerating islet-derived 1 beta | -0.00515974 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | -0.00513092 |
| HOMER3 | homer scaffolding protein 3 | -0.00512384 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.00511679 |
| ENO1 | enolase 1, (alpha) | -0.00509996 |
| H2AX | H2A.X variant histone | -0.00509564 |
| PIMREG | PICALM interacting mitotic regulator | -0.00509029 |
| WRAP53 | WD repeat containing, antisense to TP53 | -0.00508926 |
| SALL2 | spalt-like transcription factor 2 | -0.00508801 |
| FSTL1 | follistatin-like 1 | -0.00507428 |
| FAM193A | family with sequence similarity 193, member A | -0.00507299 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.0050708 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00505113 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.0050326 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00503094 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.00502386 |
| GPR183 | G protein-coupled receptor 183 | -0.00502364 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | -0.00501561 |
| NUP210 | nucleoporin 210kDa | -0.00499214 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00499179 |
| TK1 | thymidine kinase 1, soluble | -0.00498774 |
