IL-6 signaling pathway(Homo sapiens) Gene Set

Dataset WikiPathways Pathways 2014
Category structural or functional annotations
Type pathway
External Link http://www.wikipathways.org/instance/WP364_r83783
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Genes

43 proteins participating in the IL-6 signaling pathway(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

Symbol Name
A2M alpha-2-macroglobulin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1 v-akt murine thymoma viral oncogene homolog 1
BAD BCL2-associated agonist of cell death
BCL2L1 BCL2-like 1
CREBBP CREB binding protein
CRP C-reactive protein, pentraxin-related
GAB1 GRB2-associated binding protein 1
GRB2 growth factor receptor-bound protein 2
GSK3B glycogen synthase kinase 3 beta
HCK HCK proto-oncogene, Src family tyrosine kinase
HDAC1 histone deacetylase 1
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IRF1 interferon regulatory factor 1
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUNB jun B proto-oncogene
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
NCOA1 nuclear receptor coactivator 1
NLK nemo-like kinase
NR2F6 nuclear receptor subfamily 2, group F, member 6
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PRDM1 PR domain containing 1, with ZNF domain
PRKCD protein kinase C, delta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOCS3 suppressor of cytokine signaling 3
SOS1 son of sevenless homolog 1 (Drosophila)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TIMP1 TIMP metallopeptidase inhibitor 1
TYK2 tyrosine kinase 2
VAV1 vav 1 guanine nucleotide exchange factor
VIP vasoactive intestinal peptide