IL12-mediated signaling events Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/7acdea19-6193-11e5-8ac5-06603eb7f303
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Genes

61 proteins participating in the IL12-mediated signaling events pathway from the PID Pathways dataset.

Symbol Name
ATF2 activating transcription factor 2
B2M beta-2-microglobulin
CCL3 chemokine (C-C motif) ligand 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD247 CD247 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD8A CD8a molecule
CD8B CD8b molecule
EOMES eomesodermin
FASLG Fas ligand (TNF superfamily, member 6)
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HLA-A major histocompatibility complex, class I, A
HLA-DRA major histocompatibility complex, class II, DR alpha
HLX H2.0-like homeobox
IFNG interferon, gamma
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL18RAP interleukin 18 receptor accessory protein
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL4 interleukin 4
JAK2 Janus kinase 2
LCK LCK proto-oncogene, Src family tyrosine kinase
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK14 mitogen-activated protein kinase 14
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOS2 nitric oxide synthase 2, inducible
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
RAB7A RAB7A, member RAS oncogene family
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIPK2 receptor-interacting serine-threonine kinase 2
SOCS1 suppressor of cytokine signaling 1
SPHK2 sphingosine kinase 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TBX21 T-box 21
TYK2 tyrosine kinase 2