| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | interleukin 12A|This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3592) |
| External Link | https://ncbi.nlm.nih.gov/gene/3592 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the IL12A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | 0.0250375 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.0224587 |
| S100A8 | S100 calcium binding protein A8 | 0.0182101 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.0163044 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0161029 |
| S100P | S100 calcium binding protein P | 0.0151483 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.0136755 |
| CSTA | cystatin A (stefin A) | 0.0136624 |
| S100A9 | S100 calcium binding protein A9 | 0.0135683 |
| FABP7 | fatty acid binding protein 7, brain | 0.0131647 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0129458 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0127796 |
| CLDN10 | claudin 10 | 0.0125839 |
| CD48 | CD48 molecule | 0.0125812 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0123284 |
| ADD3 | adducin 3 (gamma) | 0.01211 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.0120129 |
| LCN2 | lipocalin 2 | 0.0118647 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.011806 |
| CETN2 | centrin, EF-hand protein, 2 | 0.011692 |
| KRT19 | keratin 19, type I | 0.0116479 |
| PADI2 | peptidyl arginine deiminase, type II | 0.011413 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.0111196 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0111113 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.0110978 |
| S100A7 | S100 calcium binding protein A7 | 0.0110805 |
| PITX3 | paired-like homeodomain 3 | 0.0109505 |
| FASN | fatty acid synthase | 0.0108718 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0107923 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.01077 |
| FOXC1 | forkhead box C1 | 0.0106812 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0105382 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.0103878 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.0103372 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.0101194 |
| DGKZ | diacylglycerol kinase, zeta | 0.0100728 |
| MSMB | microseminoprotein, beta- | 0.0100365 |
| ABHD10 | abhydrolase domain containing 10 | 0.00991761 |
| PODXL | podocalyxin-like | 0.00990966 |
| MSLN | mesothelin | 0.00986131 |
| CEP70 | centrosomal protein 70kDa | 0.00980226 |
| PLPBP | pyridoxal phosphate binding protein | 0.00975381 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00974897 |
| KRT13 | keratin 13, type I | 0.00972714 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00971932 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | 0.00966471 |
| KRT15 | keratin 15, type I | 0.00966292 |
| SDC1 | syndecan 1 | 0.0095312 |
| H1-2 | H1.2 linker histone, cluster member | 0.00950492 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00929501 |
| CALML5 | calmodulin-like 5 | 0.00926167 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00925683 |
| MRPS10 | mitochondrial ribosomal protein S10 | 0.00921124 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.00915388 |
| IFT52 | intraflagellar transport 52 | 0.00915192 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00911662 |
| PRKCQ | protein kinase C, theta | 0.00904132 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.0090366 |
| BPI | bactericidal/permeability-increasing protein | 0.0090172 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00901522 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00899324 |
| EFHD1 | EF-hand domain family, member D1 | 0.00898916 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.0089343 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00888511 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00886748 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00882752 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00880612 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00876225 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.0087179 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00869001 |
| HAT1 | histone acetyltransferase 1 | 0.00868216 |
| EMX2 | empty spiracles homeobox 2 | 0.00867495 |
| COPS4 | COP9 signalosome subunit 4 | 0.00864459 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00861117 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00857267 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00852884 |
| CAMP | cathelicidin antimicrobial peptide | 0.00851605 |
| PROM1 | prominin 1 | 0.0084598 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.0084597 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00844557 |
| IL2RG | interleukin 2 receptor, gamma | 0.00842361 |
| MUC4 | mucin 4, cell surface associated | 0.00837135 |
| GTPBP8 | GTP-binding protein 8 (putative) | 0.00833985 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00831174 |
| MEIS2 | Meis homeobox 2 | 0.00826698 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00826054 |
| ENOPH1 | enolase-phosphatase 1 | 0.00823245 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.00821655 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00819996 |
| NEBL | nebulette | 0.00817372 |
| COG7 | component of oligomeric golgi complex 7 | 0.00816594 |
| EAF2 | ELL associated factor 2 | 0.00816465 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00815991 |
| BSPRY | B-box and SPRY domain containing | 0.00815923 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | 0.00814366 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 0.00812677 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00812595 |
| HMGA1 | high mobility group AT-hook 1 | 0.00809118 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00802198 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00795073 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.00793343 |
| TEX30 | testis expressed 30 | 0.00789401 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.00779068 |
| FZD6 | frizzled class receptor 6 | 0.00771008 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.00769659 |
| WDR61 | WD repeat domain 61 | 0.00769413 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.00769392 |
| RAB25 | RAB25, member RAS oncogene family | 0.00760618 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00758889 |
| GCH1 | GTP cyclohydrolase 1 | 0.00755912 |
| CCNF | cyclin F | 0.00755467 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00755304 |
| BIN2 | bridging integrator 2 | 0.00753543 |
| SOSTDC1 | sclerostin domain containing 1 | 0.00752054 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00751666 |
| KLHDC3 | kelch domain containing 3 | 0.00751482 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00750899 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00750316 |
| UMOD | uromodulin | 0.00748539 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 0.00746877 |
| NEK4 | NIMA-related kinase 4 | 0.00745582 |
| RANBP9 | RAN binding protein 9 | 0.00745063 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.00743366 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00742548 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00735934 |
| SUSD4 | sushi domain containing 4 | 0.00735318 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00734639 |
| MUC16 | mucin 16, cell surface associated | 0.00733154 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00731406 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.0072958 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.00727459 |
| FAM46C | family with sequence similarity 46, member C | 0.00726765 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00724703 |
| ANKRD46 | ankyrin repeat domain 46 | 0.00720418 |
| PAK1IP1 | PAK1 interacting protein 1 | 0.00719815 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00715459 |
| CCDC176 | coiled-coil domain containing 176 | 0.007154 |
| RAB4A | RAB4A, member RAS oncogene family | 0.00714804 |
| MLF1 | myeloid leukemia factor 1 | 0.00712837 |
| NXT1 | nuclear transport factor 2-like export factor 1 | 0.00711717 |
| CCNA2 | cyclin A2 | 0.0071074 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00708836 |
| RPS5 | ribosomal protein S5 | 0.0070624 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00705456 |
| KLK6 | kallikrein-related peptidase 6 | 0.00702415 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00702313 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00700014 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.00699257 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00698847 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00697385 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | 0.00695399 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00695064 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00693854 |
| PLBD1 | phospholipase B domain containing 1 | 0.00687931 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00685955 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00684957 |
| SORT1 | sortilin 1 | 0.00684319 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00683864 |
| SPAG4 | sperm associated antigen 4 | 0.00683816 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00683801 |
| RGS10 | regulator of G-protein signaling 10 | 0.00683165 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00682647 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00681928 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | 0.0067839 |
| EAPP | E2F-associated phosphoprotein | 0.00677346 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00677044 |
| MPO | myeloperoxidase | 0.00675232 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00674977 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00674631 |
| TERT | telomerase reverse transcriptase | 0.00674621 |
| CA9 | carbonic anhydrase IX | 0.00674053 |
| S100A12 | S100 calcium binding protein A12 | 0.00672952 |
| CD2 | CD2 molecule | 0.00672025 |
| NTAQ1 | N-terminal glutamine amidase 1 | 0.00670737 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00669079 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.00668074 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.0066791 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.0066775 |
| C9ORF40 | chromosome 9 open reading frame 40 | 0.0066713 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00666871 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00666024 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.00664306 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.00663977 |
| CLEC7A | C-type lectin domain family 7, member A | 0.00662078 |
| SV2A | synaptic vesicle glycoprotein 2A | 0.0066032 |
| MAT2B | methionine adenosyltransferase II, beta | 0.00659962 |
| TJP2 | tight junction protein 2 | 0.00659406 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00657139 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | 0.00654864 |
| FAIM | Fas apoptotic inhibitory molecule | 0.00654711 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | 0.00653137 |
| RPA3 | replication protein A3, 14kDa | 0.00652965 |
| NUP210 | nucleoporin 210kDa | 0.00651769 |
| H1-10 | H1.10 linker histone | 0.00651467 |
| CLDN7 | claudin 7 | 0.00650114 |
| MUC1 | mucin 1, cell surface associated | 0.00649986 |
| FLOT2 | flotillin 2 | 0.00648566 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.00647403 |
| RAD51 | RAD51 recombinase | 0.00646868 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00646721 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00644255 |
| GAMT | guanidinoacetate N-methyltransferase | 0.00643336 |
| CD177 | CD177 molecule | 0.0064308 |
| KAZN | kazrin, periplakin interacting protein | 0.0064244 |
| ZFAND1 | zinc finger, AN1-type domain 1 | 0.00640825 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00639215 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.00638218 |
| RMI1 | RecQ mediated genome instability 1 | 0.00638123 |
| NPAS2 | neuronal PAS domain protein 2 | 0.00637043 |
| NDUFA9 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 0.00636672 |
| LZTFL1 | leucine zipper transcription factor-like 1 | 0.0063598 |
| MICB | MHC class I polypeptide-related sequence B | 0.00635806 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | 0.00633259 |
| CRIPT | cysteine-rich PDZ-binding protein | 0.00632619 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00631935 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 0.00629777 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) | 0.00629657 |
| TEAD4 | TEA domain family member 4 | 0.00629538 |
| GLTP | glycolipid transfer protein | 0.00628828 |
| EVI2A | ecotropic viral integration site 2A | 0.00628239 |
| KRT5 | keratin 5, type II | 0.00626837 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 0.00626514 |
| SEH1L | SEH1-like (S. cerevisiae) | 0.00625965 |
| TMEM38B | transmembrane protein 38B | 0.00625601 |
| COMMD8 | COMM domain containing 8 | 0.00624954 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) | 0.00623909 |
| NVL | nuclear VCP-like | 0.00623518 |
| THBS1 | thrombospondin 1 | 0.00622001 |
| SH3GL3 | SH3-domain GRB2-like 3 | 0.00621443 |
| FAM234B | family with sequence similarity 234 member B | 0.00621442 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00620831 |
| AAGAB | alpha- and gamma-adaptin binding protein | 0.00620419 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00620378 |
| HPF1 | histone PARylation factor 1 | 0.00619937 |
| TMEM45A | transmembrane protein 45A | 0.00619254 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00619117 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | 0.00618393 |
| DCK | deoxycytidine kinase | 0.00616219 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0061461 |
| PITX1 | paired-like homeodomain 1 | 0.00614126 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | 0.00613349 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00612158 |
| ANO10 | anoctamin 10 | 0.00611793 |
| TBXA2R | thromboxane A2 receptor | 0.00608971 |
| NPR3 | natriuretic peptide receptor 3 | 0.00608919 |
| CEL | carboxyl ester lipase | 0.00608752 |
| LIPT1 | lipoyltransferase 1 | 0.00604276 |
| TMEM14A | transmembrane protein 14A | 0.00602845 |
| IRF6 | interferon regulatory factor 6 | 0.00602525 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00599921 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | -0.0218972 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0192525 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0182114 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0172363 |
| EGR1 | early growth response 1 | -0.0154212 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0149707 |
| MX1 | MX dynamin-like GTPase 1 | -0.0141553 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.0133676 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.0132559 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0131751 |
| FOXO1 | forkhead box O1 | -0.0130764 |
| PDGFD | platelet derived growth factor D | -0.0128538 |
| GOLGA8A | golgin A8 family, member A | -0.0127672 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0127005 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0125309 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0124675 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0124147 |
| IFI44L | interferon-induced protein 44-like | -0.0121396 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0118579 |
| CTSZ | cathepsin Z | -0.0118548 |
| RGS5 | regulator of G-protein signaling 5 | -0.0117907 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.011624 |
| AREG | amphiregulin | -0.0115979 |
| TNS3 | tensin 3 | -0.0113839 |
| PCP4 | Purkinje cell protein 4 | -0.0112899 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0111735 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0111512 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0111465 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.011128 |
| MT1X | metallothionein 1X | -0.0110018 |
| GLA | galactosidase, alpha | -0.0105009 |
| EFNB2 | ephrin-B2 | -0.0103721 |
| NPY | neuropeptide Y | -0.0103708 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0103365 |
| CPM | carboxypeptidase M | -0.0103164 |
| PEG10 | paternally expressed 10 | -0.0101837 |
| NKX2-1 | NK2 homeobox 1 | -0.0101216 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0101122 |
| MSX1 | msh homeobox 1 | -0.0100178 |
| BMP2 | bone morphogenetic protein 2 | -0.0100062 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.009879 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00986474 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | -0.00977324 |
| COL4A2 | collagen, type IV, alpha 2 | -0.00976993 |
| MT1E | metallothionein 1E | -0.00974027 |
| MMP3 | matrix metallopeptidase 3 | -0.00970235 |
| EDNRB | endothelin receptor type B | -0.00969574 |
| PLVAP | plasmalemma vesicle associated protein | -0.00969357 |
| CADM1 | cell adhesion molecule 1 | -0.00962858 |
| TAC1 | tachykinin, precursor 1 | -0.00961601 |
| ASS1 | argininosuccinate synthase 1 | -0.0095343 |
| LOXL2 | lysyl oxidase-like 2 | -0.00950009 |
| FN1 | fibronectin 1 | -0.00944081 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00943319 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00926995 |
| VWF | von Willebrand factor | -0.00925029 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00922398 |
| CTSL | cathepsin L | -0.00917213 |
| MT1H | metallothionein 1H | -0.00916788 |
| TBX3 | T-box 3 | -0.00916332 |
| PXDN | peroxidasin | -0.00915023 |
| CCN3 | cellular communication network factor 3 | -0.00912588 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00908455 |
| STC2 | stanniocalcin 2 | -0.00907031 |
| RGS16 | regulator of G-protein signaling 16 | -0.00905716 |
| DCLK1 | doublecortin-like kinase 1 | -0.0090451 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00903144 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00895536 |
| NEFH | neurofilament, heavy polypeptide | -0.00895468 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00893293 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00889583 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0088497 |
| BRD4 | bromodomain containing 4 | -0.00880366 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00875721 |
| SPAG9 | sperm associated antigen 9 | -0.00875449 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0087404 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00873437 |
| NID2 | nidogen 2 (osteonidogen) | -0.00870015 |
| GAB2 | GRB2-associated binding protein 2 | -0.00869369 |
| CHGB | chromogranin B | -0.00867833 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00867598 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00861472 |
| STK17A | serine/threonine kinase 17a | -0.00861136 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00859327 |
| RTN4 | reticulon 4 | -0.00855922 |
| AIM2 | absent in melanoma 2 | -0.00855413 |
| STC1 | stanniocalcin 1 | -0.0085402 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0085014 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00846217 |
| RBM47 | RNA binding motif protein 47 | -0.00845311 |
| SETBP1 | SET binding protein 1 | -0.00843944 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.00843028 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00842869 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.00841918 |
| IGF1R | insulin-like growth factor 1 receptor | -0.00837595 |
| THBS4 | thrombospondin 4 | -0.0083488 |
| GRN | granulin | -0.00834165 |
| MT1G | metallothionein 1G | -0.00833337 |
| TSPAN7 | tetraspanin 7 | -0.00831453 |
| HMOX1 | heme oxygenase 1 | -0.00830747 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00830606 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00827075 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00826282 |
| ZNF160 | zinc finger protein 160 | -0.00822914 |
| ADI1 | acireductone dioxygenase 1 | -0.00821952 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.00819903 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0081863 |
| EGR3 | early growth response 3 | -0.00818514 |
| CUX1 | cut-like homeobox 1 | -0.00818398 |
| PAX5 | paired box 5 | -0.00816315 |
| GLS | glutaminase | -0.00816161 |
| SC5D | sterol-C5-desaturase | -0.00816069 |
| CCNB1 | cyclin B1 | -0.00815524 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00814765 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00814051 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.00812948 |
| TCF4 | transcription factor 4 | -0.00812006 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00811858 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00811472 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00809965 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00807416 |
| IRS1 | insulin receptor substrate 1 | -0.00805508 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00802011 |
| FMOD | fibromodulin | -0.00800748 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.0079796 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00795519 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00794108 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.00792474 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00790321 |
| KDR | kinase insert domain receptor | -0.00790064 |
| MAOA | monoamine oxidase A | -0.00789548 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.0078639 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.00784271 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.00784269 |
| CLDN5 | claudin 5 | -0.00781619 |
| SIRT3 | sirtuin 3 | -0.0078136 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00780509 |
| CD93 | CD93 molecule | -0.00780269 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00779144 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00777429 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -0.00776041 |
| ANGPT2 | angiopoietin 2 | -0.00775651 |
| FSTL1 | follistatin-like 1 | -0.00774032 |
| SV2C | synaptic vesicle glycoprotein 2C | -0.00771135 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00770821 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00770495 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.0076893 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00768502 |
| COMP | cartilage oligomeric matrix protein | -0.00768098 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00762633 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00762357 |
| TUBA4A | tubulin, alpha 4a | -0.0076049 |
| TXNRD1 | thioredoxin reductase 1 | -0.00759892 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00759018 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00754057 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00753707 |
| ESYT1 | extended synaptotagmin-like protein 1 | -0.00751429 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00748748 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.00747783 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | -0.00746868 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.00746842 |
| NAV2 | neuron navigator 2 | -0.00745607 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00744829 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.00744193 |
| HLA-B | major histocompatibility complex, class I, B | -0.00744088 |
| WDR45 | WD repeat domain 45 | -0.00742425 |
| MT1M | metallothionein 1M | -0.00740284 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00739299 |
| ATP5ME | ATP synthase membrane subunit e | -0.00738269 |
| ADCY9 | adenylate cyclase 9 | -0.00736286 |
| INHBB | inhibin, beta B | -0.00735948 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00730078 |
| TRIM44 | tripartite motif containing 44 | -0.00729872 |
| RGS13 | regulator of G-protein signaling 13 | -0.00726084 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | -0.00725655 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00724353 |
| SFTPB | surfactant protein B | -0.00724294 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00724153 |
| USP47 | ubiquitin specific peptidase 47 | -0.00723284 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00723061 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00721287 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.00721058 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -0.00720353 |
| INSR | insulin receptor | -0.0072023 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0072 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00717163 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.00714148 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00713656 |
| MNT | MAX network transcriptional repressor | -0.00712884 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00712161 |
| PCDH17 | protocadherin 17 | -0.00711765 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00710025 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00709991 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.00709834 |
| BCHE | butyrylcholinesterase | -0.00709632 |
| KMT5B | lysine methyltransferase 5B | -0.00709349 |
| REG3A | regenerating islet-derived 3 alpha | -0.00708253 |
| CD99 | CD99 molecule | -0.00707364 |
| MGLL | monoglyceride lipase | -0.00706343 |
| MAEA | macrophage erythroblast attacher | -0.00705514 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00704965 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00704789 |
| PUM1 | pumilio RNA-binding family member 1 | -0.00702984 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.00702493 |
| SCG5 | secretogranin V | -0.00700187 |
| VEGFA | vascular endothelial growth factor A | -0.00699939 |
| PLCB4 | phospholipase C, beta 4 | -0.00698142 |
| MYO1B | myosin IB | -0.00697941 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | -0.00697242 |
| MCAM | melanoma cell adhesion molecule | -0.00697202 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.00696846 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0069677 |
| ENAH | enabled homolog (Drosophila) | -0.00696573 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 | -0.00692183 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | -0.00692147 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00688862 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00688213 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00687061 |
| NEFM | neurofilament, medium polypeptide | -0.00685708 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0068281 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00679576 |
| EREG | epiregulin | -0.00678743 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00678146 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.00678073 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.00677866 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -0.00676983 |
| USP6NL | USP6 N-terminal like | -0.00676317 |
| PLXNC1 | plexin C1 | -0.00674769 |
| PIGG | phosphatidylinositol glycan anchor biosynthesis, class G | -0.00674714 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.00672738 |
| MT1HL1 | metallothionein 1H-like 1 | -0.0067269 |
| ASPH | aspartate beta-hydroxylase | -0.00672586 |
| COL11A1 | collagen, type XI, alpha 1 | -0.006716 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.00670216 |
| PDLIM4 | PDZ and LIM domain 4 | -0.00670145 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.00668332 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.00667995 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00667804 |
| S100A4 | S100 calcium binding protein A4 | -0.0066772 |
| HEPH | hephaestin | -0.00667278 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0066619 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.00665238 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00665145 |
| RBM26 | RNA binding motif protein 26 | -0.00662868 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00662516 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.00661438 |
| OLFML2B | olfactomedin-like 2B | -0.00660714 |
| RASGRP3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) | -0.00660098 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.00658798 |
