IL13 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description interleukin 13|This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3596)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_IL13
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Genes

233 co-expressed genes for IL13 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACACB acetyl-CoA carboxylase beta
ADCY3 adenylate cyclase 3
AFF2 AF4/FMR2 family, member 2
AGPS alkylglycerone phosphate synthase
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
AOC4P amine oxidase, copper containing 4, pseudogene
AQP5 aquaporin 5
AQP7 aquaporin 7
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARL3 ADP-ribosylation factor-like 3
ASB4 ankyrin repeat and SOCS box containing 4
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATRX alpha thalassemia/mental retardation syndrome X-linked
BAHD1 bromo adjacent homology domain containing 1
BCL2 B-cell CLL/lymphoma 2
BMP10 bone morphogenetic protein 10
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BRCA1 breast cancer 1, early onset
BRD1 bromodomain containing 1
C10ORF12 chromosome 10 open reading frame 12
C1ORF216 chromosome 1 open reading frame 216
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCKAR cholecystokinin A receptor
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD6 CD6 molecule
CDC73 cell division cycle 73
CDYL chromodomain protein, Y-like
CELA2B chymotrypsin-like elastase family, member 2B
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CMA1 chymase 1, mast cell
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COL19A1 collagen, type XIX, alpha 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRHR1 corticotropin releasing hormone receptor 1
CTRL chymotrypsin-like
CXCR3 chemokine (C-X-C motif) receptor 3
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DKK4 dickkopf WNT signaling pathway inhibitor 4
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DOCK1 dedicator of cytokinesis 1
DPT dermatopontin
DTX4 deltex 4, E3 ubiquitin ligase
ECE1 endothelin converting enzyme 1
ECE2 endothelin converting enzyme 2
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPHB2 EPH receptor B2
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERCC4 excision repair cross-complementation group 4
ESR1 estrogen receptor 1
EXTL3 exostosin-like glycosyltransferase 3
FAM189A2 family with sequence similarity 189, member A2
FIG4 FIG4 phosphoinositide 5-phosphatase
FLJ16124
FLT1 fms-related tyrosine kinase 1
FNTB farnesyltransferase, CAAX box, beta
FOSL1 FOS-like antigen 1
FPR2 formyl peptide receptor 2
FRYL FRY-like
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GJB5 gap junction protein, beta 5, 31.1kDa
GLE1 GLE1 RNA export mediator
GNPAT glyceronephosphate O-acyltransferase
GPATCH8 G patch domain containing 8
GPR15 G protein-coupled receptor 15
GPR18 G protein-coupled receptor 18
GPR19 G protein-coupled receptor 19
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
GTSE1 G-2 and S-phase expressed 1
HCRT hypocretin (orexin) neuropeptide precursor
HNF1A HNF1 homeobox A
HOXA11 homeobox A11
HOXD13 homeobox D13
HOXD4 homeobox D4
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFT27 intraflagellar transport 27
IGKV7-3 immunoglobulin kappa variable 7-3 (pseudogene)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL11RA interleukin 11 receptor, alpha
IL13 interleukin 13
IL16 interleukin 16
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF2 interferon regulatory factor 2
IRS2 insulin receptor substrate 2
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
IVL involucrin
JAG1 jagged 1
JRK Jrk homolog (mouse)
KANK2 KN motif and ankyrin repeat domains 2
KANK3 KN motif and ankyrin repeat domains 3
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KIAA0195 KIAA0195
KIAA0586 KIAA0586
KLHL18 kelch-like family member 18
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT2 keratin 2, type II
KRT33A keratin 33A, type I
KRT86 keratin 86, type II
LBP lipopolysaccharide binding protein
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC48 leucine rich repeat containing 48
LTBP4 latent transforming growth factor beta binding protein 4
LY9 lymphocyte antigen 9
MAGEA9 melanoma antigen family A9
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MC5R melanocortin 5 receptor
MFN1 mitofusin 1
MSH3 mutS homolog 3
MSL3 male-specific lethal 3 homolog (Drosophila)
MSX1 msh homeobox 1
MT4 metallothionein 4
MYOZ3 myozenin 3
NCKIPSD NCK interacting protein with SH3 domain
NF1 neurofibromin 1
NOS2 nitric oxide synthase 2, inducible
NPFF neuropeptide FF-amide peptide precursor
NPHP4 nephronophthisis 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRP2 neuropilin 2
NRTN neurturin
NRXN1 neurexin 1
OPRL1 opiate receptor-like 1
OSBP oxysterol binding protein
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PARVB parvin, beta
PAX9 paired box 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PDE4A phosphodiesterase 4A, cAMP-specific
PGM3 phosphoglucomutase 3
PHF10 PHD finger protein 10
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGR polymeric immunoglobulin receptor
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POFUT2 protein O-fucosyltransferase 2
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POU6F1 POU class 6 homeobox 1
POU6F2 POU class 6 homeobox 2
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSG1 pregnancy specific beta-1-glycoprotein 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PVR poliovirus receptor
RAD51D RAD51 paralog D
RAP1A RAP1A, member of RAS oncogene family
RAP2C RAP2C, member of RAS oncogene family
RBBP8 retinoblastoma binding protein 8
RREB1 ras responsive element binding protein 1
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RXRG retinoid X receptor, gamma
S100A5 S100 calcium binding protein A5
SCAMP1 secretory carrier membrane protein 1
SCAPER S-phase cyclin A-associated protein in the ER
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SEZ6L seizure related 6 homolog (mouse)-like
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SGPL1 sphingosine-1-phosphate lyase 1
SIM2 single-minded family bHLH transcription factor 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SPEF1 sperm flagellar 1
SSTR5 somatostatin receptor 5
STK17A serine/threonine kinase 17a
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SULT4A1 sulfotransferase family 4A, member 1
SYNJ2 synaptojanin 2
SYT5 synaptotagmin V
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D22A TBC1 domain family, member 22A
TBX19 T-box 19
TBX5 T-box 5
TENM4 teneurin transmembrane protein 4
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TJP1 tight junction protein 1
TMEM11 transmembrane protein 11
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNIK TRAF2 and NCK interacting kinase
TSSK2 testis-specific serine kinase 2
TUBGCP4 tubulin, gamma complex associated protein 4
UBE4B ubiquitination factor E4B
UPK1A uroplakin 1A
UTRN utrophin
WBP4 WW domain binding protein 4
WDR62 WD repeat domain 62
ZBTB14 zinc finger and BTB domain containing 14
ZBTB22 zinc finger and BTB domain containing 22
ZBTB40 zinc finger and BTB domain containing 40
ZNF133 zinc finger protein 133
ZNF134 zinc finger protein 134
ZNF157 zinc finger protein 157
ZNF200 zinc finger protein 200
ZNF266 zinc finger protein 266
ZNF292 zinc finger protein 292
ZNF500 zinc finger protein 500
ZNF592 zinc finger protein 592
ZNF710 zinc finger protein 710
ZP2 zona pellucida glycoprotein 2 (sperm receptor)