IL16 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description interleukin 16|The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] (NCBI Entrez Gene Database, 3603)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_IL16
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Genes

241 co-expressed genes for IL16 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADAM20 ADAM metallopeptidase domain 20
ADAMTSL3 ADAMTS-like 3
ADCY3 adenylate cyclase 3
AFF2 AF4/FMR2 family, member 2
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
AMOT angiomotin
AOC4P amine oxidase, copper containing 4, pseudogene
AQP7 aquaporin 7
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARL3 ADP-ribosylation factor-like 3
ASB4 ankyrin repeat and SOCS box containing 4
ATF2 activating transcription factor 2
ATP10B ATPase, class V, type 10B
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN3 ataxin 3
BARX2 BARX homeobox 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BICD1 bicaudal D homolog 1 (Drosophila)
BMP10 bone morphogenetic protein 10
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BRCA1 breast cancer 1, early onset
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C1ORF216 chromosome 1 open reading frame 216
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CADM4 cell adhesion molecule 4
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL16 chemokine (C-C motif) ligand 16
CCR3 chemokine (C-C motif) receptor 3
CDC73 cell division cycle 73
CDYL chromodomain protein, Y-like
CELA2B chymotrypsin-like elastase family, member 2B
CEP162 centrosomal protein 162kDa
CFH complement factor H
CLCN3 chloride channel, voltage-sensitive 3
COL19A1 collagen, type XIX, alpha 1
COL8A1 collagen, type VIII, alpha 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPB2 carboxypeptidase B2 (plasma)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRHR1 corticotropin releasing hormone receptor 1
CTRL chymotrypsin-like
CXCL5 chemokine (C-X-C motif) ligand 5
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DBT dihydrolipoamide branched chain transacylase E2
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DKFZP434C153 DKFZP434C153 protein
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EN2 engrailed homeobox 2
EPHB2 EPH receptor B2
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERCC4 excision repair cross-complementation group 4
ESR1 estrogen receptor 1
EXOC4 exocyst complex component 4
FAM13A family with sequence similarity 13, member A
FAM153B family with sequence similarity 153, member B
FAS Fas cell surface death receptor
FBXL4 F-box and leucine-rich repeat protein 4
FGF18 fibroblast growth factor 18
FIG4 FIG4 phosphoinositide 5-phosphatase
FNTB farnesyltransferase, CAAX box, beta
FOSL1 FOS-like antigen 1
FRYL FRY-like
FSHR follicle stimulating hormone receptor
FZD5 frizzled class receptor 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCM1 glial cells missing homolog 1 (Drosophila)
GHRHR growth hormone releasing hormone receptor
GJB5 gap junction protein, beta 5, 31.1kDa
GLE1 GLE1 RNA export mediator
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH8 G patch domain containing 8
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR15 G protein-coupled receptor 15
GPR171 G protein-coupled receptor 171
GPR18 G protein-coupled receptor 18
GPR19 G protein-coupled receptor 19
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GUCY2C guanylate cyclase 2C
GUCY2F guanylate cyclase 2F, retinal
HCG8 HLA complex group 8
HCRTR2 hypocretin (orexin) receptor 2
HIST1H3E histone cluster 1, H3e
HNF1A HNF1 homeobox A
HOXD4 homeobox D4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IGKV7-3 immunoglobulin kappa variable 7-3 (pseudogene)
IL11RA interleukin 11 receptor, alpha
IL13 interleukin 13
IL16 interleukin 16
IL5 interleukin 5
IPO9 importin 9
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
JADE3 jade family PHD finger 3
JRK Jrk homolog (mouse)
JRKL JRK-like
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KDR kinase insert domain receptor
KLHL18 kelch-like family member 18
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KNG1 kininogen 1
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT2 keratin 2, type II
KRT33A keratin 33A, type I
KRT34 keratin 34, type I
KRT86 keratin 86, type II
LOR loricrin
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC48 leucine rich repeat containing 48
LTBP4 latent transforming growth factor beta binding protein 4
LY9 lymphocyte antigen 9
MAGEA8 melanoma antigen family A8
MAGEA9 melanoma antigen family A9
MC5R melanocortin 5 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFN1 mitofusin 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MON2 MON2 homolog (S. cerevisiae)
MSH3 mutS homolog 3
MSL3 male-specific lethal 3 homolog (Drosophila)
MUC8 mucin 8
NF1 neurofibromin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NHEJ1 nonhomologous end-joining factor 1
NMT2 N-myristoyltransferase 2
NOS2 nitric oxide synthase 2, inducible
NPFF neuropeptide FF-amide peptide precursor
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRP2 neuropilin 2
NRTN neurturin
NTNG2 netrin G2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OPRL1 opiate receptor-like 1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PAX6 paired box 6
PAX9 paired box 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCM1 pericentriolar material 1
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PGM3 phosphoglucomutase 3
PHF10 PHD finger protein 10
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHOX2B paired-like homeobox 2b
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POFUT2 protein O-fucosyltransferase 2
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POU6F1 POU class 6 homeobox 1
POU6F2 POU class 6 homeobox 2
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKCA protein kinase C, alpha
PSG1 pregnancy specific beta-1-glycoprotein 1
PTEN phosphatase and tensin homolog
PTPRB protein tyrosine phosphatase, receptor type, B
PVR poliovirus receptor
R3HCC1L R3H domain and coiled-coil containing 1-like
RAD51D RAD51 paralog D
RAP2C RAP2C, member of RAS oncogene family
RB1CC1 RB1-inducible coiled-coil 1
RBMXL1 RNA binding motif protein, X-linked-like 1
RORB RAR-related orphan receptor B
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RREB1 ras responsive element binding protein 1
RUNX2 runt-related transcription factor 2
RXRG retinoid X receptor, gamma
RYR3 ryanodine receptor 3
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SGPL1 sphingosine-1-phosphate lyase 1
SIM2 single-minded family bHLH transcription factor 2
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SPA17 sperm autoantigenic protein 17
SPAG11B sperm associated antigen 11B
SPATA2 spermatogenesis associated 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SULT4A1 sulfotransferase family 4A, member 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SURF2 surfeit 2
SYT5 synaptotagmin V
T T, brachyury homolog (mouse)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D22A TBC1 domain family, member 22A
TBX19 T-box 19
TBX5 T-box 5
TENM4 teneurin transmembrane protein 4
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TMEM11 transmembrane protein 11
TMEM26 transmembrane protein 26
TPD52 tumor protein D52
TRIM24 tripartite motif containing 24
TSPAN2 tetraspanin 2
TSSK2 testis-specific serine kinase 2
UBE4B ubiquitination factor E4B
WBP4 WW domain binding protein 4
ZBTB14 zinc finger and BTB domain containing 14
ZBTB22 zinc finger and BTB domain containing 22
ZBTB33 zinc finger and BTB domain containing 33
ZBTB40 zinc finger and BTB domain containing 40
ZNF133 zinc finger protein 133
ZNF134 zinc finger protein 134
ZNF141 zinc finger protein 141
ZNF157 zinc finger protein 157
ZNF200 zinc finger protein 200
ZNF202 zinc finger protein 202
ZNF266 zinc finger protein 266
ZNF33B zinc finger protein 33B
ZNF500 zinc finger protein 500
ZP2 zona pellucida glycoprotein 2 (sperm receptor)