IL2RB Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description interleukin 2 receptor, beta|The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3560)
External Link https://ncbi.nlm.nih.gov/gene/3560
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Genes

499 genes differentially expressed following the IL2RB gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 0.0224636
XIC X chromosome inactivation center 0.0172669
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0144357
LTF lactotransferrin 0.0142689
LEF1 lymphoid enhancer-binding factor 1 0.0131303
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.0128813
MMP9 matrix metallopeptidase 9 0.0125096
SMC1A structural maintenance of chromosomes 1A 0.0124032
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0123536
GREM1 gremlin 1, DAN family BMP antagonist 0.0113057
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0111145
COCH cochlin 0.0110393
G0S2 G0/G1 switch 2 0.0108488
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.0106726
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0105573
JCHAIN joining chain of multimeric IgA and IgM 0.0100942
NUSAP1 nucleolar and spindle associated protein 1 0.00989703
CDCA4 cell division cycle associated 4 0.00987689
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00984337
TXNIP thioredoxin interacting protein 0.00981076
DCLK1 doublecortin-like kinase 1 0.00977824
TOB1 transducer of ERBB2, 1 0.00974393
ZNF160 zinc finger protein 160 0.00946855
COMP cartilage oligomeric matrix protein 0.00943057
TSPYL5 TSPY-like 5 0.00936395
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00930013
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00910151
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00910082
AEBP1 AE binding protein 1 0.00899348
GOLM1 golgi membrane protein 1 0.00896825
LOXL1 lysyl oxidase-like 1 0.00895278
WDR7 WD repeat domain 7 0.00884932
TNC tenascin C 0.00877637
CCL19 chemokine (C-C motif) ligand 19 0.00876468
CTSK cathepsin K 0.00863229
MAP7 microtubule-associated protein 7 0.00847668
HAUS2 HAUS augmin-like complex, subunit 2 0.00844426
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00834048
DLK1 delta-like 1 homolog (Drosophila) 0.00833006
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.00828351
FTH1 ferritin, heavy polypeptide 1 0.00814075
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.00812802
FBXW12 F-box and WD repeat domain containing 12 0.00810843
COL6A3 collagen, type VI, alpha 3 0.00805794
BGN biglycan 0.00804772
PAX5 paired box 5 0.00801212
PRR11 proline rich 11 0.00794842
POMZP3 POM121 and ZP3 fusion 0.00792481
SIDT2 SID1 transmembrane family, member 2 0.00791226
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.00785227
NID2 nidogen 2 (osteonidogen) 0.00782551
GOLGA8A golgin A8 family, member A 0.00774816
FST follistatin 0.00770973
NPY neuropeptide Y 0.0077007
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00765905
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00765594
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00761494
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.00756733
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.00756712
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0075604
PCP4 Purkinje cell protein 4 0.00751451
SCG5 secretogranin V 0.00747606
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.00739739
CAMP cathelicidin antimicrobial peptide 0.0072428
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.00722522
LRRC15 leucine rich repeat containing 15 0.00720536
ZNF721 zinc finger protein 721 0.00713785
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.00712044
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00711202
COL10A1 collagen, type X, alpha 1 0.00710662
DMTF1 cyclin D binding myb-like transcription factor 1 0.00708796
LARS1 leucyl-tRNA synthetase 1 0.00706886
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.00704247
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.00703905
TARDBP TAR DNA binding protein 0.00697483
PRDX2 peroxiredoxin 2 0.00696648
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00696368
CLC Charcot-Leyden crystal galectin 0.00689269
PRPF4 pre-mRNA processing factor 4 0.00689246
HMGB2 high mobility group box 2 0.0068753
LRRN3 leucine rich repeat neuronal 3 0.00682638
TAGLN transgelin 0.00681192
SCGB2A2 secretoglobin, family 2A, member 2 0.00677275
MXRA8 matrix-remodelling associated 8 0.00675824
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00672662
TMSB15A thymosin beta 15a 0.00667141
HAUS3 HAUS augmin-like complex, subunit 3 0.00665752
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 0.00664357
FSTL1 follistatin-like 1 0.00659806
NTS neurotensin 0.00659377
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00657942
CD320 CD320 molecule 0.00657813
OLFM4 olfactomedin 4 0.0065533
CNN3 calponin 3, acidic 0.00653738
RBM26 RNA binding motif protein 26 0.00652755
STAB1 stabilin 1 0.00650092
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 0.00649414
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00645757
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00645632
MTARC1 mitochondrial amidoxime reducing component 1 0.00643962
GPX4 glutathione peroxidase 4 0.00642006
ISL1 ISL LIM homeobox 1 0.00640537
CD19 CD19 molecule 0.00639438
LYZ lysozyme 0.00639177
KLHL21 kelch-like family member 21 0.00636246
CTSG cathepsin G 0.00629816
CD79A CD79a molecule, immunoglobulin-associated alpha 0.00627743
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00623122
FBN2 fibrillin 2 0.0062147
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00620599
AGTR1 angiotensin II receptor, type 1 0.00619558
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.0061909
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00618324
GNAS GNAS complex locus 0.00616072
IRS2 insulin receptor substrate 2 0.00615843
SCAF4 SR-related CTD-associated factor 4 0.00613722
AGO3 argonaute RISC catalytic component 3 0.00612712
DMXL2 Dmx-like 2 0.00611359
OSBPL8 oxysterol binding protein-like 8 0.00610514
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00610016
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00608291
HMGB1 high mobility group box 1 0.00606887
IPO13 importin 13 0.00600561
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00598695
PDIA3 protein disulfide isomerase family A, member 3 0.00598377
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00595498
NUTF2 nuclear transport factor 2 0.00593739
PCDH9 protocadherin 9 0.00592041
DEFA4 defensin, alpha 4, corticostatin 0.00591725
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00591479
NVL nuclear VCP-like 0.00589786
TGFB1 transforming growth factor, beta 1 0.00587019
CDC20 cell division cycle 20 0.00586619
RUFY3 RUN and FYVE domain containing 3 0.00584548
ZNF329 zinc finger protein 329 0.00584433
PKP1 plakophilin 1 0.00582817
PCYOX1L prenylcysteine oxidase 1 like 0.00582562
FGR FGR proto-oncogene, Src family tyrosine kinase 0.00581736
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00580655
CCNI cyclin I 0.00579858
JMJD6 jumonji domain containing 6 0.00579198
EFNB2 ephrin-B2 0.0057719
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00577141
SPN sialophorin 0.00575438
COL16A1 collagen, type XVI, alpha 1 0.00574858
USP48 ubiquitin specific peptidase 48 0.00574553
TACC3 transforming, acidic coiled-coil containing protein 3 0.00573728
PDE10A phosphodiesterase 10A 0.00572945
CYBB cytochrome b-245, beta polypeptide 0.00572679
TPSAB1 tryptase alpha/beta 1 0.00571679
PDGFRL platelet-derived growth factor receptor-like 0.00571324
STXBP2 syntaxin binding protein 2 0.00570163
LY75 lymphocyte antigen 75 0.00569468
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 0.00568368
CD81 CD81 molecule 0.00567388
MFAP2 microfibrillar-associated protein 2 0.00561718
TTC37 tetratricopeptide repeat domain 37 0.00561149
NKX3-1 NK3 homeobox 1 0.00560799
TAOK1 TAO kinase 1 0.00559366
CLU clusterin 0.00558359
GUSBP3 glucuronidase, beta pseudogene 3 0.00555425
SAR1A secretion associated, Ras related GTPase 1A 0.00554492
HOXC6 homeobox C6 0.00554103
UBA1 ubiquitin-like modifier activating enzyme 1 0.00552212
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 0.00549836
POLR1B polymerase (RNA) I polypeptide B, 128kDa 0.00549271
NEIL1 nei endonuclease VIII-like 1 (E. coli) 0.00549072
HSPG2 heparan sulfate proteoglycan 2 0.00548631
PRSS3 protease, serine, 3 0.00548016
NOTCH2NL notch 2 N-terminal like 0.0054738
BASP1 brain abundant, membrane attached signal protein 1 0.00547243
GPRASP1 G protein-coupled receptor associated sorting protein 1 0.00546699
RAD21 RAD21 homolog (S. pombe) 0.00546359
TCL1A T-cell leukemia/lymphoma 1A 0.00545496
BCOR BCL6 corepressor 0.00544541
EIF5A eukaryotic translation initiation factor 5A 0.00543178
MCOLN1 mucolipin 1 0.00540216
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 0.00539947
GAL galanin/GMAP prepropeptide 0.00539714
PDGFC platelet derived growth factor C 0.00539323
ZNF611 zinc finger protein 611 0.00539163
POU2AF1 POU class 2 associating factor 1 0.00537056
CST7 cystatin F (leukocystatin) 0.0053667
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00534699
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00534545
MAOA monoamine oxidase A 0.00534083
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 0.00534076
ZFP36L1 ZFP36 ring finger protein-like 1 0.00532336
RTN3 reticulon 3 0.00530485
CKS2 CDC28 protein kinase regulatory subunit 2 0.00529786
HMG20B high mobility group 20B 0.0052918
CSAD cysteine sulfinic acid decarboxylase 0.00529176
THBS4 thrombospondin 4 0.00528572
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.00526021
EPHX2 epoxide hydrolase 2, cytoplasmic 0.00525418
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.00524473
SETD6 SET domain containing 6 0.00524095
CHKB choline kinase beta 0.0052236
LBR lamin B receptor 0.00521881
PIP prolactin-induced protein 0.0052167
RRM1 ribonucleotide reductase M1 0.00521138
COLEC12 collectin sub-family member 12 0.00520562
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 0.00519664
ZBTB20 zinc finger and BTB domain containing 20 0.0051792
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0051635
CBX5 chromobox homolog 5 0.00515043
ZFHX4 zinc finger homeobox 4 0.00514431
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.00514309
PSD3 pleckstrin and Sec7 domain containing 3 0.00513861
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00512768
AZU1 azurocidin 1 0.00512563
DBF4 DBF4 zinc finger 0.00512113
WNT5B wingless-type MMTV integration site family, member 5B 0.00511178
IL2RG interleukin 2 receptor, gamma 0.00509763
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 0.00509644
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 0.00508326
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00508077
CCNF cyclin F 0.00507695
C5AR1 complement component 5a receptor 1 0.00507329
TPD52 tumor protein D52 0.00507133
ENAH enabled homolog (Drosophila) 0.00507078
MT1X metallothionein 1X 0.00506953
GOLPH3L golgi phosphoprotein 3-like 0.00506072
CYTH1 cytohesin 1 0.00505182
BMP2K BMP2 inducible kinase 0.00505144
SDCBP syndecan binding protein (syntenin) 0.00504777
GALC galactosylceramidase 0.00504629
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00503865
DGKD diacylglycerol kinase, delta 130kDa 0.0050311
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.00503059
RACGAP1 Rac GTPase activating protein 1 0.00502393
CYTL1 cytokine-like 1 0.00500158
F5 coagulation factor V (proaccelerin, labile factor) 0.0049904
COPG1 coatomer protein complex, subunit gamma 1 0.00498399
MARCKSL1 MARCKS-like 1 0.00497551
CD83 CD83 molecule 0.00495479
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00495435
PIAS3 protein inhibitor of activated STAT, 3 0.0049433
TMEM131L transmembrane 131 like 0.00493955
SIRT3 sirtuin 3 0.00493736
SEC31A SEC31 homolog A (S. cerevisiae) 0.00493066
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00492836
TECR trans-2,3-enoyl-CoA reductase 0.00492602
TMX4 thioredoxin-related transmembrane protein 4 0.00491806
TNIK TRAF2 and NCK interacting kinase 0.00491663
TMEM63A transmembrane protein 63A 0.00490251
SUCO SUN domain containing ossification factor 0.00488941
SETMAR SET domain and mariner transposase fusion gene 0.0048798
AMPD3 adenosine monophosphate deaminase 3 0.00487744

decreased expression

Symbol Name Standardized Value
AKR1C3 aldo-keto reductase family 1, member C3 -0.0126378
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0124098
GAB2 GRB2-associated binding protein 2 -0.0122802
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.0119716
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0119297
SLPI secretory leukocyte peptidase inhibitor -0.0116854
TACSTD2 tumor-associated calcium signal transducer 2 -0.0116538
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.0115917
KDM5D lysine (K)-specific demethylase 5D -0.0115569
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0112255
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0111003
DEFB1 defensin, beta 1 -0.0109725
S100A8 S100 calcium binding protein A8 -0.0105286
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.00994421
EMX2 empty spiracles homeobox 2 -0.0097159
MYRF myelin regulatory factor -0.00963344
EMP2 epithelial membrane protein 2 -0.00955189
KLF6 Kruppel-like factor 6 -0.00936278
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00924249
COG7 component of oligomeric golgi complex 7 -0.00918232
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00909619
WFDC2 WAP four-disulfide core domain 2 -0.00894574
CCR2 chemokine (C-C motif) receptor 2 -0.00887828
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0088755
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00887359
LAMP3 lysosomal-associated membrane protein 3 -0.00886529
RTP4 receptor (chemosensory) transporter protein 4 -0.00884326
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00883145
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00863489
CFI complement factor I -0.00862948
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00861274
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.00858667
AKR1C2 aldo-keto reductase family 1, member C2 -0.00857693
SLC38A1 solute carrier family 38, member 1 -0.00853584
CLDN10 claudin 10 -0.00852883
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00852728
HSPB8 heat shock 22kDa protein 8 -0.00851945
AKR1C1 aldo-keto reductase family 1, member C1 -0.00847103
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00841722
TCTA T-cell leukemia translocation altered -0.00841542
CLIC5 chloride intracellular channel 5 -0.00837498
MX2 MX dynamin-like GTPase 2 -0.00834978
SMYD2 SET and MYND domain containing 2 -0.00827535
MX1 MX dynamin-like GTPase 1 -0.00824162
CES1 carboxylesterase 1 -0.00822017
MSLN mesothelin -0.00811565
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00807669
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00807666
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00807525
TLR4 toll-like receptor 4 -0.00804287
ASRGL1 asparaginase like 1 -0.00803396
TMEM176B transmembrane protein 176B -0.00796482
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.00794976
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00790033
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00783371
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00782482
LEPROT leptin receptor overlapping transcript -0.00781481
BAX BCL2-associated X protein -0.00767903
ANXA9 annexin A9 -0.00762929
KRT18 keratin 18, type I -0.00762592
AGPS alkylglycerone phosphate synthase -0.00761809
KLK10 kallikrein-related peptidase 10 -0.00758812
PRNP prion protein -0.00746338
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00745916
TP53I3 tumor protein p53 inducible protein 3 -0.00745273
ADAM28 ADAM metallopeptidase domain 28 -0.00743198
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00739801
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.00737745
ADIRF adipogenesis regulatory factor -0.00737393
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00728696
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00727305
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00725699
HPCAL1 hippocalcin-like 1 -0.00720238
PLK1 polo-like kinase 1 -0.00718768
TMEM230 transmembrane protein 230 -0.0071688
IFI44L interferon-induced protein 44-like -0.00716554
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.00716298
MDFIC MyoD family inhibitor domain containing -0.00715992
CFB complement factor B -0.00714019
S100A9 S100 calcium binding protein A9 -0.00711202
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00711162
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00703417
KRT7 keratin 7, type II -0.00701422
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00699442
IFI44 interferon-induced protein 44 -0.00693965
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00691521
FZD6 frizzled class receptor 6 -0.0068613
PROM1 prominin 1 -0.00680265
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00678428
TNNT1 troponin T type 1 (skeletal, slow) -0.00677606
PDZK1 PDZ domain containing 1 -0.00675938
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.00670833
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00670746
PDHX pyruvate dehydrogenase complex, component X -0.00667491
GDE1 glycerophosphodiester phosphodiesterase 1 -0.00665901
EXOC5 exocyst complex component 5 -0.00661785
TNS3 tensin 3 -0.00660783
CD93 CD93 molecule -0.00658976
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00658262
ARMT1 acidic residue methyltransferase 1 -0.00658229
TGM2 transglutaminase 2 -0.00656651
ABLIM1 actin binding LIM protein 1 -0.00654055
MVP major vault protein -0.00648267
YIPF5 Yip1 domain family, member 5 -0.0064816
UPK1B uroplakin 1B -0.00646461
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -0.00646064
JPT2 Jupiter microtubule associated homolog 2 -0.00645259
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.00645133
GPC3 glypican 3 -0.00640926
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00638785
SASH1 SAM and SH3 domain containing 1 -0.00637705
ADAM10 ADAM metallopeptidase domain 10 -0.00634876
CARHSP1 calcium regulated heat stable protein 1, 24kDa -0.00634847
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -0.006336
RNASET2 ribonuclease T2 -0.00632612
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00631444
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00630724
VAMP8 vesicle-associated membrane protein 8 -0.0062434
MUC16 mucin 16, cell surface associated -0.00624241
SPON1 spondin 1, extracellular matrix protein -0.00621623
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00621276
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00621094
SOX4 SRY (sex determining region Y)-box 4 -0.0062072
FERMT1 fermitin family member 1 -0.00619684
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00618004
CD200 CD200 molecule -0.00614535
TRAF3IP2 TRAF3 interacting protein 2 -0.00614374
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00612998
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.00607603
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -0.00606716
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00601463
LYPD1 LY6/PLAUR domain containing 1 -0.00599978
TDRD7 tudor domain containing 7 -0.00597433
DAAM1 dishevelled associated activator of morphogenesis 1 -0.00595153
ACKR3 atypical chemokine receptor 3 -0.00593058
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.00592353
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00590926
HBB hemoglobin, beta -0.00590526
PODXL podocalyxin-like -0.00589752
CARD10 caspase recruitment domain family, member 10 -0.0058944
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.00587572
C3 complement component 3 -0.00586019
TIGAR TP53 induced glycolysis regulatory phosphatase -0.00585092
ASXL2 additional sex combs like transcriptional regulator 2 -0.00584276
PECR peroxisomal trans-2-enoyl-CoA reductase -0.00584074
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00583484
ZNF706 zinc finger protein 706 -0.00581999
TFRC transferrin receptor -0.00580873
TSPAN1 tetraspanin 1 -0.00580104
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.00579725
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.00578838
KLK5 kallikrein-related peptidase 5 -0.00577202
RPP14 ribonuclease P/MRP 14kDa subunit -0.0057709
CALCOCO2 calcium binding and coiled-coil domain 2 -0.00576082
TANK TRAF family member-associated NFKB activator -0.00575713
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00574128
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00573204
AMDHD2 amidohydrolase domain containing 2 -0.00573092
MYOF myoferlin -0.00572987
NKG7 natural killer cell granule protein 7 -0.00571802
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00571802
ISG20 interferon stimulated exonuclease gene 20kDa -0.00571639
ODAM odontogenic, ameloblast asssociated -0.00567627
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00567219
CEMIP cell migration inducing protein, hyaluronan binding -0.00564798
STX3 syntaxin 3 -0.00563897
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00563359
GPX2 glutathione peroxidase 2 -0.00561877
ATG5 autophagy related 5 -0.0056011
ATF3 activating transcription factor 3 -0.00560077
MRPS28 mitochondrial ribosomal protein S28 -0.00560038
RBPMS RNA binding protein with multiple splicing -0.00558622
SINHCAF SIN3-HDAC complex associated factor -0.00558317
TMOD3 tropomodulin 3 (ubiquitous) -0.0055444
IL10RB interleukin 10 receptor, beta -0.00554149
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -0.00553336
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00552435
BAMBI BMP and activin membrane-bound inhibitor -0.00552284
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.00551687
FRMD4B FERM domain containing 4B -0.00551541
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00551522
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -0.005506
B9D1 B9 protein domain 1 -0.00549816
RANBP9 RAN binding protein 9 -0.00549562
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00548896
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00547675
PLS1 plastin 1 -0.00547294
HIP1 huntingtin interacting protein 1 -0.00546885
MET MET proto-oncogene, receptor tyrosine kinase -0.00546117
ZYX zyxin -0.00546018
ANXA2 annexin A2 -0.00545051
KLK8 kallikrein-related peptidase 8 -0.00543042
MYO5C myosin VC -0.00542599
MARCHF7 membrane associated ring-CH-type finger 7 -0.00542436
INAVA innate immunity activator -0.00542251
CTSH cathepsin H -0.00541371
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00541217
PLLP plasmolipin -0.00541006
PRKCQ protein kinase C, theta -0.00539334
TICAM1 toll-like receptor adaptor molecule 1 -0.00536819
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00532249
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00532055
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.00531183
TMEM135 transmembrane protein 135 -0.00529977
VRK3 vaccinia related kinase 3 -0.00528093
USP9Y ubiquitin specific peptidase 9, Y-linked -0.0052787
FLI1 Fli-1 proto-oncogene, ETS transcription factor -0.00527623
ELP5 elongator acetyltransferase complex subunit 5 -0.00527082
BCL6 B-cell CLL/lymphoma 6 -0.00526926
KLK7 kallikrein-related peptidase 7 -0.00526631
HIPK3 homeodomain interacting protein kinase 3 -0.00525203
NPR1 natriuretic peptide receptor 1 -0.00525021
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00523682
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00523495
ITM2C integral membrane protein 2C -0.00523484
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00521407
TMCO3 transmembrane and coiled-coil domains 3 -0.00521149
MID1 midline 1 -0.00520643
HSPB1 heat shock 27kDa protein 1 -0.00519824
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -0.0051922
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00519081
TRIM22 tripartite motif containing 22 -0.00518964
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -0.00518959
SCGB2A1 secretoglobin, family 2A, member 1 -0.00518656
CCL14 chemokine (C-C motif) ligand 14 -0.00518024
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 -0.00516008
SHTN1 shootin 1 -0.00514622
PLSCR1 phospholipid scramblase 1 -0.00514476
DMAC2L distal membrane arm assembly component 2 like -0.00514273
PGF placental growth factor -0.00514161
RAD23A RAD23 homolog A (S. cerevisiae) -0.0051415
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00513422
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.00513208
EDN3 endothelin 3 -0.00513124
IFI16 interferon, gamma-inducible protein 16 -0.00513024
KLK6 kallikrein-related peptidase 6 -0.00512002
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) -0.00511932
GSTP1 glutathione S-transferase pi 1 -0.0050826
OSMR oncostatin M receptor -0.00508236
ABHD4 abhydrolase domain containing 4 -0.00507852
CPM carboxypeptidase M -0.00507494
PDLIM1 PDZ and LIM domain 1 -0.005072
BFAR bifunctional apoptosis regulator -0.00506721
EPAS1 endothelial PAS domain protein 1 -0.00506508
LY96 lymphocyte antigen 96 -0.00506176
TMEM176A transmembrane protein 176A -0.00505769
PPP4C protein phosphatase 4, catalytic subunit -0.00504747
ETHE1 ethylmalonic encephalopathy 1 -0.00504401
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00503975
UVRAG UV radiation resistance associated -0.00503832