IL2RB Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description interleukin 2 receptor, beta|The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3560)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_IL2RB
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Genes

47 co-expressed genes for IL2RB from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABHD17A abhydrolase domain containing 17A
ADGRG1 adhesion G protein-coupled receptor G1
ARL4C ADP-ribosylation factor-like 4C
ASCL2 achaete-scute family bHLH transcription factor 2
CCL4 chemokine (C-C motif) ligand 4
CD160 CD160 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD247 CD247 molecule
CD7 CD7 molecule
CST7 cystatin F (leukocystatin)
CTSW cathepsin W
CX3CR1 chemokine (C-X3-C motif) receptor 1
GNLY granulysin
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
GZMM granzyme M (lymphocyte met-ase 1)
IL18RAP interleukin 18 receptor accessory protein
IL2RB interleukin 2 receptor, beta
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLRC3 killer cell lectin-like receptor subfamily C, member 3
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRF1 killer cell lectin-like receptor subfamily F, member 1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
MATK megakaryocyte-associated tyrosine kinase
MYOM2 myomesin 2
NCR3 natural cytotoxicity triggering receptor 3
NKG7 natural killer cell granule protein 7
PRF1 perforin 1 (pore forming protein)
PRKCH protein kinase C, eta
PTGDR prostaglandin D2 receptor (DP)
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RAB29 RAB29, member RAS oncogene family
RUNX3 runt-related transcription factor 3
S1PR5 sphingosine-1-phosphate receptor 5
SPON2 spondin 2, extracellular matrix protein
SUN2 Sad1 and UNC84 domain containing 2
TBX21 T-box 21
TRD T cell receptor delta locus
TTC38 tetratricopeptide repeat domain 38
XCL2 chemokine (C motif) ligand 2