| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | interleukin 4 receptor|This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012] (NCBI Entrez Gene Database, 3566) |
| External Link | https://ncbi.nlm.nih.gov/gene/3566 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the IL4R gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HOXC6 | homeobox C6 | 0.0130031 |
| CDCA4 | cell division cycle associated 4 | 0.0113345 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0111371 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.0103539 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00912784 |
| KIF20A | kinesin family member 20A | 0.00911348 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00898721 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00898385 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00864343 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00852626 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00838591 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00822909 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00814585 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00802322 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00788587 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00783663 |
| NVL | nuclear VCP-like | 0.00779874 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 0.00765879 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00765559 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00756309 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00718865 |
| FASN | fatty acid synthase | 0.0070935 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00709065 |
| HOXB6 | homeobox B6 | 0.00702355 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.0069718 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00696938 |
| PCP4 | Purkinje cell protein 4 | 0.00696652 |
| CALML5 | calmodulin-like 5 | 0.00692448 |
| CCNA2 | cyclin A2 | 0.00690383 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.006794 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00668046 |
| RWDD1 | RWD domain containing 1 | 0.00647381 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00646599 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.00646222 |
| TMX1 | thioredoxin-related transmembrane protein 1 | 0.00643593 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00641473 |
| RPS5 | ribosomal protein S5 | 0.00639534 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00635149 |
| HOXB2 | homeobox B2 | 0.00634267 |
| CD200 | CD200 molecule | 0.00632021 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00619907 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | 0.00613842 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00613494 |
| PCDH9 | protocadherin 9 | 0.00612406 |
| ANXA5 | annexin A5 | 0.00612247 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | 0.00605321 |
| CENPF | centromere protein F, 350/400kDa | 0.00603207 |
| CALD1 | caldesmon 1 | 0.00601932 |
| NSL1 | NSL1, MIS12 kinetochore complex component | 0.00601338 |
| FBXO5 | F-box protein 5 | 0.0060054 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00599312 |
| KIF14 | kinesin family member 14 | 0.00597093 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00594902 |
| HAL | histidine ammonia-lyase | 0.00590499 |
| FSTL1 | follistatin-like 1 | 0.00584775 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00584456 |
| CHN2 | chimerin 2 | 0.00582382 |
| CLC | Charcot-Leyden crystal galectin | 0.00580513 |
| NNMT | nicotinamide N-methyltransferase | 0.00579157 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00577972 |
| STMN1 | stathmin 1 | 0.00577313 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.0057717 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.0057584 |
| PFDN4 | prefoldin subunit 4 | 0.00573499 |
| COMMD8 | COMM domain containing 8 | 0.00570124 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00569831 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | 0.00569583 |
| COMP | cartilage oligomeric matrix protein | 0.00567074 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00566126 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00563535 |
| CYBRD1 | cytochrome b reductase 1 | 0.0055484 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.0055462 |
| PTTG1 | pituitary tumor-transforming 1 | 0.00554039 |
| LBR | lamin B receptor | 0.00553392 |
| NUP85 | nucleoporin 85kDa | 0.00553005 |
| FBXO28 | F-box protein 28 | 0.00550723 |
| MSRA | methionine sulfoxide reductase A | 0.00549579 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase | 0.00549352 |
| ENO1 | enolase 1, (alpha) | 0.00549153 |
| ESD | esterase D | 0.00549104 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00547921 |
| SDC2 | syndecan 2 | 0.0054579 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.00545215 |
| INSIG1 | insulin induced gene 1 | 0.00544276 |
| PON2 | paraoxonase 2 | 0.00543305 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00540498 |
| CCNB2 | cyclin B2 | 0.00539368 |
| NMU | neuromedin U | 0.00538981 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00538489 |
| GATA2 | GATA binding protein 2 | 0.005384 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.0053801 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | 0.00537492 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | 0.00537251 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | 0.00535902 |
| ACTR10 | actin-related protein 10 homolog (S. cerevisiae) | 0.00533542 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00532924 |
| TMPO | thymopoietin | 0.00532726 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00531307 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00530832 |
| FABP1 | fatty acid binding protein 1, liver | 0.00530618 |
| ATF5 | activating transcription factor 5 | 0.00530505 |
| RAB4A | RAB4A, member RAS oncogene family | 0.00529497 |
| FASTKD3 | FAST kinase domains 3 | 0.00524576 |
| GCH1 | GTP cyclohydrolase 1 | 0.0052429 |
| RAPSN | receptor-associated protein of the synapse | 0.00523991 |
| HOXB7 | homeobox B7 | 0.00522182 |
| DMBT1 | deleted in malignant brain tumors 1 | 0.00522016 |
| HMGB3 | high mobility group box 3 | 0.00516754 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0051571 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00514928 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00514925 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00514134 |
| AURKB | aurora kinase B | 0.00513799 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00513417 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00512489 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.00511232 |
| OIP5 | Opa interacting protein 5 | 0.00508802 |
| GLB1L2 | galactosidase, beta 1-like 2 | 0.00507157 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0050543 |
| TMEM14B | transmembrane protein 14B | 0.00501539 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00499524 |
| FGL2 | fibrinogen-like 2 | 0.00498355 |
| SRP9 | signal recognition particle 9kDa | 0.00498036 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00495574 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00495098 |
| AURKA | aurora kinase A | 0.00494433 |
| ARG1 | arginase 1 | 0.00493985 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.00493915 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00493824 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00492503 |
| CBX3 | chromobox homolog 3 | 0.00492242 |
| KRCC1 | lysine-rich coiled-coil 1 | 0.00491785 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00491476 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.004913 |
| RPA3 | replication protein A3, 14kDa | 0.00491279 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 0.00488158 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00486779 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00483045 |
| PBK | PDZ binding kinase | 0.00478028 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00476609 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00476569 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.00474705 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00474455 |
| HMGB1 | high mobility group box 1 | 0.00474225 |
| PLG | plasminogen | 0.00474167 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | 0.00473715 |
| MAP7 | microtubule-associated protein 7 | 0.00470875 |
| MKI67 | marker of proliferation Ki-67 | 0.00469667 |
| RPS17 | ribosomal protein S17 | 0.00468871 |
| EAF2 | ELL associated factor 2 | 0.00468328 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.00467173 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.0046537 |
| PRR11 | proline rich 11 | 0.00463847 |
| CD8A | CD8a molecule | 0.00463281 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00463 |
| SLC2A4RG | SLC2A4 regulator | 0.0046287 |
| C12ORF29 | chromosome 12 open reading frame 29 | 0.00460908 |
| MEX3D | mex-3 RNA binding family member D | 0.00460374 |
| HOXB5 | homeobox B5 | 0.00458973 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00458291 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00456193 |
| CENPE | centromere protein E, 312kDa | 0.0045595 |
| CPOX | coproporphyrinogen oxidase | 0.00455754 |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 0.00455498 |
| KIF11 | kinesin family member 11 | 0.00454964 |
| CDC25C | cell division cycle 25C | 0.00454218 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 0.00453614 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.0045303 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 0.00451467 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00450284 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00450146 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.00449681 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.004494 |
| SRP72 | signal recognition particle 72kDa | 0.00449124 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00449079 |
| LOR | loricrin | 0.00448617 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.00448488 |
| COMMD10 | COMM domain containing 10 | 0.00446708 |
| ADI1 | acireductone dioxygenase 1 | 0.00446611 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00446188 |
| ECT2 | epithelial cell transforming 2 | 0.00446157 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00445483 |
| KHK | ketohexokinase (fructokinase) | 0.00445052 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00444762 |
| CAMLG | calcium modulating ligand | 0.00444719 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.00444475 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.00444404 |
| ABHD10 | abhydrolase domain containing 10 | 0.0044303 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | 0.0044282 |
| DTYMK | deoxythymidylate kinase (thymidylate kinase) | 0.00442129 |
| HLTF | helicase-like transcription factor | 0.004409 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00438958 |
| COPS4 | COP9 signalosome subunit 4 | 0.00438493 |
| CLEC10A | C-type lectin domain family 10, member A | 0.00438129 |
| ELP5 | elongator acetyltransferase complex subunit 5 | 0.00437369 |
| DCK | deoxycytidine kinase | 0.0043627 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | 0.00435737 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00434521 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00433808 |
| AK4 | adenylate kinase 4 | 0.00433745 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.00433662 |
| OLFM1 | olfactomedin 1 | 0.00433596 |
| C7 | complement component 7 | 0.00433555 |
| CLIC2 | chloride intracellular channel 2 | 0.00433328 |
| PLN | phospholamban | 0.00432863 |
| TMEM47 | transmembrane protein 47 | 0.00432688 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.00432233 |
| DBF4 | DBF4 zinc finger | 0.00430452 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.00429896 |
| TEX30 | testis expressed 30 | 0.00429795 |
| NCK1 | NCK adaptor protein 1 | 0.00428061 |
| GUK1 | guanylate kinase 1 | 0.00428001 |
| CENPX | centromere protein X | 0.004279 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | 0.00426752 |
| SAC3D1 | SAC3 domain containing 1 | 0.00426442 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.0042601 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | 0.00425989 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00425785 |
| UCKL1 | uridine-cytidine kinase 1-like 1 | 0.00425214 |
| FOXM1 | forkhead box M1 | 0.00424965 |
| CTBP2 | C-terminal binding protein 2 | 0.00424425 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.00424359 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00424213 |
| DEPDC1 | DEP domain containing 1 | 0.00423794 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.00423056 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00422804 |
| ATF1 | activating transcription factor 1 | 0.004228 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 | 0.00421626 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0042135 |
| DUT | deoxyuridine triphosphatase | 0.00421274 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00421168 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00421014 |
| RTRAF | RNA transcription, translation and transport factor | 0.00420358 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00420247 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00420148 |
| HYOU1 | hypoxia up-regulated 1 | 0.00419553 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.00418813 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00418605 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 0.00418568 |
| FOLH1B | folate hydrolase 1B | 0.00418222 |
| MTCH2 | mitochondrial carrier 2 | 0.00417036 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00415299 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00414892 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00414886 |
| CDC20 | cell division cycle 20 | 0.0041437 |
| SUZ12 | SUZ12 polycomb repressive complex 2 subunit | 0.00414141 |
| PAH | phenylalanine hydroxylase | 0.00413725 |
| ILF2 | interleukin enhancer binding factor 2 | 0.00413395 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00412684 |
| F2R | coagulation factor II (thrombin) receptor | 0.00412284 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0156771 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0149741 |
| S100A8 | S100 calcium binding protein A8 | -0.0149374 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0125196 |
| S100A9 | S100 calcium binding protein A9 | -0.0119463 |
| KRT15 | keratin 15, type I | -0.0115512 |
| NRCAM | neuronal cell adhesion molecule | -0.0112019 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0108456 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.0103834 |
| ATF3 | activating transcription factor 3 | -0.0102326 |
| STC2 | stanniocalcin 2 | -0.00979731 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00979326 |
| KRT19 | keratin 19, type I | -0.00959891 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00949732 |
| LCN2 | lipocalin 2 | -0.00948348 |
| S100A11 | S100 calcium binding protein A11 | -0.00923447 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00920444 |
| MAGEA3 | melanoma antigen family A3 | -0.00919657 |
| KLK11 | kallikrein-related peptidase 11 | -0.00917561 |
| TCTA | T-cell leukemia translocation altered | -0.00916683 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0091118 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00885113 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00883043 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00880252 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00872665 |
| KRT18 | keratin 18, type I | -0.00867267 |
| CAST | calpastatin | -0.00865633 |
| EMP1 | epithelial membrane protein 1 | -0.00849323 |
| MAGEA12 | melanoma antigen family A12 | -0.0083711 |
| HMOX1 | heme oxygenase 1 | -0.00832543 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0082792 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00827722 |
| PLAUR | plasminogen activator, urokinase receptor | -0.00821556 |
| GLUL | glutamate-ammonia ligase | -0.0081665 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00797402 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00796066 |
| KRT13 | keratin 13, type I | -0.00793493 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.00783488 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0076802 |
| PLK2 | polo-like kinase 2 | -0.00767241 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00766676 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00765569 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00764268 |
| BMP2 | bone morphogenetic protein 2 | -0.00749581 |
| FOSL2 | FOS-like antigen 2 | -0.00748547 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00745532 |
| IL6 | interleukin 6 | -0.00745098 |
| SPRR3 | small proline-rich protein 3 | -0.00744023 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00743606 |
| IL1RN | interleukin 1 receptor antagonist | -0.00739693 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00737006 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0073381 |
| CLU | clusterin | -0.00727824 |
| FN1 | fibronectin 1 | -0.00722733 |
| S100A10 | S100 calcium binding protein A10 | -0.00720622 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00719688 |
| RGS4 | regulator of G-protein signaling 4 | -0.00717991 |
| PEG3 | paternally expressed 3 | -0.00706908 |
| OLFML2A | olfactomedin-like 2A | -0.00706505 |
| SIK1 | salt-inducible kinase 1 | -0.00704788 |
| RND3 | Rho family GTPase 3 | -0.00702519 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00692544 |
| KRT14 | keratin 14, type I | -0.00692117 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00687245 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0068699 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | -0.00683922 |
| MVP | major vault protein | -0.00682142 |
| BLVRB | biliverdin reductase B | -0.00675872 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00672445 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.00665474 |
| IER5 | immediate early response 5 | -0.00663186 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00660756 |
| CES1 | carboxylesterase 1 | -0.00657917 |
| GSR | glutathione reductase | -0.00656926 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00653099 |
| KLF2 | Kruppel-like factor 2 | -0.0064798 |
| MYOF | myoferlin | -0.00645165 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00640747 |
| MT1X | metallothionein 1X | -0.00640028 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00639874 |
| CRYAB | crystallin, alpha B | -0.0063927 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00638795 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00638371 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00638164 |
| ZFP36 | ZFP36 ring finger protein | -0.00636186 |
| TNNC1 | troponin C type 1 (slow) | -0.00633618 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00624851 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00623446 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00621623 |
| JUNB | jun B proto-oncogene | -0.00619446 |
| AK1 | adenylate kinase 1 | -0.00607728 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00605347 |
| CD37 | CD37 molecule | -0.00602616 |
| GRN | granulin | -0.00601902 |
| JUP | junction plakoglobin | -0.00601455 |
| CORO1A | coronin, actin binding protein, 1A | -0.00600748 |
| BTG2 | BTG family, member 2 | -0.00600493 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 | -0.00598331 |
| CD14 | CD14 molecule | -0.0059811 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00596096 |
| EFNA1 | ephrin-A1 | -0.0059572 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0059045 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00587394 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00586533 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00581292 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.00578658 |
| HOMER1 | homer scaffolding protein 1 | -0.00577789 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00577753 |
| C3 | complement component 3 | -0.00576193 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -0.00575234 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00574727 |
| CTSD | cathepsin D | -0.00574165 |
| LAMB3 | laminin, beta 3 | -0.00573714 |
| TTN | titin | -0.00573204 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00566772 |
| ZYX | zyxin | -0.00565929 |
| FCGBP | Fc fragment of IgG binding protein | -0.00564899 |
| TICAM1 | toll-like receptor adaptor molecule 1 | -0.00564485 |
| SMAD3 | SMAD family member 3 | -0.00564155 |
| ANXA1 | annexin A1 | -0.00561236 |
| ZC3H12A | zinc finger CCCH-type containing 12A | -0.00560631 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00557736 |
| CLDN7 | claudin 7 | -0.00557414 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00557278 |
| IL7R | interleukin 7 receptor | -0.00556269 |
| KRT23 | keratin 23, type I | -0.00556143 |
| GATA6 | GATA binding protein 6 | -0.00554482 |
| KYNU | kynureninase | -0.00554402 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00553756 |
| PLD3 | phospholipase D family, member 3 | -0.00546083 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.0054419 |
| GM2A | GM2 ganglioside activator | -0.00544073 |
| TLR4 | toll-like receptor 4 | -0.00543828 |
| APOD | apolipoprotein D | -0.00543593 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00543434 |
| HK2 | hexokinase 2 | -0.00542982 |
| INHBA | inhibin, beta A | -0.00541864 |
| RIN2 | Ras and Rab interactor 2 | -0.0054105 |
| MAGEA1 | melanoma antigen family A1 | -0.00540355 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.00540183 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00536669 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00535597 |
| PLXND1 | plexin D1 | -0.00534142 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00533795 |
| CTSB | cathepsin B | -0.00533566 |
| RTN2 | reticulon 2 | -0.00532215 |
| ETHE1 | ethylmalonic encephalopathy 1 | -0.00532156 |
| CFD | complement factor D (adipsin) | -0.00531708 |
| ABHD4 | abhydrolase domain containing 4 | -0.00531678 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00530443 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.00530351 |
| IL1B | interleukin 1, beta | -0.00528408 |
| IRS2 | insulin receptor substrate 2 | -0.00528172 |
| RNASET2 | ribonuclease T2 | -0.00527665 |
| COL5A2 | collagen, type V, alpha 2 | -0.00527509 |
| ZNF91 | zinc finger protein 91 | -0.00527335 |
| EGR1 | early growth response 1 | -0.0052693 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00525252 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00524858 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00524287 |
| CD9 | CD9 molecule | -0.00524067 |
| CTSL | cathepsin L | -0.00523899 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00523544 |
| CLCA4 | chloride channel accessory 4 | -0.00523041 |
| TRIM29 | tripartite motif containing 29 | -0.00522091 |
| H1-2 | H1.2 linker histone, cluster member | -0.00520515 |
| GSTZ1 | glutathione S-transferase zeta 1 | -0.00520342 |
| SVIL | supervillin | -0.0051994 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00519692 |
| VWF | von Willebrand factor | -0.00519393 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | -0.00519126 |
| MYBPC1 | myosin binding protein C, slow type | -0.00517587 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00516589 |
| SQSTM1 | sequestosome 1 | -0.00516154 |
| STXBP2 | syntaxin binding protein 2 | -0.00515257 |
| FHL2 | four and a half LIM domains 2 | -0.00513975 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00513963 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00512977 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.00512419 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00511061 |
| S100A12 | S100 calcium binding protein A12 | -0.00506961 |
| NOTCH1 | notch 1 | -0.0050688 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | -0.00506358 |
| SPP1 | secreted phosphoprotein 1 | -0.00506001 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00505827 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.00504811 |
| ACKR3 | atypical chemokine receptor 3 | -0.00501472 |
| MAGED2 | melanoma antigen family D2 | -0.00501462 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -0.00499776 |
| STC1 | stanniocalcin 1 | -0.00498381 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -0.00498191 |
| PERP | PERP, TP53 apoptosis effector | -0.00496143 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.0049512 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0049505 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00494879 |
| MCL1 | myeloid cell leukemia 1 | -0.00493862 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00492676 |
| HBEGF | heparin-binding EGF-like growth factor | -0.00491083 |
| GSTK1 | glutathione S-transferase kappa 1 | -0.0049072 |
| ALAS1 | 5'-aminolevulinate synthase 1 | -0.00490456 |
| TSPO | translocator protein (18kDa) | -0.00489606 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00487567 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00486581 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00485965 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00485829 |
| NMRK1 | nicotinamide riboside kinase 1 | -0.00485795 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00485546 |
| INAVA | innate immunity activator | -0.00484364 |
| EHD3 | EH-domain containing 3 | -0.00482384 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00482204 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00481641 |
| CA12 | carbonic anhydrase XII | -0.00481478 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00480797 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | -0.00478548 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00477241 |
| CKM | creatine kinase, muscle | -0.00476984 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.00476824 |
| GLA | galactosidase, alpha | -0.00475592 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00475429 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00475019 |
| RRAD | Ras-related associated with diabetes | -0.0047492 |
| CYB561 | cytochrome b561 | -0.00474918 |
| PTHLH | parathyroid hormone-like hormone | -0.00473768 |
| TLK2 | tousled-like kinase 2 | -0.00472492 |
| TUFT1 | tuftelin 1 | -0.00471595 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00471472 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.00471364 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00471201 |
| COBL | cordon-bleu WH2 repeat protein | -0.0046978 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00469173 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.0046838 |
| IRF6 | interferon regulatory factor 6 | -0.0046836 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -0.00468321 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00468253 |
| UPP1 | uridine phosphorylase 1 | -0.00467396 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00467308 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0046678 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00465945 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00465737 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.00463474 |
| ITK | IL2-inducible T-cell kinase | -0.00463265 |
| C5AR1 | complement component 5a receptor 1 | -0.00461636 |
| IL1A | interleukin 1, alpha | -0.0046065 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00460175 |
| CD163 | CD163 molecule | -0.00459799 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.00459445 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00459178 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | -0.00459128 |
| TSPAN7 | tetraspanin 7 | -0.00457102 |
