| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | interleukin 6 signal transducer|The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014] (NCBI Entrez Gene Database, 3572) |
| External Link | https://ncbi.nlm.nih.gov/gene/3572 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the IL6ST gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.018273 |
| MAL | mal, T-cell differentiation protein | 0.0173394 |
| SPRR3 | small proline-rich protein 3 | 0.0166671 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.01526 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0136627 |
| PTHLH | parathyroid hormone-like hormone | 0.0134578 |
| XIC | X chromosome inactivation center | 0.0130809 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0118789 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.0118126 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0116316 |
| HOXC6 | homeobox C6 | 0.011042 |
| CD9 | CD9 molecule | 0.0108476 |
| MAP7 | microtubule-associated protein 7 | 0.0106857 |
| DEFB4A | defensin, beta 4A | 0.0105075 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0104232 |
| ZNF652 | zinc finger protein 652 | 0.0102438 |
| SPRR2B | small proline-rich protein 2B | 0.0100156 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00998402 |
| KRT13 | keratin 13, type I | 0.0098679 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00980979 |
| CHI3L2 | chitinase 3-like 2 | 0.0096626 |
| WIF1 | WNT inhibitory factor 1 | 0.00957183 |
| CADM1 | cell adhesion molecule 1 | 0.00952934 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00949986 |
| NEBL | nebulette | 0.00946948 |
| CORO1C | coronin, actin binding protein, 1C | 0.00945545 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00914009 |
| CHGB | chromogranin B | 0.00911777 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.00889015 |
| COG7 | component of oligomeric golgi complex 7 | 0.00880056 |
| RHCG | Rh family, C glycoprotein | 0.0087374 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00860454 |
| GLTP | glycolipid transfer protein | 0.00857851 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0085685 |
| AIM2 | absent in melanoma 2 | 0.00856362 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00854881 |
| BMP7 | bone morphogenetic protein 7 | 0.0084779 |
| WSB2 | WD repeat and SOCS box containing 2 | 0.00841569 |
| UBB | ubiquitin B | 0.00829045 |
| CETN2 | centrin, EF-hand protein, 2 | 0.008262 |
| S100A10 | S100 calcium binding protein A10 | 0.00821376 |
| RNASET2 | ribonuclease T2 | 0.00818722 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | 0.00815614 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | 0.00814884 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00814824 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00812189 |
| PCDH9 | protocadherin 9 | 0.00811828 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00799619 |
| ABLIM1 | actin binding LIM protein 1 | 0.00787575 |
| TSPAN1 | tetraspanin 1 | 0.00787391 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00783699 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.0077598 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00774323 |
| STAC | SH3 and cysteine rich domain | 0.00773545 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00773435 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00772346 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00771664 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00766288 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00752647 |
| CTSS | cathepsin S | 0.00751801 |
| RPS17 | ribosomal protein S17 | 0.00751508 |
| PLEK2 | pleckstrin 2 | 0.00751445 |
| GSN | gelsolin | 0.00751151 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0075024 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00748929 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00742769 |
| ANGPT1 | angiopoietin 1 | 0.00735947 |
| EGR1 | early growth response 1 | 0.00734366 |
| KYNU | kynureninase | 0.00734306 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00733736 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00733402 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00730172 |
| NPR3 | natriuretic peptide receptor 3 | 0.00723517 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00722875 |
| TPD52L1 | tumor protein D52-like 1 | 0.00716144 |
| WASHC4 | WASH complex subunit 4 | 0.00715067 |
| FGF13 | fibroblast growth factor 13 | 0.00711502 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00708946 |
| S100A11 | S100 calcium binding protein A11 | 0.00707324 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.00706737 |
| TGFB2 | transforming growth factor, beta 2 | 0.00706657 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00702134 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) | 0.00700771 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00700596 |
| KLK6 | kallikrein-related peptidase 6 | 0.00700361 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.0069963 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.0069763 |
| IL6ST | interleukin 6 signal transducer | 0.00697412 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00696518 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00696169 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00686872 |
| TSPAN5 | tetraspanin 5 | 0.00686497 |
| L1CAM | L1 cell adhesion molecule | 0.00686338 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00686181 |
| LTA4H | leukotriene A4 hydrolase | 0.00686161 |
| AUTS2 | autism susceptibility candidate 2 | 0.00681349 |
| OCA2 | oculocutaneous albinism II | 0.00679281 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00678131 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00672338 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00668612 |
| PUDP | pseudouridine 5'-phosphatase | 0.00668361 |
| PALLD | palladin, cytoskeletal associated protein | 0.00665982 |
| SPRR1A | small proline-rich protein 1A | 0.00665824 |
| SYT1 | synaptotagmin I | 0.00665666 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.00665098 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0066476 |
| MX1 | MX dynamin-like GTPase 1 | 0.00661716 |
| SERINC5 | serine incorporator 5 | 0.00661443 |
| TMCC2 | transmembrane and coiled-coil domain family 2 | 0.00658615 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.00657141 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00656182 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00654417 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.00654397 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00654023 |
| SYNGR2 | synaptogyrin 2 | 0.00653173 |
| PRKCQ | protein kinase C, theta | 0.00651785 |
| TESC | tescalcin | 0.0065119 |
| CD1B | CD1b molecule | 0.0064853 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.00648102 |
| TAGLN2 | transgelin 2 | 0.006465 |
| EVI2A | ecotropic viral integration site 2A | 0.00644096 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00643978 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 0.00642417 |
| ZNF430 | zinc finger protein 430 | 0.0064222 |
| RBM34 | RNA binding motif protein 34 | 0.00638911 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | 0.00638536 |
| CHIT1 | chitinase 1 (chitotriosidase) | 0.00633943 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.00633665 |
| VSNL1 | visinin-like 1 | 0.0063358 |
| HLA-F-AS1 | HLA-F antisense RNA 1 | 0.00633345 |
| CNTN1 | contactin 1 | 0.00632201 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | 0.00631308 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.0063067 |
| ATF3 | activating transcription factor 3 | 0.00630572 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00629408 |
| PLS3 | plastin 3 | 0.00629058 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00628912 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.00627824 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00625135 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00624049 |
| STK17A | serine/threonine kinase 17a | 0.00623247 |
| IFT57 | intraflagellar transport 57 | 0.00621947 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.006203 |
| HOXC10 | homeobox C10 | 0.0061831 |
| CTTN | cortactin | 0.00615854 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.00610746 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.00609877 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.00609154 |
| CSTA | cystatin A (stefin A) | 0.00609152 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00608717 |
| SIRPG | signal-regulatory protein gamma | 0.00607868 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00607433 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00607392 |
| RPL26 | ribosomal protein L26 | 0.00606387 |
| GAP43 | growth associated protein 43 | 0.00606224 |
| ATXN1 | ataxin 1 | 0.00605504 |
| LARP6 | La ribonucleoprotein domain family, member 6 | 0.00605111 |
| SH3GL3 | SH3-domain GRB2-like 3 | 0.00604375 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00604145 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 | 0.00603251 |
| CD48 | CD48 molecule | 0.00602223 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00600814 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00600621 |
| PTK2 | protein tyrosine kinase 2 | 0.00600571 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00598956 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.0059826 |
| DLX2 | distal-less homeobox 2 | 0.00597978 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.00597437 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.00596905 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | 0.00595518 |
| ERP44 | endoplasmic reticulum protein 44 | 0.00594292 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00593839 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.00592096 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00591235 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0058984 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00589727 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.00588961 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00588614 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0058847 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | 0.00588225 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.00587871 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | 0.00587666 |
| LAMC2 | laminin, gamma 2 | 0.00587361 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | 0.00584103 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.00583997 |
| RRAGD | Ras-related GTP binding D | 0.00582821 |
| AVPI1 | arginine vasopressin-induced 1 | 0.00582774 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00582337 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00580811 |
| CD83 | CD83 molecule | 0.00580306 |
| CDC42 | cell division cycle 42 | 0.00578119 |
| SIK1 | salt-inducible kinase 1 | 0.00578009 |
| LCN2 | lipocalin 2 | 0.00577215 |
| NSUN3 | NOP2/Sun domain family, member 3 | 0.00576646 |
| CCNA1 | cyclin A1 | 0.00576226 |
| TRAPPC2 | trafficking protein particle complex 2 | 0.00575506 |
| B2M | beta-2-microglobulin | 0.00574828 |
| RGS10 | regulator of G-protein signaling 10 | 0.00572646 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | 0.005716 |
| THBD | thrombomodulin | 0.00571558 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00571192 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00571124 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00569786 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.0056853 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00568507 |
| CTSB | cathepsin B | 0.00567582 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00567489 |
| DEFB1 | defensin, beta 1 | 0.00566607 |
| ADM | adrenomedullin | 0.0056606 |
| TNC | tenascin C | 0.00565656 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00565143 |
| ACP1 | acid phosphatase 1, soluble | 0.00564599 |
| RGS1 | regulator of G-protein signaling 1 | 0.00564417 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00564135 |
| LPXN | leupaxin | 0.00563747 |
| TMPRSS11D | transmembrane protease, serine 11D | 0.00563166 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | 0.00562967 |
| CLDND1 | claudin domain containing 1 | 0.0056296 |
| TUFT1 | tuftelin 1 | 0.00561731 |
| PFDN4 | prefoldin subunit 4 | 0.0056131 |
| C9ORF3 | chromosome 9 open reading frame 3 | 0.00555711 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.0055484 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00554375 |
| SFTPA2 | surfactant protein A2 | 0.00554307 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.0055279 |
| TSPAN6 | tetraspanin 6 | 0.00552769 |
| CLCA4 | chloride channel accessory 4 | 0.00552626 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.00551875 |
| STMN4 | stathmin-like 4 | 0.00551765 |
| POPDC3 | popeye domain containing 3 | 0.00549885 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | 0.00549761 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.0054877 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00545251 |
| MED6 | mediator complex subunit 6 | 0.00544895 |
| TFRC | transferrin receptor | 0.00543895 |
| UBASH3A | ubiquitin associated and SH3 domain containing A | 0.00543851 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | 0.00542103 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 | 0.00541189 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00540243 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00539814 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00537874 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.00537452 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00536343 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00534476 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00534426 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00534289 |
| ZNF277 | zinc finger protein 277 | 0.00533727 |
| MRPL42 | mitochondrial ribosomal protein L42 | 0.005325 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00532242 |
| HLA-F | major histocompatibility complex, class I, F | 0.00532033 |
| Symbol | Name | Standardized Value |
|---|---|---|
| WDR7 | WD repeat domain 7 | -0.0229597 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0207499 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0179596 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0172557 |
| DSP | desmoplakin | -0.0141715 |
| LTF | lactotransferrin | -0.0139833 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0132159 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0131856 |
| CDC20 | cell division cycle 20 | -0.0122885 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.0120464 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0119982 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.011861 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.011387 |
| RAPSN | receptor-associated protein of the synapse | -0.0112273 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.0110006 |
| TGFB1 | transforming growth factor, beta 1 | -0.0108162 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.0106708 |
| STXBP2 | syntaxin binding protein 2 | -0.0104868 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0102738 |
| OLFM4 | olfactomedin 4 | -0.0100586 |
| TSPAN4 | tetraspanin 4 | -0.0100346 |
| CLC | Charcot-Leyden crystal galectin | -0.0100314 |
| PLK1 | polo-like kinase 1 | -0.0100076 |
| ACTN1 | actinin, alpha 1 | -0.00982579 |
| ASPN | asporin | -0.0098232 |
| AEBP1 | AE binding protein 1 | -0.00971966 |
| CP | ceruloplasmin (ferroxidase) | -0.00959458 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00952406 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00930743 |
| COL3A1 | collagen, type III, alpha 1 | -0.0091993 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00915764 |
| NID1 | nidogen 1 | -0.00900605 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00895629 |
| PRTN3 | proteinase 3 | -0.00890113 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00885794 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00874149 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00874084 |
| APOD | apolipoprotein D | -0.00873842 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00868586 |
| PDGFD | platelet derived growth factor D | -0.00866997 |
| DCN | decorin | -0.00864116 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0085565 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0085544 |
| CD320 | CD320 molecule | -0.00852117 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00850872 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00850017 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00849506 |
| CFB | complement factor B | -0.00847404 |
| S100A8 | S100 calcium binding protein A8 | -0.00845846 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.00841773 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0082857 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00827507 |
| CD93 | CD93 molecule | -0.00824731 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00822772 |
| PITX3 | paired-like homeodomain 3 | -0.00822453 |
| DAPK1 | death-associated protein kinase 1 | -0.00817215 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa | -0.00815977 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00811157 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00811142 |
| AZU1 | azurocidin 1 | -0.00808503 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00805053 |
| FUS | FUS RNA binding protein | -0.00794432 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00789613 |
| NCOA2 | nuclear receptor coactivator 2 | -0.00787715 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | -0.00784076 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | -0.00777209 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00775853 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00768918 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00768864 |
| TSC2 | tuberous sclerosis 2 | -0.00761337 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00757713 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00746857 |
| CFD | complement factor D (adipsin) | -0.00745329 |
| DGKZ | diacylglycerol kinase, zeta | -0.00744725 |
| FAM117A | family with sequence similarity 117, member A | -0.00743868 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.00743729 |
| BCHE | butyrylcholinesterase | -0.00735033 |
| MSX1 | msh homeobox 1 | -0.00733965 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00731153 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | -0.00729873 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -0.00725512 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00724818 |
| GUSB | glucuronidase, beta | -0.0072471 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00716437 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00712939 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | -0.00706662 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | -0.00705522 |
| KLK5 | kallikrein-related peptidase 5 | -0.0070469 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00700986 |
| GAS1 | growth arrest-specific 1 | -0.00700558 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00700195 |
| PLIN2 | perilipin 2 | -0.0069967 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00695748 |
| RCOR1 | REST corepressor 1 | -0.00692732 |
| FLOT1 | flotillin 1 | -0.0069219 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00687608 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00687516 |
| EPCAM | epithelial cell adhesion molecule | -0.00685942 |
| PTGDR | prostaglandin D2 receptor (DP) | -0.0068171 |
| MAT2A | methionine adenosyltransferase II, alpha | -0.00680234 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00679442 |
| CCN3 | cellular communication network factor 3 | -0.00677255 |
| COQ8A | coenzyme Q8A | -0.00674592 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00674551 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0067433 |
| OBSL1 | obscurin-like 1 | -0.00674099 |
| TMSB15A | thymosin beta 15a | -0.00670326 |
| TXNL1 | thioredoxin-like 1 | -0.00670239 |
| ASRGL1 | asparaginase like 1 | -0.00667264 |
| TBL3 | transducin (beta)-like 3 | -0.00666861 |
| HSPA13 | heat shock protein 70kDa family, member 13 | -0.00663898 |
| FBLN2 | fibulin 2 | -0.00663814 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00663402 |
| SCRIB | scribbled planar cell polarity protein | -0.00659369 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00657482 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00656904 |
| LRRC15 | leucine rich repeat containing 15 | -0.00656673 |
| STK25 | serine/threonine kinase 25 | -0.00654884 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00653356 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00653153 |
| CXXC1 | CXXC finger protein 1 | -0.00653016 |
| FASN | fatty acid synthase | -0.00652291 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00651808 |
| PLVAP | plasmalemma vesicle associated protein | -0.00650051 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | -0.00649664 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00646085 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase | -0.00646042 |
| FAM169A | family with sequence similarity 169, member A | -0.00645267 |
| H1-10 | H1.10 linker histone | -0.00643776 |
| C20ORF27 | chromosome 20 open reading frame 27 | -0.00642457 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.0064054 |
| NKG7 | natural killer cell granule protein 7 | -0.0063864 |
| GRK2 | G protein-coupled receptor kinase 2 | -0.00638371 |
| NUDC | nudC nuclear distribution protein | -0.00637773 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.00635703 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.00632586 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00632493 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00629082 |
| MFAP5 | microfibrillar associated protein 5 | -0.00628422 |
| FOXM1 | forkhead box M1 | -0.0062476 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -0.00624736 |
| SELENBP1 | selenium binding protein 1 | -0.00624404 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.0061938 |
| BOP1 | block of proliferation 1 | -0.00618562 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.00616209 |
| TXNL4A | thioredoxin-like 4A | -0.00614791 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit | -0.00614389 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | -0.00613954 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00613801 |
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 | -0.00611039 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00609473 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00608913 |
| TARDBP | TAR DNA binding protein | -0.0060793 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | -0.00607526 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00607356 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N | -0.00606335 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | -0.00604982 |
| CDC25B | cell division cycle 25B | -0.00603778 |
| MYO1F | myosin IF | -0.00602204 |
| APOM | apolipoprotein M | -0.00601636 |
| BRD4 | bromodomain containing 4 | -0.00600848 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | -0.00599974 |
| USP25 | ubiquitin specific peptidase 25 | -0.00599941 |
| THY1 | Thy-1 cell surface antigen | -0.00599127 |
| TRAPPC8 | trafficking protein particle complex 8 | -0.00597198 |
| ABHD3 | abhydrolase domain containing 3 | -0.00596915 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00596053 |
| THAP12 | THAP domain containing 12 | -0.00594413 |
| KRT15 | keratin 15, type I | -0.00593744 |
| TYMS | thymidylate synthetase | -0.00593559 |
| PNN | pinin, desmosome associated protein | -0.00593012 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00591538 |
| MMP1 | matrix metallopeptidase 1 | -0.0059137 |
| BAG6 | BCL2-associated athanogene 6 | -0.00590637 |
| APMAP | adipocyte plasma membrane associated protein | -0.00590474 |
| APOB | apolipoprotein B | -0.00590061 |
| RRAGA | Ras-related GTP binding A | -0.00589932 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00589907 |
| TGFB3 | transforming growth factor, beta 3 | -0.00588846 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) | -0.00586286 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.00586213 |
| FABP1 | fatty acid binding protein 1, liver | -0.00585125 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00584254 |
| CEL | carboxyl ester lipase | -0.0058355 |
| PLCH1 | phospholipase C, eta 1 | -0.00583454 |
| FHOD1 | formin homology 2 domain containing 1 | -0.00583015 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00582708 |
| CTBP1 | C-terminal binding protein 1 | -0.00579142 |
| PNLIPRP2 | pancreatic lipase-related protein 2 | -0.00578994 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00578669 |
| CENPT | centromere protein T | -0.00578657 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00577212 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00576708 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00575447 |
| TBCD | tubulin folding cofactor D | -0.00575445 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00575379 |
| CCN2 | cellular communication network factor 2 | -0.00574987 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00573008 |
| FGB | fibrinogen beta chain | -0.00572225 |
| THOC6 | THO complex 6 | -0.00570056 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.00569796 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.00567623 |
| MTTP | microsomal triglyceride transfer protein | -0.00564607 |
| MMP11 | matrix metallopeptidase 11 | -0.0056349 |
| H1-2 | H1.2 linker histone, cluster member | -0.00562052 |
| COMP | cartilage oligomeric matrix protein | -0.00557957 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -0.00556889 |
| RANGAP1 | Ran GTPase activating protein 1 | -0.00556044 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.00555875 |
| SULT2A1 | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | -0.00555134 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00554172 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) | -0.00554169 |
| CENPB | centromere protein B, 80kDa | -0.00554108 |
| LYST | lysosomal trafficking regulator | -0.00553178 |
| VEGFA | vascular endothelial growth factor A | -0.00553095 |
| MICALL2 | MICAL-like 2 | -0.00552668 |
| MAEA | macrophage erythroblast attacher | -0.00551139 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00550779 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.00549631 |
| KRT1 | keratin 1, type II | -0.00545926 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00544729 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | -0.00544151 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00544099 |
| GRP | gastrin-releasing peptide | -0.00543755 |
| WT1 | Wilms tumor 1 | -0.00542844 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | -0.00542719 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00542577 |
| CDO1 | cysteine dioxygenase type 1 | -0.00542526 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00542325 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00542056 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00541985 |
| LAMB2 | laminin, beta 2 (laminin S) | -0.00540951 |
| MCM5 | minichromosome maintenance complex component 5 | -0.0053991 |
| SMAD7 | SMAD family member 7 | -0.00539419 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -0.00539185 |
| DVL1 | dishevelled segment polarity protein 1 | -0.00539072 |
| AKR1C4 | aldo-keto reductase family 1, member C4 | -0.0053774 |
| KRT14 | keratin 14, type I | -0.00537531 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00537424 |
| JMJD6 | jumonji domain containing 6 | -0.00537005 |
| KRT8 | keratin 8, type II | -0.00536871 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00536559 |
| GAA | glucosidase, alpha; acid | -0.00536392 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | -0.00534857 |
| LUC7L | LUC7-like (S. cerevisiae) | -0.00534818 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00534054 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00532508 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00531905 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00531497 |
