| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | IMP (inosine 5'-monophosphate) dehydrogenase 2|This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3615) |
| External Link | https://ncbi.nlm.nih.gov/gene/3615 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the IMPDH2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT19 | keratin 19, type I | 0.0126649 |
| CST3 | cystatin C | 0.0105054 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00938087 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00917464 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.0088661 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00811559 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00751494 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00751391 |
| CPE | carboxypeptidase E | 0.00729551 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00719919 |
| METTL7A | methyltransferase like 7A | 0.00708498 |
| PON2 | paraoxonase 2 | 0.00705913 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00694716 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00692017 |
| CA2 | carbonic anhydrase II | 0.00686034 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00685347 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.00672101 |
| GPX3 | glutathione peroxidase 3 | 0.00670877 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00667979 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0065208 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.0065086 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00647493 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00645495 |
| CADM1 | cell adhesion molecule 1 | 0.00642924 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00642795 |
| C1S | complement component 1, s subcomponent | 0.00642016 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00632731 |
| CTSZ | cathepsin Z | 0.00617602 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00608871 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00608647 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.00607658 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00606367 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 0.00600876 |
| CHI3L2 | chitinase 3-like 2 | 0.00600617 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00591834 |
| SDC4 | syndecan 4 | 0.00581208 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0057041 |
| FZD5 | frizzled class receptor 5 | 0.00564037 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00563795 |
| KRT18 | keratin 18, type I | 0.00560959 |
| COPS7A | COP9 signalosome subunit 7A | 0.00555937 |
| ELN | elastin | 0.00541423 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00534329 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00533559 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00532508 |
| C1R | complement component 1, r subcomponent | 0.00528364 |
| MYBPC1 | myosin binding protein C, slow type | 0.00527431 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00523099 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00518447 |
| TMEM106B | transmembrane protein 106B | 0.00514101 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00511606 |
| ASPN | asporin | 0.00505843 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 0.00505278 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00503172 |
| GLUL | glutamate-ammonia ligase | 0.00500434 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.00499627 |
| CHN1 | chimerin 1 | 0.00497514 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.00496617 |
| WDR61 | WD repeat domain 61 | 0.00495249 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00494233 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00493515 |
| TMEM260 | transmembrane protein 260 | 0.00489795 |
| JAG1 | jagged 1 | 0.00489784 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00488619 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00488522 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | 0.00488018 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00487665 |
| EPCAM | epithelial cell adhesion molecule | 0.00486996 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00484493 |
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | 0.00482906 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.00482751 |
| SNX13 | sorting nexin 13 | 0.00482546 |
| A2M | alpha-2-macroglobulin | 0.00478579 |
| NKX3-1 | NK3 homeobox 1 | 0.00474933 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00474734 |
| TSPAN13 | tetraspanin 13 | 0.00474527 |
| NPTN | neuroplastin | 0.00473919 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00471573 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00469153 |
| CNN3 | calponin 3, acidic | 0.00468575 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00466865 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00465195 |
| OLFM1 | olfactomedin 1 | 0.0046395 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00463776 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.00461703 |
| BID | BH3 interacting domain death agonist | 0.00461599 |
| INSIG1 | insulin induced gene 1 | 0.00459494 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00458795 |
| FRZB | frizzled-related protein | 0.00457962 |
| DES | desmin | 0.00457813 |
| AK4 | adenylate kinase 4 | 0.00456381 |
| PCDH17 | protocadherin 17 | 0.00454449 |
| FBXO3 | F-box protein 3 | 0.00454066 |
| CES1 | carboxylesterase 1 | 0.00452699 |
| CD302 | CD302 molecule | 0.00452139 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.00449982 |
| CFD | complement factor D (adipsin) | 0.00447524 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | 0.00446546 |
| EPHA4 | EPH receptor A4 | 0.0044623 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00444845 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00442853 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00441507 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00438618 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00437095 |
| ACKR3 | atypical chemokine receptor 3 | 0.00436114 |
| APOB | apolipoprotein B | 0.00434049 |
| NDRG2 | NDRG family member 2 | 0.00433486 |
| GPM6B | glycoprotein M6B | 0.00430331 |
| TMOD1 | tropomodulin 1 | 0.004288 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.0042814 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00426685 |
| LTF | lactotransferrin | 0.00426013 |
| NINJ2 | ninjurin 2 | 0.0042541 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | 0.00425177 |
| CHRDL1 | chordin-like 1 | 0.00425053 |
| ASPH | aspartate beta-hydroxylase | 0.00424836 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.00423369 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00421779 |
| ACD | adrenocortical dysplasia homolog (mouse) | 0.00420802 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00419485 |
| ALAS2 | 5'-aminolevulinate synthase 2 | 0.0041882 |
| NEO1 | neogenin 1 | 0.004172 |
| MALL | mal, T-cell differentiation protein-like | 0.00414147 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00413338 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00411643 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | 0.00409191 |
| WTAP | Wilms tumor 1 associated protein | 0.00408778 |
| OLFM4 | olfactomedin 4 | 0.0040846 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00406284 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.00406 |
| TSPO | translocator protein (18kDa) | 0.0040539 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00405193 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00404888 |
| STK39 | serine threonine kinase 39 | 0.00403851 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00403054 |
| MCOLN1 | mucolipin 1 | 0.00402947 |
| S100A4 | S100 calcium binding protein A4 | 0.00401588 |
| TRMT5 | tRNA methyltransferase 5 | 0.00400667 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00399727 |
| FABP7 | fatty acid binding protein 7, brain | 0.00399077 |
| ANXA1 | annexin A1 | 0.00398508 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00396621 |
| MGP | matrix Gla protein | 0.00394765 |
| CLGN | calmegin | 0.00393239 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00393034 |
| MLF1 | myeloid leukemia factor 1 | 0.00392585 |
| KLHL21 | kelch-like family member 21 | 0.00391969 |
| PENK | proenkephalin | 0.00391774 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00391701 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00390495 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00390219 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00389226 |
| MSX1 | msh homeobox 1 | 0.00387898 |
| CFB | complement factor B | 0.00387503 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00386952 |
| FASN | fatty acid synthase | 0.00386692 |
| VWF | von Willebrand factor | 0.00384854 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.0038484 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00383735 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | 0.00383716 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00383444 |
| ODC1 | ornithine decarboxylase 1 | 0.00382407 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.00381853 |
| RBM47 | RNA binding motif protein 47 | 0.00381724 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | 0.00381072 |
| H1-2 | H1.2 linker histone, cluster member | 0.00380623 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.00380408 |
| PTN | pleiotrophin | 0.00379307 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.00378342 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00378277 |
| UNC50 | unc-50 homolog (C. elegans) | 0.0037819 |
| TNS1 | tensin 1 | 0.00378166 |
| LYST | lysosomal trafficking regulator | 0.00377843 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00377375 |
| DSE | dermatan sulfate epimerase | 0.00376673 |
| RYR1 | ryanodine receptor 1 (skeletal) | 0.00375837 |
| CTSK | cathepsin K | 0.00375465 |
| SRP9 | signal recognition particle 9kDa | 0.00375275 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.00374939 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.00374479 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | 0.00373835 |
| PANK2 | pantothenate kinase 2 | 0.00373776 |
| RYBP | RING1 and YY1 binding protein | 0.00373577 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.00373317 |
| GSTT2 | glutathione S-transferase theta 2 (gene/pseudogene) | 0.00372493 |
| ARMC1 | armadillo repeat containing 1 | 0.00372249 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.0037111 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00369916 |
| FOXF1 | forkhead box F1 | 0.00369786 |
| RNF141 | ring finger protein 141 | 0.00368967 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00368695 |
| CENPE | centromere protein E, 312kDa | 0.00368332 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.00368223 |
| LUM | lumican | 0.00368125 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00367935 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00367541 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.0036734 |
| NIPSNAP2 | nipsnap homolog 2 | 0.00367183 |
| TFRC | transferrin receptor | 0.00364573 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00363867 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00363755 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | 0.00362407 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00362207 |
| GMPR | guanosine monophosphate reductase | 0.00361776 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00360875 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 0.00360045 |
| KHNYN | KH and NYN domain containing | 0.00359774 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | 0.0035955 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.00358948 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00358846 |
| MICU2 | mitochondrial calcium uptake 2 | 0.0035851 |
| AHSP | alpha hemoglobin stabilizing protein | 0.00358326 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.00358231 |
| CD46 | CD46 molecule, complement regulatory protein | 0.00357824 |
| TSPAN7 | tetraspanin 7 | 0.0035662 |
| CTSV | cathepsin V | 0.0035621 |
| IL1RN | interleukin 1 receptor antagonist | 0.00355344 |
| SYNM | synemin, intermediate filament protein | 0.00355035 |
| CHEK2 | checkpoint kinase 2 | 0.00354479 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00353162 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00352835 |
| CHERP | calcium homeostasis endoplasmic reticulum protein | 0.00352667 |
| DLX5 | distal-less homeobox 5 | 0.00352099 |
| KRT17 | keratin 17, type I | 0.00351702 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00350058 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00349576 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00349358 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 0.00349348 |
| SORD | sorbitol dehydrogenase | 0.0034919 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00348836 |
| ACTB | actin, beta | 0.00347643 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00347594 |
| ANXA5 | annexin A5 | 0.00347425 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.00347388 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.00347028 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00346939 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00346508 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00346316 |
| OSBPL11 | oxysterol binding protein-like 11 | 0.00346056 |
| MARCH2 | membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase | 0.00345772 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00344469 |
| HAT1 | histone acetyltransferase 1 | 0.00344457 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.0034424 |
| EP300 | E1A binding protein p300 | 0.00343528 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00342778 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00342661 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00341847 |
| PPAP2A | phosphatidic acid phosphatase type 2A | 0.00341835 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00341612 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | -0.00927917 |
| SRGN | serglycin | -0.00917506 |
| XIC | X chromosome inactivation center | -0.00840405 |
| MAL | mal, T-cell differentiation protein | -0.0084033 |
| RGS4 | regulator of G-protein signaling 4 | -0.00808427 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00800587 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00796068 |
| CA12 | carbonic anhydrase XII | -0.00766351 |
| CTSD | cathepsin D | -0.00694912 |
| MVP | major vault protein | -0.00685432 |
| CYTIP | cytohesin 1 interacting protein | -0.00637756 |
| GMFG | glia maturation factor, gamma | -0.00637291 |
| EVI2A | ecotropic viral integration site 2A | -0.00618764 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00604212 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00604097 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00603492 |
| KLF6 | Kruppel-like factor 6 | -0.00603354 |
| MT1X | metallothionein 1X | -0.00599708 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.0059614 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00584743 |
| TFF1 | trefoil factor 1 | -0.00584454 |
| THBS1 | thrombospondin 1 | -0.00582375 |
| HOPX | HOP homeobox | -0.00581516 |
| MT2A | metallothionein 2A | -0.00575 |
| S100A9 | S100 calcium binding protein A9 | -0.00573441 |
| MT1H | metallothionein 1H | -0.00570143 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00556726 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.00553106 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00544732 |
| WDR7 | WD repeat domain 7 | -0.00540126 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00532218 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00530979 |
| MATN2 | matrilin 2 | -0.00529957 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00525459 |
| SMAD3 | SMAD family member 3 | -0.00524826 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | -0.00522329 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00517878 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0051718 |
| S100A8 | S100 calcium binding protein A8 | -0.00516599 |
| APOD | apolipoprotein D | -0.00515942 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00515204 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00511746 |
| SIX2 | SIX homeobox 2 | -0.00510571 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00507769 |
| MMP1 | matrix metallopeptidase 1 | -0.00504367 |
| MT1E | metallothionein 1E | -0.00504306 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0049458 |
| VNN1 | vanin 1 | -0.00494521 |
| RAI14 | retinoic acid induced 14 | -0.00493093 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00486064 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | -0.00485851 |
| SCG5 | secretogranin V | -0.00485534 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00479515 |
| F2R | coagulation factor II (thrombin) receptor | -0.004775 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00476919 |
| ACVR1B | activin A receptor, type IB | -0.00476505 |
| RTN3 | reticulon 3 | -0.00476499 |
| PXDN | peroxidasin | -0.00476246 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00475061 |
| IL18 | interleukin 18 | -0.00474979 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | -0.00473869 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | -0.00473332 |
| STMN2 | stathmin 2 | -0.00472371 |
| CDC25A | cell division cycle 25A | -0.00471317 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -0.0047027 |
| CHEK1 | checkpoint kinase 1 | -0.00469325 |
| NID2 | nidogen 2 (osteonidogen) | -0.00469186 |
| ITK | IL2-inducible T-cell kinase | -0.00466952 |
| DOCK10 | dedicator of cytokinesis 10 | -0.00463343 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | -0.00463119 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0046231 |
| AOX1 | aldehyde oxidase 1 | -0.00460872 |
| COLEC12 | collectin sub-family member 12 | -0.0045834 |
| FSD1 | fibronectin type III and SPRY domain containing 1 | -0.00456496 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00454529 |
| S100A11 | S100 calcium binding protein A11 | -0.00454194 |
| LAMB1 | laminin, beta 1 | -0.00452934 |
| MMP12 | matrix metallopeptidase 12 | -0.00452277 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00450591 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00449911 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00449286 |
| BAX | BCL2-associated X protein | -0.00447959 |
| KLK8 | kallikrein-related peptidase 8 | -0.00444586 |
| FCGBP | Fc fragment of IgG binding protein | -0.00443471 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -0.00443168 |
| RPS27L | ribosomal protein S27-like | -0.0044272 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.00437104 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00436859 |
| PFKP | phosphofructokinase, platelet | -0.00435682 |
| THBS2 | thrombospondin 2 | -0.00435619 |
| CTSS | cathepsin S | -0.00435616 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00435577 |
| JAM3 | junctional adhesion molecule 3 | -0.00435389 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00432413 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00432407 |
| EFNA5 | ephrin-A5 | -0.00429578 |
| TUBB2B | tubulin, beta 2B class IIb | -0.0042926 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00426744 |
| SLITRK5 | SLIT and NTRK-like family, member 5 | -0.00426599 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00424832 |
| PRKCA | protein kinase C, alpha | -0.0042223 |
| TXNIP | thioredoxin interacting protein | -0.0042202 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00421528 |
| GPER1 | G protein-coupled estrogen receptor 1 | -0.00420848 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.0041863 |
| MEG3 | maternally expressed 3 (non-protein coding) | -0.00418405 |
| NEFM | neurofilament, medium polypeptide | -0.00418156 |
| FMO1 | flavin containing monooxygenase 1 | -0.00416472 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00415484 |
| AHNAK | AHNAK nucleoprotein | -0.00413047 |
| TLR4 | toll-like receptor 4 | -0.00412521 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00410265 |
| NCALD | neurocalcin delta | -0.00409051 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00409024 |
| BMERB1 | bMERB domain containing 1 | -0.00408322 |
| RGS2 | regulator of G-protein signaling 2 | -0.00406134 |
| MT1G | metallothionein 1G | -0.00406116 |
| STK10 | serine/threonine kinase 10 | -0.00404782 |
| TXN | thioredoxin | -0.00404292 |
| NNAT | neuronatin | -0.00402925 |
| S100A14 | S100 calcium binding protein A14 | -0.00402663 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.00401881 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00401169 |
| CTSC | cathepsin C | -0.00401056 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00400337 |
| COLEC11 | collectin sub-family member 11 | -0.00397712 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00397619 |
| RHCG | Rh family, C glycoprotein | -0.0039521 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00394497 |
| PCLAF | PCNA clamp associated factor | -0.00394055 |
| CTSG | cathepsin G | -0.00393782 |
| PRPH | peripherin | -0.00392699 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0039252 |
| HOXB6 | homeobox B6 | -0.0039247 |
| NVL | nuclear VCP-like | -0.00391969 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.00390885 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.00390284 |
| THEMIS2 | thymocyte selection associated family member 2 | -0.00389427 |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | -0.00388565 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00388103 |
| CCNA2 | cyclin A2 | -0.00387783 |
| VCAN | versican | -0.00387165 |
| ECM1 | extracellular matrix protein 1 | -0.00386534 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -0.00386517 |
| PFKM | phosphofructokinase, muscle | -0.00385905 |
| ETHE1 | ethylmalonic encephalopathy 1 | -0.00385078 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0038465 |
| VPREB1 | pre-B lymphocyte 1 | -0.00384598 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.00384385 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.00384198 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00381759 |
| GDF15 | growth differentiation factor 15 | -0.00381611 |
| GAP43 | growth associated protein 43 | -0.00381373 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00380799 |
| CCN2 | cellular communication network factor 2 | -0.00379781 |
| ADIRF | adipogenesis regulatory factor | -0.00379655 |
| MELK | maternal embryonic leucine zipper kinase | -0.0037836 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.00378107 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.00376142 |
| TFEC | transcription factor EC | -0.00376118 |
| TYMS | thymidylate synthetase | -0.00375168 |
| STMN4 | stathmin-like 4 | -0.00374522 |
| PSAP | prosaposin | -0.00372141 |
| NOTCH1 | notch 1 | -0.00372102 |
| ARSL | arylsulfatase L | -0.00371943 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.00371814 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00370827 |
| CDC123 | cell division cycle 123 | -0.00369586 |
| GPSM3 | G-protein signaling modulator 3 | -0.00369396 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -0.00368624 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00368496 |
| CD14 | CD14 molecule | -0.00366777 |
| ANXA6 | annexin A6 | -0.00365625 |
| SPATA20 | spermatogenesis associated 20 | -0.00364866 |
| KLHDC8A | kelch domain containing 8A | -0.00364093 |
| PARVA | parvin, alpha | -0.00363587 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00363504 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00362873 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.00362374 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00362135 |
| DGKA | diacylglycerol kinase, alpha 80kDa | -0.00361832 |
| COG7 | component of oligomeric golgi complex 7 | -0.00361198 |
| PROM1 | prominin 1 | -0.00361188 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.00361099 |
| MYOF | myoferlin | -0.00360648 |
| KLK7 | kallikrein-related peptidase 7 | -0.00360471 |
| PUDP | pseudouridine 5'-phosphatase | -0.00358967 |
| MBD2 | methyl-CpG binding domain protein 2 | -0.0035762 |
| LAMA4 | laminin, alpha 4 | -0.00357541 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0035588 |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | -0.00355606 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00355503 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -0.00354546 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.00354535 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00354009 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00353823 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00353657 |
| AIM2 | absent in melanoma 2 | -0.00352882 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00352734 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.00352453 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00352021 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00351574 |
| PRDX1 | peroxiredoxin 1 | -0.00351369 |
| NDRG1 | N-myc downstream regulated 1 | -0.00350783 |
| FAIM | Fas apoptotic inhibitory molecule | -0.00349822 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 | -0.0034961 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.00348826 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -0.00348318 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00347503 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00346694 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.00346361 |
| PLK1 | polo-like kinase 1 | -0.00345409 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | -0.00345336 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00344247 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00344124 |
| ESR1 | estrogen receptor 1 | -0.00343946 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00343201 |
| MRC2 | mannose receptor, C type 2 | -0.00342931 |
| FDX1 | ferredoxin 1 | -0.00342421 |
| ELANE | elastase, neutrophil expressed | -0.00342174 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | -0.00341225 |
| SELPLG | selectin P ligand | -0.00341157 |
| FA2H | fatty acid 2-hydroxylase | -0.00340473 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00340461 |
| NAV3 | neuron navigator 3 | -0.00340153 |
| CDHR1 | cadherin-related family member 1 | -0.00340118 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.0033919 |
| IER5 | immediate early response 5 | -0.00339057 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | -0.0033904 |
| ASPA | aspartoacylase | -0.00338644 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 | -0.00337677 |
| TENM3 | teneurin transmembrane protein 3 | -0.00337425 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00337289 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.00336777 |
| TUFT1 | tuftelin 1 | -0.00336718 |
| ANKRD28 | ankyrin repeat domain 28 | -0.00336506 |
| GAB2 | GRB2-associated binding protein 2 | -0.00335281 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.00333926 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | -0.00333692 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -0.00333077 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.00332941 |
| SCRIB | scribbled planar cell polarity protein | -0.00332844 |
| FHOD3 | formin homology 2 domain containing 3 | -0.0033204 |
| EDN1 | endothelin 1 | -0.00331793 |
| MOBP | myelin-associated oligodendrocyte basic protein | -0.00331349 |
| MT1F | metallothionein 1F | -0.00331165 |
| DCX | doublecortin | -0.00330669 |
| IL2RG | interleukin 2 receptor, gamma | -0.00330352 |
| IL1B | interleukin 1, beta | -0.00329924 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | -0.00329716 |
