ING3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description inhibitor of growth family, member 3|The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 54556)
External Link http://www.ncbi.nlm.nih.gov/gene/54556
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Genes

58 interacting proteins for ING3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTB actin, beta
ACTL6A actin-like 6A
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
APP amyloid beta (A4) precursor protein
BRD8 bromodomain containing 8
CUL1 cullin 1
DMAP1 DNA methyltransferase 1 associated protein 1
EAF1 ELL associated factor 1
ELAVL1 ELAV like RNA binding protein 1
EP400 E1A binding protein p400
EPC1 enhancer of polycomb homolog 1 (Drosophila)
EPC2 enhancer of polycomb homolog 2 (Drosophila)
ERVK-19 endogenous retrovirus group K, member 19
FBXO25 F-box protein 25
GATS GATS, stromal antigen 3 opposite strand
H2AFZ H2A histone family, member Z
HIST1H2AA histone cluster 1, H2aa
HIST1H2AB histone cluster 1, H2ab
HIST1H2AC histone cluster 1, H2ac
HIST1H2AD histone cluster 1, H2ad
HIST1H2AH histone cluster 1, H2ah
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H4F histone cluster 1, H4f
HIST2H2AA4 histone cluster 2, H2aa4
HIST2H2AB histone cluster 2, H2ab
HIST2H2AC histone cluster 2, H2ac
HIST3H2A histone cluster 3, H2a
HNF4A hepatocyte nuclear factor 4, alpha
HSPA1B heat shock 70kDa protein 1B
INO80 INO80 complex subunit
INO80B INO80 complex subunit B
INO80C INO80 complex subunit C
INO80E INO80 complex subunit E
KAT5 K(lysine) acetyltransferase 5
MEAF6 MYST/Esa1-associated factor 6
MORF4L1 mortality factor 4 like 1
MORF4L2 mortality factor 4 like 2
MRGBP MRG/MORF4L binding protein
NFRKB nuclear factor related to kappaB binding protein
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
PLSCR4 phospholipid scramblase 4
RBX1 ring-box 1, E3 ubiquitin protein ligase
RSL1D1 ribosomal L1 domain containing 1
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SRCAP Snf2-related CREBBP activator protein
TCF3 transcription factor 3
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TRRAP transformation/transcription domain-associated protein
UBC ubiquitin C
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
YEATS4 YEATS domain containing 4
ZNHIT1 zinc finger, HIT-type containing 1