| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | inositol polyphosphate-5-phosphatase, 145kDa|This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014] (NCBI Entrez Gene Database, 3635) |
| External Link | https://ncbi.nlm.nih.gov/gene/3635 |
| Similar Terms | |
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499 genes differentially expressed following the INPP5D gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.019254 |
| PRAME | preferentially expressed antigen in melanoma | 0.0135407 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.0134013 |
| S100A9 | S100 calcium binding protein A9 | 0.0123787 |
| NTS | neurotensin | 0.0121791 |
| S100A7 | S100 calcium binding protein A7 | 0.0116353 |
| EMX2 | empty spiracles homeobox 2 | 0.0114452 |
| WT1 | Wilms tumor 1 | 0.0109494 |
| S100A8 | S100 calcium binding protein A8 | 0.0109369 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0106323 |
| XIC | X chromosome inactivation center | 0.0102675 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00992015 |
| TNC | tenascin C | 0.00978557 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00974435 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00968645 |
| AK4 | adenylate kinase 4 | 0.00956679 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00952084 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00936438 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00927313 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.0092022 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0089266 |
| TRIM16 | tripartite motif containing 16 | 0.00874702 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00868037 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00854347 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00853035 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0084642 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00846253 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00841359 |
| RCAN1 | regulator of calcineurin 1 | 0.00838636 |
| BCL2A1 | BCL2-related protein A1 | 0.00833733 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00830991 |
| CD69 | CD69 molecule | 0.00830861 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00825056 |
| IL15 | interleukin 15 | 0.00809936 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00809242 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00806704 |
| TPM2 | tropomyosin 2 (beta) | 0.00803396 |
| PITX3 | paired-like homeodomain 3 | 0.0079323 |
| GCH1 | GTP cyclohydrolase 1 | 0.00783136 |
| MARCKSL1 | MARCKS-like 1 | 0.00766714 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00765312 |
| TBX3 | T-box 3 | 0.00763205 |
| IER5 | immediate early response 5 | 0.00748803 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00747109 |
| CLEC11A | C-type lectin domain family 11, member A | 0.0074702 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00745242 |
| CA12 | carbonic anhydrase XII | 0.00744673 |
| CD1E | CD1e molecule | 0.00744168 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00740347 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00729705 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00724109 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.007199 |
| MAGEA3 | melanoma antigen family A3 | 0.00708846 |
| ESR1 | estrogen receptor 1 | 0.00705806 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00702195 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00698897 |
| MDFIC | MyoD family inhibitor domain containing | 0.00698548 |
| IRF1 | interferon regulatory factor 1 | 0.0069284 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00692299 |
| FZD5 | frizzled class receptor 5 | 0.00686629 |
| S100A12 | S100 calcium binding protein A12 | 0.00686581 |
| FLOT1 | flotillin 1 | 0.00685289 |
| WBP5 | WW domain binding protein 5 | 0.00679141 |
| MREG | melanoregulin | 0.00678598 |
| FERMT1 | fermitin family member 1 | 0.0067759 |
| AHCY | adenosylhomocysteinase | 0.0066842 |
| KLK10 | kallikrein-related peptidase 10 | 0.00667025 |
| MLPH | melanophilin | 0.00666251 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0066298 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00662938 |
| PRKD1 | protein kinase D1 | 0.00659529 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00658827 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00653068 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00649998 |
| AOC1 | amine oxidase, copper containing 1 | 0.00647239 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00645212 |
| ELANE | elastase, neutrophil expressed | 0.0064187 |
| RPL36 | ribosomal protein L36 | 0.00641415 |
| CLIC5 | chloride intracellular channel 5 | 0.00640868 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00639113 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00636975 |
| MX2 | MX dynamin-like GTPase 2 | 0.00636463 |
| NSG1 | neuron specific gene family member 1 | 0.00635618 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.0063498 |
| MMP11 | matrix metallopeptidase 11 | 0.00633555 |
| MME | membrane metallo-endopeptidase | 0.00633145 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00631813 |
| EHF | ets homologous factor | 0.00631258 |
| CDK14 | cyclin-dependent kinase 14 | 0.00627633 |
| LTA4H | leukotriene A4 hydrolase | 0.00625644 |
| VEGFC | vascular endothelial growth factor C | 0.00620651 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00620592 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00619937 |
| PLAT | plasminogen activator, tissue | 0.00617821 |
| PLA1A | phospholipase A1 member A | 0.00617496 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00616876 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00616364 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00614674 |
| CDC25B | cell division cycle 25B | 0.00613362 |
| PNMA8A | PNMA family member 8A | 0.00603506 |
| MMP10 | matrix metallopeptidase 10 | 0.00602045 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00601898 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00599858 |
| PRTN3 | proteinase 3 | 0.00598618 |
| OXTR | oxytocin receptor | 0.00597379 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 0.00597292 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0059458 |
| CD200 | CD200 molecule | 0.00594297 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.00594099 |
| LBH | limb bud and heart development | 0.005938 |
| CERS6 | ceramide synthase 6 | 0.00592235 |
| PMEL | premelanosome protein | 0.00590929 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00588702 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | 0.00585616 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00585461 |
| HMGA1 | high mobility group AT-hook 1 | 0.0058383 |
| IL32 | interleukin 32 | 0.00583644 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00580223 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00580142 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.0057928 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00577597 |
| BTG3 | BTG family, member 3 | 0.00575536 |
| MPO | myeloperoxidase | 0.00574227 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00573064 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.00572632 |
| IQCG | IQ motif containing G | 0.00570849 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.00570252 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | 0.0057016 |
| GATA6 | GATA binding protein 6 | 0.00569147 |
| RPL14 | ribosomal protein L14 | 0.00568479 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00567538 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0056652 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 0.00565709 |
| ASRGL1 | asparaginase like 1 | 0.00565328 |
| SPART | spartin | 0.00564265 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00563779 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 | 0.00563739 |
| SCEL | sciellin | 0.00563643 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 0.00562242 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00562192 |
| TRAK2 | trafficking protein, kinesin binding 2 | 0.00562174 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00560689 |
| CST7 | cystatin F (leukocystatin) | 0.00560052 |
| TMEM14B | transmembrane protein 14B | 0.00558145 |
| APOC1 | apolipoprotein C-I | 0.00557404 |
| ZWINT | ZW10 interacting kinetochore protein | 0.00555394 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00555364 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00552908 |
| HMG20B | high mobility group 20B | 0.00552447 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.005522 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.00552079 |
| CYB561 | cytochrome b561 | 0.00551835 |
| TFEC | transcription factor EC | 0.00549904 |
| TYR | tyrosinase | 0.00547348 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00546604 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00544326 |
| CD48 | CD48 molecule | 0.00544237 |
| CD1C | CD1c molecule | 0.00543802 |
| RGS10 | regulator of G-protein signaling 10 | 0.00542898 |
| RGS13 | regulator of G-protein signaling 13 | 0.00541802 |
| DUSP2 | dual specificity phosphatase 2 | 0.00540857 |
| GPR161 | G protein-coupled receptor 161 | 0.00540134 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00539932 |
| HOPX | HOP homeobox | 0.00539094 |
| LPXN | leupaxin | 0.00537827 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00537618 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.005365 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.00533506 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00533397 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00531799 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00529366 |
| LY75 | lymphocyte antigen 75 | 0.00528814 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 0.00527551 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00527528 |
| RHCG | Rh family, C glycoprotein | 0.00527417 |
| RPL29 | ribosomal protein L29 | 0.0052688 |
| IER2 | immediate early response 2 | 0.00524936 |
| SELL | selectin L | 0.0052362 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00521942 |
| TSPO | translocator protein (18kDa) | 0.00520794 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00519896 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00519803 |
| HPF1 | histone PARylation factor 1 | 0.00515667 |
| ADA | adenosine deaminase | 0.00515528 |
| LOC730101 | uncharacterized LOC730101 | 0.00515184 |
| TRAF1 | TNF receptor-associated factor 1 | 0.00514748 |
| RPS5 | ribosomal protein S5 | 0.00514535 |
| GIPC2 | GIPC PDZ domain containing family, member 2 | 0.00513153 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00512589 |
| FBXO11 | F-box protein 11 | 0.00511663 |
| TSPOAP1 | TSPO associated protein 1 | 0.00511275 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00510803 |
| BAK1 | BCL2-antagonist/killer 1 | 0.00510514 |
| VCAN | versican | 0.00508223 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00506935 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00502731 |
| CA9 | carbonic anhydrase IX | 0.00502282 |
| ITK | IL2-inducible T-cell kinase | 0.00501489 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0050123 |
| SPRR1B | small proline-rich protein 1B | 0.00500612 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.00500353 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00499885 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00499565 |
| HLTF | helicase-like transcription factor | 0.00496138 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.00494764 |
| OBSL1 | obscurin-like 1 | 0.0049451 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.0049368 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.00492914 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00492673 |
| ZNF337 | zinc finger protein 337 | 0.0049213 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00487203 |
| RAB38 | RAB38, member RAS oncogene family | 0.00485293 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00485287 |
| CLIC3 | chloride intracellular channel 3 | 0.00484719 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00483868 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00483686 |
| COG4 | component of oligomeric golgi complex 4 | 0.00483305 |
| PODXL | podocalyxin-like | 0.00482192 |
| PCNA | proliferating cell nuclear antigen | 0.00481991 |
| NVL | nuclear VCP-like | 0.00480056 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 0.00479855 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00479569 |
| PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | 0.00479547 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0047855 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 0.00478233 |
| LOXL1 | lysyl oxidase-like 1 | 0.00477404 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00477325 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00476149 |
| GSAP | gamma-secretase activating protein | 0.00476139 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | 0.00475608 |
| NPR3 | natriuretic peptide receptor 3 | 0.00474716 |
| SULF1 | sulfatase 1 | 0.00474606 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00474464 |
| CD83 | CD83 molecule | 0.0047394 |
| IL1RN | interleukin 1 receptor antagonist | 0.00472627 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00472375 |
| RGS2 | regulator of G-protein signaling 2 | 0.00472209 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00471002 |
| MEX3D | mex-3 RNA binding family member D | 0.00469994 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.00469229 |
| KRT81 | keratin 81, type II | 0.00467873 |
| ZNF133 | zinc finger protein 133 | 0.00467135 |
| LIAS | lipoic acid synthetase | 0.0046703 |
| PCGF2 | polycomb group ring finger 2 | 0.00466337 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00466004 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | 0.00465395 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00465344 |
| ETHE1 | ethylmalonic encephalopathy 1 | 0.00464005 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00463983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADI1 | acireductone dioxygenase 1 | -0.0181017 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0148625 |
| SIRT3 | sirtuin 3 | -0.0140565 |
| ACD | adrenocortical dysplasia homolog (mouse) | -0.0121708 |
| REEP1 | receptor accessory protein 1 | -0.0117804 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0114581 |
| WASHC4 | WASH complex subunit 4 | -0.0114309 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.011416 |
| MGLL | monoglyceride lipase | -0.0113201 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.0108322 |
| SC5D | sterol-C5-desaturase | -0.0106926 |
| A2M | alpha-2-macroglobulin | -0.0105635 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0104963 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | -0.0101798 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0100368 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.0100033 |
| SDC2 | syndecan 2 | -0.0099757 |
| STK10 | serine/threonine kinase 10 | -0.00983935 |
| CADM1 | cell adhesion molecule 1 | -0.00962975 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00936259 |
| BEX1 | brain expressed, X-linked 1 | -0.00926788 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00924205 |
| SYT1 | synaptotagmin I | -0.00910685 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00910346 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00896986 |
| MAP7 | microtubule-associated protein 7 | -0.0089647 |
| NPTN | neuroplastin | -0.00887419 |
| LYPLA1 | lysophospholipase I | -0.00883445 |
| RHOB | ras homolog family member B | -0.00882055 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.0087344 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00871582 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00867402 |
| APOD | apolipoprotein D | -0.00862522 |
| S100P | S100 calcium binding protein P | -0.00848165 |
| GNAS | GNAS complex locus | -0.0083758 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00831027 |
| GPC3 | glypican 3 | -0.00824466 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00822598 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0082045 |
| MGP | matrix Gla protein | -0.00818366 |
| LTF | lactotransferrin | -0.00795602 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | -0.00793439 |
| GPM6B | glycoprotein M6B | -0.00789191 |
| CD163 | CD163 molecule | -0.0078827 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | -0.00788004 |
| CPD | carboxypeptidase D | -0.00786802 |
| PCP4 | Purkinje cell protein 4 | -0.00782334 |
| ABHD3 | abhydrolase domain containing 3 | -0.00779751 |
| SERINC5 | serine incorporator 5 | -0.00779647 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00771708 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00766708 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00765824 |
| HYOU1 | hypoxia up-regulated 1 | -0.00765631 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00764923 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00764843 |
| NEFH | neurofilament, heavy polypeptide | -0.00758295 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00756192 |
| METTL7A | methyltransferase like 7A | -0.007535 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00751431 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00742406 |
| FRZB | frizzled-related protein | -0.00740538 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.0074021 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00737935 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00736663 |
| PENK | proenkephalin | -0.00731559 |
| SETBP1 | SET binding protein 1 | -0.00731368 |
| CPE | carboxypeptidase E | -0.00725494 |
| THBS4 | thrombospondin 4 | -0.00721708 |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | -0.00720225 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 | -0.00713356 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00710471 |
| RCAN2 | regulator of calcineurin 2 | -0.0070813 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00708088 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.00700045 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00697323 |
| CD14 | CD14 molecule | -0.00692117 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00688492 |
| COBL | cordon-bleu WH2 repeat protein | -0.00686836 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.006868 |
| GAS7 | growth arrest-specific 7 | -0.00681111 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00677378 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.00675463 |
| LAMB1 | laminin, beta 1 | -0.00670053 |
| PERP | PERP, TP53 apoptosis effector | -0.00667401 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00666752 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | -0.00664165 |
| GPX3 | glutathione peroxidase 3 | -0.00662052 |
| CDO1 | cysteine dioxygenase type 1 | -0.00659842 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | -0.00659827 |
| IL17RB | interleukin 17 receptor B | -0.00656538 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00656172 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00654223 |
| NPTX1 | neuronal pentraxin I | -0.00651916 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00651748 |
| FKBP5 | FK506 binding protein 5 | -0.00650921 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00649942 |
| TRIM29 | tripartite motif containing 29 | -0.00649867 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00649554 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | -0.00649446 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00648855 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00647444 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.0064473 |
| DCLK1 | doublecortin-like kinase 1 | -0.00644483 |
| H2AFV | H2A histone family, member V | -0.00644379 |
| L1CAM | L1 cell adhesion molecule | -0.00640317 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.00639944 |
| CCNB1 | cyclin B1 | -0.00636005 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00635774 |
| STMN2 | stathmin 2 | -0.00634779 |
| SIK3 | SIK family kinase 3 | -0.00634436 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00633805 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00633426 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00629879 |
| CHGB | chromogranin B | -0.00619014 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00618478 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00617549 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | -0.00615808 |
| RDX | radixin | -0.00614143 |
| RAB8A | RAB8A, member RAS oncogene family | -0.00614059 |
| RTN4 | reticulon 4 | -0.00612413 |
| ZW10 | zw10 kinetochore protein | -0.00611974 |
| CERK | ceramide kinase | -0.00611887 |
| CDA | cytidine deaminase | -0.00611845 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | -0.00611387 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00611078 |
| PCDH9 | protocadherin 9 | -0.00609579 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00608764 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00607578 |
| MMP2 | matrix metallopeptidase 2 | -0.00606521 |
| COL4A2 | collagen, type IV, alpha 2 | -0.00604509 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.0060326 |
| NEFM | neurofilament, medium polypeptide | -0.00601077 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00600972 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | -0.00600691 |
| GSN | gelsolin | -0.00599866 |
| ELN | elastin | -0.00597906 |
| CP | ceruloplasmin (ferroxidase) | -0.00597603 |
| RTN1 | reticulon 1 | -0.00595529 |
| COLEC12 | collectin sub-family member 12 | -0.00595023 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00594979 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0059465 |
| MCOLN1 | mucolipin 1 | -0.00593845 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.00593728 |
| STC2 | stanniocalcin 2 | -0.00593043 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00591268 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.00591205 |
| CLU | clusterin | -0.00590145 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00590006 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00589344 |
| FN1 | fibronectin 1 | -0.00587918 |
| RTN2 | reticulon 2 | -0.00583992 |
| NIT1 | nitrilase 1 | -0.00583152 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.0058246 |
| MAP1B | microtubule-associated protein 1B | -0.00581702 |
| GSE1 | Gse1 coiled-coil protein | -0.00580536 |
| NPTX2 | neuronal pentraxin II | -0.00579462 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00579363 |
| HMP19 | HMP19 protein | -0.00577491 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00575926 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00574792 |
| VCL | vinculin | -0.00573806 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0057319 |
| IL6ST | interleukin 6 signal transducer | -0.00572125 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.00571629 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00570881 |
| STK39 | serine threonine kinase 39 | -0.00569469 |
| EXPH5 | exophilin 5 | -0.00569447 |
| TRIM8 | tripartite motif containing 8 | -0.00566927 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00566105 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00564174 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00563863 |
| NFASC | neurofascin | -0.00563648 |
| GLUL | glutamate-ammonia ligase | -0.00562889 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00562478 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | -0.00562097 |
| TULP3 | tubby like protein 3 | -0.00560924 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.0055691 |
| SFTPA2 | surfactant protein A2 | -0.00556248 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | -0.00555052 |
| CD209 | CD209 molecule | -0.0055491 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00553898 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00553676 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00552907 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00552625 |
| CTSA | cathepsin A | -0.00552106 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00552078 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00551366 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.00548859 |
| CES1 | carboxylesterase 1 | -0.00545469 |
| CFB | complement factor B | -0.00545086 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00542357 |
| CCL13 | chemokine (C-C motif) ligand 13 | -0.00541624 |
| ITGA8 | integrin, alpha 8 | -0.00541593 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.00540768 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00540614 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00540465 |
| SECISBP2L | SECIS binding protein 2-like | -0.00539615 |
| SDHAP1 | succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 | -0.00539131 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00537902 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.00537146 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.00535692 |
| THBS1 | thrombospondin 1 | -0.00535052 |
| CRTC3 | CREB regulated transcription coactivator 3 | -0.00533566 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00533536 |
| TAGLN | transgelin | -0.00532646 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00532471 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00531879 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00531405 |
| PGBD5 | piggyBac transposable element derived 5 | -0.00531076 |
| SPP1 | secreted phosphoprotein 1 | -0.00529384 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00528168 |
| FADS3 | fatty acid desaturase 3 | -0.00527846 |
| NFIB | nuclear factor I/B | -0.00525779 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00524394 |
| SFTPB | surfactant protein B | -0.00521096 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00520773 |
| PDZD2 | PDZ domain containing 2 | -0.00520609 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00520098 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.00519493 |
| DCLRE1C | DNA cross-link repair 1C | -0.00518775 |
| CD93 | CD93 molecule | -0.00518701 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00515022 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 | -0.00512605 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00511994 |
| CALCA | calcitonin-related polypeptide alpha | -0.00511338 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0051067 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.0051039 |
| TMEM8A | transmembrane protein 8A | -0.00509651 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.00509297 |
| SFTPC | surfactant protein C | -0.00509025 |
| CERT1 | ceramide transporter 1 | -0.0050901 |
| HMBOX1 | homeobox containing 1 | -0.00507384 |
| NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | -0.00506848 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00506078 |
| SARAF | store-operated calcium entry-associated regulatory factor | -0.00505469 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00504241 |
| FRY | furry homolog (Drosophila) | -0.00503859 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00503569 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0050297 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 | -0.0050265 |
| C3AR1 | complement component 3a receptor 1 | -0.00501982 |
| SEPTIN10 | septin 10 | -0.00501311 |
| UBE4A | ubiquitination factor E4A | -0.00500937 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00500935 |
| AQP9 | aquaporin 9 | -0.00499627 |
| PGD | phosphogluconate dehydrogenase | -0.00499464 |
| PDE4A | phosphodiesterase 4A, cAMP-specific | -0.00499408 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.00498551 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.00497464 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) | -0.004974 |
