| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | insulin|After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 3630) |
| External Link | https://ncbi.nlm.nih.gov/gene/3630 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the INS gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0151933 |
| LCN2 | lipocalin 2 | 0.0140308 |
| RNF167 | ring finger protein 167 | 0.0140277 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0139393 |
| TGM2 | transglutaminase 2 | 0.0133562 |
| S100P | S100 calcium binding protein P | 0.0130078 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0128499 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0118185 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0111052 |
| FN1 | fibronectin 1 | 0.0107404 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0105224 |
| MSMB | microseminoprotein, beta- | 0.0101825 |
| KYNU | kynureninase | 0.00977704 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00967451 |
| LAMC2 | laminin, gamma 2 | 0.00964175 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00949315 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00931547 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00928755 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00905393 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00898981 |
| GSDME | gasdermin E | 0.00898403 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.00898234 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00897559 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00896459 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00877098 |
| PALLD | palladin, cytoskeletal associated protein | 0.00872259 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00860725 |
| RRBP1 | ribosome binding protein 1 | 0.00859422 |
| S100A8 | S100 calcium binding protein A8 | 0.00854764 |
| CUX1 | cut-like homeobox 1 | 0.00852503 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00848241 |
| INHBA | inhibin, beta A | 0.00847334 |
| KLK11 | kallikrein-related peptidase 11 | 0.00838941 |
| PLXNB2 | plexin B2 | 0.00836855 |
| NKX3-1 | NK3 homeobox 1 | 0.00833719 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.008333 |
| INAVA | innate immunity activator | 0.00829417 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00809027 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.00807852 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00807726 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00806306 |
| CCND1 | cyclin D1 | 0.00801755 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00800348 |
| MINK1 | misshapen-like kinase 1 | 0.00798104 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00789971 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00789701 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00787048 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00786897 |
| TRIM29 | tripartite motif containing 29 | 0.00777193 |
| IL1RN | interleukin 1 receptor antagonist | 0.0077607 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00771972 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00770427 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00769321 |
| S100A2 | S100 calcium binding protein A2 | 0.00762779 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00762575 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0076165 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.007575 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | 0.00756251 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00755199 |
| S100A11 | S100 calcium binding protein A11 | 0.00752825 |
| LAMP1 | lysosomal-associated membrane protein 1 | 0.00743185 |
| CD9 | CD9 molecule | 0.00728387 |
| RETREG2 | reticulophagy regulator family member 2 | 0.00727892 |
| TSPAN8 | tetraspanin 8 | 0.00725211 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00724657 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00722909 |
| LAMB3 | laminin, beta 3 | 0.00715911 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00714197 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00710559 |
| KRT6A | keratin 6A, type II | 0.00708783 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00705732 |
| G0S2 | G0/G1 switch 2 | 0.00704621 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00698836 |
| STK38 | serine/threonine kinase 38 | 0.00694964 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00693265 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00691019 |
| FBN2 | fibrillin 2 | 0.00689081 |
| ERCC5 | excision repair cross-complementation group 5 | 0.00688535 |
| KLK2 | kallikrein-related peptidase 2 | 0.00686014 |
| SPATA20 | spermatogenesis associated 20 | 0.00685584 |
| KLK3 | kallikrein-related peptidase 3 | 0.00684994 |
| IRS2 | insulin receptor substrate 2 | 0.00684933 |
| FAM50A | family with sequence similarity 50, member A | 0.00683185 |
| OLFM4 | olfactomedin 4 | 0.00683182 |
| CYTH1 | cytohesin 1 | 0.00682357 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00681934 |
| TLE4 | transducin-like enhancer of split 4 | 0.00679848 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0067282 |
| SPRR3 | small proline-rich protein 3 | 0.0067136 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.00670169 |
| CTPS1 | CTP synthase 1 | 0.00669639 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00669446 |
| SFN | stratifin | 0.00667764 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00666874 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00665208 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 0.00664138 |
| KRT7 | keratin 7, type II | 0.00660668 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0065832 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.00656985 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00656537 |
| HSPB8 | heat shock 22kDa protein 8 | 0.0065589 |
| MVP | major vault protein | 0.00653245 |
| TRIM16 | tripartite motif containing 16 | 0.00646538 |
| KRT18 | keratin 18, type I | 0.00645871 |
| DUSP4 | dual specificity phosphatase 4 | 0.00643827 |
| COCH | cochlin | 0.00643679 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00643408 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00642447 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0064242 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00642221 |
| IRF9 | interferon regulatory factor 9 | 0.00641159 |
| RHCG | Rh family, C glycoprotein | 0.00640992 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00637154 |
| PAEP | progestagen-associated endometrial protein | 0.00633247 |
| GRN | granulin | 0.0062954 |
| SMAD7 | SMAD family member 7 | 0.00625721 |
| UPK1B | uroplakin 1B | 0.00625459 |
| GPX2 | glutathione peroxidase 2 | 0.00624297 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00623935 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00622621 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.00622593 |
| ABHD2 | abhydrolase domain containing 2 | 0.00621952 |
| C5AR1 | complement component 5a receptor 1 | 0.00621888 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00620703 |
| GPX3 | glutathione peroxidase 3 | 0.00617328 |
| BGN | biglycan | 0.00616362 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00614353 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00613333 |
| MAGED1 | melanoma antigen family D1 | 0.00612889 |
| LIPG | lipase, endothelial | 0.00612543 |
| HDLBP | high density lipoprotein binding protein | 0.00611443 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00610744 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00610092 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00609837 |
| MATN2 | matrilin 2 | 0.00608501 |
| DST | dystonin | 0.0060776 |
| PRKCA | protein kinase C, alpha | 0.0060674 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00606456 |
| MTMR11 | myotubularin related protein 11 | 0.00606319 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 | 0.00605708 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00603952 |
| WDR45 | WD repeat domain 45 | 0.00603783 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00602875 |
| PLXNA1 | plexin A1 | 0.00602852 |
| CRTC3 | CREB regulated transcription coactivator 3 | 0.00602563 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00602041 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00600681 |
| RIN2 | Ras and Rab interactor 2 | 0.00600314 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00599999 |
| USP47 | ubiquitin specific peptidase 47 | 0.00599982 |
| STK26 | serine/threonine protein kinase 26 | 0.00598266 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00598145 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00596584 |
| PTHLH | parathyroid hormone-like hormone | 0.00596314 |
| TUFT1 | tuftelin 1 | 0.00594983 |
| NDNF | neuron-derived neurotrophic factor | 0.00594607 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00592344 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00592275 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00584384 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.00583445 |
| YBX3 | Y box binding protein 3 | 0.0058135 |
| CSTA | cystatin A (stefin A) | 0.00577524 |
| SGPL1 | sphingosine-1-phosphate lyase 1 | 0.00577236 |
| ABHD4 | abhydrolase domain containing 4 | 0.00577229 |
| ENGASE | endo-beta-N-acetylglucosaminidase | 0.00577038 |
| CRNN | cornulin | 0.00576792 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00576634 |
| MSLN | mesothelin | 0.00576326 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.00576259 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.00576029 |
| SIK1 | salt-inducible kinase 1 | 0.00573188 |
| TAPBP | TAP binding protein (tapasin) | 0.00572916 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00572513 |
| TCTA | T-cell leukemia translocation altered | 0.00571639 |
| WDR6 | WD repeat domain 6 | 0.00570468 |
| CSK | c-src tyrosine kinase | 0.00570387 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.00565904 |
| MEIS1 | Meis homeobox 1 | 0.0056509 |
| FTSJ3 | FtsJ homolog 3 (E. coli) | 0.00562395 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.0056219 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00559177 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00556802 |
| FZD2 | frizzled class receptor 2 | 0.00556073 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00554814 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.00554491 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00554444 |
| EFHD2 | EF-hand domain family, member D2 | 0.00554306 |
| BICC1 | BicC family RNA binding protein 1 | 0.00554004 |
| WWC3 | WWC family member 3 | 0.00552944 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.00551682 |
| AGR2 | anterior gradient 2 | 0.00550276 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00549589 |
| TBX3 | T-box 3 | 0.00549433 |
| IL7R | interleukin 7 receptor | 0.00548584 |
| PDGFC | platelet derived growth factor C | 0.00548496 |
| WDR13 | WD repeat domain 13 | 0.00548416 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00547858 |
| RRAGD | Ras-related GTP binding D | 0.00546497 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00545839 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00545719 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.00545574 |
| MMP7 | matrix metallopeptidase 7 | 0.00544399 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 0.00544338 |
| SRRT | serrate, RNA effector molecule | 0.00544066 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00542723 |
| NEK9 | NIMA-related kinase 9 | 0.00542664 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00542425 |
| RBM10 | RNA binding motif protein 10 | 0.00541932 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.005416 |
| RBM6 | RNA binding motif protein 6 | 0.00540353 |
| NOTCH2 | notch 2 | 0.00539756 |
| JAG1 | jagged 1 | 0.00538642 |
| TJP2 | tight junction protein 2 | 0.00538292 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00537665 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 | 0.00536754 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00536685 |
| TGFA | transforming growth factor, alpha | 0.00536229 |
| PLBD1 | phospholipase B domain containing 1 | 0.00535811 |
| YLPM1 | YLP motif containing 1 | 0.00535307 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00533333 |
| BRD4 | bromodomain containing 4 | 0.0053274 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | 0.00532429 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00532407 |
| KRT13 | keratin 13, type I | 0.00531594 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.00530632 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0053063 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.00528365 |
| RBM34 | RNA binding motif protein 34 | 0.00527873 |
| TMEM176B | transmembrane protein 176B | 0.00526191 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0052498 |
| KLC1 | kinesin light chain 1 | 0.00523 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.00522199 |
| KAZN | kazrin, periplakin interacting protein | 0.00521535 |
| ZYX | zyxin | 0.00520733 |
| WBP2 | WW domain binding protein 2 | 0.00520569 |
| PER1 | period circadian clock 1 | 0.00519602 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00519587 |
| KRT17 | keratin 17, type I | 0.00519331 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.00519126 |
| SLC16A4 | solute carrier family 16, member 4 | 0.00518919 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | 0.00518767 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00517889 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00516915 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00516825 |
| JUP | junction plakoglobin | 0.0051625 |
| MKRN1 | makorin ring finger protein 1 | 0.0051545 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.00514418 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00514131 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.00513097 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | 0.00512437 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0153219 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0149761 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0136626 |
| MT1E | metallothionein 1E | -0.0125077 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0116652 |
| CA2 | carbonic anhydrase II | -0.0114945 |
| CNN3 | calponin 3, acidic | -0.011437 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0112687 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0111583 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0107651 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.0105226 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.0104472 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0103973 |
| LUM | lumican | -0.0103933 |
| FCGBP | Fc fragment of IgG binding protein | -0.0101763 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0101484 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.0100234 |
| MT1F | metallothionein 1F | -0.00967468 |
| XIC | X chromosome inactivation center | -0.00951394 |
| LOX | lysyl oxidase | -0.00951166 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00920645 |
| ESR1 | estrogen receptor 1 | -0.00918503 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00897096 |
| CLDND1 | claudin domain containing 1 | -0.00897014 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00891295 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00872265 |
| HHEX | hematopoietically expressed homeobox | -0.0087101 |
| PLP1 | proteolipid protein 1 | -0.00861431 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00858538 |
| COX7B | cytochrome c oxidase subunit VIIb | -0.00844809 |
| RTN2 | reticulon 2 | -0.00827489 |
| MRPL39 | mitochondrial ribosomal protein L39 | -0.00823549 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00823363 |
| COMMD10 | COMM domain containing 10 | -0.00821824 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00811376 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | -0.00811203 |
| ATG5 | autophagy related 5 | -0.00807724 |
| CPE | carboxypeptidase E | -0.00806432 |
| COL3A1 | collagen, type III, alpha 1 | -0.00804404 |
| HSPB1 | heat shock 27kDa protein 1 | -0.008006 |
| COMMD8 | COMM domain containing 8 | -0.00799863 |
| DCN | decorin | -0.00795473 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00793073 |
| MT1G | metallothionein 1G | -0.00791669 |
| ZG16 | zymogen granule protein 16 | -0.00788126 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | -0.0078765 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00787226 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | -0.0077853 |
| FZD6 | frizzled class receptor 6 | -0.00776722 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | -0.00776078 |
| STMN2 | stathmin 2 | -0.00775067 |
| WBP5 | WW domain binding protein 5 | -0.00772251 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00771302 |
| AK4 | adenylate kinase 4 | -0.00767232 |
| LYPLA1 | lysophospholipase I | -0.00765606 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | -0.00763327 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00760562 |
| FASTKD3 | FAST kinase domains 3 | -0.00760202 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00754721 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00753384 |
| RCAN1 | regulator of calcineurin 1 | -0.0075167 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00748577 |
| BTG3 | BTG family, member 3 | -0.00747054 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00745364 |
| OIP5 | Opa interacting protein 5 | -0.00744207 |
| ZNF395 | zinc finger protein 395 | -0.00733604 |
| WDR7 | WD repeat domain 7 | -0.00731682 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00729832 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.00726927 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00723624 |
| TMEM70 | transmembrane protein 70 | -0.0072357 |
| MRPL13 | mitochondrial ribosomal protein L13 | -0.00721268 |
| CCNC | cyclin C | -0.00718635 |
| MAT2B | methionine adenosyltransferase II, beta | -0.00718018 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00713939 |
| TPD52 | tumor protein D52 | -0.00704407 |
| MRPS28 | mitochondrial ribosomal protein S28 | -0.00702345 |
| CLCA4 | chloride channel accessory 4 | -0.00701909 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0070112 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00699963 |
| CALB2 | calbindin 2 | -0.00699864 |
| RPA3 | replication protein A3, 14kDa | -0.00697586 |
| CA4 | carbonic anhydrase IV | -0.00697347 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | -0.0069563 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00695201 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00691948 |
| MEN1 | multiple endocrine neoplasia I | -0.00690278 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00688657 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00688144 |
| FAM3C | family with sequence similarity 3, member C | -0.00687004 |
| HINT1 | histidine triad nucleotide binding protein 1 | -0.00686976 |
| CYB5R4 | cytochrome b5 reductase 4 | -0.00685392 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00681912 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00681273 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.00680877 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | -0.00680553 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | -0.00677853 |
| PLK1 | polo-like kinase 1 | -0.00675317 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00673118 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00672587 |
| CTSG | cathepsin G | -0.00672301 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00671713 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00670454 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00669237 |
| ASPN | asporin | -0.00669206 |
| MFAP5 | microfibrillar associated protein 5 | -0.0066646 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00662408 |
| PLIN1 | perilipin 1 | -0.00660576 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00659273 |
| TMEM126B | transmembrane protein 126B | -0.00658554 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | -0.0065592 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00652362 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0065074 |
| DUT | deoxyuridine triphosphatase | -0.00650285 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.0065005 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.00649399 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00649215 |
| SNX7 | sorting nexin 7 | -0.00648883 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00647531 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00647175 |
| TYRP1 | tyrosinase-related protein 1 | -0.00646859 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0064651 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00645175 |
| GCG | glucagon | -0.00644862 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00640043 |
| RBBP4 | retinoblastoma binding protein 4 | -0.0063824 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.00637972 |
| CD200 | CD200 molecule | -0.0063783 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.0063725 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00633902 |
| CYTL1 | cytokine-like 1 | -0.00631659 |
| LY96 | lymphocyte antigen 96 | -0.00631442 |
| MOCS2 | molybdenum cofactor synthesis 2 | -0.00629426 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00628371 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00627845 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0062681 |
| HSPA13 | heat shock protein 70kDa family, member 13 | -0.00625429 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -0.00624407 |
| AQP8 | aquaporin 8 | -0.00623051 |
| TMEM50B | transmembrane protein 50B | -0.00623003 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | -0.00622479 |
| RGCC | regulator of cell cycle | -0.00621815 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00619724 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 | -0.00619532 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00616099 |
| SELENOW | selenoprotein W | -0.00615165 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00615057 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00614679 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0061155 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | -0.00611336 |
| PLS3 | plastin 3 | -0.00610678 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00609915 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00606295 |
| RBBP8 | retinoblastoma binding protein 8 | -0.00605654 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00605183 |
| CD164 | CD164 molecule, sialomucin | -0.00604775 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00604494 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | -0.00599314 |
| MT1H | metallothionein 1H | -0.00598433 |
| TXNL1 | thioredoxin-like 1 | -0.00597369 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | -0.00596006 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00595759 |
| MEX3D | mex-3 RNA binding family member D | -0.00595353 |
| MED28 | mediator complex subunit 28 | -0.00595278 |
| LRRC40 | leucine rich repeat containing 40 | -0.00591981 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00590902 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00590147 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00589792 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.00587182 |
| ACTB | actin, beta | -0.00587057 |
| FBN1 | fibrillin 1 | -0.00586859 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00586822 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00586746 |
| CLCA1 | chloride channel accessory 1 | -0.00584912 |
| NUP37 | nucleoporin 37kDa | -0.00583498 |
| YIPF5 | Yip1 domain family, member 5 | -0.0058262 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00582347 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.0058183 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00581328 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.0057916 |
| TIPRL | TOR signaling pathway regulator | -0.00578684 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00578211 |
| GFAP | glial fibrillary acidic protein | -0.00574223 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.00573453 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.00572706 |
| CFH | complement factor H | -0.00572582 |
| GRAMD2B | GRAM domain containing 2B | -0.00572351 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00569513 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00569321 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.005676 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00566726 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00566545 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | -0.00565333 |
| ZNHIT3 | zinc finger, HIT-type containing 3 | -0.00563816 |
| PDCD10 | programmed cell death 10 | -0.00563391 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00562877 |
| PEG3 | paternally expressed 3 | -0.00562155 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | -0.00561963 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.00561168 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00560985 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | -0.0056056 |
| TMEM14B | transmembrane protein 14B | -0.00560524 |
| SELENOF | selenoprotein F | -0.00560496 |
| GUCA2B | guanylate cyclase activator 2B (uroguanylin) | -0.00560297 |
| MTERF3 | mitochondrial transcription termination factor 3 | -0.00560252 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00560179 |
| RELN | reelin | -0.00556392 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | -0.00556156 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | -0.00555094 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00554955 |
| JAM2 | junctional adhesion molecule 2 | -0.00554065 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -0.00554012 |
| CLDN8 | claudin 8 | -0.00552831 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) | -0.00550894 |
| CETN3 | centrin, EF-hand protein, 3 | -0.00550539 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | -0.0054883 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | -0.00548806 |
| SMAD5 | SMAD family member 5 | -0.00548544 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00548433 |
| RAB4A | RAB4A, member RAS oncogene family | -0.00544779 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.0054468 |
| FABP7 | fatty acid binding protein 7, brain | -0.00544159 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00543184 |
| LRRC15 | leucine rich repeat containing 15 | -0.00543095 |
| RANBP1 | RAN binding protein 1 | -0.00542832 |
| PRELID3B | PRELI domain containing 3B | -0.00542256 |
| FRZB | frizzled-related protein | -0.00541907 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.00541839 |
| CRIP2 | cysteine-rich protein 2 | -0.00539499 |
| UNG | uracil-DNA glycosylase | -0.00538849 |
| BSG | basigin (Ok blood group) | -0.00538621 |
| FAM162A | family with sequence similarity 162, member A | -0.00538444 |
| KLK5 | kallikrein-related peptidase 5 | -0.0053717 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00537102 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00535881 |
| MRPL35 | mitochondrial ribosomal protein L35 | -0.00535871 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | -0.00535346 |
| MSX1 | msh homeobox 1 | -0.00534784 |
| UBE2N | ubiquitin-conjugating enzyme E2N | -0.00533826 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.00533514 |
| EDN3 | endothelin 3 | -0.00533131 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | -0.00532862 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.00532762 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00532015 |
| PDGFD | platelet derived growth factor D | -0.00531825 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00531592 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00531377 |
| PRDX3 | peroxiredoxin 3 | -0.005312 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0053098 |
| SUMO1 | small ubiquitin-like modifier 1 | -0.00530066 |
