INSR Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description insulin receptor|After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3643)
External Link http://www.ncbi.nlm.nih.gov/gene/3643
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Genes

20 substrates of the kinase INSR from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
ARHGAP5 Rho GTPase activating protein 5
BLVRA biliverdin reductase A
CAV1 caveolin 1, caveolae protein, 22kDa
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
FABP4 fatty acid binding protein 4, adipocyte
GAB1 GRB2-associated binding protein 1
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PHB prohibitin
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PTEN phosphatase and tensin homolog
PTPN6 protein tyrosine phosphatase, non-receptor type 6
SH2B2 SH2B adaptor protein 2
SOCS3 suppressor of cytokine signaling 3
STAT5B signal transducer and activator of transcription 5B
STXBP3 syntaxin binding protein 3