IPC-298 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

289 genes with high or low expression in IPC-298 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 3.54608
POLB polymerase (DNA directed), beta 3.20382
SDCBP syndecan binding protein (syntenin) 3.18162
FLOT1 flotillin 1 3.10987
MXI1 MAX interactor 1, dimerization protein 3.10419
CDC16 cell division cycle 16 2.91592
PHGDH phosphoglycerate dehydrogenase 2.89843
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 2.88821
PRMT2 protein arginine methyltransferase 2 2.64422
RCAN1 regulator of calcineurin 1 2.6208
HMG20B high mobility group 20B 2.56809
PMP2 peripheral myelin protein 2 2.51189
ADSL adenylosuccinate lyase 2.48496
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 2.48443
TRAF3IP2 TRAF3 interacting protein 2 2.46996
TDRD3 tudor domain containing 3 2.44046
TAC1 tachykinin, precursor 1 2.42501
SORT1 sortilin 1 2.42432
IL24 interleukin 24 2.40759
CIT citron rho-interacting serine/threonine kinase 2.36079
TRIM2 tripartite motif containing 2 2.28778
MYO5A myosin VA (heavy chain 12, myoxin) 2.27414
VAT1 vesicle amine transport 1 2.24656
NHEJ1 nonhomologous end-joining factor 1 2.23988
TULP4 tubby like protein 4 2.21248
CC2D1A coiled-coil and C2 domain containing 1A 2.18788
OCA2 oculocutaneous albinism II 2.18709
ANKRD28 ankyrin repeat domain 28 2.16395
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 2.16264
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.15123
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 2.1165
MTIF2 mitochondrial translational initiation factor 2 2.11254
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.11212
CD63 CD63 molecule 2.09979
LZTS1 leucine zipper, putative tumor suppressor 1 2.09877
TFB1M transcription factor B1, mitochondrial 2.04808
XYLB xylulokinase homolog (H. influenzae) 2.01989
SLC22A18 solute carrier family 22, member 18 2.01749
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 2.00859
TRIM33 tripartite motif containing 33 1.99442
GPM6B glycoprotein M6B 1.98195
CBR3 carbonyl reductase 3 1.9764
MOSPD2 motile sperm domain containing 2 1.96223
ETV5 ets variant 5 1.92675
RNMT RNA (guanine-7-) methyltransferase 1.91937
MMP17 matrix metallopeptidase 17 (membrane-inserted) 1.91739
LONP2 lon peptidase 2, peroxisomal 1.91271
RENBP renin binding protein 1.90758
FABP7 fatty acid binding protein 7, brain 1.90673
CSTB cystatin B (stefin B) 1.90145
TYRP1 tyrosinase-related protein 1 1.89943
DUSP10 dual specificity phosphatase 10 1.89407
SGK1 serum/glucocorticoid regulated kinase 1 1.89399
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 1.89265
GSTO1 glutathione S-transferase omega 1 1.8799
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 1.87366
DAAM2 dishevelled associated activator of morphogenesis 2 1.85594
LYST lysosomal trafficking regulator 1.84756
TRAK2 trafficking protein, kinesin binding 2 1.84201
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 1.83719
RHOQ ras homolog family member Q 1.81697
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 1.79539
EPRS glutamyl-prolyl-tRNA synthetase 1.79395
CSDE1 cold shock domain containing E1, RNA-binding 1.79303
CLCA3P chloride channel accessory 3, pseudogene 1.78167
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.77894
STX7 syntaxin 7 1.7758
WFDC1 WAP four-disulfide core domain 1 1.77335
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 1.7713
AFG3L2 AFG3-like AAA ATPase 2 1.76643
SLC16A6 solute carrier family 16, member 6 1.76544
APOLD1 apolipoprotein L domain containing 1 1.76034
DCT dopachrome tautomerase 1.75949
SDC3 syndecan 3 1.75281
GARS glycyl-tRNA synthetase 1.7526
PGPEP1 pyroglutamyl-peptidase I 1.73616
QDPR quinoid dihydropteridine reductase 1.72952
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 1.70748
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.70742
INPP5F inositol polyphosphate-5-phosphatase F 1.70137
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 1.69252
GDI2 GDP dissociation inhibitor 2 1.68118
GP5 glycoprotein V (platelet) 1.67627
TBC1D16 TBC1 domain family, member 16 1.66328
GJB1 gap junction protein, beta 1, 32kDa 1.64551
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 1.6449
PSRC1 proline/serine-rich coiled-coil 1 1.64257
HELZ helicase with zinc finger 1.63804
RASIP1 Ras interacting protein 1 1.63285
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.6317
SEC14L4 SEC14-like 4 (S. cerevisiae) 1.62961
RXFP3 relaxin/insulin-like family peptide receptor 3 1.62751
DYNLT3 dynein, light chain, Tctex-type 3 1.6267
FBXO7 F-box protein 7 1.62412
ATP10A ATPase, class V, type 10A 1.62215
OR11A1 olfactory receptor, family 11, subfamily A, member 1 1.62048
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 1.62006
CELA2A chymotrypsin-like elastase family, member 2A 1.61523
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 1.6106
SOX10 SRY (sex determining region Y)-box 10 1.60501
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 1.6035
PLXNC1 plexin C1 1.60126
DCLRE1C DNA cross-link repair 1C 1.59555
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 1.59313
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 1.59185
TSPAN14 tetraspanin 14 1.588
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.58425
MITF microphthalmia-associated transcription factor 1.58108
ACSL3 acyl-CoA synthetase long-chain family member 3 1.5786
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.57764
SNX9 sorting nexin 9 1.57764
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 1.57522
CAPN3 calpain 3, (p94) 1.57276
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense 1.56707
CDH19 cadherin 19, type 2 1.55435
SNX10 sorting nexin 10 1.55417
TIMP3 TIMP metallopeptidase inhibitor 3 1.55244
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 1.55242
PBRM1 polybromo 1 1.54623
HSF4 heat shock transcription factor 4 1.53363
FIG4 FIG4 phosphoinositide 5-phosphatase 1.52741
AP3M2 adaptor-related protein complex 3, mu 2 subunit 1.52285
GPR137B G protein-coupled receptor 137B 1.5214
PWP1 PWP1 homolog (S. cerevisiae) 1.51898
PYGB phosphorylase, glycogen; brain 1.51846
STX10 syntaxin 10 1.51458
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 1.51281
ZFYVE16 zinc finger, FYVE domain containing 16 1.50956
SCCPDH saccharopine dehydrogenase (putative) 1.50907
COPE coatomer protein complex, subunit epsilon 1.50419
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 1.49793
CPN1 carboxypeptidase N, polypeptide 1 1.49501
SARS seryl-tRNA synthetase 1.4917
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.49084
XKR8 XK, Kell blood group complex subunit-related family, member 8 1.49031
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.49015
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 1.48783
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 1.48424
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.48233
MTDH metadherin 1.48142
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 1.4759
NEK1 NIMA-related kinase 1 1.47408
SASH1 SAM and SH3 domain containing 1 1.47189
APOD apolipoprotein D 1.47074
PKNOX2 PBX/knotted 1 homeobox 2 1.46663
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 1.45664
RGS12 regulator of G-protein signaling 12 1.45485
KRT3 keratin 3, type II 1.45447
BNC2 basonuclin 2 1.45297
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 1.45136
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 1.44994
DNASE2 deoxyribonuclease II, lysosomal 1.44928
DSTYK dual serine/threonine and tyrosine protein kinase 1.44414
STXBP1 syntaxin binding protein 1 1.44353
TBR1 T-box, brain, 1 1.43765
EMX2 empty spiracles homeobox 2 1.43606
CFHR5 complement factor H-related 5 1.43488
RPL23AP7 ribosomal protein L23a pseudogene 7 1.43252
WDR3 WD repeat domain 3 1.43203
RAD23A RAD23 homolog A (S. cerevisiae) 1.4296
MMP20 matrix metallopeptidase 20 1.4263
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.42238
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.41804

low expression

Symbol Name Standardized Value
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -3.53725
WDR76 WD repeat domain 76 -3.53453
GSDMB gasdermin B -3.45289
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -2.88133
CELF1 CUGBP, Elav-like family member 1 -2.80255
DCP2 decapping mRNA 2 -2.59111
EPHB2 EPH receptor B2 -2.46617
BCL2L11 BCL2-like 11 (apoptosis facilitator) -2.42442
PLXNA2 plexin A2 -2.27625
TDG thymine-DNA glycosylase -2.26539
SLC17A4 solute carrier family 17, member 4 -2.26407
KLF10 Kruppel-like factor 10 -2.26198
TUBD1 tubulin, delta 1 -2.21797
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) -2.20784
TFEB transcription factor EB -2.18921
PPP1R12B protein phosphatase 1, regulatory subunit 12B -2.18657
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 -2.16643
GEMIN4 gem (nuclear organelle) associated protein 4 -2.16201
RCE1 Ras converting CAAX endopeptidase 1 -2.13149
ZNF273 zinc finger protein 273 -2.10717
SOX15 SRY (sex determining region Y)-box 15 -2.07817
HCRP1 hepatocellular carcinoma-related HCRP1 -2.07274
MED4 mediator complex subunit 4 -2.06749
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -2.06519
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.06456
TCERG1 transcription elongation regulator 1 -2.04954
NUP37 nucleoporin 37kDa -2.03539
PAPD7 PAP associated domain containing 7 -2.00454
SF3B4 splicing factor 3b, subunit 4, 49kDa -2.00389
CCDC132 coiled-coil domain containing 132 -1.96229
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -1.95573
CAPN15 calpain 15 -1.9522
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) -1.94754
MOCS3 molybdenum cofactor synthesis 3 -1.93933
HIST1H2AE histone cluster 1, H2ae -1.93862
ZC3H11A zinc finger CCCH-type containing 11A -1.93413
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) -1.9279
HIST1H2BF histone cluster 1, H2bf -1.90955
KPNA5 karyopherin alpha 5 (importin alpha 6) -1.90343
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -1.90017
REL v-rel avian reticuloendotheliosis viral oncogene homolog -1.89776
MIS12 MIS12 kinetochore complex component -1.86296
CLCF1 cardiotrophin-like cytokine factor 1 -1.85835
CREBZF CREB/ATF bZIP transcription factor -1.84936
UBOX5 U-box domain containing 5 -1.84819
MAML1 mastermind-like 1 (Drosophila) -1.84458
RAD1 RAD1 checkpoint DNA exonuclease -1.82174
RANBP6 RAN binding protein 6 -1.82164
SMG6 SMG6 nonsense mediated mRNA decay factor -1.81596
HIST2H2BE histone cluster 2, H2be -1.79563
MAN1A1 mannosidase, alpha, class 1A, member 1 -1.78836
ELAC2 elaC ribonuclease Z 2 -1.74255
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -1.74063
ZNF200 zinc finger protein 200 -1.73802
MCPH1 microcephalin 1 -1.73778
ARHGAP25 Rho GTPase activating protein 25 -1.72335
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis) -1.72141
SCN10A sodium channel, voltage gated, type X alpha subunit -1.71081
PRKCI protein kinase C, iota -1.70676
SPPL2B signal peptide peptidase like 2B -1.70212
GLRA1 glycine receptor, alpha 1 -1.69872
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 -1.69845
CLP1 cleavage and polyadenylation factor I subunit 1 -1.69315
RS1 retinoschisin 1 -1.69132
IL11RA interleukin 11 receptor, alpha -1.69112
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 -1.6884
PPIF peptidylprolyl isomerase F -1.6665
BMP6 bone morphogenetic protein 6 -1.66622
TUBGCP4 tubulin, gamma complex associated protein 4 -1.66204
PISD phosphatidylserine decarboxylase -1.65888
ZNF197 zinc finger protein 197 -1.65383
DRG2 developmentally regulated GTP binding protein 2 -1.65291
ANKEF1 ankyrin repeat and EF-hand domain containing 1 -1.65001
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -1.64776
MEGF8 multiple EGF-like-domains 8 -1.63781
MXRA8 matrix-remodelling associated 8 -1.63649
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -1.62548
KLHL2 kelch-like family member 2 -1.62441
NFYB nuclear transcription factor Y, beta -1.61845
AGTR2 angiotensin II receptor, type 2 -1.61729
CDK9 cyclin-dependent kinase 9 -1.60722
CDK10 cyclin-dependent kinase 10 -1.60524
ADAM19 ADAM metallopeptidase domain 19 -1.60386
STX5 syntaxin 5 -1.60281
MED6 mediator complex subunit 6 -1.60262
GIPC2 GIPC PDZ domain containing family, member 2 -1.5977
CCBL1 cysteine conjugate-beta lyase, cytoplasmic -1.59481
KRT8P12 keratin 8 pseudogene 12 -1.58732
CLEC4M C-type lectin domain family 4, member M -1.57438
CDC42SE2 CDC42 small effector 2 -1.57129
BRWD1 bromodomain and WD repeat domain containing 1 -1.56604
SEC62 SEC62 homolog (S. cerevisiae) -1.56099
CNR1 cannabinoid receptor 1 (brain) -1.56029
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -1.55744
RAP1GAP RAP1 GTPase activating protein -1.5471
ZNF35 zinc finger protein 35 -1.54045
HRASLS HRAS-like suppressor -1.53374
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 -1.53072
MFAP1 microfibrillar-associated protein 1 -1.53014
CISH cytokine inducible SH2-containing protein -1.52405
CNOT6 CCR4-NOT transcription complex, subunit 6 -1.5192
KIAA0753 KIAA0753 -1.51903
MRPL33 mitochondrial ribosomal protein L33 -1.51582
MYBPC3 myosin binding protein C, cardiac -1.51225
SFXN1 sideroflexin 1 -1.51062
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -1.5001
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 -1.49723
EML1 echinoderm microtubule associated protein like 1 -1.4885
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -1.48799
ALG12 ALG12, alpha-1,6-mannosyltransferase -1.4842
WNT6 wingless-type MMTV integration site family, member 6 -1.48164
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 -1.47416
ZBTB25 zinc finger and BTB domain containing 25 -1.47037
GRIA3 glutamate receptor, ionotropic, AMPA 3 -1.46816
ZNF629 zinc finger protein 629 -1.45731
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -1.44954
PANK3 pantothenate kinase 3 -1.44103
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) -1.436
WWC1 WW and C2 domain containing 1 -1.43506
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -1.435
FCGRT Fc fragment of IgG, receptor, transporter, alpha -1.43294
GRB7 growth factor receptor-bound protein 7 -1.43116
DDB2 damage-specific DNA binding protein 2, 48kDa -1.43099
MED7 mediator complex subunit 7 -1.42808
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 -1.42382
LRRC15 leucine rich repeat containing 15 -1.41996