| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | IQ 1 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the IQ 1_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.138199 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.104164 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0930634 |
| VCL | vinculin | 0.0840338 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.080425 |
| TLE4 | transducin-like enhancer of split 4 | 0.0778196 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0643192 |
| RNF213 | ring finger protein 213 | 0.0566958 |
| SIK2 | salt-inducible kinase 2 | 0.0565367 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0525421 |
| BPTF | bromodomain PHD finger transcription factor | 0.05026 |
| PDE10A | phosphodiesterase 10A | 0.049575 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.047203 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0463671 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0458222 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0456242 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.04535 |
| STK38L | serine/threonine kinase 38 like | 0.0448289 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0447425 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.044214 |
| INTS6 | integrator complex subunit 6 | 0.0434993 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0433688 |
| GLCCI1 | glucocorticoid induced 1 | 0.0417483 |
| EGR1 | early growth response 1 | 0.0408845 |
| TRIB2 | tribbles pseudokinase 2 | 0.0401058 |
| RPL7A | ribosomal protein L7a | 0.0398608 |
| LPIN1 | lipin 1 | 0.0390701 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0387389 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0384743 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0378247 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0378064 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0374297 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0368044 |
| PLPP1 | phospholipid phosphatase 1 | 0.0357304 |
| VEGFA | vascular endothelial growth factor A | 0.035598 |
| PLAT | plasminogen activator, tissue | 0.0350404 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0336326 |
| FHL2 | four and a half LIM domains 2 | 0.0325949 |
| B2M | beta-2-microglobulin | 0.0323889 |
| RPS17 | ribosomal protein S17 | 0.0323572 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.032306 |
| FAM107B | family with sequence similarity 107, member B | 0.0318737 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0311718 |
| AMOTL1 | angiomotin like 1 | 0.0307346 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0306355 |
| FERMT2 | fermitin family member 2 | 0.0305299 |
| FN1 | fibronectin 1 | 0.0303572 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0303269 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0301409 |
| GAB2 | GRB2-associated binding protein 2 | 0.0301229 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0287966 |
| MCL1 | myeloid cell leukemia 1 | 0.0285559 |
| CALR | calreticulin | 0.02752 |
| TBX2 | T-box 2 | 0.0272876 |
| TPM1 | tropomyosin 1 (alpha) | 0.027004 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0266192 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0265473 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0263895 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0260714 |
| FMN1 | formin 1 | 0.0258123 |
| DLG5 | discs, large homolog 5 (Drosophila) | 0.0257371 |
| CDK6 | cyclin-dependent kinase 6 | 0.0254161 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0253661 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.025363 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0252181 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0250462 |
| BRD2 | bromodomain containing 2 | 0.0248844 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0248473 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0246169 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0245459 |
| THBS1 | thrombospondin 1 | 0.0245416 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0245269 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0240635 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.023922 |
| RPL4 | ribosomal protein L4 | 0.0238416 |
| PNN | pinin, desmosome associated protein | 0.0236311 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0233705 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0231913 |
| KLHL13 | kelch-like family member 13 | 0.0231784 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0229215 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0228968 |
| PCDH17 | protocadherin 17 | 0.0226322 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0224823 |
| MYO1E | myosin IE | 0.0222866 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0221775 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.0221166 |
| RPL3 | ribosomal protein L3 | 0.0218354 |
| SMAD3 | SMAD family member 3 | 0.0212391 |
| SEPTIN9 | septin 9 | 0.0210223 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.020884 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.020536 |
| RPL19 | ribosomal protein L19 | 0.0204127 |
| PCBP2 | poly(rC) binding protein 2 | 0.0203758 |
| PCNX4 | pecanex 4 | 0.0201873 |
| JUP | junction plakoglobin | 0.0201795 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.020006 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0199952 |
| MMP2 | matrix metallopeptidase 2 | 0.0199483 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0199457 |
| VGF | VGF nerve growth factor inducible | 0.0197427 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.172101 |
| IGF2 | insulin-like growth factor 2 | -0.143262 |
| VIM | vimentin | -0.117721 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.103511 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0911695 |
| PTMA | prothymosin, alpha | -0.0809424 |
| HELZ | helicase with zinc finger | -0.0755663 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0656468 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0599355 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0594688 |
| FNBP1 | formin binding protein 1 | -0.056668 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0560576 |
| COL3A1 | collagen, type III, alpha 1 | -0.0549346 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0542372 |
| LSAMP | limbic system-associated membrane protein | -0.0529388 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.051372 |
| RPL34 | ribosomal protein L34 | -0.0510592 |
| HMGB2 | high mobility group box 2 | -0.0509763 |
| WDR45B | WD repeat domain 45B | -0.0509257 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0498842 |
| MSI2 | musashi RNA-binding protein 2 | -0.0487028 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0476466 |
| OGA | O-GlcNAcase | -0.0475919 |
| FAM13A | family with sequence similarity 13, member A | -0.0475172 |
| RPLP1 | ribosomal protein, large, P1 | -0.0474449 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0462725 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0459261 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0457437 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0448304 |
| SPAG9 | sperm associated antigen 9 | -0.0438518 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0435909 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0434241 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0433442 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0427904 |
| HIP1 | huntingtin interacting protein 1 | -0.0425593 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0424912 |
| COL1A1 | collagen, type I, alpha 1 | -0.0420848 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0412335 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0409159 |
| CANX | calnexin | -0.0407335 |
| S100A6 | S100 calcium binding protein A6 | -0.0406072 |
| NDRG1 | N-myc downstream regulated 1 | -0.0399197 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0398418 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0388571 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0385339 |
| SBF2 | SET binding factor 2 | -0.0385218 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0384168 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0376863 |
| PTK2 | protein tyrosine kinase 2 | -0.0376832 |
| CCND1 | cyclin D1 | -0.0372595 |
| CDC27 | cell division cycle 27 | -0.037214 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0371734 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0371628 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0368056 |
| SSH2 | slingshot protein phosphatase 2 | -0.0365961 |
| MEF2A | myocyte enhancer factor 2A | -0.0365958 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0365209 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0362381 |
| LMNA | lamin A/C | -0.036156 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0356438 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0354509 |
| RIOK3 | RIO kinase 3 | -0.0354139 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0346192 |
| H1-0 | H1.0 linker histone | -0.0345234 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0340951 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.034091 |
| QKI | QKI, KH domain containing, RNA binding | -0.0337465 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0337405 |
| FOXK2 | forkhead box K2 | -0.0335855 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0334035 |
| TCF12 | transcription factor 12 | -0.0332428 |
| NPR2 | natriuretic peptide receptor 2 | -0.0331779 |
| GOLGA4 | golgin A4 | -0.0329596 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0327418 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0326909 |
| MYO6 | myosin VI | -0.0321307 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0320111 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0317568 |
| TMSB10 | thymosin beta 10 | -0.0314224 |
| USP3 | ubiquitin specific peptidase 3 | -0.0314012 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0308467 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0306337 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.030289 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0299809 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0298589 |
| RTN4 | reticulon 4 | -0.029822 |
| AHR | aryl hydrocarbon receptor | -0.0295235 |
| TET2 | tet methylcytosine dioxygenase 2 | -0.0294285 |
| MAP4 | microtubule-associated protein 4 | -0.0291148 |
| CEP350 | centrosomal protein 350kDa | -0.0288724 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0287669 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0287604 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0284838 |
| PKM | pyruvate kinase, muscle | -0.0284578 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0283899 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0281879 |
| NUP153 | nucleoporin 153kDa | -0.0281435 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0280421 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0280012 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0279473 |
