| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | IQ 1 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the IQ 1_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.124752 |
| FAT1 | FAT atypical cadherin 1 | 0.0852136 |
| ONECUT3 | one cut homeobox 3 | 0.0850258 |
| TNS4 | tensin 4 | 0.0737304 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0625896 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0591609 |
| ASPH | aspartate beta-hydroxylase | 0.0550439 |
| AREG | amphiregulin | 0.0524359 |
| ACTG1 | actin gamma 1 | 0.0512995 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0486443 |
| KRT8 | keratin 8, type II | 0.0484865 |
| VEGFA | vascular endothelial growth factor A | 0.0475721 |
| LMO7 | LIM domain 7 | 0.0451014 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0444328 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0435153 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0390912 |
| CALR | calreticulin | 0.0371451 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0369698 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0368417 |
| TMSB4X | thymosin beta 4, X-linked | 0.035863 |
| KRT18 | keratin 18, type I | 0.034405 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.033815 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0307031 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0297385 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.029246 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0282987 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0276942 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0266095 |
| JAG1 | jagged 1 | 0.0246995 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0234112 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0232794 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0227375 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.022285 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0221529 |
| EGFR | epidermal growth factor receptor | 0.0220072 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0219411 |
| DUSP4 | dual specificity phosphatase 4 | 0.0217126 |
| RPL3 | ribosomal protein L3 | 0.0216959 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0215513 |
| PLEC | plectin | 0.0209671 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0207582 |
| MCL1 | myeloid cell leukemia 1 | 0.0204889 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0204875 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0201823 |
| FLNB | filamin B, beta | 0.0200965 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.020024 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0191962 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0190268 |
| MUC13 | mucin 13, cell surface associated | 0.018995 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0189724 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0183988 |
| ADM | adrenomedullin | 0.0181407 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0181108 |
| POTEF | POTE ankyrin domain family, member F | 0.017673 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0175488 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0174925 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0174868 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0171785 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0171388 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0168774 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0167714 |
| MYO1E | myosin IE | 0.0165043 |
| TPM3 | tropomyosin 3 | 0.0164351 |
| FLNA | filamin A, alpha | 0.0163995 |
| SEPTIN9 | septin 9 | 0.0162942 |
| CADPS | Ca++-dependent secretion activator | 0.01616 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0161598 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0160081 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0159813 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0158971 |
| MT2A | metallothionein 2A | 0.0154491 |
| TPM4 | tropomyosin 4 | 0.0150709 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0150618 |
| PDE10A | phosphodiesterase 10A | 0.0149499 |
| SIM2 | single-minded family bHLH transcription factor 2 | 0.0146467 |
| PDZD8 | PDZ domain containing 8 | 0.0145021 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0142996 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0142095 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0136029 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0135851 |
| INTS6 | integrator complex subunit 6 | 0.013445 |
| LDHA | lactate dehydrogenase A | 0.0133356 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0132713 |
| RPN1 | ribophorin I | 0.0130658 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0128982 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0128703 |
| LAMA4 | laminin, alpha 4 | 0.0126327 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0126176 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0126134 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0125437 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0123492 |
| FOSL1 | FOS-like antigen 1 | 0.0122565 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.012242 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0120629 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0118019 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0117322 |
| LUZP1 | leucine zipper protein 1 | 0.0117224 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.011626 |
| SMAD3 | SMAD family member 3 | 0.0115965 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0115785 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.226648 |
| NPSR1 | neuropeptide S receptor 1 | -0.10393 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0913739 |
| RPS6 | ribosomal protein S6 | -0.0632503 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0619661 |
| GOLGA4 | golgin A4 | -0.059236 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0580111 |
| RPLP1 | ribosomal protein, large, P1 | -0.0580011 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0578933 |
| RPL34 | ribosomal protein L34 | -0.0569442 |
| GPHN | gephyrin | -0.0524806 |
| PTMA | prothymosin, alpha | -0.052241 |
| RPLP0 | ribosomal protein, large, P0 | -0.0517022 |
| RBM39 | RNA binding motif protein 39 | -0.0511225 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0469785 |
| MED13L | mediator complex subunit 13-like | -0.0468815 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0453578 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0448731 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0432284 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0430953 |
| RPL12 | ribosomal protein L12 | -0.0427053 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.04269 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0416073 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0410077 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0409859 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0406397 |
| RPL27A | ribosomal protein L27a | -0.0404438 |
| RPS27A | ribosomal protein S27a | -0.0393003 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0391351 |
| WDR45B | WD repeat domain 45B | -0.0380753 |
| RPS12 | ribosomal protein S12 | -0.0375177 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0373117 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0370137 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0370061 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0363778 |
| GDF15 | growth differentiation factor 15 | -0.0361268 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0358196 |
| NF1 | neurofibromin 1 | -0.0352378 |
| RPL26 | ribosomal protein L26 | -0.0351025 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0347416 |
| RPS8 | ribosomal protein S8 | -0.0342711 |
| RPL13A | ribosomal protein L13a | -0.0341565 |
| SERINC5 | serine incorporator 5 | -0.0341553 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0340352 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0340296 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0334758 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0333198 |
| RPS25 | ribosomal protein S25 | -0.0328727 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0325804 |
| RPS24 | ribosomal protein S24 | -0.0325614 |
| RPLP2 | ribosomal protein, large, P2 | -0.0324255 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.032109 |
| SBF2 | SET binding factor 2 | -0.0319574 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0316595 |
| CANX | calnexin | -0.0315735 |
| COG5 | component of oligomeric golgi complex 5 | -0.0312451 |
| RPL35A | ribosomal protein L35a | -0.031228 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0309629 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0308894 |
| RPL37 | ribosomal protein L37 | -0.0306229 |
| ZNF292 | zinc finger protein 292 | -0.0303471 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0300122 |
| SETD5 | SET domain containing 5 | -0.0299277 |
| RPL37A | ribosomal protein L37a | -0.0299001 |
| RPS16 | ribosomal protein S16 | -0.0298697 |
| S100A6 | S100 calcium binding protein A6 | -0.029754 |
| MAP4 | microtubule-associated protein 4 | -0.0297369 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0296607 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0295827 |
| RPS2 | ribosomal protein S2 | -0.0293891 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.029089 |
| RNF145 | ring finger protein 145 | -0.0289328 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.028589 |
| TMSB10 | thymosin beta 10 | -0.0284999 |
| RPL11 | ribosomal protein L11 | -0.0284328 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0282706 |
| AGR2 | anterior gradient 2 | -0.028239 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0282385 |
| FAM13A | family with sequence similarity 13, member A | -0.0282342 |
| MATR3 | matrin 3 | -0.0281023 |
| NFIA | nuclear factor I/A | -0.0279191 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0274119 |
| RPS13 | ribosomal protein S13 | -0.0273972 |
| RPS3 | ribosomal protein S3 | -0.0272155 |
| RPS19 | ribosomal protein S19 | -0.0271485 |
| AHNAK | AHNAK nucleoprotein | -0.0271023 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0270371 |
| USP3 | ubiquitin specific peptidase 3 | -0.0269338 |
| OGA | O-GlcNAcase | -0.0266579 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0264089 |
| HMGA1 | high mobility group AT-hook 1 | -0.0263408 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0262385 |
| KPNB1 | karyopherin (importin) beta 1 | -0.026191 |
| RPL23 | ribosomal protein L23 | -0.0261103 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0260237 |
| S100P | S100 calcium binding protein P | -0.0259864 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0257177 |
| MECOM | MDS1 and EVI1 complex locus | -0.0256328 |
| RACK1 | receptor for activated C kinase 1 | -0.0256121 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0255694 |
