| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | IQ 1 perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the IQ 1_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.328012 |
| MT2A | metallothionein 2A | 0.24644 |
| VIM | vimentin | 0.202113 |
| TMSB4X | thymosin beta 4, X-linked | 0.174025 |
| PTMA | prothymosin, alpha | 0.143269 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.141979 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.119191 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.11673 |
| HLA-B | major histocompatibility complex, class I, B | 0.109298 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.107032 |
| TMSB10 | thymosin beta 10 | 0.103446 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0941072 |
| ACTG1 | actin gamma 1 | 0.0865636 |
| CD44 | CD44 molecule (Indian blood group) | 0.0862933 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0834726 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0817958 |
| CAPRIN2 | caprin family member 2 | 0.0752471 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.075145 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0728879 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0711681 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0702364 |
| FMNL2 | formin-like 2 | 0.0693763 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0664667 |
| TP63 | tumor protein p63 | 0.065117 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0632012 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0628094 |
| MT1E | metallothionein 1E | 0.0615475 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0600546 |
| RUNX1 | runt-related transcription factor 1 | 0.0600053 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0573649 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0569595 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0566464 |
| RPL12 | ribosomal protein L12 | 0.0558083 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0547431 |
| B2M | beta-2-microglobulin | 0.0537657 |
| RPL19 | ribosomal protein L19 | 0.0512409 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.049702 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0490745 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0487457 |
| PGK1 | phosphoglycerate kinase 1 | 0.0478881 |
| LDHA | lactate dehydrogenase A | 0.0477279 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0468538 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0467418 |
| CALR | calreticulin | 0.0464404 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0458028 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0440047 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0432158 |
| KRT18 | keratin 18, type I | 0.0429091 |
| APP | amyloid beta (A4) precursor protein | 0.0426995 |
| JUN | jun proto-oncogene | 0.0425051 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0420047 |
| EZR | ezrin | 0.0415782 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0407398 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0402793 |
| ENO1 | enolase 1, (alpha) | 0.0399066 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0394493 |
| TXNIP | thioredoxin interacting protein | 0.0393808 |
| RPS6 | ribosomal protein S6 | 0.0385172 |
| RPL7A | ribosomal protein L7a | 0.0377845 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0377475 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0373851 |
| AREG | amphiregulin | 0.0371031 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0367244 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0360118 |
| ANGPTL4 | angiopoietin-like 4 | 0.0357889 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0354418 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0348972 |
| RNF213 | ring finger protein 213 | 0.0348045 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0347711 |
| SDC4 | syndecan 4 | 0.0347455 |
| EMP1 | epithelial membrane protein 1 | 0.0345306 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0343769 |
| EREG | epiregulin | 0.0340268 |
| PLAU | plasminogen activator, urokinase | 0.0340221 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0339733 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0339317 |
| HOMER1 | homer scaffolding protein 1 | 0.0334719 |
| POTEF | POTE ankyrin domain family, member F | 0.0333877 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0332068 |
| RPS8 | ribosomal protein S8 | 0.032488 |
| RPL36 | ribosomal protein L36 | 0.0324798 |
| PDE10A | phosphodiesterase 10A | 0.0323011 |
| CMIP | c-Maf inducing protein | 0.0319985 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0313516 |
| TPI1 | triosephosphate isomerase 1 | 0.0311675 |
| PODXL | podocalyxin-like | 0.0308242 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0307744 |
| RPS19 | ribosomal protein S19 | 0.0304621 |
| RGS4 | regulator of G-protein signaling 4 | 0.0303444 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0303134 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0302773 |
| RPS3 | ribosomal protein S3 | 0.029866 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0298531 |
| AHNAK | AHNAK nucleoprotein | 0.0297026 |
| RACK1 | receptor for activated C kinase 1 | 0.0296265 |
| EGR1 | early growth response 1 | 0.0295201 |
| RPS12 | ribosomal protein S12 | 0.0294109 |
| MT1X | metallothionein 1X | 0.029034 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0288823 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.028695 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0260889 |
| COL5A2 | collagen, type V, alpha 2 | -0.0161526 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0150712 |
| RTN4 | reticulon 4 | -0.0144802 |
| FNIP1 | folliculin interacting protein 1 | -0.0139226 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0133671 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.013286 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.013041 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0129672 |
| MAP4 | microtubule-associated protein 4 | -0.0127693 |
| ZNF292 | zinc finger protein 292 | -0.0115205 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0114944 |
| TSC22D2 | TSC22 domain family, member 2 | -0.011417 |
| TFG | TRK-fused gene | -0.0108246 |
| SRP54 | signal recognition particle 54kDa | -0.0107249 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0106964 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0106795 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | -0.0105184 |
| SBF2 | SET binding factor 2 | -0.0104102 |
| EGFR | epidermal growth factor receptor | -0.0103633 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0100692 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00985241 |
| ANKRD28 | ankyrin repeat domain 28 | -0.00947394 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.00947022 |
| TNS3 | tensin 3 | -0.00945114 |
| ANK2 | ankyrin 2, neuronal | -0.00944457 |
| WASF2 | WAS protein family, member 2 | -0.00943542 |
| TFB1M | transcription factor B1, mitochondrial | -0.00941234 |
| DENND5B | DENN/MADD domain containing 5B | -0.00936752 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.00895507 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.00883973 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.00873887 |
| WDR27 | WD repeat domain 27 | -0.00860432 |
| CFDP1 | craniofacial development protein 1 | -0.00859893 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00855577 |
| CENPF | centromere protein F, 350/400kDa | -0.00851306 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.00842879 |
| RTN3 | reticulon 3 | -0.00834678 |
| QKI | QKI, KH domain containing, RNA binding | -0.00830442 |
| ATP11B | ATPase, class VI, type 11B | -0.00814857 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.00810348 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0080755 |
| MIS18BP1 | MIS18 binding protein 1 | -0.00799453 |
| LONP2 | lon peptidase 2, peroxisomal | -0.0079605 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.00779899 |
| QSER1 | glutamine and serine rich 1 | -0.00771715 |
| RYK | receptor-like tyrosine kinase | -0.00771054 |
| MYPN | myopalladin | -0.00770437 |
| THOC1 | THO complex 1 | -0.0076958 |
| NEK7 | NIMA-related kinase 7 | -0.00759455 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.007589 |
| EVI5 | ecotropic viral integration site 5 | -0.0075742 |
| ETNK1 | ethanolamine kinase 1 | -0.00748716 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.00744887 |
| EXOC4 | exocyst complex component 4 | -0.00742093 |
| SMAD2 | SMAD family member 2 | -0.0074064 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00739095 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0073715 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.00732643 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.00729619 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.00729612 |
| NABP1 | nucleic acid binding protein 1 | -0.00728167 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.00722459 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.00717265 |
| NCK1 | NCK adaptor protein 1 | -0.00715457 |
| VIRMA | vir like m6A methyltransferase associated | -0.00714141 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.00713681 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.00700906 |
| SCFD1 | sec1 family domain containing 1 | -0.00697713 |
| CDK17 | cyclin-dependent kinase 17 | -0.00696552 |
| ZNF654 | zinc finger protein 654 | -0.00695651 |
| FAR1 | fatty acyl CoA reductase 1 | -0.00695429 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0069404 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00690096 |
| SP3 | Sp3 transcription factor | -0.00688744 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.00686104 |
| ARF4 | ADP-ribosylation factor 4 | -0.00685567 |
| RUFY2 | RUN and FYVE domain containing 2 | -0.00684848 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0068337 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | -0.00682355 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.00680149 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.00678665 |
| ZNF207 | zinc finger protein 207 | -0.00674165 |
| WDR11 | WD repeat domain 11 | -0.00666894 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | -0.00666274 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.00664595 |
| RBM26 | RNA binding motif protein 26 | -0.00664538 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.00655425 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | -0.00650762 |
| RFX7 | regulatory factor X, 7 | -0.00649511 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 | -0.00643076 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0064029 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00638892 |
| RNF145 | ring finger protein 145 | -0.00634475 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.00633703 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0063186 |
| SLC38A6 | solute carrier family 38, member 6 | -0.00629895 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | -0.00624968 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.00623771 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.00622221 |
