| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | IQ 1 perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the IQ 1_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.320188 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.265351 |
| MT2A | metallothionein 2A | 0.174118 |
| GRAMD1B | GRAM domain containing 1B | 0.13735 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.126311 |
| MCL1 | myeloid cell leukemia 1 | 0.0950968 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0802918 |
| CES1 | carboxylesterase 1 | 0.0712258 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0685153 |
| SMAD3 | SMAD family member 3 | 0.0681289 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0660461 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0639202 |
| ACTG1 | actin gamma 1 | 0.063146 |
| LAMA4 | laminin, alpha 4 | 0.0629613 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0622566 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0601136 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0584525 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0574603 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0557799 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0552857 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0525234 |
| SEC61G | Sec61 gamma subunit | 0.0518868 |
| RPS3 | ribosomal protein S3 | 0.0514519 |
| PKM | pyruvate kinase, muscle | 0.0498681 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0496372 |
| FAM13A | family with sequence similarity 13, member A | 0.0482343 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0479627 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0478276 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0437611 |
| AREG | amphiregulin | 0.0426452 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0397754 |
| MAGEA4 | melanoma antigen family A4 | 0.0393776 |
| PLEC | plectin | 0.0387424 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0383037 |
| SDC1 | syndecan 1 | 0.0381075 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0377079 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0357623 |
| TOP1 | topoisomerase (DNA) I | 0.0355341 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0349175 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.034489 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0344469 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0343846 |
| B2M | beta-2-microglobulin | 0.0340647 |
| PTK2 | protein tyrosine kinase 2 | 0.033997 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0325523 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.032375 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.032074 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0320007 |
| FTL | ferritin, light polypeptide | 0.0318554 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0317506 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0315947 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.031573 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0308992 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0307883 |
| ASPH | aspartate beta-hydroxylase | 0.0307092 |
| RPL19 | ribosomal protein L19 | 0.03069 |
| TMSB10 | thymosin beta 10 | 0.0306881 |
| CUL4A | cullin 4A | 0.0304377 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0303 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0302582 |
| SON | SON DNA binding protein | 0.0298981 |
| ENO1 | enolase 1, (alpha) | 0.0298188 |
| YBX3 | Y box binding protein 3 | 0.0296438 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0289197 |
| RNF213 | ring finger protein 213 | 0.0288994 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0285792 |
| HLA-B | major histocompatibility complex, class I, B | 0.0285755 |
| SLTM | SAFB-like, transcription modulator | 0.0285289 |
| TMEM45B | transmembrane protein 45B | 0.0279773 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0277242 |
| SDC4 | syndecan 4 | 0.0274449 |
| RUNX1 | runt-related transcription factor 1 | 0.0272272 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0271936 |
| RPL37A | ribosomal protein L37a | 0.0270467 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0270426 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0268494 |
| RPL35A | ribosomal protein L35a | 0.0263685 |
| RBM25 | RNA binding motif protein 25 | 0.026283 |
| RPL11 | ribosomal protein L11 | 0.0262719 |
| FLNB | filamin B, beta | 0.0260146 |
| S100A10 | S100 calcium binding protein A10 | 0.0258795 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0258732 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0257206 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0252325 |
| POTEF | POTE ankyrin domain family, member F | 0.0251676 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0251525 |
| MACROH2A1 | macroH2A.1 histone | 0.0251403 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0250834 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0249088 |
| MSN | moesin | 0.0248981 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0244391 |
| FOSL1 | FOS-like antigen 1 | 0.0240288 |
| S100A11 | S100 calcium binding protein A11 | 0.0238805 |
| CDCP1 | CUB domain containing protein 1 | 0.0238682 |
| SMYD3 | SET and MYND domain containing 3 | 0.0238445 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0238261 |
| TPM3 | tropomyosin 3 | 0.0237432 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0234418 |
| STC1 | stanniocalcin 1 | 0.0231871 |
| PRDX1 | peroxiredoxin 1 | 0.023041 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.27403 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0864315 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0620365 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0572289 |
| EFNA5 | ephrin-A5 | -0.0542745 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.053987 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0503972 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0499029 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0495474 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0461707 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0437856 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0428764 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0405821 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0397573 |
| LMO7 | LIM domain 7 | -0.0396419 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0391635 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0381417 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0377109 |
| VCL | vinculin | -0.0359952 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0349929 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0332596 |
| INTS6 | integrator complex subunit 6 | -0.0316665 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0305116 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0299008 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0291753 |
| RAB1A | RAB1A, member RAS oncogene family | -0.028572 |
| CUX1 | cut-like homeobox 1 | -0.0285226 |
| MGAT4C | MGAT4 family, member C | -0.0270387 |
| RPS24 | ribosomal protein S24 | -0.0263722 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0257734 |
| AHNAK | AHNAK nucleoprotein | -0.0253093 |
| NABP1 | nucleic acid binding protein 1 | -0.0250546 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0246192 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0245221 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0244469 |
| FBXO11 | F-box protein 11 | -0.0244131 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0241322 |
| CANX | calnexin | -0.0236236 |
| MYO1E | myosin IE | -0.0231138 |
| CCND1 | cyclin D1 | -0.0231091 |
| RPL34 | ribosomal protein L34 | -0.0228716 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0224452 |
| USP53 | ubiquitin specific peptidase 53 | -0.0221423 |
| ANKRD10 | ankyrin repeat domain 10 | -0.02192 |
| HDLBP | high density lipoprotein binding protein | -0.0209558 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0209062 |
| KRT7 | keratin 7, type II | -0.02057 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.020557 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0203052 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0197194 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0193967 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0192786 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0190739 |
| MYO6 | myosin VI | -0.0189299 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.018905 |
| SQSTM1 | sequestosome 1 | -0.0188916 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0187023 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0185505 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0183782 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0183571 |
| GM2A | GM2 ganglioside activator | -0.0182009 |
| CP | ceruloplasmin (ferroxidase) | -0.0177473 |
| AGR2 | anterior gradient 2 | -0.0177224 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0176175 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0175895 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0174648 |
| S100A6 | S100 calcium binding protein A6 | -0.017435 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0173871 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0172328 |
| SPAG9 | sperm associated antigen 9 | -0.01689 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0168895 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0167776 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0166202 |
| MYO5B | myosin VB | -0.0165221 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0163531 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0162625 |
| ARF1 | ADP-ribosylation factor 1 | -0.0162436 |
| SBF2 | SET binding factor 2 | -0.0162434 |
| SMIM14 | small integral membrane protein 14 | -0.0162363 |
| TPD52 | tumor protein D52 | -0.0162093 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0161667 |
| KRT19 | keratin 19, type I | -0.0161441 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0161347 |
| NF1 | neurofibromin 1 | -0.0158547 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0158377 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0158251 |
| SUCO | SUN domain containing ossification factor | -0.0157956 |
| RIGI | RNA sensor RIG-I | -0.0157276 |
| DSG2 | desmoglein 2 | -0.0155471 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0154565 |
| SKIL | SKI-like proto-oncogene | -0.0153947 |
| MCU | mitochondrial calcium uniporter | -0.0152229 |
| CEP350 | centrosomal protein 350kDa | -0.0151354 |
| CHML | choroideremia-like (Rab escort protein 2) | -0.0151305 |
| H1-0 | H1.0 linker histone | -0.0150413 |
| PLSCR1 | phospholipid scramblase 1 | -0.0150281 |
| RIOK3 | RIO kinase 3 | -0.0149269 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.014858 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0147325 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0145632 |
