| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | IQ 1 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the IQ 1_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.163285 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.156357 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.135905 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.133271 |
| VIM | vimentin | 0.119124 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0934305 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0778927 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0743752 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0697593 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0691927 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0662777 |
| TMSB10 | thymosin beta 10 | 0.0654365 |
| LOX | lysyl oxidase | 0.0642834 |
| B2M | beta-2-microglobulin | 0.0605686 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0580042 |
| CDH13 | cadherin 13 | 0.0579787 |
| HMGA2 | high mobility group AT-hook 2 | 0.0575633 |
| VEGFA | vascular endothelial growth factor A | 0.0560665 |
| STC1 | stanniocalcin 1 | 0.0553984 |
| LOXL2 | lysyl oxidase-like 2 | 0.0520749 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0498603 |
| FAM20C | family with sequence similarity 20, member C | 0.0489871 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.048506 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0478464 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0464896 |
| GLCCI1 | glucocorticoid induced 1 | 0.0452048 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.042498 |
| TMSB4X | thymosin beta 4, X-linked | 0.04247 |
| SEPTIN9 | septin 9 | 0.0406105 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0404109 |
| ADM | adrenomedullin | 0.039144 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0388914 |
| ANGPTL4 | angiopoietin-like 4 | 0.0388438 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0385111 |
| NRG1 | neuregulin 1 | 0.0379965 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0379955 |
| MT2A | metallothionein 2A | 0.0379381 |
| TGFB1 | transforming growth factor, beta 1 | 0.0371565 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0366821 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0362105 |
| CD44 | CD44 molecule (Indian blood group) | 0.0358967 |
| HLA-B | major histocompatibility complex, class I, B | 0.0353122 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0350861 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0349004 |
| AADAC | arylacetamide deacetylase | 0.0348699 |
| RPS19 | ribosomal protein S19 | 0.0339853 |
| PKM | pyruvate kinase, muscle | 0.0338604 |
| RNF213 | ring finger protein 213 | 0.0338392 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0325022 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0323102 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0321712 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0319681 |
| FTL | ferritin, light polypeptide | 0.0317395 |
| NTN4 | netrin 4 | 0.0311639 |
| MTSS1 | metastasis suppressor 1 | 0.0309312 |
| CA12 | carbonic anhydrase XII | 0.0307627 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0305811 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0305457 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0303885 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0302351 |
| RPL31 | ribosomal protein L31 | 0.030178 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.030126 |
| LDHA | lactate dehydrogenase A | 0.0299633 |
| ASPH | aspartate beta-hydroxylase | 0.0299034 |
| NAV1 | neuron navigator 1 | 0.0295213 |
| ECE1 | endothelin converting enzyme 1 | 0.0293512 |
| NAV2 | neuron navigator 2 | 0.0291413 |
| INTS6 | integrator complex subunit 6 | 0.0290087 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0285805 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0277301 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.027633 |
| IFI44L | interferon-induced protein 44-like | 0.0275961 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0274519 |
| MYO10 | myosin X | 0.0270415 |
| TGM2 | transglutaminase 2 | 0.0267472 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0266597 |
| SFTPA2 | surfactant protein A2 | 0.0262155 |
| ENO1 | enolase 1, (alpha) | 0.025973 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0258464 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0256222 |
| RPL7A | ribosomal protein L7a | 0.025469 |
| RPS8 | ribosomal protein S8 | 0.0252864 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0251632 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0249249 |
| RPS17 | ribosomal protein S17 | 0.0248253 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.024719 |
| CLMP | CXADR-like membrane protein | 0.0246105 |
| RPL19 | ribosomal protein L19 | 0.0244935 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0243755 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0242812 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0240214 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0236969 |
| FBN1 | fibrillin 1 | 0.023552 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0230532 |
| RPS29 | ribosomal protein S29 | 0.0226601 |
| RPL37A | ribosomal protein L37a | 0.022527 |
| MCL1 | myeloid cell leukemia 1 | 0.0224246 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0223633 |
| C1R | complement component 1, r subcomponent | 0.0221458 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0220278 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.17692 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101822 |
| RBM39 | RNA binding motif protein 39 | -0.0763853 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.071661 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.064979 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0621389 |
| GOLGA4 | golgin A4 | -0.0600226 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0498136 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0411856 |
| OGA | O-GlcNAcase | -0.0394237 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0373518 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0339864 |
| ZNF292 | zinc finger protein 292 | -0.0329223 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0328887 |
| NCOA7 | nuclear receptor coactivator 7 | -0.032733 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0321844 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0306925 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0285208 |
| ATP13A3 | ATPase type 13A3 | -0.0283584 |
| SPAG9 | sperm associated antigen 9 | -0.0277753 |
| OSMR | oncostatin M receptor | -0.0270175 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0270026 |
| SBF2 | SET binding factor 2 | -0.0259241 |
| USP3 | ubiquitin specific peptidase 3 | -0.0257287 |
| SRP54 | signal recognition particle 54kDa | -0.0255985 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0252397 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0249085 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.024601 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0244154 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0236769 |
| COG5 | component of oligomeric golgi complex 5 | -0.0236066 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0232987 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0231073 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0228003 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0222764 |
| USP34 | ubiquitin specific peptidase 34 | -0.0220638 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0218871 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0217023 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0216142 |
| MORF4L2 | mortality factor 4 like 2 | -0.0215613 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0215097 |
| CD109 | CD109 molecule | -0.0214667 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.020999 |
| CANX | calnexin | -0.020973 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.020963 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0208672 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0207377 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0206401 |
| TXNRD1 | thioredoxin reductase 1 | -0.0205854 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0202961 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0200929 |
| NBAS | neuroblastoma amplified sequence | -0.0197379 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0196343 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0196154 |
| NF1 | neurofibromin 1 | -0.0195086 |
| FOXO3 | forkhead box O3 | -0.0194409 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0193915 |
| GPC6 | glypican 6 | -0.0192463 |
| YME1L1 | YME1-like 1 ATPase | -0.0191356 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0191316 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0190751 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0188361 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0188193 |
| XPO1 | exportin 1 | -0.0186138 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0184579 |
| FRMD5 | FERM domain containing 5 | -0.0184429 |
| VMP1 | vacuole membrane protein 1 | -0.0183863 |
| SUCO | SUN domain containing ossification factor | -0.0183156 |
| NEK7 | NIMA-related kinase 7 | -0.0182753 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.0179258 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0179123 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0178736 |
| RTN4 | reticulon 4 | -0.0178331 |
| PHIP | pleckstrin homology domain interacting protein | -0.0177957 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0177896 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0176937 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0176022 |
| POU2F1 | POU class 2 homeobox 1 | -0.0174927 |
| AHR | aryl hydrocarbon receptor | -0.0173397 |
| PRELID2 | PRELI domain containing 2 | -0.0172817 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0172354 |
| JMJD1C | jumonji domain containing 1C | -0.017185 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.016982 |
| ARF4 | ADP-ribosylation factor 4 | -0.0169712 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0168963 |
| MYOF | myoferlin | -0.0168581 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0167864 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0166983 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.016624 |
| CDK17 | cyclin-dependent kinase 17 | -0.0164786 |
| PARD3 | par-3 family cell polarity regulator | -0.0164634 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0164431 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0160953 |
| CEP95 | centrosomal protein 95kDa | -0.015962 |
| SEC24A | SEC24 family member A | -0.0158363 |
| NKTR | natural killer cell triggering receptor | -0.0158177 |
| ZFR | zinc finger RNA binding protein | -0.0158046 |
| POM121C | POM121 transmembrane nucleoporin C | -0.015716 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0154849 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0154804 |
