| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | IQ 1 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the IQ 1_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.147803 |
| DSCAM | Down syndrome cell adhesion molecule | 0.1477 |
| FN1 | fibronectin 1 | 0.12343 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.115747 |
| EXT1 | exostosin glycosyltransferase 1 | 0.106496 |
| MYOF | myoferlin | 0.105895 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.101529 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.100687 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0945595 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0897345 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0884344 |
| FNIP1 | folliculin interacting protein 1 | 0.0878428 |
| MYO1E | myosin IE | 0.0836653 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0831006 |
| MUC13 | mucin 13, cell surface associated | 0.0736567 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0723384 |
| FLNB | filamin B, beta | 0.0708881 |
| LAMC2 | laminin, gamma 2 | 0.0702651 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0698826 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0694719 |
| CXXC1 | CXXC finger protein 1 | 0.0661726 |
| YTHDC1 | YTH domain containing 1 | 0.0639115 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0630121 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0622279 |
| BRD2 | bromodomain containing 2 | 0.0618987 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0610449 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0600866 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0596417 |
| DSPP | dentin sialophosphoprotein | 0.0585157 |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.0584775 |
| EXOC4 | exocyst complex component 4 | 0.0563725 |
| CSTB | cystatin B (stefin B) | 0.0557155 |
| ATP11A | ATPase, class VI, type 11A | 0.0554979 |
| SMYD3 | SET and MYND domain containing 3 | 0.0531486 |
| INTS6 | integrator complex subunit 6 | 0.0528739 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0505107 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0468668 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0465997 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0465735 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.046505 |
| ACTN4 | actinin, alpha 4 | 0.046415 |
| TPCN1 | two pore segment channel 1 | 0.0463841 |
| PURA | purine-rich element binding protein A | 0.0462316 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0450988 |
| NDRG1 | N-myc downstream regulated 1 | 0.0447564 |
| SON | SON DNA binding protein | 0.0445304 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0442609 |
| VIM | vimentin | 0.0439532 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0438393 |
| PTK2 | protein tyrosine kinase 2 | 0.0437654 |
| CD44 | CD44 molecule (Indian blood group) | 0.0424085 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0423414 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0420857 |
| RAD21 | RAD21 homolog (S. pombe) | 0.04118 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0409952 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0407986 |
| RPN2 | ribophorin II | 0.0406033 |
| ACTG1 | actin gamma 1 | 0.0401169 |
| MLPH | melanophilin | 0.0399748 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0384705 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0382174 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.038091 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0380779 |
| FTL | ferritin, light polypeptide | 0.0377853 |
| CD46 | CD46 molecule, complement regulatory protein | 0.037233 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0370159 |
| MED13L | mediator complex subunit 13-like | 0.0368505 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0367007 |
| CCND1 | cyclin D1 | 0.036328 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0357396 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.035686 |
| GOLGA4 | golgin A4 | 0.0355476 |
| STC2 | stanniocalcin 2 | 0.0353424 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.035202 |
| RBM47 | RNA binding motif protein 47 | 0.0345292 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0344567 |
| TC2N | tandem C2 domains, nuclear | 0.034412 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0343907 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.034351 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0342684 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0340202 |
| STK40 | serine/threonine kinase 40 | 0.0339869 |
| MORF4L2 | mortality factor 4 like 2 | 0.0338622 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0338381 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0338038 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0336907 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0335541 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0334339 |
| GLCCI1 | glucocorticoid induced 1 | 0.0333245 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0332623 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0330532 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0327036 |
| CRY1 | cryptochrome circadian clock 1 | 0.0323741 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0323394 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0321226 |
| LDHA | lactate dehydrogenase A | 0.0321077 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0320523 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.0320258 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0318752 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0314092 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.112191 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.107977 |
| ATOSA | atos homolog A | -0.0998984 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0920679 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0912083 |
| TXNRD1 | thioredoxin reductase 1 | -0.0860028 |
| TXNIP | thioredoxin interacting protein | -0.0819663 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0793945 |
| EGFR | epidermal growth factor receptor | -0.0783278 |
| SVIL | supervillin | -0.0750935 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0734206 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0716969 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0695375 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0685707 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.064365 |
| HMGA2 | high mobility group AT-hook 2 | -0.0641058 |
| NF1 | neurofibromin 1 | -0.0632605 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0632535 |
| ASPH | aspartate beta-hydroxylase | -0.0599637 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0584713 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0561815 |
| AHNAK | AHNAK nucleoprotein | -0.0549256 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0544172 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0541972 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0533406 |
| OGA | O-GlcNAcase | -0.0528 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0519315 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0518465 |
| STC1 | stanniocalcin 1 | -0.0515678 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0515195 |
| FMNL2 | formin-like 2 | -0.0505577 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0504359 |
| CLMP | CXADR-like membrane protein | -0.0503866 |
| FOXP1 | forkhead box P1 | -0.0503639 |
| NEBL | nebulette | -0.0495933 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0489489 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0488562 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0487608 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0479527 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0475699 |
| RPS6 | ribosomal protein S6 | -0.0475541 |
| SPAG9 | sperm associated antigen 9 | -0.0474803 |
| TULP4 | tubby like protein 4 | -0.0473519 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0463473 |
| CCNI | cyclin I | -0.0462497 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.04614 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0456021 |
| BCL2L1 | BCL2-like 1 | -0.0450854 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0450561 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.045047 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0450204 |
| DUSP16 | dual specificity phosphatase 16 | -0.0448357 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0443075 |
| ITGB4 | integrin, beta 4 | -0.0441843 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0440476 |
| CCNY | cyclin Y | -0.0439985 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0436293 |
| SSH2 | slingshot protein phosphatase 2 | -0.0431823 |
| ABHD17C | abhydrolase domain containing 17C | -0.0421507 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0408412 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0405851 |
| MED13 | mediator complex subunit 13 | -0.0405289 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0401918 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0400271 |
| ZFHX3 | zinc finger homeobox 3 | -0.0398663 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0389842 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.038908 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0388882 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0386984 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.038006 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0378533 |
| RAD51B | RAD51 paralog B | -0.0377853 |
| PTMA | prothymosin, alpha | -0.0375293 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0372462 |
| ZNF292 | zinc finger protein 292 | -0.0370251 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.036887 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0368211 |
| YAP1 | Yes-associated protein 1 | -0.036575 |
| PRKCA | protein kinase C, alpha | -0.0361136 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0357993 |
| PDS5A | PDS5 cohesin associated factor A | -0.0354874 |
| EGR1 | early growth response 1 | -0.0350655 |
| EFNA5 | ephrin-A5 | -0.0350262 |
| TCF12 | transcription factor 12 | -0.034983 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0345924 |
| TNPO1 | transportin 1 | -0.0341751 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0339118 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0338748 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0337363 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0337174 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0337078 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0334653 |
| USP3 | ubiquitin specific peptidase 3 | -0.0332595 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0331467 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0331403 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0330462 |
| ERBIN | erbb2 interacting protein | -0.0328139 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0327972 |
| RPL26 | ribosomal protein L26 | -0.0327135 |
| KIF13B | kinesin family member 13B | -0.0324991 |
