| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | IQ 1 perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the IQ 1_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACTG1 | actin gamma 1 | 0.198053 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.187109 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.171408 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.1239 |
| NDRG1 | N-myc downstream regulated 1 | 0.111693 |
| LAMC2 | laminin, gamma 2 | 0.100686 |
| SDC4 | syndecan 4 | 0.0932485 |
| LAMB3 | laminin, beta 3 | 0.0907526 |
| FN1 | fibronectin 1 | 0.0889184 |
| POTEF | POTE ankyrin domain family, member F | 0.0883213 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0877266 |
| LMO7 | LIM domain 7 | 0.0847441 |
| PLEC | plectin | 0.0777063 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0753244 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0618319 |
| VEGFA | vascular endothelial growth factor A | 0.0613842 |
| TMSB4X | thymosin beta 4, X-linked | 0.0600184 |
| EGR1 | early growth response 1 | 0.0592655 |
| SMAD3 | SMAD family member 3 | 0.0578641 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0558372 |
| ASPH | aspartate beta-hydroxylase | 0.0551444 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0513301 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0504011 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0499518 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0491197 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0466899 |
| KRT8 | keratin 8, type II | 0.0461591 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0455487 |
| MT2A | metallothionein 2A | 0.0435564 |
| MAP1B | microtubule-associated protein 1B | 0.0434402 |
| G0S2 | G0/G1 switch 2 | 0.0431888 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0430056 |
| MSN | moesin | 0.042791 |
| MYO5B | myosin VB | 0.0422149 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0415955 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0412379 |
| CALR | calreticulin | 0.0396946 |
| AREG | amphiregulin | 0.0395642 |
| KRT18 | keratin 18, type I | 0.0393771 |
| DTNA | dystrobrevin, alpha | 0.0385297 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0379185 |
| ADM | adrenomedullin | 0.0375725 |
| CTSB | cathepsin B | 0.0374916 |
| RBM25 | RNA binding motif protein 25 | 0.0371609 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0367758 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0364447 |
| FLNA | filamin A, alpha | 0.0361761 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0358125 |
| MCL1 | myeloid cell leukemia 1 | 0.0357856 |
| CD44 | CD44 molecule (Indian blood group) | 0.0356777 |
| ERBIN | erbb2 interacting protein | 0.0354736 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0351773 |
| ANXA2 | annexin A2 | 0.0349272 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0346658 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0344236 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0338329 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0336249 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.03314 |
| TMSB10 | thymosin beta 10 | 0.0322336 |
| KRT7 | keratin 7, type II | 0.0318329 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0318278 |
| RCOR1 | REST corepressor 1 | 0.0313314 |
| TPM3 | tropomyosin 3 | 0.0313211 |
| CDCP1 | CUB domain containing protein 1 | 0.0310263 |
| AHNAK | AHNAK nucleoprotein | 0.030976 |
| TJP1 | tight junction protein 1 | 0.0304785 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0298579 |
| DUSP6 | dual specificity phosphatase 6 | 0.0297504 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0295703 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0293953 |
| PLAU | plasminogen activator, urokinase | 0.0290243 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0288835 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0287908 |
| BRD2 | bromodomain containing 2 | 0.0284882 |
| DSPP | dentin sialophosphoprotein | 0.0284261 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0283957 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0283451 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0280714 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0277407 |
| JUP | junction plakoglobin | 0.0272724 |
| EZR | ezrin | 0.0270655 |
| FAM107B | family with sequence similarity 107, member B | 0.0268247 |
| PKM | pyruvate kinase, muscle | 0.0267518 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0266472 |
| TOP1 | topoisomerase (DNA) I | 0.0265277 |
| RPN1 | ribophorin I | 0.0263474 |
| GRB10 | growth factor receptor-bound protein 10 | 0.026171 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0256833 |
| ARRDC3 | arrestin domain containing 3 | 0.025566 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0252749 |
| CLDN4 | claudin 4 | 0.0249278 |
| KRT19 | keratin 19, type I | 0.0247309 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0242679 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0242493 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.023974 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0235451 |
| ANO6 | anoctamin 6 | 0.0235205 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0235073 |
| RASAL2 | RAS protein activator like 2 | 0.0233534 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0232911 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.106348 |
| RPL35A | ribosomal protein L35a | -0.06358 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0608199 |
| RPL34 | ribosomal protein L34 | -0.0488177 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0472911 |
| FTL | ferritin, light polypeptide | -0.0461063 |
| RPS25 | ribosomal protein S25 | -0.0419883 |
| FBXO32 | F-box protein 32 | -0.0405697 |
| RPLP0 | ribosomal protein, large, P0 | -0.0383595 |
| PTMA | prothymosin, alpha | -0.0382025 |
| SQSTM1 | sequestosome 1 | -0.0380857 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0368738 |
| CANX | calnexin | -0.0361135 |
| RPS23 | ribosomal protein S23 | -0.0358214 |
| RPS16 | ribosomal protein S16 | -0.0348687 |
| RPL37 | ribosomal protein L37 | -0.0343667 |
| RPS8 | ribosomal protein S8 | -0.0341538 |
| RPL9 | ribosomal protein L9 | -0.033579 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0323623 |
| RPS6 | ribosomal protein S6 | -0.0306094 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0305848 |
| RPL31 | ribosomal protein L31 | -0.0300641 |
| RPL11 | ribosomal protein L11 | -0.0291643 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.029121 |
| RPL37A | ribosomal protein L37a | -0.0289993 |
| RPLP1 | ribosomal protein, large, P1 | -0.028795 |
| RPL30 | ribosomal protein L30 | -0.0287402 |
| VIM | vimentin | -0.0286431 |
| RPS29 | ribosomal protein S29 | -0.0285547 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0278678 |
| RPS24 | ribosomal protein S24 | -0.0276534 |
| ZNF292 | zinc finger protein 292 | -0.0269309 |
| RPL27A | ribosomal protein L27a | -0.0268833 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0267986 |
| RPS12 | ribosomal protein S12 | -0.0265092 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0254329 |
| RPS27A | ribosomal protein S27a | -0.0248537 |
| HMGB2 | high mobility group box 2 | -0.0242199 |
| RPS11 | ribosomal protein S11 | -0.024076 |
| KLHL24 | kelch-like family member 24 | -0.023694 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0236128 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0235891 |
| RPS20 | ribosomal protein S20 | -0.0234855 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0232996 |
| AOPEP | aminopeptidase O (putative) | -0.0232579 |
| CTSD | cathepsin D | -0.0231627 |
| RPS13 | ribosomal protein S13 | -0.0229431 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0227198 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0218368 |
| RPS5 | ribosomal protein S5 | -0.0215801 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | -0.021524 |
| RPL15 | ribosomal protein L15 | -0.0211014 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.021059 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0209071 |
| TFG | TRK-fused gene | -0.0204314 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0201329 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0199595 |
| RPL12 | ribosomal protein L12 | -0.0199062 |
| FBXO34 | F-box protein 34 | -0.0195735 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0194192 |
| RPL38 | ribosomal protein L38 | -0.0188726 |
| STEAP4 | STEAP family member 4 | -0.0187571 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0183163 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0181188 |
| RPLP2 | ribosomal protein, large, P2 | -0.0180695 |
| MATR3 | matrin 3 | -0.0179154 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0176705 |
| RPS27 | ribosomal protein S27 | -0.0174169 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.0173199 |
| RTN3 | reticulon 3 | -0.0172454 |
| RPL7 | ribosomal protein L7 | -0.0172268 |
| TMEM123 | transmembrane protein 123 | -0.0170696 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0170035 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0167753 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0167018 |
| PHF3 | PHD finger protein 3 | -0.0166278 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0166117 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0165985 |
| GNAS | GNAS complex locus | -0.016447 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0164261 |
| FHIT | fragile histidine triad | -0.016311 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0162419 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0161815 |
| RPL26 | ribosomal protein L26 | -0.0160933 |
| RBM39 | RNA binding motif protein 39 | -0.0160634 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0159343 |
| PPCDC | phosphopantothenoylcysteine decarboxylase | -0.0157811 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0157469 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.015652 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0155786 |
| RPS10 | ribosomal protein S10 | -0.015451 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0154457 |
| RPL28 | ribosomal protein L28 | -0.0154357 |
| FOXN3 | forkhead box N3 | -0.0152434 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0151355 |
| RPL36A | ribosomal protein L36a | -0.0150828 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0149833 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0149551 |
| RLF | rearranged L-myc fusion | -0.0148625 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0147527 |
