| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | IQ 1 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the IQ 1_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.0981835 |
| CALR | calreticulin | 0.0922307 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0884233 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0846031 |
| ACTG1 | actin gamma 1 | 0.0748027 |
| TMSB4X | thymosin beta 4, X-linked | 0.054514 |
| FOXP2 | forkhead box P2 | 0.0473183 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0466601 |
| HDAC9 | histone deacetylase 9 | 0.0459129 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0420028 |
| MKI67 | marker of proliferation Ki-67 | 0.0409307 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0402652 |
| RPL3 | ribosomal protein L3 | 0.0401973 |
| CCN2 | cellular communication network factor 2 | 0.0397422 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0395921 |
| YBX1 | Y box binding protein 1 | 0.0394204 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0391955 |
| APP | amyloid beta (A4) precursor protein | 0.0388718 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.036941 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0365851 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0364178 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0360076 |
| RNF213 | ring finger protein 213 | 0.0358274 |
| TPR | translocated promoter region, nuclear basket protein | 0.0357469 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0355384 |
| TEX11 | testis expressed 11 | 0.0350189 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0343169 |
| PCDH7 | protocadherin 7 | 0.03392 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0331324 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0330973 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0329627 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0324606 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0323209 |
| FOXG1 | forkhead box G1 | 0.0316568 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0314037 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0307286 |
| NTM | neurotrimin | 0.0302048 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | 0.029549 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.029393 |
| TMEM165 | transmembrane protein 165 | 0.0292776 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0281772 |
| CALU | calumenin | 0.0278129 |
| SMYD3 | SET and MYND domain containing 3 | 0.0276958 |
| FNDC3A | fibronectin type III domain containing 3A | 0.027515 |
| SFTPA2 | surfactant protein A2 | 0.0273137 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0271321 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0270669 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0269482 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0268949 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0265273 |
| JAG1 | jagged 1 | 0.0264228 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0263951 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0261812 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.026093 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0260701 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0258336 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0256308 |
| GPC4 | glypican 4 | 0.0252201 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0249445 |
| BNC2 | basonuclin 2 | 0.024636 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0239903 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0238915 |
| CCNY | cyclin Y | 0.0238911 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0237904 |
| WWOX | WW domain containing oxidoreductase | 0.0237796 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0237677 |
| ADM | adrenomedullin | 0.0237537 |
| SMAD3 | SMAD family member 3 | 0.0236862 |
| ZNF148 | zinc finger protein 148 | 0.0236635 |
| NUDC | nudC nuclear distribution protein | 0.0235622 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0235582 |
| GPR141 | G protein-coupled receptor 141 | 0.0235179 |
| ENAH | enabled homolog (Drosophila) | 0.023334 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0232409 |
| BLCAP | bladder cancer associated protein | 0.0232003 |
| CENPF | centromere protein F, 350/400kDa | 0.0230499 |
| FOXN3 | forkhead box N3 | 0.0229756 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0229535 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0224896 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0224007 |
| FLNA | filamin A, alpha | 0.0223504 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0223098 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.022239 |
| PKP4 | plakophilin 4 | 0.0221978 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0221463 |
| KIF5B | kinesin family member 5B | 0.0221337 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0220613 |
| NELL2 | NEL-like 2 (chicken) | 0.0220268 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0219775 |
| ZNF91 | zinc finger protein 91 | 0.0219422 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0217995 |
| NONO | non-POU domain containing, octamer-binding | 0.021664 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0214479 |
| HYOU1 | hypoxia up-regulated 1 | 0.0212565 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0211458 |
| SNX6 | sorting nexin 6 | 0.0210785 |
| NOTCH2 | notch 2 | 0.0209951 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.020961 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0208384 |
| KIF13A | kinesin family member 13A | 0.0208036 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.2174 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.134901 |
| GPC3 | glypican 3 | -0.094556 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0875177 |
| PTMA | prothymosin, alpha | -0.0787303 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0771474 |
| TMSB10 | thymosin beta 10 | -0.0727253 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0680494 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0679541 |
| PFN1 | profilin 1 | -0.066681 |
| PCDH9 | protocadherin 9 | -0.0654839 |
| RPLP1 | ribosomal protein, large, P1 | -0.0642077 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0630707 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0620014 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0611279 |
| SPAG9 | sperm associated antigen 9 | -0.0601401 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0575462 |
| PHIP | pleckstrin homology domain interacting protein | -0.056864 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0565374 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0542147 |
| SRP54 | signal recognition particle 54kDa | -0.0534173 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0533713 |
| RPS6 | ribosomal protein S6 | -0.0530375 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0523056 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0508745 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0507669 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0505823 |
| GNAS | GNAS complex locus | -0.0500198 |
| ZNF292 | zinc finger protein 292 | -0.0498118 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0465714 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0465692 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0458441 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0456819 |
| COL1A2 | collagen, type I, alpha 2 | -0.0444801 |
| MAP4 | microtubule-associated protein 4 | -0.0442828 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0441348 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0438923 |
| HMGB1 | high mobility group box 1 | -0.0434776 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0434035 |
| NOP58 | NOP58 ribonucleoprotein | -0.0432227 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0431284 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0426511 |
| PDS5A | PDS5 cohesin associated factor A | -0.0426467 |
| RPS16 | ribosomal protein S16 | -0.0424323 |
| FBXO11 | F-box protein 11 | -0.0416734 |
| PGK1 | phosphoglycerate kinase 1 | -0.0415338 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0413567 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0404683 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0401736 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0397859 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0393759 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0392303 |
| HMGA1 | high mobility group AT-hook 1 | -0.0390841 |
| CXADR | coxsackie virus and adenovirus receptor | -0.038949 |
| RYBP | RING1 and YY1 binding protein | -0.0379299 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0363897 |
| RPL37 | ribosomal protein L37 | -0.0358574 |
| RTN3 | reticulon 3 | -0.0357607 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0351317 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0351302 |
| H1-0 | H1.0 linker histone | -0.0350512 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0350218 |
| RPL19 | ribosomal protein L19 | -0.0349442 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0347322 |
| USP53 | ubiquitin specific peptidase 53 | -0.0346107 |
| ABI2 | abl-interactor 2 | -0.0341904 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0340797 |
| RAI1 | retinoic acid induced 1 | -0.0339884 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0338945 |
| KLHL5 | kelch-like family member 5 | -0.0338641 |
| NRXN1 | neurexin 1 | -0.0338618 |
| PLPP1 | phospholipid phosphatase 1 | -0.0338326 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0336057 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0335596 |
| RPS24 | ribosomal protein S24 | -0.0334015 |
| MPG | N-methylpurine-DNA glycosylase | -0.033313 |
| NKTR | natural killer cell triggering receptor | -0.0331304 |
| CANX | calnexin | -0.0329838 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0329297 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0328851 |
| ZNF217 | zinc finger protein 217 | -0.0328102 |
| S100A10 | S100 calcium binding protein A10 | -0.0326249 |
| RPLP0 | ribosomal protein, large, P0 | -0.0325495 |
| RPS21 | ribosomal protein S21 | -0.0320775 |
| RPL35A | ribosomal protein L35a | -0.0320652 |
| CDC73 | cell division cycle 73 | -0.0319625 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0313854 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0313286 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0312673 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0311922 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0310828 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.030883 |
| RPL11 | ribosomal protein L11 | -0.0306656 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.03064 |
| RPL34 | ribosomal protein L34 | -0.0303091 |
| ZNF385D | zinc finger protein 385D | -0.0303057 |
| RPLP2 | ribosomal protein, large, P2 | -0.0301405 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0299922 |
| SEPTIN7 | septin 7 | -0.0297393 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0296738 |
