| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | IQ 1 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the IQ 1_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.145185 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0924971 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0892534 |
| EGFR | epidermal growth factor receptor | 0.0846618 |
| EZR | ezrin | 0.082479 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0787292 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0725377 |
| PKM | pyruvate kinase, muscle | 0.0660204 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0609637 |
| ANXA1 | annexin A1 | 0.0581907 |
| DUSP4 | dual specificity phosphatase 4 | 0.0572578 |
| MYO5C | myosin VC | 0.0570109 |
| PDGFC | platelet derived growth factor C | 0.055814 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0545025 |
| FOXP1 | forkhead box P1 | 0.0530714 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0526289 |
| RPL3 | ribosomal protein L3 | 0.0496631 |
| PTMA | prothymosin, alpha | 0.0490554 |
| FER1L6 | fer-1-like family member 6 | 0.048258 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0456934 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0451796 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0433455 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0432015 |
| INTS6 | integrator complex subunit 6 | 0.0427193 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0422816 |
| RPL7A | ribosomal protein L7a | 0.0419719 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0410553 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0399437 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0382068 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0364288 |
| VCL | vinculin | 0.0356847 |
| LOXL3 | lysyl oxidase-like 3 | 0.033322 |
| ACTG1 | actin gamma 1 | 0.0332842 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0332304 |
| FBLN2 | fibulin 2 | 0.031806 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0314611 |
| ARHGAP25 | Rho GTPase activating protein 25 | 0.0310396 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.03035 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0299108 |
| POTEF | POTE ankyrin domain family, member F | 0.0297062 |
| ZNF608 | zinc finger protein 608 | 0.0289513 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0289094 |
| MLIP | muscular LMNA-interacting protein | 0.0284144 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0276443 |
| GSE1 | Gse1 coiled-coil protein | 0.0273984 |
| SGMS2 | sphingomyelin synthase 2 | 0.0273961 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0272265 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0269333 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0264202 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0263793 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0262962 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0262053 |
| MYOF | myoferlin | 0.026017 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0254551 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0252587 |
| SMAD3 | SMAD family member 3 | 0.025137 |
| GLI3 | GLI family zinc finger 3 | 0.0245954 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0242758 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0241788 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0236183 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0235802 |
| GLI2 | GLI family zinc finger 2 | 0.023311 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0230585 |
| RSF1 | remodeling and spacing factor 1 | 0.0227073 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.022571 |
| TRIOBP | TRIO and F-actin binding protein | 0.0224817 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0224421 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.021553 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.02146 |
| USP47 | ubiquitin specific peptidase 47 | 0.0214203 |
| AMOTL2 | angiomotin like 2 | 0.0208625 |
| RRM2 | ribonucleotide reductase M2 | 0.0208363 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0207975 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0206934 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0200969 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0200669 |
| PLXNA1 | plexin A1 | 0.0199957 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0199242 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0199148 |
| AEBP2 | AE binding protein 2 | 0.0199032 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0196183 |
| FAT1 | FAT atypical cadherin 1 | 0.0196136 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0196095 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 0.0195049 |
| SMAD6 | SMAD family member 6 | 0.0195045 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0194817 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0193263 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0190788 |
| FLNB | filamin B, beta | 0.0187695 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0187406 |
| PRELID2 | PRELI domain containing 2 | 0.0187332 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0186803 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0184134 |
| RBM5 | RNA binding motif protein 5 | 0.0184083 |
| YAP1 | Yes-associated protein 1 | 0.018389 |
| SON | SON DNA binding protein | 0.0183879 |
| TRIM24 | tripartite motif containing 24 | 0.0183374 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0182365 |
| BRD2 | bromodomain containing 2 | 0.0181967 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0181457 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.183912 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.102191 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0964267 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0949119 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0861579 |
| IGF2 | insulin-like growth factor 2 | -0.0781731 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0723304 |
| S100A6 | S100 calcium binding protein A6 | -0.0701131 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.06832 |
| RBM39 | RNA binding motif protein 39 | -0.0642305 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0601056 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0588954 |
| EVI5 | ecotropic viral integration site 5 | -0.0581529 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0580565 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0579793 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.056504 |
| FTL | ferritin, light polypeptide | -0.055835 |
| ZNF292 | zinc finger protein 292 | -0.055686 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0554097 |
| RPS6 | ribosomal protein S6 | -0.0548596 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0532368 |
| B2M | beta-2-microglobulin | -0.0522419 |
| RPLP0 | ribosomal protein, large, P0 | -0.0476786 |
| RPS27A | ribosomal protein S27a | -0.0450206 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0439025 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0416479 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0414567 |
| RPL28 | ribosomal protein L28 | -0.0414419 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0410842 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0408994 |
| GOLGA4 | golgin A4 | -0.0404418 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0402355 |
| TXNRD1 | thioredoxin reductase 1 | -0.0401474 |
| RPL35A | ribosomal protein L35a | -0.0397307 |
| EFNA5 | ephrin-A5 | -0.0391151 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0390033 |
| CANX | calnexin | -0.0384583 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.037809 |
| RPLP1 | ribosomal protein, large, P1 | -0.0377688 |
| COG5 | component of oligomeric golgi complex 5 | -0.0366393 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0363999 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0362984 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0361331 |
| RPS29 | ribosomal protein S29 | -0.0353998 |
| RPS16 | ribosomal protein S16 | -0.0352667 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0349028 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0348253 |
| PDE10A | phosphodiesterase 10A | -0.0346441 |
| NF1 | neurofibromin 1 | -0.0345991 |
| PGK1 | phosphoglycerate kinase 1 | -0.0343193 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | -0.0342046 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0333536 |
| RPS19 | ribosomal protein S19 | -0.032312 |
| VIM | vimentin | -0.0320282 |
| MSI2 | musashi RNA-binding protein 2 | -0.0317775 |
| RPS11 | ribosomal protein S11 | -0.0314079 |
| RPS24 | ribosomal protein S24 | -0.0308716 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0307254 |
| MATR3 | matrin 3 | -0.0307029 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0305657 |
| USP3 | ubiquitin specific peptidase 3 | -0.0303791 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0302453 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0301456 |
| SBF2 | SET binding factor 2 | -0.0300786 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0300032 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0299291 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0298478 |
| RPS23 | ribosomal protein S23 | -0.0296239 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0295535 |
| NFIA | nuclear factor I/A | -0.0295372 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.029452 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0293445 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0293067 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0292972 |
| RPS5 | ribosomal protein S5 | -0.0292805 |
| XPO1 | exportin 1 | -0.0292153 |
| S100A4 | S100 calcium binding protein A4 | -0.0291411 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0290486 |
| RPS25 | ribosomal protein S25 | -0.0290139 |
| VGLL4 | vestigial-like family member 4 | -0.0285628 |
| PHIP | pleckstrin homology domain interacting protein | -0.0284905 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0283164 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0282647 |
| MAP4 | microtubule-associated protein 4 | -0.0281894 |
| RPL34 | ribosomal protein L34 | -0.0281725 |
| RHOA | ras homolog family member A | -0.0280795 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0277731 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0277704 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0276791 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0276582 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0276453 |
| RNF145 | ring finger protein 145 | -0.0273313 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0273135 |
| RPS2 | ribosomal protein S2 | -0.0272767 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.027276 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.027012 |
| NCKAP1 | NCK-associated protein 1 | -0.0268596 |
| PTK2 | protein tyrosine kinase 2 | -0.0267501 |
| RPL27A | ribosomal protein L27a | -0.0267179 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.026626 |
