| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | IQ 1 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the IQ 1_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.247733 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.211853 |
| MT2A | metallothionein 2A | 0.135333 |
| B2M | beta-2-microglobulin | 0.0963464 |
| HLA-B | major histocompatibility complex, class I, B | 0.0953176 |
| CALR | calreticulin | 0.0927336 |
| SDC4 | syndecan 4 | 0.0783169 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0776784 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0716029 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0707446 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0657782 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.064042 |
| ADM | adrenomedullin | 0.0614903 |
| NDRG1 | N-myc downstream regulated 1 | 0.0603773 |
| ARRDC3 | arrestin domain containing 3 | 0.0530571 |
| TMSB10 | thymosin beta 10 | 0.0482992 |
| VEGFA | vascular endothelial growth factor A | 0.047618 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0417265 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0406508 |
| MCL1 | myeloid cell leukemia 1 | 0.0390838 |
| STC1 | stanniocalcin 1 | 0.038246 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0372406 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.036317 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.035554 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0338914 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0336335 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0332251 |
| FAM13A | family with sequence similarity 13, member A | 0.0327657 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0325174 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0314466 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.031198 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0303407 |
| PLEC | plectin | 0.0303119 |
| ANXA2 | annexin A2 | 0.0297567 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0295704 |
| HDLBP | high density lipoprotein binding protein | 0.0294576 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0282654 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0277083 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0275131 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0267037 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0266334 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0266213 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0257836 |
| LMNA | lamin A/C | 0.0255501 |
| CTSB | cathepsin B | 0.0253488 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0250802 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0245933 |
| CALU | calumenin | 0.0239963 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0237908 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0236481 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0232892 |
| SMAD3 | SMAD family member 3 | 0.022841 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0226147 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0224541 |
| UBC | ubiquitin C | 0.0219291 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0218967 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0218875 |
| PMM2 | phosphomannomutase 2 | 0.0213355 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0212843 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0212411 |
| HLA-A | major histocompatibility complex, class I, A | 0.0211496 |
| TXNIP | thioredoxin interacting protein | 0.0210282 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.0206444 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0206091 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0202652 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0200956 |
| MORF4L2 | mortality factor 4 like 2 | 0.0198928 |
| JAG1 | jagged 1 | 0.019793 |
| HIP1 | huntingtin interacting protein 1 | 0.0197576 |
| LOXL2 | lysyl oxidase-like 2 | 0.0196726 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0196441 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0196084 |
| RPL3 | ribosomal protein L3 | 0.0194047 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0194024 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0193695 |
| EMP1 | epithelial membrane protein 1 | 0.0193608 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.019232 |
| CLINT1 | clathrin interactor 1 | 0.0191587 |
| ANO6 | anoctamin 6 | 0.0191142 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0191105 |
| SETD5 | SET domain containing 5 | 0.0191051 |
| TMSB4X | thymosin beta 4, X-linked | 0.0189338 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0188799 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0181797 |
| APP | amyloid beta (A4) precursor protein | 0.0180304 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0179845 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0177854 |
| SFTPA2 | surfactant protein A2 | 0.0176171 |
| MYO9B | myosin IXB | 0.017492 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0174664 |
| MTPN | myotrophin | 0.0174144 |
| PRELID2 | PRELI domain containing 2 | 0.0173717 |
| PTK2 | protein tyrosine kinase 2 | 0.0172182 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0168639 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0168305 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0167776 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.016651 |
| RBM39 | RNA binding motif protein 39 | 0.0166005 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.0164305 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0163333 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.110114 |
| VIM | vimentin | -0.0745164 |
| POTEF | POTE ankyrin domain family, member F | -0.0695238 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0589869 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0571366 |
| CALD1 | caldesmon 1 | -0.0542066 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0524175 |
| COL1A1 | collagen, type I, alpha 1 | -0.0512512 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0504964 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0460523 |
| COL1A2 | collagen, type I, alpha 2 | -0.0421082 |
| IL6 | interleukin 6 | -0.0402732 |
| CDH13 | cadherin 13 | -0.0342685 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0340001 |
| GLIS3 | GLIS family zinc finger 3 | -0.0334333 |
| TPM1 | tropomyosin 1 (alpha) | -0.0314883 |
| TNS3 | tensin 3 | -0.0314133 |
| LOX | lysyl oxidase | -0.0312085 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.031169 |
| ENO1 | enolase 1, (alpha) | -0.0308326 |
| VCL | vinculin | -0.0306776 |
| DST | dystonin | -0.028521 |
| CDK6 | cyclin-dependent kinase 6 | -0.0277864 |
| HMGA2 | high mobility group AT-hook 2 | -0.0277202 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0277121 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0271271 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.02625 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0256728 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0250122 |
| CLIC4 | chloride intracellular channel 4 | -0.0249994 |
| PRSS23 | protease, serine, 23 | -0.02463 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0236429 |
| COL5A2 | collagen, type V, alpha 2 | -0.0236152 |
| ETV6 | ets variant 6 | -0.0229878 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0228579 |
| MAP4 | microtubule-associated protein 4 | -0.0227845 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0225888 |
| CUX1 | cut-like homeobox 1 | -0.022297 |
| AHR | aryl hydrocarbon receptor | -0.0222836 |
| SEPTIN7 | septin 7 | -0.0222625 |
| ASPH | aspartate beta-hydroxylase | -0.0220915 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0211057 |
| FN1 | fibronectin 1 | -0.0207466 |
| SBF2 | SET binding factor 2 | -0.0204575 |
| RAD51B | RAD51 paralog B | -0.0202629 |
| CENPF | centromere protein F, 350/400kDa | -0.0200677 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0197816 |
| RASAL2 | RAS protein activator like 2 | -0.0197809 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0189953 |
| JMJD1C | jumonji domain containing 1C | -0.0186297 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0184698 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0184629 |
| CENPE | centromere protein E, 312kDa | -0.018324 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0182347 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0181816 |
| RAI14 | retinoic acid induced 14 | -0.0179443 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0178088 |
| TUBA1B | tubulin, alpha 1b | -0.0177223 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0176394 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0175032 |
| MMP12 | matrix metallopeptidase 12 | -0.0173984 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0171384 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0171279 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0170335 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0169388 |
| DIAPH3 | diaphanous-related formin 3 | -0.0169156 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.016884 |
| EVI5 | ecotropic viral integration site 5 | -0.0167541 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0167194 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0165382 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0164872 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.016411 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0163103 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0161968 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0159497 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0159188 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0157074 |
| TMEM167A | transmembrane protein 167A | -0.0156398 |
| AAK1 | AP2 associated kinase 1 | -0.0155382 |
| NF1 | neurofibromin 1 | -0.01549 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0153686 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0152998 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0152037 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0152035 |
| TENM3 | teneurin transmembrane protein 3 | -0.015068 |
| RPS23 | ribosomal protein S23 | -0.0149023 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0147671 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0147608 |
| ERBIN | erbb2 interacting protein | -0.0146767 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0146463 |
| RPS6 | ribosomal protein S6 | -0.0146211 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0145336 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0144879 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0144095 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.014373 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0143231 |
| LIMA1 | LIM domain and actin binding 1 | -0.0142677 |
| FBN1 | fibrillin 1 | -0.0142631 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0141653 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | -0.0141578 |
