| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | IQ 1 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the IQ 1_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.418223 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.300947 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.161941 |
| NRG1 | neuregulin 1 | 0.138625 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.131031 |
| HLA-B | major histocompatibility complex, class I, B | 0.114989 |
| ASPH | aspartate beta-hydroxylase | 0.0994078 |
| HMGA2 | high mobility group AT-hook 2 | 0.0959966 |
| STC2 | stanniocalcin 2 | 0.0800432 |
| SFTPA2 | surfactant protein A2 | 0.0752313 |
| CALR | calreticulin | 0.0722102 |
| B2M | beta-2-microglobulin | 0.068508 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.067179 |
| ACTG1 | actin gamma 1 | 0.0629832 |
| TMSB4X | thymosin beta 4, X-linked | 0.062926 |
| TMSB10 | thymosin beta 10 | 0.0607688 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0578699 |
| VEGFA | vascular endothelial growth factor A | 0.0577084 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0567203 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.055659 |
| FTL | ferritin, light polypeptide | 0.0539944 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0538202 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0535569 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0523881 |
| LOXL2 | lysyl oxidase-like 2 | 0.0491962 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0488061 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0473498 |
| INTS6 | integrator complex subunit 6 | 0.0473352 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0448048 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.044129 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0438902 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0431194 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0414494 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0409822 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0407684 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0402734 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0398206 |
| LMNA | lamin A/C | 0.0395402 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0390105 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0386916 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0376745 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0376126 |
| MCL1 | myeloid cell leukemia 1 | 0.0371206 |
| PTMA | prothymosin, alpha | 0.0370394 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0364699 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0362226 |
| HLA-A | major histocompatibility complex, class I, A | 0.0356503 |
| EFNA5 | ephrin-A5 | 0.0350423 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0349962 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.033905 |
| CTSB | cathepsin B | 0.0334949 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0329139 |
| RNF213 | ring finger protein 213 | 0.0328849 |
| FLNA | filamin A, alpha | 0.0327231 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0324555 |
| ENO1 | enolase 1, (alpha) | 0.0321284 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0306776 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0304599 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0301114 |
| PALLD | palladin, cytoskeletal associated protein | 0.0294831 |
| SMAD3 | SMAD family member 3 | 0.0292357 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0287368 |
| S100A10 | S100 calcium binding protein A10 | 0.0285998 |
| DUSP6 | dual specificity phosphatase 6 | 0.0284054 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0281373 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0279245 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0278743 |
| GLIS3 | GLIS family zinc finger 3 | 0.02724 |
| MT2A | metallothionein 2A | 0.0269523 |
| ITGA1 | integrin, alpha 1 | 0.0266463 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0263807 |
| RASAL2 | RAS protein activator like 2 | 0.0261109 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0260085 |
| TGFB1 | transforming growth factor, beta 1 | 0.0259608 |
| NTN4 | netrin 4 | 0.0255513 |
| MLPH | melanophilin | 0.0252035 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0250603 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0250103 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0248787 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0245718 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0244661 |
| CTBP2 | C-terminal binding protein 2 | 0.0241638 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0241379 |
| SEPTIN9 | septin 9 | 0.0240615 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.023729 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0236807 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0235124 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.023379 |
| RPL31 | ribosomal protein L31 | 0.0231929 |
| TCIM | transcriptional and immune response regulator | 0.0227726 |
| EGFR | epidermal growth factor receptor | 0.0227244 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0226302 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0226144 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0223409 |
| FHL2 | four and a half LIM domains 2 | 0.0222953 |
| AEBP2 | AE binding protein 2 | 0.0220724 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0219038 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0216052 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0213494 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0212437 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.134967 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0984169 |
| CENPF | centromere protein F, 350/400kDa | -0.0618664 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0606515 |
| ZNF292 | zinc finger protein 292 | -0.0592187 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0581981 |
| AHR | aryl hydrocarbon receptor | -0.0580491 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0533939 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0509772 |
| OGA | O-GlcNAcase | -0.0488849 |
| NEK7 | NIMA-related kinase 7 | -0.0468267 |
| CANX | calnexin | -0.0463421 |
| RNF145 | ring finger protein 145 | -0.0444721 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0437145 |
| RBM39 | RNA binding motif protein 39 | -0.0427597 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0425293 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0403834 |
| ETNK1 | ethanolamine kinase 1 | -0.0401287 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0380776 |
| GOLGA4 | golgin A4 | -0.0368638 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0364941 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0362876 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0361891 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.034942 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0347379 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0347185 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0338768 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0338699 |
| ANLN | anillin, actin binding protein | -0.0329939 |
| SPAG9 | sperm associated antigen 9 | -0.0320792 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0316076 |
| XPO1 | exportin 1 | -0.0315983 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0313457 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0311909 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0309038 |
| JMJD1C | jumonji domain containing 1C | -0.03079 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0306895 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0305871 |
| TFG | TRK-fused gene | -0.0305022 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0297923 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0294804 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0287397 |
| NUP58 | nucleoporin 58 | -0.0286264 |
| SUCO | SUN domain containing ossification factor | -0.0282716 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0281056 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0281 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0278841 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0277956 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0276045 |
| GOLT1B | golgi transport 1B | -0.0276011 |
| SEPTIN7 | septin 7 | -0.0275269 |
| HELZ | helicase with zinc finger | -0.0274779 |
| CDC73 | cell division cycle 73 | -0.0268281 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0266827 |
| CD109 | CD109 molecule | -0.0264185 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0261238 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0260243 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0259666 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0259257 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0258295 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0257825 |
| RPS6 | ribosomal protein S6 | -0.0256579 |
| YME1L1 | YME1-like 1 ATPase | -0.0254951 |
| RTN4 | reticulon 4 | -0.0249228 |
| FNBP1 | formin binding protein 1 | -0.0247783 |
| RLF | rearranged L-myc fusion | -0.0244676 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0243075 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.02416 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0239595 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0239315 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0237995 |
| SRPK2 | SRSF protein kinase 2 | -0.0236487 |
| FAM168B | family with sequence similarity 168, member B | -0.0235999 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0233233 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0233131 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.023259 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0230974 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0230579 |
| MKI67 | marker of proliferation Ki-67 | -0.0226911 |
| RO60 | Ro60, Y RNA binding protein | -0.0224512 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0222856 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0221933 |
| TPX2 | TPX2, microtubule-associated | -0.0221041 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0219742 |
| USP12 | ubiquitin specific peptidase 12 | -0.0218793 |
| USP3 | ubiquitin specific peptidase 3 | -0.0217997 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0216934 |
| COG5 | component of oligomeric golgi complex 5 | -0.0216772 |
| CEP350 | centrosomal protein 350kDa | -0.021454 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0214404 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0214153 |
| SP3 | Sp3 transcription factor | -0.0213434 |
| RPS2 | ribosomal protein S2 | -0.0213381 |
| MATR3 | matrin 3 | -0.0212296 |
| RAB18 | RAB18, member RAS oncogene family | -0.0212062 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0209282 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0206483 |
| DIAPH3 | diaphanous-related formin 3 | -0.0206132 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0205141 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0203582 |
