IRAK1 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description interleukin-1 receptor-associated kinase 1|This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3654)
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Genes

100 substrates of the kinase IRAK1 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
HIRIP3 HIRA interacting protein 3
REPS1 RALBP1 associated Eps domain containing 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
LMO7 LIM domain 7
AGTPBP1 ATP/GTP binding protein 1
ACVR1B activin A receptor, type IB
ELMO2 engulfment and cell motility 2
LYST lysosomal trafficking regulator
SON SON DNA binding protein
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
PLIN5 perilipin 5
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
TTN titin
KMT2C lysine (K)-specific methyltransferase 2C
LUZP1 leucine zipper protein 1
DPYSL2 dihydropyrimidinase-like 2
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
STX8 syntaxin 8
SGOL2 shugoshin-like 2 (S. pombe)
TGFBR1 transforming growth factor, beta receptor 1
SH3RF3 SH3 domain containing ring finger 3
ZNF618 zinc finger protein 618
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
KALRN kalirin, RhoGEF kinase
EXPH5 exophilin 5
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ARHGAP15 Rho GTPase activating protein 15
TUBA4A tubulin, alpha 4a
CCND1 cyclin D1
RPS7 ribosomal protein S7
SF3B1 splicing factor 3b, subunit 1, 155kDa
RIC1 RAB6A GEF complex partner 1
PLN phospholamban
UBE4B ubiquitination factor E4B
DNMBP dynamin binding protein
GPATCH8 G patch domain containing 8
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
TERF2IP telomeric repeat binding factor 2, interacting protein
FGD5 FYVE, RhoGEF and PH domain containing 5
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
YES1 YES proto-oncogene 1, Src family tyrosine kinase
CLTA clathrin, light chain A
EEF2 eukaryotic translation elongation factor 2
GPR161 G protein-coupled receptor 161
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
FYN FYN proto-oncogene, Src family tyrosine kinase
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
PHIP pleckstrin homology domain interacting protein
SORBS3 sorbin and SH3 domain containing 3
COPS5 COP9 signalosome subunit 5
DOCK2 dedicator of cytokinesis 2
CHERP calcium homeostasis endoplasmic reticulum protein
ZNF624 zinc finger protein 624
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
EPRS glutamyl-prolyl-tRNA synthetase
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
CASC5 cancer susceptibility candidate 5
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
MYBBP1A MYB binding protein (P160) 1a
ZAK sterile alpha motif and leucine zipper containing kinase AZK
FGR FGR proto-oncogene, Src family tyrosine kinase
RAN RAN, member RAS oncogene family
RPL18A ribosomal protein L18a
CNR1 cannabinoid receptor 1 (brain)
TUBA1C tubulin, alpha 1c
TUBA1B tubulin, alpha 1b
ANAPC1 anaphase promoting complex subunit 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
ZNF516 zinc finger protein 516
PLD2 phospholipase D2
TSLIG3A tRNA splicing ligase complex subunit 3A
FLNA filamin A, alpha
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
BIN2 bridging integrator 2
EIF3CL eukaryotic translation initiation factor 3, subunit C-like
UBR5 ubiquitin protein ligase E3 component n-recognin 5
GSTP1 glutathione S-transferase pi 1
FAM114A2 family with sequence similarity 114, member A2
NXF1 nuclear RNA export factor 1
KCNK18 potassium channel, two pore domain subfamily K, member 18
ZNF391 zinc finger protein 391
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
PRDX5 peroxiredoxin 5
NUP133 nucleoporin 133kDa
PPL periplakin
EIF3C eukaryotic translation initiation factor 3, subunit C
SLC14A2 solute carrier family 14 (urea transporter), member 2
TUBA8 tubulin, alpha 8
ZC3H13 zinc finger CCCH-type containing 13
SBDS Shwachman-Bodian-Diamond syndrome
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
TFIP11 tuftelin interacting protein 11
SEC11C SEC11 homolog C (S. cerevisiae)
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
BLVRA biliverdin reductase A
TSC2 tuberous sclerosis 2