IRAK1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description interleukin-1 receptor-associated kinase 1|This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3654)
External Link https://ncbi.nlm.nih.gov/gene/3654
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Genes

498 genes differentially expressed following the IRAK1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
AQP3 aquaporin 3 (Gill blood group) 0.0124211
RAI14 retinoic acid induced 14 0.0112739
LGALS13 lectin, galactoside-binding, soluble, 13 0.0111742
CCN2 cellular communication network factor 2 0.0109441
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0107214
XPO7 exportin 7 0.0107015
ACTA2 actin, alpha 2, smooth muscle, aorta 0.0106243
MUC16 mucin 16, cell surface associated 0.010395
INAVA innate immunity activator 0.0103929
IFI44L interferon-induced protein 44-like 0.0102921
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.0102433
IFI44 interferon-induced protein 44 0.0101751
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.0101295
COG7 component of oligomeric golgi complex 7 0.0100622
ACP5 acid phosphatase 5, tartrate resistant 0.010022
CD58 CD58 molecule 0.0100126
ITM2C integral membrane protein 2C 0.00972448
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00970829
STK10 serine/threonine kinase 10 0.00957507
PSCA prostate stem cell antigen 0.0094653
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00940858
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00909029
SDC1 syndecan 1 0.00906023
TAPBP TAP binding protein (tapasin) 0.00877775
THBS2 thrombospondin 2 0.00876885
CXCL12 chemokine (C-X-C motif) ligand 12 0.00875104
S100P S100 calcium binding protein P 0.00872423
ISG15 ISG15 ubiquitin-like modifier 0.00871726
LAMP3 lysosomal-associated membrane protein 3 0.00866613
FCGBP Fc fragment of IgG binding protein 0.0086612
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00854694
CEMIP cell migration inducing protein, hyaluronan binding 0.00853382
ATF3 activating transcription factor 3 0.00851155
TUBB2A tubulin, beta 2A class IIa 0.00844683
MAL mal, T-cell differentiation protein 0.00842763
SNAI2 snail family zinc finger 2 0.008409
MAGEA3 melanoma antigen family A3 0.00838375
AKR1C3 aldo-keto reductase family 1, member C3 0.0083662
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00835677
IFI16 interferon, gamma-inducible protein 16 0.0083107
CLDN10 claudin 10 0.00829298
LPAR6 lysophosphatidic acid receptor 6 0.00827591
A2M alpha-2-macroglobulin 0.00819003
TRIM29 tripartite motif containing 29 0.00810395
CYBA cytochrome b-245, alpha polypeptide 0.00806673
ASS1 argininosuccinate synthase 1 0.008054
FABP7 fatty acid binding protein 7, brain 0.00800718
MSMB microseminoprotein, beta- 0.00796726
BGN biglycan 0.00795017
LHFP lipoma HMGIC fusion partner 0.00791489
IVNS1ABP influenza virus NS1A binding protein 0.00790706
WFDC1 WAP four-disulfide core domain 1 0.00787744
TIMP3 TIMP metallopeptidase inhibitor 3 0.00786174
GMDS GDP-mannose 4,6-dehydratase 0.00780477
TBX2 T-box 2 0.00777827
LGALS9 lectin, galactoside-binding, soluble, 9 0.00777771
PODXL podocalyxin-like 0.00776369
TADA2A transcriptional adaptor 2A 0.00774662
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.00763115
GYPC glycophorin C (Gerbich blood group) 0.00761621
TRIB2 tribbles pseudokinase 2 0.00761251
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.00758349
COL9A3 collagen, type IX, alpha 3 0.00753332
MSLN mesothelin 0.00750935
CLEC2B C-type lectin domain family 2, member B 0.00748305
VDAC1 voltage-dependent anion channel 1 0.00743804
ADD3 adducin 3 (gamma) 0.00743305
KRT5 keratin 5, type II 0.0074081
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00739238
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0073828
IFITM1 interferon induced transmembrane protein 1 0.00735226
TSPAN4 tetraspanin 4 0.00733671
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00732279
FGFR3 fibroblast growth factor receptor 3 0.00727386
KRT13 keratin 13, type I 0.00722425
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00718804
DUSP22 dual specificity phosphatase 22 0.00716931
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00714949
BHLHE41 basic helix-loop-helix family, member e41 0.00709953
BAG3 BCL2-associated athanogene 3 0.00709535
IL7R interleukin 7 receptor 0.00701925
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00700311
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00699978
C10ORF10 chromosome 10 open reading frame 10 0.00699487
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00699372
AEBP1 AE binding protein 1 0.00698895
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00698425
MLF1 myeloid leukemia factor 1 0.00696701
COPS7A COP9 signalosome subunit 7A 0.00695995
PRNP prion protein 0.00695816
LYPD1 LY6/PLAUR domain containing 1 0.00695525
IL10RB interleukin 10 receptor, beta 0.00689011
BATF3 basic leucine zipper transcription factor, ATF-like 3 0.00684589
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00682959
NPY1R neuropeptide Y receptor Y1 0.00681489
LY6E lymphocyte antigen 6 complex, locus E 0.00678591
MIA melanoma inhibitory activity 0.0067662
ISYNA1 inositol-3-phosphate synthase 1 0.00674915
MAGEA12 melanoma antigen family A12 0.00674343
FOXC1 forkhead box C1 0.0067402
TARBP1 TAR (HIV-1) RNA binding protein 1 0.0067361
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.0067288
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.00670656
DNASE1L3 deoxyribonuclease I-like 3 0.00667151
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00667092
IL13RA2 interleukin 13 receptor, alpha 2 0.00666991
CD59 CD59 molecule, complement regulatory protein 0.0066534
KRT15 keratin 15, type I 0.00663382
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.00663332
BAMBI BMP and activin membrane-bound inhibitor 0.00661051
CD48 CD48 molecule 0.00659822
CHEK1 checkpoint kinase 1 0.00658139
NUAK1 NUAK family, SNF1-like kinase, 1 0.00657921
PIPOX pipecolic acid oxidase 0.0065628
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00655644
FMO2 flavin containing monooxygenase 2 (non-functional) 0.0065472
TBC1D31 TBC1 domain family, member 31 0.00654241
RABGAP1 RAB GTPase activating protein 1 0.00653481
THY1 Thy-1 cell surface antigen 0.00652334
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00651682
SUMO3 small ubiquitin-like modifier 3 0.0065005
FMO1 flavin containing monooxygenase 1 0.006489
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00648792
QPRT quinolinate phosphoribosyltransferase 0.00648115
COL11A1 collagen, type XI, alpha 1 0.00647632
FABP4 fatty acid binding protein 4, adipocyte 0.00647306
FSCN1 fascin actin-bundling protein 1 0.00644642
IL2RG interleukin 2 receptor, gamma 0.00640792
CPVL carboxypeptidase, vitellogenic-like 0.00640372
CCDC85B coiled-coil domain containing 85B 0.00639442
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00638851
DMTF1 cyclin D binding myb-like transcription factor 1 0.00638682
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00638581
CD300A CD300a molecule 0.00638231
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00637255
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.0063675
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00634896
ITGB4 integrin, beta 4 0.0063429
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.00632019
S100A8 S100 calcium binding protein A8 0.00629854
CREBL2 cAMP responsive element binding protein-like 2 0.00629767
PLAT plasminogen activator, tissue 0.0062303
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00621379
COL2A1 collagen, type II, alpha 1 0.00620279
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00617861
MGP matrix Gla protein 0.00617427
NCK1 NCK adaptor protein 1 0.00616928
THBS1 thrombospondin 1 0.00616449
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.00615169
POPDC3 popeye domain containing 3 0.00613501
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 0.0060532
IL6R interleukin 6 receptor 0.00604731
CFI complement factor I 0.00603698
KAZN kazrin, periplakin interacting protein 0.00601458
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00601407
CLN5 ceroid-lipofuscinosis, neuronal 5 0.00601399
AKIRIN1 akirin 1 0.00600286
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00598979
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00597381
RGS10 regulator of G-protein signaling 10 0.00597173
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.00591227
GTPBP8 GTP-binding protein 8 (putative) 0.00590493
KRT17 keratin 17, type I 0.00586151
RRAD Ras-related associated with diabetes 0.00585544
KYNU kynureninase 0.00585117
ARHGAP15 Rho GTPase activating protein 15 0.00584498
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.00584366
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 0.00582967
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00581737
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00580828
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00580809
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00580731
SUGCT succinyl-CoA:glutarate-CoA transferase 0.00580477
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00580475
MYH10 myosin, heavy chain 10, non-muscle 0.00577989
TMEM160 transmembrane protein 160 0.00577858
C7 complement component 7 0.00577134
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.00576687
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00576235
LY96 lymphocyte antigen 96 0.00575858
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.0057577
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 0.00575005
CCL5 chemokine (C-C motif) ligand 5 0.005747
HIST1H2AC histone cluster 1, H2ac 0.00573661
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.00571945
SMYD2 SET and MYND domain containing 2 0.00570707
AKR1C2 aldo-keto reductase family 1, member C2 0.005702
RTP4 receptor (chemosensory) transporter protein 4 0.00569547
FAM162A family with sequence similarity 162, member A 0.00565639
CETN2 centrin, EF-hand protein, 2 0.00565603
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00565277
MCOLN1 mucolipin 1 0.00564933
ATF5 activating transcription factor 5 0.00564632
KIAA0100 KIAA0100 0.00564174
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00563501
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00563495
MMP10 matrix metallopeptidase 10 0.0056274
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.0056257
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.0056055
BTN3A3 butyrophilin, subfamily 3, member A3 0.00559548
LAMB1 laminin, beta 1 0.00557658
HDAC9 histone deacetylase 9 0.00557524
KLF2 Kruppel-like factor 2 0.0055732
TSPAN1 tetraspanin 1 0.0055657
BAX BCL2-associated X protein 0.00552388
TPM4 tropomyosin 4 0.00552112
GAS6 growth arrest-specific 6 0.00551614
HMGA1 high mobility group AT-hook 1 0.00549864
KDM5D lysine (K)-specific demethylase 5D 0.00549507
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.00547144
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00546582
DOK5 docking protein 5 0.0054622
EPS8L2 EPS8-like 2 0.00545108
AHCY adenosylhomocysteinase 0.00544641
SH2B3 SH2B adaptor protein 3 0.00542494
DCN decorin 0.0054122
NMRK1 nicotinamide riboside kinase 1 0.005409
MREG melanoregulin 0.00540111
TSPAN8 tetraspanin 8 0.00537386
FERMT1 fermitin family member 1 0.0053625
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00535791
AK4 adenylate kinase 4 0.0053438
PLS3 plastin 3 0.00533653
ANTXR1 anthrax toxin receptor 1 0.00530454
MAST4 microtubule associated serine/threonine kinase family member 4 0.00529401
FBLN5 fibulin 5 0.00529007
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.0052878
LDB2 LIM domain binding 2 0.00528618
VLDLR very low density lipoprotein receptor 0.00528296
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00528214
KRT6A keratin 6A, type II 0.00526998
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00525799
ADAM28 ADAM metallopeptidase domain 28 0.00524942
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00524571
DENND2B DENN domain containing 2B 0.0052335
PIR pirin (iron-binding nuclear protein) 0.00520503
RRBP1 ribosome binding protein 1 0.00520455
COMP cartilage oligomeric matrix protein 0.00519759
IQCG IQ motif containing G 0.00519591
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00517774
BTN3A2 butyrophilin, subfamily 3, member A2 0.00517664
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0051745
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00516166
PRELP proline/arginine-rich end leucine-rich repeat protein 0.00516103
FRZB frizzled-related protein 0.00514882
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00514429
TRIM14 tripartite motif containing 14 0.00514287
SRPX sushi-repeat containing protein, X-linked 0.00513894
ITM2A integral membrane protein 2A 0.00512569

decreased expression

Symbol Name Standardized Value
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0137827
H1-0 H1.0 linker histone -0.0125001
ELANE elastase, neutrophil expressed -0.0118052
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.0111221
CTSG cathepsin G -0.0108732
SLC38A1 solute carrier family 38, member 1 -0.0106156
XIC X chromosome inactivation center -0.00996
MT1M metallothionein 1M -0.00995114
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00988549
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00972699
TPSAB1 tryptase alpha/beta 1 -0.00928131
GOLM1 golgi membrane protein 1 -0.00909923
ARID4B AT rich interactive domain 4B (RBP1-like) -0.00903967
STC2 stanniocalcin 2 -0.00890021
AREG amphiregulin -0.00889322
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00884691
SCG5 secretogranin V -0.00853463
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00846566
AZU1 azurocidin 1 -0.00842655
AGR2 anterior gradient 2 -0.00836996
ANKRD10 ankyrin repeat domain 10 -0.00826043
SCGB1D2 secretoglobin, family 1D, member 2 -0.00812549
NIT1 nitrilase 1 -0.00805861
PTPRE protein tyrosine phosphatase, receptor type, E -0.00802923
PON3 paraoxonase 3 -0.00802852
ANXA3 annexin A3 -0.0079095
NAV2 neuron navigator 2 -0.0078446
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00784326
SCARB2 scavenger receptor class B, member 2 -0.0078139
STK39 serine threonine kinase 39 -0.00777035
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00775806
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.00775804
SOX11 SRY (sex determining region Y)-box 11 -0.00768905
TRIO trio Rho guanine nucleotide exchange factor -0.00762679
DOCK9 dedicator of cytokinesis 9 -0.0075418
ALOX5 arachidonate 5-lipoxygenase -0.00752728
ZEB1 zinc finger E-box binding homeobox 1 -0.00750635
SYBU syntabulin (syntaxin-interacting) -0.00738419
PHACTR2 phosphatase and actin regulator 2 -0.0073573
FOXO1 forkhead box O1 -0.00733348
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00729032
WASHC4 WASH complex subunit 4 -0.00728375
USP6NL USP6 N-terminal like -0.00719158
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0071901
DCLK1 doublecortin-like kinase 1 -0.00716499
GAB2 GRB2-associated binding protein 2 -0.00714351
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -0.00711002
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.0070335
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00702926
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00697467
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00695315
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00685661
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00673454
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.006643
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 -0.00661597
TRIB3 tribbles pseudokinase 3 -0.00661452
RGS13 regulator of G-protein signaling 13 -0.00661184
CHD7 chromodomain helicase DNA binding protein 7 -0.00658427
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.00654711
APOB apolipoprotein B -0.00653765
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00650604
WSB1 WD repeat and SOCS box containing 1 -0.00646972
LAMP2 lysosomal-associated membrane protein 2 -0.00644916
MTCL1 microtubule crosslinking factor 1 -0.00643808
IRS2 insulin receptor substrate 2 -0.00640219
HAND2-AS1 HAND2 antisense RNA 1 (head to head) -0.00639628
SCGB2A2 secretoglobin, family 2A, member 2 -0.00638182
LYST lysosomal trafficking regulator -0.00636553
ABAT 4-aminobutyrate aminotransferase -0.00636281
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.0063263
INHBB inhibin, beta B -0.00628701
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.0062653
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00626492
KIF5B kinesin family member 5B -0.00625086
MT1E metallothionein 1E -0.00624771
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -0.00624524
CDC45 cell division cycle 45 -0.00623638
TLE4 transducin-like enhancer of split 4 -0.00622085
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.00617896
ANO1 anoctamin 1, calcium activated chloride channel -0.00617195
TASOR2 transcription activation suppressor family member 2 -0.0060912
AKAP8 A kinase (PRKA) anchor protein 8 -0.00608197
HOXB6 homeobox B6 -0.00606046
ECHDC3 enoyl CoA hydratase domain containing 3 -0.00605478
GARS1 glycyl-tRNA synthetase 1 -0.00602628
IL1R1 interleukin 1 receptor, type I -0.006026
PFKP phosphofructokinase, platelet -0.00599851
RANBP1 RAN binding protein 1 -0.00598542
TCF4 transcription factor 4 -0.00598078
MBNL2 muscleblind-like splicing regulator 2 -0.00596944
JMJD1C jumonji domain containing 1C -0.00596922
IDE insulin-degrading enzyme -0.00596406
CLC Charcot-Leyden crystal galectin -0.00594265
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00592946
BASP1 brain abundant, membrane attached signal protein 1 -0.00591016
SAP30 Sin3A-associated protein, 30kDa -0.00591008
ERBIN erbb2 interacting protein -0.00589307
HBD hemoglobin, delta -0.00587057
PCP4 Purkinje cell protein 4 -0.00586179
STMN2 stathmin 2 -0.00585072
S100A12 S100 calcium binding protein A12 -0.00584833
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -0.00584743
BCL6 B-cell CLL/lymphoma 6 -0.00583765
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00583047
ZNF43 zinc finger protein 43 -0.00580111
CD9 CD9 molecule -0.00578696
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00578326
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) -0.00578261
AHCYL1 adenosylhomocysteinase-like 1 -0.0057817
TOP2B topoisomerase (DNA) II beta 180kDa -0.00576942
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.00576206
RUFY3 RUN and FYVE domain containing 3 -0.00576062
CREG1 cellular repressor of E1A-stimulated genes 1 -0.00574385
EREG epiregulin -0.00571076
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -0.00569491
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00569138
DENND5A DENN/MADD domain containing 5A -0.00568194
STK26 serine/threonine protein kinase 26 -0.00567199
RTN3 reticulon 3 -0.00566884
KDM6A lysine (K)-specific demethylase 6A -0.00562887
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00561591
UXT ubiquitously-expressed, prefoldin-like chaperone -0.00561526
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00561031
SC5D sterol-C5-desaturase -0.00560262
ABHD3 abhydrolase domain containing 3 -0.00559773
PENK proenkephalin -0.00559303
DNMBP dynamin binding protein -0.00559102
ADGRL3 adhesion G protein-coupled receptor L3 -0.00558258
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0055746
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00555633
CTNND2 catenin (cadherin-associated protein), delta 2 -0.00555344
CDC20 cell division cycle 20 -0.00552766
WDFY3 WD repeat and FYVE domain containing 3 -0.00552739
MID1IP1 MID1 interacting protein 1 -0.0055238
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -0.00551174
FEM1C fem-1 homolog c (C. elegans) -0.00550843
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -0.00550702
ADIPOR2 adiponectin receptor 2 -0.00549411
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -0.00549156
NPTN neuroplastin -0.00547376
NOVA1 neuro-oncological ventral antigen 1 -0.00545519
NCAM1 neural cell adhesion molecule 1 -0.0054335
MOCOS molybdenum cofactor sulfurase -0.00542687
CSRP1 cysteine and glycine-rich protein 1 -0.00542222
DPF2 D4, zinc and double PHD fingers family 2 -0.00540258
TMSB15A thymosin beta 15a -0.00539494
HMGB2 high mobility group box 2 -0.00539033
ELF1 E74-like factor 1 (ets domain transcription factor) -0.00537029
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.00535523
DGKD diacylglycerol kinase, delta 130kDa -0.00535503
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -0.00535326
NBPF10 neuroblastoma breakpoint family, member 10 -0.00534581
ZBTB20 zinc finger and BTB domain containing 20 -0.00533606
ARGLU1 arginine and glutamate rich 1 -0.00532679
CDA cytidine deaminase -0.00532519
HOXB5 homeobox B5 -0.00532461
REV1 REV1, polymerase (DNA directed) -0.00531949
HEPH hephaestin -0.00530613
PRTN3 proteinase 3 -0.00530449
FASTKD3 FAST kinase domains 3 -0.0052996
ARHGAP44 Rho GTPase activating protein 44 -0.00529228
TENT4A terminal nucleotidyltransferase 4A -0.0052916
LPAR1 lysophosphatidic acid receptor 1 -0.00528115
NMT2 N-myristoyltransferase 2 -0.00527143
SFTPB surfactant protein B -0.00526028
SYT1 synaptotagmin I -0.00525826
ANKRD12 ankyrin repeat domain 12 -0.0052568
CPE carboxypeptidase E -0.0052534
TBL1X transducin (beta)-like 1X-linked -0.00525078
ESYT1 extended synaptotagmin-like protein 1 -0.00524239
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00523187
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00523183
MAPK6 mitogen-activated protein kinase 6 -0.00521992
BPI bactericidal/permeability-increasing protein -0.00521774
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00520844
ELOVL5 ELOVL fatty acid elongase 5 -0.00518163
NR5A2 nuclear receptor subfamily 5, group A, member 2 -0.00517279
HDAC4 histone deacetylase 4 -0.00517058
GAL galanin/GMAP prepropeptide -0.00517015
EXPH5 exophilin 5 -0.00516376
MT1F metallothionein 1F -0.00516119
FMO5 flavin containing monooxygenase 5 -0.00516038
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.0051191
CHN1 chimerin 1 -0.00510507
ASPH aspartate beta-hydroxylase -0.00509587
PRC1 protein regulator of cytokinesis 1 -0.00509552
RGCC regulator of cell cycle -0.00507971
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00507079
BTG2 BTG family, member 2 -0.00506306
FGG fibrinogen gamma chain -0.00504677
TNC tenascin C -0.00502907
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00502262
ACLY ATP citrate lyase -0.00501949
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00501754
NMU neuromedin U -0.00501632
RUFY1 RUN and FYVE domain containing 1 -0.00501506
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.00501506
GCA grancalcin, EF-hand calcium binding protein -0.0050131
RNF6 ring finger protein (C3H2C3 type) 6 -0.00500807
CERS4 ceramide synthase 4 -0.00499795
TFF3 trefoil factor 3 (intestinal) -0.00499113
CLEC5A C-type lectin domain family 5, member A -0.00498955
CLDN1 claudin 1 -0.00498542
SLBP stem-loop binding protein -0.00498356
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 -0.00497638
MAP7 microtubule-associated protein 7 -0.00497259
ANK2 ankyrin 2, neuronal -0.00497003
ZBTB16 zinc finger and BTB domain containing 16 -0.00496571
MAPK1 mitogen-activated protein kinase 1 -0.00494583
EPN2 epsin 2 -0.00494143
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.0049401
CXCR5 chemokine (C-X-C motif) receptor 5 -0.00490659
CENPE centromere protein E, 312kDa -0.00490026
CTSH cathepsin H -0.0048942
TOX3 TOX high mobility group box family member 3 -0.004894
ZFR zinc finger RNA binding protein -0.00488484
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A -0.00488235
MCL1 myeloid cell leukemia 1 -0.00487894
SEPTIN8 septin 8 -0.00487851
FRY furry homolog (Drosophila) -0.00486929
PAWR PRKC, apoptosis, WT1, regulator -0.00485839
MALL mal, T-cell differentiation protein-like -0.00485807
ARG1 arginase 1 -0.00484802
DSC1 desmocollin 1 -0.00484566
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -0.00483172
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00482819
LAMA3 laminin, alpha 3 -0.00482515
TPD52L1 tumor protein D52-like 1 -0.00481213
CCNG2 cyclin G2 -0.00480046
FNDC3A fibronectin type III domain containing 3A -0.00479437
ADAM9 ADAM metallopeptidase domain 9 -0.00479079
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00477955
TOB2 transducer of ERBB2, 2 -0.00477849
NOTCH2 notch 2 -0.00476982
PFDN4 prefoldin subunit 4 -0.00475923
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00475827
ATP9A ATPase, class II, type 9A -0.00475807
NUMA1 nuclear mitotic apparatus protein 1 -0.00475647
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide -0.0047474
ZBTB18 zinc finger and BTB domain containing 18 -0.0047462
TSC22D1 TSC22 domain family, member 1 -0.00474527
IFT57 intraflagellar transport 57 -0.00474512
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -0.00472326
CCDC92 coiled-coil domain containing 92 -0.0047218
ESR1 estrogen receptor 1 -0.00472022
QPCT glutaminyl-peptide cyclotransferase -0.00471483
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00469884
STX4 syntaxin 4 -0.00469469
UGDH UDP-glucose 6-dehydrogenase -0.00469079