IRAK1 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description interleukin-1 receptor-associated kinase 1|This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3654)
External Link http://www.ncbi.nlm.nih.gov/gene/3654
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Genes

5 substrates of the kinase IRAK1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1
PELI1 pellino E3 ubiquitin protein ligase 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)