IRAK2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description interleukin-1 receptor-associated kinase 2|IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3656)
External Link https://ncbi.nlm.nih.gov/gene/3656
Similar Terms
Downloads & Tools

Genes

500 genes differentially expressed following the IRAK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CNN3 calponin 3, acidic 0.0151782
STK10 serine/threonine kinase 10 0.0142392
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.0121146
TSPYL5 TSPY-like 5 0.0117455
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0116769
RHOBTB3 Rho-related BTB domain containing 3 0.0116206
FABP4 fatty acid binding protein 4, adipocyte 0.0114577
CD36 CD36 molecule (thrombospondin receptor) 0.0112036
CRISP3 cysteine-rich secretory protein 3 0.0109417
COL3A1 collagen, type III, alpha 1 0.0107645
OLFM4 olfactomedin 4 0.0106818
GOLM1 golgi membrane protein 1 0.0106691
PLAT plasminogen activator, tissue 0.0104188
GREM1 gremlin 1, DAN family BMP antagonist 0.0103167
SYNM synemin, intermediate filament protein 0.010282
C1QA complement component 1, q subcomponent, A chain 0.0101948
CA2 carbonic anhydrase II 0.0101848
APOD apolipoprotein D 0.0101792
IRS2 insulin receptor substrate 2 0.0101217
DPYD dihydropyrimidine dehydrogenase 0.00974759
MEIS2 Meis homeobox 2 0.00971998
ZFPM2 zinc finger protein, FOG family member 2 0.00964004
SPARCL1 SPARC-like 1 (hevin) 0.00960501
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.00955507
CRABP2 cellular retinoic acid binding protein 2 0.00938038
GALC galactosylceramidase 0.00937161
SPRY2 sprouty homolog 2 (Drosophila) 0.00930539
WT1 Wilms tumor 1 0.009276
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00925065
MARCKS myristoylated alanine-rich protein kinase C substrate 0.0091971
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.00916606
PTGIS prostaglandin I2 (prostacyclin) synthase 0.00904741
SOX11 SRY (sex determining region Y)-box 11 0.0090189
CHD7 chromodomain helicase DNA binding protein 7 0.00901729
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00895564
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00894311
ZEB1 zinc finger E-box binding homeobox 1 0.00887129
PRKCA protein kinase C, alpha 0.00873677
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00866401
CANX calnexin 0.00862061
PDZD2 PDZ domain containing 2 0.00850559
DMXL2 Dmx-like 2 0.00850425
LAMA4 laminin, alpha 4 0.00835489
SUB1 SUB1 homolog (S. cerevisiae) 0.00831567
KCTD12 potassium channel tetramerization domain containing 12 0.00826439
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00826249
NNT nicotinamide nucleotide transhydrogenase 0.00825287
SPTBN1 spectrin, beta, non-erythrocytic 1 0.00824586
BEX1 brain expressed, X-linked 1 0.00818212
RGCC regulator of cell cycle 0.00812125
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00805205
ADGRL2 adhesion G protein-coupled receptor L2 0.00804901
ANXA3 annexin A3 0.00803871
CELF2 CUGBP, Elav-like family member 2 0.0080365
SORBS1 sorbin and SH3 domain containing 1 0.00802709
RTN1 reticulon 1 0.00798428
DLD dihydrolipoamide dehydrogenase 0.00791576
SVIL supervillin 0.00785222
C1QB complement component 1, q subcomponent, B chain 0.00783486
PRKCB protein kinase C, beta 0.00781553
GAS1 growth arrest-specific 1 0.00779057
NPM3 nucleophosmin/nucleoplasmin 3 0.00776131
NOVA1 neuro-oncological ventral antigen 1 0.00774151
FAR2 fatty acyl CoA reductase 2 0.00772781
NID1 nidogen 1 0.00769304
WLS wntless Wnt ligand secretion mediator 0.00767958
NOTCH2 notch 2 0.00760721
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00759415
GPM6B glycoprotein M6B 0.00756735
REEP1 receptor accessory protein 1 0.00751303
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.00748503
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00745764
PLP1 proteolipid protein 1 0.0074266
SCARB2 scavenger receptor class B, member 2 0.00741755
ANK2 ankyrin 2, neuronal 0.00739679
FHL1 four and a half LIM domains 1 0.00737105
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00737075
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.00734927
PNMA8A PNMA family member 8A 0.00733239
REG3A regenerating islet-derived 3 alpha 0.00731033
CD163 CD163 molecule 0.00730647
EHF ets homologous factor 0.00728527
NRIP1 nuclear receptor interacting protein 1 0.00727859
ITGA6 integrin, alpha 6 0.00726706
SRSF1 serine/arginine-rich splicing factor 1 0.00724837
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00717877
FBN1 fibrillin 1 0.00715059
PLAGL1 pleiomorphic adenoma gene-like 1 0.00711401
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00710092
ASPH aspartate beta-hydroxylase 0.00709504
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00709062
CCP110 centriolar coiled coil protein 110kDa 0.00707235
MGLL monoglyceride lipase 0.00701209
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.00699088
QKI QKI, KH domain containing, RNA binding 0.00698407
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00697572
WWTR1 WW domain containing transcription regulator 1 0.00694708
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00688007
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00687263
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0068701
PLXNC1 plexin C1 0.00684465
GBP1 guanylate binding protein 1, interferon-inducible 0.00684048
IFI44L interferon-induced protein 44-like 0.00683828
CTSK cathepsin K 0.00683126
PANK3 pantothenate kinase 3 0.0068058
NBPF10 neuroblastoma breakpoint family, member 10 0.00676873
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00676292
APLP2 amyloid beta (A4) precursor-like protein 2 0.00675308
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00673961
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00668833
RTN3 reticulon 3 0.00668001
FZD6 frizzled class receptor 6 0.00667793
PNMA1 paraneoplastic Ma antigen 1 0.00666296
RIN2 Ras and Rab interactor 2 0.00665709
PITX3 paired-like homeodomain 3 0.00663703
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00663212
STON1 stonin 1 0.00662213
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00660779
CALD1 caldesmon 1 0.00657753
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.00657238
PDZRN3 PDZ domain containing ring finger 3 0.00656548
NIPSNAP2 nipsnap homolog 2 0.00656504
TFRC transferrin receptor 0.00655819
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 0.0065512
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00654814
TMED5 transmembrane emp24 protein transport domain containing 5 0.00653096
ZMYND11 zinc finger, MYND-type containing 11 0.00650292
CEP170 centrosomal protein 170kDa 0.0064995
EREG epiregulin 0.006489
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.00648239
TLE4 transducin-like enhancer of split 4 0.00647003
FNBP1 formin binding protein 1 0.00644847
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.00644811
RTN2 reticulon 2 0.00642749
C2CD5 C2 calcium-dependent domain containing 5 0.00642123
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00641474
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.00640206
PXDN peroxidasin 0.00639214
ATP11B ATPase, class VI, type 11B 0.00635257
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.0063325
SUCO SUN domain containing ossification factor 0.00632932
MNDA myeloid cell nuclear differentiation antigen 0.0063263
CYBB cytochrome b-245, beta polypeptide 0.00632495
AHCYL1 adenosylhomocysteinase-like 1 0.00631858
SPON1 spondin 1, extracellular matrix protein 0.00631255
HNMT histamine N-methyltransferase 0.00629053
ZBTB18 zinc finger and BTB domain containing 18 0.00627606
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.00627507
NID2 nidogen 2 (osteonidogen) 0.00627086
CD93 CD93 molecule 0.00626201
THBS1 thrombospondin 1 0.00625952
USP6NL USP6 N-terminal like 0.00625408
CFD complement factor D (adipsin) 0.00625336
RRM2 ribonucleotide reductase M2 0.00624927
COL1A2 collagen, type I, alpha 2 0.00623187
KCTD3 potassium channel tetramerization domain containing 3 0.00622893
PDLIM3 PDZ and LIM domain 3 0.00622862
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00622546
MAPK1 mitogen-activated protein kinase 1 0.00620864
GATA6 GATA binding protein 6 0.00620711
ADD3 adducin 3 (gamma) 0.00620223
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00617976
FCGBP Fc fragment of IgG binding protein 0.00616236
KRT23 keratin 23, type I 0.00615838
PMP22 peripheral myelin protein 22 0.00614745
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00613576
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.00611729
AGR2 anterior gradient 2 0.00611545
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.00611137
MEOX2 mesenchyme homeobox 2 0.00609846
CADPS2 Ca++-dependent secretion activator 2 0.00608458
PCP4 Purkinje cell protein 4 0.00607932
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.00607544
PDGFD platelet derived growth factor D 0.006075
PSIP1 PC4 and SFRS1 interacting protein 1 0.00607053
COLEC12 collectin sub-family member 12 0.00606702
CPE carboxypeptidase E 0.00605687
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.00605166
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.00603616
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.0060314
SOS2 son of sevenless homolog 2 (Drosophila) 0.00601751
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00600031
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00598719
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00598546
ZFP36L1 ZFP36 ring finger protein-like 1 0.00597286
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.00596231
BEX4 brain expressed, X-linked 4 0.0059521
ANKRD46 ankyrin repeat domain 46 0.00594403
HMGB2 high mobility group box 2 0.00593662
EMP1 epithelial membrane protein 1 0.00593599
SRGN serglycin 0.00593358
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00592262
MANSC1 MANSC domain containing 1 0.0059138
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.00591241
KANK2 KN motif and ankyrin repeat domains 2 0.0059101
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00590344
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00589062
SNX7 sorting nexin 7 0.0058704
CXCL12 chemokine (C-X-C motif) ligand 12 0.00586614
IFI16 interferon, gamma-inducible protein 16 0.00586444
TNIK TRAF2 and NCK interacting kinase 0.005863
TTN titin 0.00585004
CD14 CD14 molecule 0.00584845
GSDMB gasdermin B 0.00584538
NEK9 NIMA-related kinase 9 0.00584437
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.00583772
CLGN calmegin 0.00583087
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00581678
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.00580132
NPTN neuroplastin 0.00579934
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.00579343
PDZD8 PDZ domain containing 8 0.00578994
SFRP1 secreted frizzled-related protein 1 0.00577912
TNPO1 transportin 1 0.00577448
FAM172A family with sequence similarity 172, member A 0.00576734
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00576606
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.00576372
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00576124
EXOC5 exocyst complex component 5 0.00575977
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00575714
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00574243
ADORA2B adenosine A2b receptor 0.00573386
GIMAP6 GTPase, IMAP family member 6 0.00572672
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00572534
PIP prolactin-induced protein 0.00571723
NCK1 NCK adaptor protein 1 0.00570938
TSEN2 TSEN2 tRNA splicing endonuclease subunit 0.00569444
EXPH5 exophilin 5 0.00568772
SOX9 SRY (sex determining region Y)-box 9 0.00568
TPD52 tumor protein D52 0.00567048
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.00566713
BTBD3 BTB (POZ) domain containing 3 0.00566441
WDFY3 WD repeat and FYVE domain containing 3 0.00565976
SST somatostatin 0.00565504
BID BH3 interacting domain death agonist 0.00564537
ALOX5 arachidonate 5-lipoxygenase 0.00564365
ARL4A ADP-ribosylation factor-like 4A 0.00564224
PKN2 protein kinase N2 0.00562604
MINPP1 multiple inositol-polyphosphate phosphatase 1 0.00562391
MGAM maltase-glucoamylase 0.00561414
IFI44 interferon-induced protein 44 0.00560232
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00559999
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 0.00559963
COL6A3 collagen, type VI, alpha 3 0.00558768
DUSP6 dual specificity phosphatase 6 0.00556926
PEG3 paternally expressed 3 0.00555301
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00555143
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.00553267
OPA1 optic atrophy 1 (autosomal dominant) 0.00553105
NLGN4X neuroligin 4, X-linked 0.00552706

decreased expression

Symbol Name Standardized Value
AKR1C2 aldo-keto reductase family 1, member C2 -0.0118887
AKR1C1 aldo-keto reductase family 1, member C1 -0.0116925
PWP1 PWP1 homolog (S. cerevisiae) -0.0115496
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0108761
CRIP1 cysteine-rich protein 1 (intestinal) -0.010334
KRT7 keratin 7, type II -0.0102853
AKR1C3 aldo-keto reductase family 1, member C3 -0.0102073
MAL mal, T-cell differentiation protein -0.0100385
BAMBI BMP and activin membrane-bound inhibitor -0.00962805
NNMT nicotinamide N-methyltransferase -0.00953062
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 -0.0090121
AQP3 aquaporin 3 (Gill blood group) -0.00892848
SCAND1 SCAN domain containing 1 -0.00886499
THBS2 thrombospondin 2 -0.00875406
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00839817
PEBP1 phosphatidylethanolamine binding protein 1 -0.0083883
TXNDC9 thioredoxin domain containing 9 -0.00814568
NDRG1 N-myc downstream regulated 1 -0.00812957
FXYD2 FXYD domain containing ion transport regulator 2 -0.00812022
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -0.00804834
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00795531
BGN biglycan -0.00778846
KYNU kynureninase -0.00759024
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 -0.00753943
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa -0.0075188
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00741475
GLYAT glycine-N-acyltransferase -0.00741191
SLPI secretory leukocyte peptidase inhibitor -0.00738654
SDC4 syndecan 4 -0.00726165
EFNA1 ephrin-A1 -0.00724019
TALDO1 transaldolase 1 -0.00721727
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00721284
TRAF4 TNF receptor-associated factor 4 -0.00721095
SSR4 signal sequence receptor, delta -0.00720547
PKM pyruvate kinase, muscle -0.00718233
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00710242
UBE2S ubiquitin-conjugating enzyme E2S -0.00709871
ECM1 extracellular matrix protein 1 -0.00707489
CSTB cystatin B (stefin B) -0.0070337
GSTP1 glutathione S-transferase pi 1 -0.00701431
CARHSP1 calcium regulated heat stable protein 1, 24kDa -0.00701203
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00700701
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.00700447
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -0.00697748
RALY RALY heterogeneous nuclear ribonucleoprotein -0.00696855
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00686324
TEX10 testis expressed 10 -0.00686084
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00682466
LBH limb bud and heart development -0.00681518
GFUS GDP-L-fucose synthase -0.0067305
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -0.00670596
MEF2C myocyte enhancer factor 2C -0.00668986
MALT1 MALT1 paracaspase -0.00662982
DMTF1 cyclin D binding myb-like transcription factor 1 -0.00661932
OGDHL oxoglutarate dehydrogenase-like -0.00656096
CD9 CD9 molecule -0.00650147
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.00647016
MT1F metallothionein 1F -0.00646935
MZT2A mitotic spindle organizing protein 2A -0.00644163
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -0.00642887
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00642433
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00639589
HSPB1 heat shock 27kDa protein 1 -0.0063912
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -0.0063469
R3HDM4 R3H domain containing 4 -0.0062937
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -0.00625839
PLK1 polo-like kinase 1 -0.00625344
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00624065
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -0.0062396
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -0.00623713
GMDS GDP-mannose 4,6-dehydratase -0.00623075
S100A11 S100 calcium binding protein A11 -0.00620873
GLDC glycine dehydrogenase (decarboxylating) -0.00618303
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00617791
EPS8L2 EPS8-like 2 -0.00617295
KRT17 keratin 17, type I -0.00616039
MT1G metallothionein 1G -0.00615939
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -0.00614757
BHMT betaine--homocysteine S-methyltransferase -0.00614601
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -0.00612574
RGS13 regulator of G-protein signaling 13 -0.00608392
MT1H metallothionein 1H -0.00607103
CST3 cystatin C -0.00606818
HOXC6 homeobox C6 -0.00606432
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00605887
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -0.00605834
GLA galactosidase, alpha -0.00605441
FOLR1 folate receptor 1 (adult) -0.00603907
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 -0.0060375
SLC25A46 solute carrier family 25, member 46 -0.00601293
MT1HL1 metallothionein 1H-like 1 -0.00600835
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 -0.00599918
PYGB phosphorylase, glycogen; brain -0.00599631
ZGPAT zinc finger, CCCH-type with G patch domain -0.00599506
CPNE1 copine I -0.00598584
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.0059526
HYAL1 hyaluronoglucosaminidase 1 -0.00593056
TFF1 trefoil factor 1 -0.00591451
CXADR coxsackie virus and adenovirus receptor -0.00591224
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00589951
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -0.00589116
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00587911
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.00583858
ERP29 endoplasmic reticulum protein 29 -0.00583749
DYNLL1 dynein, light chain, LC8-type 1 -0.00581741
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -0.00581195
LRP4 low density lipoprotein receptor-related protein 4 -0.00580997
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00579162
COPE coatomer protein complex, subunit epsilon -0.00579009
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00577374
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00575462
ODC1 ornithine decarboxylase 1 -0.00575366
GPI glucose-6-phosphate isomerase -0.00574559
RPL36 ribosomal protein L36 -0.0057369
CRLF1 cytokine receptor-like factor 1 -0.00572872
NEU1 sialidase 1 (lysosomal sialidase) -0.00572604
APOL1 apolipoprotein L, 1 -0.00571987
ICA1 islet cell autoantigen 1, 69kDa -0.00571273
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00570421
ISOC2 isochorismatase domain containing 2 -0.0057017
AIP aryl hydrocarbon receptor interacting protein -0.00569439
OFD1 oral-facial-digital syndrome 1 -0.0056942
SF3A2 splicing factor 3a, subunit 2, 66kDa -0.00568861
RBM42 RNA binding motif protein 42 -0.00568834
C9ORF16 chromosome 9 open reading frame 16 -0.00567415
SDF2L1 stromal cell-derived factor 2-like 1 -0.00566301
NARF nuclear prelamin A recognition factor -0.00563167
SLC25A38 solute carrier family 25, member 38 -0.00562703
RPP40 ribonuclease P/MRP 40kDa subunit -0.00559759
PA2G4 proliferation-associated 2G4, 38kDa -0.00558645
HMOX1 heme oxygenase 1 -0.00558417
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00557077
ILK integrin-linked kinase -0.00556855
ALDOA aldolase A, fructose-bisphosphate -0.0055587
CD151 CD151 molecule (Raph blood group) -0.00555487
TBCB tubulin folding cofactor B -0.00555283
PLIN3 perilipin 3 -0.00554688
RRBP1 ribosome binding protein 1 -0.00552905
COL18A1 collagen, type XVIII, alpha 1 -0.00552672
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -0.00552041
BRMS1 breast cancer metastasis suppressor 1 -0.00548442
TMEM160 transmembrane protein 160 -0.00546912
ATP5F1D ATP synthase F1 subunit delta -0.00546262
TSPAN1 tetraspanin 1 -0.00543038
GPX4 glutathione peroxidase 4 -0.00542844
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -0.00540513
TFPI2 tissue factor pathway inhibitor 2 -0.00540255
MAP1S microtubule-associated protein 1S -0.00539662
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -0.00539394
CGA glycoprotein hormones, alpha polypeptide -0.00537593
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -0.00536654
CLDN10 claudin 10 -0.00536065
TNIP1 TNFAIP3 interacting protein 1 -0.0053555
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -0.00535194
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00534918
PXDC1 PX domain containing 1 -0.00534051
HOPX HOP homeobox -0.00533802
NVL nuclear VCP-like -0.00533685
DNASE1L3 deoxyribonuclease I-like 3 -0.00532981
NAGK N-acetylglucosamine kinase -0.00531498
QPCT glutaminyl-peptide cyclotransferase -0.00530701
CNPPD1 cyclin Pas1/PHO80 domain containing 1 -0.00528389
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.00528352
KLRK1 killer cell lectin-like receptor subfamily K, member 1 -0.00527785
CBR3 carbonyl reductase 3 -0.00526458
AHCY adenosylhomocysteinase -0.00526392
NPY1R neuropeptide Y receptor Y1 -0.00526044
KRT18 keratin 18, type I -0.00525255
EIF5B eukaryotic translation initiation factor 5B -0.00525232
C21ORF91 chromosome 21 open reading frame 91 -0.00523676
NAP1L4 nucleosome assembly protein 1-like 4 -0.0052365
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.0052342
NRXN2 neurexin 2 -0.00523259
ERGIC3 ERGIC and golgi 3 -0.00523095
RPS27L ribosomal protein S27-like -0.00523084
CLEC2B C-type lectin domain family 2, member B -0.00522026
KIF3B kinesin family member 3B -0.00521997
FURIN furin (paired basic amino acid cleaving enzyme) -0.00521724
CTSD cathepsin D -0.00521662
POU2AF1 POU class 2 associating factor 1 -0.00520858
NR2F6 nuclear receptor subfamily 2, group F, member 6 -0.00520759
TUFT1 tuftelin 1 -0.00516489
LCAT lecithin-cholesterol acyltransferase -0.00515269
SEC61B Sec61 beta subunit -0.00515183
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00513982
MRPL17 mitochondrial ribosomal protein L17 -0.00513431
SALL1 spalt-like transcription factor 1 -0.00511757
TPI1 triosephosphate isomerase 1 -0.00509881
BLNK B-cell linker -0.00509368
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.00508237
LAGE3 L antigen family, member 3 -0.00507786
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -0.005077
MYDGF myeloid-derived growth factor -0.005074
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -0.00506226
UBA1 ubiquitin-like modifier activating enzyme 1 -0.00504809
GSTT1 glutathione S-transferase theta 1 -0.00504359
MRPL57 mitochondrial ribosomal protein L57 -0.0050408
MXD4 MAX dimerization protein 4 -0.00503991
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.00502671
FASTKD1 FAST kinase domains 1 -0.00501968
MRPS12 mitochondrial ribosomal protein S12 -0.00501742
CLIC3 chloride intracellular channel 3 -0.00500777
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -0.00499961
SBNO2 strawberry notch homolog 2 (Drosophila) -0.00499619
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -0.00499361
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -0.00499278
TKTL1 transketolase-like 1 -0.00498677
HRAS Harvey rat sarcoma viral oncogene homolog -0.00498126
PTH1R parathyroid hormone 1 receptor -0.00497914
ESR1 estrogen receptor 1 -0.00497489
SPIB Spi-B transcription factor (Spi-1/PU.1 related) -0.00496609
CLTB clathrin, light chain B -0.0049634
IRF7 interferon regulatory factor 7 -0.0049611
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00492143
NSFL1C NSFL1 (p97) cofactor (p47) -0.00491033
UPK1B uroplakin 1B -0.00490111
TMEM214 transmembrane protein 214 -0.00489262
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -0.00486859
SRPRB signal recognition particle receptor, B subunit -0.0048661
MRPL23 mitochondrial ribosomal protein L23 -0.00486335
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -0.00486328
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -0.00486065
ACTN4 actinin, alpha 4 -0.00485546
ZNRD2 zinc ribbon domain containing 2 -0.00485461
RETREG1 reticulophagy regulator 1 -0.00484826
RABAC1 Rab acceptor 1 (prenylated) -0.00484748
ETNPPL ethanolamine-phosphate phospho-lyase -0.00484423
EAF2 ELL associated factor 2 -0.00484132
ZBED2 zinc finger, BED-type containing 2 -0.00483896
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) -0.00482714
EIF4A3 eukaryotic translation initiation factor 4A3 -0.00479253
RPS5 ribosomal protein S5 -0.00478918
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa -0.00478891
NANS N-acetylneuraminic acid synthase -0.00478439
C19ORF24 chromosome 19 open reading frame 24 -0.0047791
MRPL28 mitochondrial ribosomal protein L28 -0.00477756
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.00477114
PLAAT3 phospholipase A and acyltransferase 3 -0.00476911
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.0047629
DOHH deoxyhypusine hydroxylase/monooxygenase -0.00475077
EEF2 eukaryotic translation elongation factor 2 -0.00473997
U2AF1 U2 small nuclear RNA auxiliary factor 1 -0.00473664
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00472793
PLA2G2D phospholipase A2, group IID -0.00472318
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor -0.00472313
PPAP2A phosphatidic acid phosphatase type 2A -0.00472175
SORD sorbitol dehydrogenase -0.00472174
BMP6 bone morphogenetic protein 6 -0.00471332
SOD1 superoxide dismutase 1, soluble -0.00471003
TMED9 transmembrane emp24 protein transport domain containing 9 -0.00470997