| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | interleukin-1 receptor-associated kinase 3|This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 11213) |
| External Link | https://ncbi.nlm.nih.gov/gene/11213 |
| Similar Terms | |
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497 genes differentially expressed following the IRAK3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI6 | interferon, alpha-inducible protein 6 | 0.0176877 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0159401 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0158355 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0133404 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0126321 |
| AGR2 | anterior gradient 2 | 0.0125584 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0123733 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0119035 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0117748 |
| S100P | S100 calcium binding protein P | 0.0117492 |
| ATF3 | activating transcription factor 3 | 0.01157 |
| IFI44 | interferon-induced protein 44 | 0.0115318 |
| IRF7 | interferon regulatory factor 7 | 0.0115247 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.0114256 |
| HMOX1 | heme oxygenase 1 | 0.0114038 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.011333 |
| TSPAN8 | tetraspanin 8 | 0.0110254 |
| MX1 | MX dynamin-like GTPase 1 | 0.0109868 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0109724 |
| QPRT | quinolinate phosphoribosyltransferase | 0.0108467 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0108136 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0107849 |
| OLFM4 | olfactomedin 4 | 0.0104865 |
| LTF | lactotransferrin | 0.0104151 |
| PIP | prolactin-induced protein | 0.0103936 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0102414 |
| SCAND1 | SCAN domain containing 1 | 0.0102362 |
| AREG | amphiregulin | 0.00968628 |
| CFD | complement factor D (adipsin) | 0.00966475 |
| IFI44L | interferon-induced protein 44-like | 0.00963239 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00944154 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00944111 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0093545 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00933875 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00930709 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00922266 |
| PCNA | proliferating cell nuclear antigen | 0.00917514 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00905029 |
| REG1A | regenerating islet-derived 1 alpha | 0.00899951 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00887968 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00872222 |
| RPS27L | ribosomal protein S27-like | 0.00871998 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00863266 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00853853 |
| APOD | apolipoprotein D | 0.00852156 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00849769 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00846367 |
| TOB1 | transducer of ERBB2, 1 | 0.00845958 |
| INAVA | innate immunity activator | 0.00844801 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00842649 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00841792 |
| RAB32 | RAB32, member RAS oncogene family | 0.00841312 |
| NXN | nucleoredoxin | 0.00840254 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00839318 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00833432 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00831145 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00818085 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00801164 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 0.00800681 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00799507 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00798264 |
| INHBA | inhibin, beta A | 0.00794554 |
| PRSS3 | protease, serine, 3 | 0.00792244 |
| CFB | complement factor B | 0.0079069 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00782156 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00777332 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00775826 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00772225 |
| ZNF586 | zinc finger protein 586 | 0.00771618 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00770898 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00768843 |
| GALC | galactosylceramidase | 0.00768365 |
| IFI35 | interferon-induced protein 35 | 0.00766378 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.00765416 |
| JAM3 | junctional adhesion molecule 3 | 0.00764746 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00762477 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00761511 |
| LCN2 | lipocalin 2 | 0.00758711 |
| DDRGK1 | DDRGK domain containing 1 | 0.00758466 |
| PROM1 | prominin 1 | 0.00754418 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00753388 |
| MIR22HG | MIR22 host gene | 0.00750902 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00749659 |
| FST | follistatin | 0.0074833 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00747667 |
| PLIN2 | perilipin 2 | 0.00744584 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) | 0.00743521 |
| PFDN4 | prefoldin subunit 4 | 0.007426 |
| SP110 | SP110 nuclear body protein | 0.00741277 |
| TFF1 | trefoil factor 1 | 0.00741093 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00740568 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00736571 |
| DCN | decorin | 0.00729589 |
| CHMP4A | charged multivesicular body protein 4A | 0.00728676 |
| GRN | granulin | 0.0072614 |
| NRBF2 | nuclear receptor binding factor 2 | 0.00723111 |
| CTSG | cathepsin G | 0.00719762 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00719411 |
| ELANE | elastase, neutrophil expressed | 0.00717646 |
| FLNA | filamin A, alpha | 0.00717058 |
| VEGFC | vascular endothelial growth factor C | 0.00716918 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00714441 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00713832 |
| IL7R | interleukin 7 receptor | 0.0070556 |
| GAS6 | growth arrest-specific 6 | 0.00704563 |
| C21ORF91 | chromosome 21 open reading frame 91 | 0.00704314 |
| GUK1 | guanylate kinase 1 | 0.00701022 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00699779 |
| ITM2A | integral membrane protein 2A | 0.00697784 |
| EGR1 | early growth response 1 | 0.00695873 |
| RRAD | Ras-related associated with diabetes | 0.00693774 |
| RPL36 | ribosomal protein L36 | 0.0069197 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.0068823 |
| FAM50A | family with sequence similarity 50, member A | 0.00682661 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00680891 |
| PYCARD | PYD and CARD domain containing | 0.00677896 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00675742 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00675142 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00674012 |
| RBPMS | RNA binding protein with multiple splicing | 0.00670883 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | 0.00670492 |
| TM4SF20 | transmembrane 4 L six family member 20 | 0.00668826 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00667871 |
| PERP | PERP, TP53 apoptosis effector | 0.00667845 |
| SSR4 | signal sequence receptor, delta | 0.00666734 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00666212 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00657985 |
| KRT14 | keratin 14, type I | 0.00657814 |
| CSRP1 | cysteine and glycine-rich protein 1 | 0.00657749 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00657312 |
| CXORF40A | chromosome X open reading frame 40A | 0.00655405 |
| SFN | stratifin | 0.00655029 |
| MSRB2 | methionine sulfoxide reductase B2 | 0.00652754 |
| AEBP1 | AE binding protein 1 | 0.00652241 |
| STK10 | serine/threonine kinase 10 | 0.00650395 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00647737 |
| DCT | dopachrome tautomerase | 0.0064665 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00641786 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 0.0064035 |
| ANXA3 | annexin A3 | 0.00639487 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.00637776 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00636868 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00635611 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00633543 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00631568 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00631416 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00630872 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00628386 |
| GPR137B | G protein-coupled receptor 137B | 0.00627801 |
| HIST1H2AE | histone cluster 1, H2ae | 0.00627202 |
| IER5 | immediate early response 5 | 0.00624691 |
| AMH | anti-Mullerian hormone | 0.00624594 |
| TPBG | trophoblast glycoprotein | 0.00624578 |
| ICOS | inducible T-cell co-stimulator | 0.00623613 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00623578 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00623227 |
| NOTCH2NL | notch 2 N-terminal like | 0.00623035 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00621903 |
| GPM6B | glycoprotein M6B | 0.00614103 |
| MX2 | MX dynamin-like GTPase 2 | 0.00612992 |
| POF1B | premature ovarian failure, 1B | 0.00612312 |
| OLFML3 | olfactomedin-like 3 | 0.00611356 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | 0.00609912 |
| DACH1 | dachshund family transcription factor 1 | 0.0060947 |
| UPP1 | uridine phosphorylase 1 | 0.00609161 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00608725 |
| USP3 | ubiquitin specific peptidase 3 | 0.00603509 |
| NSG1 | neuron specific gene family member 1 | 0.00603227 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.0060011 |
| GNG5 | guanine nucleotide binding protein (G protein), gamma 5 | 0.00598554 |
| SLC10A3 | solute carrier family 10, member 3 | 0.00598487 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00597813 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00597233 |
| CLGN | calmegin | 0.00596674 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 0.00594959 |
| NDUFB11 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa | 0.00594284 |
| IRF9 | interferon regulatory factor 9 | 0.00593241 |
| PLN | phospholamban | 0.00593081 |
| THBS4 | thrombospondin 4 | 0.00593005 |
| JUP | junction plakoglobin | 0.00592973 |
| MLPH | melanophilin | 0.00591437 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00589396 |
| GPX2 | glutathione peroxidase 2 | 0.00588426 |
| CHMP6 | charged multivesicular body protein 6 | 0.00587628 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | 0.0058536 |
| KLK5 | kallikrein-related peptidase 5 | 0.00584755 |
| CXORF40B | chromosome X open reading frame 40B | 0.0058442 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | 0.00584187 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.00583221 |
| THBS2 | thrombospondin 2 | 0.00582993 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00581944 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0058167 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00580098 |
| TES | testin LIM domain protein | 0.0057901 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.00578867 |
| KYNU | kynureninase | 0.0057852 |
| MYO6 | myosin VI | 0.00578022 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.0057742 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00576897 |
| CREM | cAMP responsive element modulator | 0.00575818 |
| G0S2 | G0/G1 switch 2 | 0.0057534 |
| MGAM | maltase-glucoamylase | 0.00574425 |
| CRAT | carnitine O-acetyltransferase | 0.00574313 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0057308 |
| RPL26L1 | ribosomal protein L26-like 1 | 0.00572966 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00572745 |
| PQBP1 | polyglutamine binding protein 1 | 0.00568077 |
| MITF | microphthalmia-associated transcription factor | 0.0056715 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00565937 |
| ATP5MG | ATP synthase membrane subunit g | 0.00565813 |
| GLA | galactosidase, alpha | 0.00565626 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00564864 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00564711 |
| KLK10 | kallikrein-related peptidase 10 | 0.00560374 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00560143 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 0.00559931 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00559061 |
| KRT5 | keratin 5, type II | 0.00558472 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.00558397 |
| EFNA1 | ephrin-A1 | 0.00558273 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00556442 |
| BPI | bactericidal/permeability-increasing protein | 0.0055552 |
| CDC42 | cell division cycle 42 | 0.00555461 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.00555215 |
| ADIRF | adipogenesis regulatory factor | 0.00554805 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | 0.0055432 |
| GATA6 | GATA binding protein 6 | 0.005538 |
| ZNF410 | zinc finger protein 410 | 0.00552828 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00552365 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.00550481 |
| HEPH | hephaestin | 0.00548609 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00547302 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00546516 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00545693 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | 0.00544795 |
| COMMD4 | COMM domain containing 4 | 0.0054478 |
| ERP44 | endoplasmic reticulum protein 44 | 0.00543908 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00543361 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.00541857 |
| UFD1 | ubiquitin recognition factor in ER associated degradation 1 | 0.00541825 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00539746 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 0.00539136 |
| CCND2 | cyclin D2 | 0.00538047 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00537681 |
| CALML5 | calmodulin-like 5 | 0.00537443 |
| LAMA5 | laminin, alpha 5 | 0.00537237 |
| SF3B5 | splicing factor 3b, subunit 5, 10kDa | 0.00537228 |
| MUC13 | mucin 13, cell surface associated | 0.00536954 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEPP1 | selenoprotein P, plasma, 1 | -0.0142048 |
| ENOPH1 | enolase-phosphatase 1 | -0.0120802 |
| TMEM176B | transmembrane protein 176B | -0.0114678 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.0106479 |
| BEX1 | brain expressed, X-linked 1 | -0.010386 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0101419 |
| FAM3C | family with sequence similarity 3, member C | -0.0100432 |
| SIRT3 | sirtuin 3 | -0.0100392 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00999851 |
| MMP12 | matrix metallopeptidase 12 | -0.00995793 |
| POSTN | periostin, osteoblast specific factor | -0.00958162 |
| METTL7A | methyltransferase like 7A | -0.00951411 |
| WEE1 | WEE1 G2 checkpoint kinase | -0.00939072 |
| SDC2 | syndecan 2 | -0.00935638 |
| PLS1 | plastin 1 | -0.00892183 |
| CCNA2 | cyclin A2 | -0.00888609 |
| SNX10 | sorting nexin 10 | -0.00880868 |
| ZNF395 | zinc finger protein 395 | -0.00876879 |
| DCK | deoxycytidine kinase | -0.00874405 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00865353 |
| NRN1 | neuritin 1 | -0.00851915 |
| HMGB1 | high mobility group box 1 | -0.00843495 |
| CDK14 | cyclin-dependent kinase 14 | -0.00840318 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00816897 |
| TMEM176A | transmembrane protein 176A | -0.00816023 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00813237 |
| COL4A1 | collagen, type IV, alpha 1 | -0.00810961 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.0081002 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00807062 |
| VSNL1 | visinin-like 1 | -0.00806137 |
| IPO5 | importin 5 | -0.00803423 |
| NNT | nicotinamide nucleotide transhydrogenase | -0.00791775 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.00790972 |
| TP53 | tumor protein p53 | -0.00788243 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00787843 |
| CLCN3 | chloride channel, voltage-sensitive 3 | -0.00783867 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00781887 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.00777566 |
| TNS3 | tensin 3 | -0.00772894 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.00770935 |
| MEN1 | multiple endocrine neoplasia I | -0.00770296 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00769269 |
| CPE | carboxypeptidase E | -0.00767581 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.00764049 |
| TRIB2 | tribbles pseudokinase 2 | -0.00761275 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00759741 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00759054 |
| OLFM1 | olfactomedin 1 | -0.00751317 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.00744072 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.00743768 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00741484 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00740085 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | -0.00729627 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | -0.00725375 |
| GSAP | gamma-secretase activating protein | -0.00723697 |
| HNMT | histamine N-methyltransferase | -0.00723523 |
| TCTA | T-cell leukemia translocation altered | -0.00722679 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00715608 |
| NAV2 | neuron navigator 2 | -0.00715075 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -0.00709956 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.00708402 |
| COL3A1 | collagen, type III, alpha 1 | -0.00707851 |
| LDB2 | LIM domain binding 2 | -0.0070632 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00704494 |
| RIDA | reactive intermediate imine deaminase A homolog | -0.00703731 |
| FZD5 | frizzled class receptor 5 | -0.00699323 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | -0.0069908 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00696851 |
| RAB2A | RAB2A, member RAS oncogene family | -0.00694841 |
| PXDN | peroxidasin | -0.00694265 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | -0.00691692 |
| EMP1 | epithelial membrane protein 1 | -0.00690658 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.00687191 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | -0.00685706 |
| PLPBP | pyridoxal phosphate binding protein | -0.00678754 |
| UBE2N | ubiquitin-conjugating enzyme E2N | -0.00677334 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00676997 |
| TERF2 | telomeric repeat binding factor 2 | -0.00675168 |
| ALB | albumin | -0.0067512 |
| KLHL2 | kelch-like family member 2 | -0.0067357 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00667806 |
| TPD52 | tumor protein D52 | -0.00664166 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.00663345 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00660969 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00660385 |
| TBC1D31 | TBC1 domain family, member 31 | -0.00653787 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00653272 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.00652574 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.00652003 |
| CENPE | centromere protein E, 312kDa | -0.00651137 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | -0.00650583 |
| EREG | epiregulin | -0.00647575 |
| SEH1L | SEH1-like (S. cerevisiae) | -0.00646415 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.00639088 |
| MMP9 | matrix metallopeptidase 9 | -0.00637353 |
| ANOS1 | anosmin 1 | -0.0063724 |
| C1RL | complement component 1, r subcomponent-like | -0.00636052 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00635461 |
| THY1 | Thy-1 cell surface antigen | -0.00631627 |
| BHMT | betaine--homocysteine S-methyltransferase | -0.00630243 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.00628639 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00628238 |
| PUS7 | pseudouridylate synthase 7 (putative) | -0.00627672 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00625819 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.00625412 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00624757 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00624392 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | -0.00623145 |
| RGCC | regulator of cell cycle | -0.00618304 |
| CLDN10 | claudin 10 | -0.00614768 |
| LOXL2 | lysyl oxidase-like 2 | -0.00614485 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -0.00611371 |
| ADORA2B | adenosine A2b receptor | -0.00611091 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00609355 |
| IPO7 | importin 7 | -0.00607482 |
| MREG | melanoregulin | -0.00607029 |
| RBM8A | RNA binding motif protein 8A | -0.00606978 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00605853 |
| FABP7 | fatty acid binding protein 7, brain | -0.00605767 |
| VEGFA | vascular endothelial growth factor A | -0.0060574 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00605623 |
| MYBPC1 | myosin binding protein C, slow type | -0.00603254 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00601247 |
| FAM120A | family with sequence similarity 120A | -0.00599351 |
| OPHN1 | oligophrenin 1 | -0.00599169 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.0059843 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.00597588 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | -0.00597261 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00597065 |
| XPO7 | exportin 7 | -0.0059654 |
| GLUL | glutamate-ammonia ligase | -0.00596289 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -0.00594334 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00593209 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.00593081 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.00591885 |
| ADM | adrenomedullin | -0.00591559 |
| XYLT1 | xylosyltransferase I | -0.005913 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00589608 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00588909 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0058874 |
| COL5A1 | collagen, type V, alpha 1 | -0.00587635 |
| A2M | alpha-2-macroglobulin | -0.00585586 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00584027 |
| PLPP3 | phospholipid phosphatase 3 | -0.00583483 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00582281 |
| CPQ | carboxypeptidase Q | -0.00581458 |
| SPRR3 | small proline-rich protein 3 | -0.00581218 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00580405 |
| NCK1 | NCK adaptor protein 1 | -0.00579401 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00579115 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.00578983 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00578325 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00577883 |
| USP34 | ubiquitin specific peptidase 34 | -0.00577833 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.00576551 |
| EFNB3 | ephrin-B3 | -0.00575199 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.0057518 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -0.00573066 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00571809 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.00570981 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00570645 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.00570523 |
| RIMBP2 | RIMS binding protein 2 | -0.00570018 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00569479 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00568753 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.00568502 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.005678 |
| AKAP11 | A kinase (PRKA) anchor protein 11 | -0.00566721 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.00564019 |
| MPZL2 | myelin protein zero-like 2 | -0.00563438 |
| RAB25 | RAB25, member RAS oncogene family | -0.00563328 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | -0.00563307 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 | -0.00563297 |
| COL1A2 | collagen, type I, alpha 2 | -0.00562606 |
| CBX5 | chromobox homolog 5 | -0.00562443 |
| UBL3 | ubiquitin-like 3 | -0.00562117 |
| OPA1 | optic atrophy 1 (autosomal dominant) | -0.00561977 |
| LIG1 | ligase I, DNA, ATP-dependent | -0.00561178 |
| NEBL | nebulette | -0.00560885 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00558196 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | -0.00557857 |
| BCL7A | B-cell CLL/lymphoma 7A | -0.00557459 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.00556684 |
| WSB2 | WD repeat and SOCS box containing 2 | -0.00552862 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00552662 |
| PAH | phenylalanine hydroxylase | -0.00552105 |
| PIPOX | pipecolic acid oxidase | -0.00551871 |
| RAB27A | RAB27A, member RAS oncogene family | -0.00551829 |
| DUT | deoxyuridine triphosphatase | -0.00550851 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00550536 |
| TCF4 | transcription factor 4 | -0.00549302 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00548468 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00548263 |
| TNC | tenascin C | -0.00546941 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | -0.00546028 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 | -0.00545301 |
| SCN3B | sodium channel, voltage gated, type III beta subunit | -0.00544224 |
| CA11 | carbonic anhydrase XI | -0.00543325 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0054229 |
| SYN1 | synapsin I | -0.00541804 |
| RGS13 | regulator of G-protein signaling 13 | -0.00541343 |
| EFHD1 | EF-hand domain family, member D1 | -0.00541208 |
| DAPK1 | death-associated protein kinase 1 | -0.005412 |
| PANK3 | pantothenate kinase 3 | -0.00539807 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.00539772 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00538089 |
| ABHD2 | abhydrolase domain containing 2 | -0.00537504 |
| ZNF83 | zinc finger protein 83 | -0.0053691 |
| CFI | complement factor I | -0.00536215 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.0053566 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | -0.00534739 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00534042 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | -0.00533162 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | -0.00531966 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00529851 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.00529825 |
| PCNT | pericentrin | -0.00528451 |
| NEK4 | NIMA-related kinase 4 | -0.0052745 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.00527209 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00527162 |
| GRB10 | growth factor receptor-bound protein 10 | -0.00526329 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00526324 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00526128 |
| SRI | sorcin | -0.00524734 |
| DMXL1 | Dmx-like 1 | -0.00524734 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00523532 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00522993 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00522405 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00522009 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00521473 |
| NDRG2 | NDRG family member 2 | -0.00520884 |
| RTN1 | reticulon 1 | -0.00519927 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.0051987 |
| PAX5 | paired box 5 | -0.00518557 |
| CA2 | carbonic anhydrase II | -0.00517098 |
| DOK5 | docking protein 5 | -0.00516859 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -0.00516814 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00516776 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00516104 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -0.00515738 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00515471 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.00515016 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00514764 |
| MLEC | malectin | -0.00512811 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.00512751 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0051134 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | -0.00510904 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.00509694 |
| VWF | von Willebrand factor | -0.00509196 |
