IRAK3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description interleukin-1 receptor-associated kinase 3|This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 11213)
External Link http://www.ncbi.nlm.nih.gov/gene/11213
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Genes

33 interacting proteins for IRAK3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
BTK Bruton agammaglobulinemia tyrosine kinase
CD14 CD14 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDCA5 cell division cycle associated 5
COPB1 coatomer protein complex, subunit beta 1
ECM1 extracellular matrix protein 1
FOLR1 folate receptor 1 (adult)
HOXB7 homeobox B7
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RAP interleukin 1 receptor accessory protein
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK4 interleukin-1 receptor-associated kinase 4
LDB1 LIM domain binding 1
LY96 lymphocyte antigen 96
MYD88 myeloid differentiation primary response 88
NONO non-POU domain containing, octamer-binding
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
TICAM2 toll-like receptor adaptor molecule 2
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TOLLIP toll interacting protein
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBC ubiquitin C