| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | interleukin-1 receptor-associated kinase 4|This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 51135) |
| External Link | https://ncbi.nlm.nih.gov/gene/51135 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the IRAK4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| WDR7 | WD repeat domain 7 | 0.0224877 |
| S100A8 | S100 calcium binding protein A8 | 0.0180209 |
| CA2 | carbonic anhydrase II | 0.0169594 |
| LCN2 | lipocalin 2 | 0.0153072 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.013777 |
| MYOF | myoferlin | 0.0133094 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.0132643 |
| NRCAM | neuronal cell adhesion molecule | 0.0125058 |
| ANXA3 | annexin A3 | 0.0121438 |
| COG7 | component of oligomeric golgi complex 7 | 0.0121265 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0120327 |
| CLTB | clathrin, light chain B | 0.0120093 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0118653 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.011412 |
| HTRA1 | HtrA serine peptidase 1 | 0.0113771 |
| AREG | amphiregulin | 0.0108397 |
| LOXL2 | lysyl oxidase-like 2 | 0.0107686 |
| FCGBP | Fc fragment of IgG binding protein | 0.0104752 |
| S100A9 | S100 calcium binding protein A9 | 0.0104465 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0102728 |
| TNS3 | tensin 3 | 0.0102387 |
| EHD2 | EH-domain containing 2 | 0.0102113 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0101889 |
| ACTN1 | actinin, alpha 1 | 0.0100982 |
| TSPO | translocator protein (18kDa) | 0.0100259 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0098754 |
| ZNF91 | zinc finger protein 91 | 0.00986247 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00970336 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00953336 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00932838 |
| SPATA20 | spermatogenesis associated 20 | 0.00932449 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00915485 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00912949 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00910997 |
| SRGN | serglycin | 0.00884114 |
| CA12 | carbonic anhydrase XII | 0.00883679 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.00878192 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00873359 |
| PFKL | phosphofructokinase, liver | 0.00871994 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00870824 |
| GRAMD2B | GRAM domain containing 2B | 0.00868506 |
| TCF4 | transcription factor 4 | 0.00864784 |
| TENM4 | teneurin transmembrane protein 4 | 0.00860548 |
| ZYX | zyxin | 0.00859389 |
| STC2 | stanniocalcin 2 | 0.00857141 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00855057 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00848053 |
| ELANE | elastase, neutrophil expressed | 0.00837774 |
| TARP | TCR gamma alternate reading frame protein | 0.00831292 |
| MGLL | monoglyceride lipase | 0.00827655 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00822765 |
| FOXD1 | forkhead box D1 | 0.00821085 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00819662 |
| PSCA | prostate stem cell antigen | 0.0081814 |
| CUX1 | cut-like homeobox 1 | 0.00813921 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00811395 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00810903 |
| CNTN1 | contactin 1 | 0.00808757 |
| PFKP | phosphofructokinase, platelet | 0.00808293 |
| BLNK | B-cell linker | 0.00808249 |
| MMP9 | matrix metallopeptidase 9 | 0.00804318 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00803824 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00800679 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0079584 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.0079485 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.00794517 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0079284 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00789057 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00785399 |
| AZU1 | azurocidin 1 | 0.00784145 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00781378 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0078077 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | 0.00779396 |
| NPAS2 | neuronal PAS domain protein 2 | 0.00776144 |
| NDRG1 | N-myc downstream regulated 1 | 0.00774668 |
| TFF1 | trefoil factor 1 | 0.00766159 |
| TRIM29 | tripartite motif containing 29 | 0.0076584 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 0.00763037 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00762969 |
| AMOTL2 | angiomotin like 2 | 0.00759357 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00757647 |
| EFNB2 | ephrin-B2 | 0.00756564 |
| NID2 | nidogen 2 (osteonidogen) | 0.00754216 |
| KLK11 | kallikrein-related peptidase 11 | 0.00753131 |
| CAMP | cathelicidin antimicrobial peptide | 0.00752953 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00752887 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.0075098 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0075064 |
| TUBA4A | tubulin, alpha 4a | 0.00748486 |
| MYRF | myelin regulatory factor | 0.00747515 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00744272 |
| VASH1 | vasohibin 1 | 0.00744156 |
| PXDN | peroxidasin | 0.00739921 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00739838 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | 0.00739195 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00736314 |
| MXRA7 | matrix-remodelling associated 7 | 0.00731341 |
| RUVBL2 | RuvB-like AAA ATPase 2 | 0.00730853 |
| MEIS2 | Meis homeobox 2 | 0.0072999 |
| KLK10 | kallikrein-related peptidase 10 | 0.00729537 |
| ATP13A2 | ATPase type 13A2 | 0.00726341 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0072396 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.00723932 |
| PTK2 | protein tyrosine kinase 2 | 0.00720548 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00719889 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00718536 |
| SIK1 | salt-inducible kinase 1 | 0.00717507 |
| GPX1 | glutathione peroxidase 1 | 0.00715306 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.0071523 |
| HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | 0.00714898 |
| CDR2L | cerebellar degeneration-related protein 2-like | 0.00713881 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa | 0.0071356 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.00713419 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00709764 |
| IPO13 | importin 13 | 0.00707032 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00706144 |
| MRC2 | mannose receptor, C type 2 | 0.00706076 |
| PDZD2 | PDZ domain containing 2 | 0.00705149 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0070335 |
| NOTCH1 | notch 1 | 0.00703231 |
| MVP | major vault protein | 0.00702654 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00702357 |
| TLE4 | transducin-like enhancer of split 4 | 0.00697667 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00697149 |
| WWC1 | WW and C2 domain containing 1 | 0.0069531 |
| PLBD1 | phospholipase B domain containing 1 | 0.00694908 |
| JMJD6 | jumonji domain containing 6 | 0.00694793 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00694614 |
| KIAA0930 | KIAA0930 | 0.00694189 |
| FAM107A | family with sequence similarity 107, member A | 0.00688728 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.00687427 |
| ZIC1 | Zic family member 1 | 0.00686738 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00686464 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 0.00684833 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 0.00684513 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00678165 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00674618 |
| TRIM16 | tripartite motif containing 16 | 0.00672298 |
| MINK1 | misshapen-like kinase 1 | 0.00670973 |
| SLC66A2 | solute carrier family 66 member 2 | 0.00670323 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00669843 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein | 0.0066796 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00667843 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00667085 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00665889 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00665888 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00662821 |
| TXNL1 | thioredoxin-like 1 | 0.00662495 |
| ARG1 | arginase 1 | 0.0066222 |
| C3 | complement component 3 | 0.00662199 |
| AUTS2 | autism susceptibility candidate 2 | 0.00662083 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00660001 |
| TSPAN5 | tetraspanin 5 | 0.00658874 |
| VCL | vinculin | 0.00657424 |
| FZD2 | frizzled class receptor 2 | 0.00657226 |
| GM2A | GM2 ganglioside activator | 0.00656516 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00655426 |
| RUNX1 | runt-related transcription factor 1 | 0.00654111 |
| METRN | meteorin, glial cell differentiation regulator | 0.00653845 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00652999 |
| MT1X | metallothionein 1X | 0.00652414 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.00651426 |
| FJX1 | four jointed box 1 (Drosophila) | 0.0064793 |
| GSDME | gasdermin E | 0.00647816 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00647444 |
| LAMB1 | laminin, beta 1 | 0.00647 |
| ATP9A | ATPase, class II, type 9A | 0.00646324 |
| CDA | cytidine deaminase | 0.0064459 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00644002 |
| SIRPA | signal-regulatory protein alpha | 0.00643168 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00643111 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0064245 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.00642261 |
| CST7 | cystatin F (leukocystatin) | 0.00641887 |
| LONP1 | lon peptidase 1, mitochondrial | 0.00641768 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.00640986 |
| NCDN | neurochondrin | 0.00640455 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00639324 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.00638941 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0063838 |
| SMAD7 | SMAD family member 7 | 0.00637397 |
| ZNF395 | zinc finger protein 395 | 0.00636756 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0063526 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00629378 |
| MEG3 | maternally expressed 3 (non-protein coding) | 0.00629142 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00628871 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 | 0.00628783 |
| OSBPL1A | oxysterol binding protein-like 1A | 0.00627602 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00625183 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.0062462 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.00624463 |
| CAVIN1 | caveolae associated protein 1 | 0.00622983 |
| TRRAP | transformation/transcription domain-associated protein | 0.00622239 |
| DGKZ | diacylglycerol kinase, zeta | 0.00621378 |
| PEG10 | paternally expressed 10 | 0.00621337 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00620533 |
| PRTN3 | proteinase 3 | 0.00619768 |
| TMEM164 | transmembrane protein 164 | 0.00618452 |
| BTG2 | BTG family, member 2 | 0.00618429 |
| SYT17 | synaptotagmin XVII | 0.00616622 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00616474 |
| GYS1 | glycogen synthase 1 (muscle) | 0.00615459 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00614661 |
| LAMA5 | laminin, alpha 5 | 0.00614067 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00612985 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00611998 |
| TECPR2 | tectonin beta-propeller repeat containing 2 | 0.00610265 |
| SEPTIN8 | septin 8 | 0.00610142 |
| IRF1 | interferon regulatory factor 1 | 0.00610052 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.0060969 |
| STK39 | serine threonine kinase 39 | 0.006095 |
| MAP7D1 | MAP7 domain containing 1 | 0.00608744 |
| SYNGR3 | synaptogyrin 3 | 0.0060709 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.00606901 |
| PPL | periplakin | 0.00606401 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 0.00605532 |
| ZSWIM8 | zinc finger, SWIM-type containing 8 | 0.00604728 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.00604218 |
| ITPKB | inositol-trisphosphate 3-kinase B | 0.00602591 |
| ZFHX4 | zinc finger homeobox 4 | 0.00600347 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00598696 |
| CYBB | cytochrome b-245, beta polypeptide | 0.0059681 |
| PLXNA1 | plexin A1 | 0.00596193 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00595698 |
| EPS8L1 | EPS8-like 1 | 0.0059545 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.00594192 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.00594099 |
| TUFM | Tu translation elongation factor, mitochondrial | 0.0059397 |
| SPRR3 | small proline-rich protein 3 | 0.00593432 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.00591578 |
| EGR1 | early growth response 1 | 0.0059116 |
| MLXIP | MLX interacting protein | 0.00588397 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00586729 |
| TPBG | trophoblast glycoprotein | 0.00585559 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00584631 |
| TRIM28 | tripartite motif containing 28 | 0.00583791 |
| TBC1D16 | TBC1 domain family, member 16 | 0.00583355 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.005818 |
| TCAF1 | TRPM8 channel-associated factor 1 | 0.0058154 |
| EXOC7 | exocyst complex component 7 | 0.00581119 |
| SLC46A3 | solute carrier family 46, member 3 | 0.00580315 |
| MEGF8 | multiple EGF-like-domains 8 | 0.00579853 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00579466 |
| CTSG | cathepsin G | 0.00578406 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00577703 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | 0.00577667 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 | 0.00575934 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00575718 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00575376 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00573666 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0151196 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0124278 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0121596 |
| IFI44 | interferon-induced protein 44 | -0.0121042 |
| EPCAM | epithelial cell adhesion molecule | -0.011943 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.0118415 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.0111075 |
| MCOLN1 | mucolipin 1 | -0.0108212 |
| LUM | lumican | -0.0107864 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0107205 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0105621 |
| FGF13 | fibroblast growth factor 13 | -0.0104313 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00996561 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00988494 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00982701 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00969893 |
| IFI44L | interferon-induced protein 44-like | -0.00969016 |
| FRZB | frizzled-related protein | -0.00958387 |
| DCLK1 | doublecortin-like kinase 1 | -0.00954838 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00954609 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00950676 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00945876 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00925687 |
| NVL | nuclear VCP-like | -0.00895144 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00875677 |
| BAG2 | BCL2-associated athanogene 2 | -0.00862266 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00861299 |
| STK26 | serine/threonine protein kinase 26 | -0.00857175 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00852656 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00850012 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00844917 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00838965 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00835724 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00835271 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00832782 |
| TMEM14B | transmembrane protein 14B | -0.00829116 |
| YEATS4 | YEATS domain containing 4 | -0.00824631 |
| FNDC3A | fibronectin type III domain containing 3A | -0.00817954 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00810697 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00810407 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00807985 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.00807691 |
| MGP | matrix Gla protein | -0.00797171 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00796752 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00796606 |
| KRT19 | keratin 19, type I | -0.00793808 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00792871 |
| GLOD4 | glyoxalase domain containing 4 | -0.00790778 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00788969 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00788086 |
| PON3 | paraoxonase 3 | -0.0078063 |
| TNC | tenascin C | -0.00779109 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.00775284 |
| FASTKD3 | FAST kinase domains 3 | -0.00771401 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.00760052 |
| CLDND1 | claudin domain containing 1 | -0.00755679 |
| RPA3 | replication protein A3, 14kDa | -0.0075219 |
| DAZAP2 | DAZ associated protein 2 | -0.0074758 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00745773 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00744754 |
| WIF1 | WNT inhibitory factor 1 | -0.00740824 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00740364 |
| CARTPT | CART prepropeptide | -0.00738036 |
| CTSK | cathepsin K | -0.00735809 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.0073564 |
| ESD | esterase D | -0.00732746 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00727521 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | -0.00727185 |
| OIP5 | Opa interacting protein 5 | -0.00726422 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00724229 |
| HNMT | histamine N-methyltransferase | -0.00724151 |
| MOB4 | MOB family member 4, phocein | -0.00721889 |
| KANSL2 | KAT8 regulatory NSL complex subunit 2 | -0.00720811 |
| ATG5 | autophagy related 5 | -0.00720045 |
| FZD6 | frizzled class receptor 6 | -0.00717559 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00716895 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.0071581 |
| NPY1R | neuropeptide Y receptor Y1 | -0.0071277 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00712175 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00709369 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00706743 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00703305 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00702036 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00700822 |
| CCNB1 | cyclin B1 | -0.00699294 |
| MMP7 | matrix metallopeptidase 7 | -0.00696001 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.00695931 |
| HSPE1 | heat shock 10kDa protein 1 | -0.00695287 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00693493 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00682817 |
| POSTN | periostin, osteoblast specific factor | -0.0068192 |
| RSL24D1 | ribosomal L24 domain containing 1 | -0.0067897 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00674982 |
| GCH1 | GTP cyclohydrolase 1 | -0.00673277 |
| MARCO | macrophage receptor with collagenous structure | -0.00671812 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00669237 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00667805 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.00664266 |
| PEX2 | peroxisomal biogenesis factor 2 | -0.00662472 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | -0.00660461 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | -0.00659462 |
| TSPYL5 | TSPY-like 5 | -0.00659158 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00654513 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00651567 |
| CD52 | CD52 molecule | -0.00651204 |
| FBXO5 | F-box protein 5 | -0.00650886 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00650554 |
| CHRDL1 | chordin-like 1 | -0.00650437 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.00650273 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00646019 |
| VCAN | versican | -0.00645473 |
| FABP1 | fatty acid binding protein 1, liver | -0.00643404 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00641493 |
| CD99 | CD99 molecule | -0.00638782 |
| PELO | pelota homolog (Drosophila) | -0.00637891 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.0063782 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00636133 |
| HOXD1 | homeobox D1 | -0.00635825 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00635161 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00634722 |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 | -0.00634651 |
| ILF2 | interleukin enhancer binding factor 2 | -0.00634558 |
| COCH | cochlin | -0.00632834 |
| AGA | aspartylglucosaminidase | -0.00629204 |
| HPN | hepsin | -0.00626618 |
| ACTL6A | actin-like 6A | -0.00626366 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00626229 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 | -0.00625795 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00625192 |
| SRP9 | signal recognition particle 9kDa | -0.00624995 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00624523 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00624028 |
| PTH2R | parathyroid hormone 2 receptor | -0.00620632 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00620501 |
| SELENOF | selenoprotein F | -0.0061972 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00619365 |
| GAS2 | growth arrest-specific 2 | -0.00618643 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.00616995 |
| GSTO1 | glutathione S-transferase omega 1 | -0.00614809 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00612611 |
| BCHE | butyrylcholinesterase | -0.00612354 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -0.006115 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | -0.00610635 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.00610609 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00610403 |
| CD69 | CD69 molecule | -0.00609365 |
| PARPBP | PARP1 binding protein | -0.00607633 |
| CALCRL | calcitonin receptor-like | -0.00607246 |
| MRPL42 | mitochondrial ribosomal protein L42 | -0.00606158 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00605835 |
| MX2 | MX dynamin-like GTPase 2 | -0.00601724 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | -0.00601697 |
| NDC80 | NDC80 kinetochore complex component | -0.00600649 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00599497 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00598519 |
| BTG3 | BTG family, member 3 | -0.00598501 |
| PLA1A | phospholipase A1 member A | -0.00598139 |
| PRPF4 | pre-mRNA processing factor 4 | -0.00594518 |
| TOX3 | TOX high mobility group box family member 3 | -0.00594482 |
| GTF3A | general transcription factor IIIA | -0.00594336 |
| MED21 | mediator complex subunit 21 | -0.00593828 |
| C4BPA | complement component 4 binding protein, alpha | -0.00592673 |
| CPB2 | carboxypeptidase B2 (plasma) | -0.00592156 |
| RLN2 | relaxin 2 | -0.00592138 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | -0.00590177 |
| FBXO28 | F-box protein 28 | -0.00590018 |
| OLFM1 | olfactomedin 1 | -0.00587847 |
| TAGLN2 | transgelin 2 | -0.00586072 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00584485 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00583529 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00583523 |
| THAP9-AS1 | THAP9 antisense RNA 1 | -0.00583131 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | -0.00582749 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00581011 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00579174 |
| SFTPD | surfactant protein D | -0.0057912 |
| FMO5 | flavin containing monooxygenase 5 | -0.00578985 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00578397 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00578158 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00577859 |
| ANGEL2 | angel homolog 2 (Drosophila) | -0.00576876 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | -0.00574758 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.00574098 |
| PLN | phospholamban | -0.0057299 |
| CALCA | calcitonin-related polypeptide alpha | -0.0057292 |
| CD1E | CD1e molecule | -0.00572337 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.0057152 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.00571124 |
| CDC123 | cell division cycle 123 | -0.00571016 |
| PQBP1 | polyglutamine binding protein 1 | -0.00571011 |
| COPS7A | COP9 signalosome subunit 7A | -0.00569709 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00569299 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00569161 |
| CP | ceruloplasmin (ferroxidase) | -0.00568795 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.0056804 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00567075 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.0056704 |
| RRP15 | ribosomal RNA processing 15 homolog (S. cerevisiae) | -0.00566093 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.00565212 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00565035 |
| PIP | prolactin-induced protein | -0.00564774 |
| NEK2 | NIMA-related kinase 2 | -0.00563953 |
| PON1 | paraoxonase 1 | -0.00562811 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) | -0.00562639 |
| CAPRIN1 | cell cycle associated protein 1 | -0.00561291 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00558908 |
| EMP1 | epithelial membrane protein 1 | -0.00558467 |
| FZD10 | frizzled class receptor 10 | -0.00557874 |
| TXN | thioredoxin | -0.00557608 |
| CRIP2 | cysteine-rich protein 2 | -0.00557149 |
| TTK | TTK protein kinase | -0.00556421 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00555866 |
| CD46 | CD46 molecule, complement regulatory protein | -0.00555277 |
| PRDX4 | peroxiredoxin 4 | -0.00555108 |
| MRPS18B | mitochondrial ribosomal protein S18B | -0.00553797 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00551679 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00551356 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00550163 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00549509 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 | -0.00549004 |
| MX1 | MX dynamin-like GTPase 1 | -0.00548598 |
| CCN3 | cellular communication network factor 3 | -0.00547711 |
| MAGEA12 | melanoma antigen family A12 | -0.00547285 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00546869 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00546413 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00545549 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0054444 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.00544417 |
| ASF1A | anti-silencing function 1A histone chaperone | -0.00543994 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00543792 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00543604 |
| SDC2 | syndecan 2 | -0.00543146 |
| CALML5 | calmodulin-like 5 | -0.0054114 |
| CYBRD1 | cytochrome b reductase 1 | -0.00540143 |
| CD83 | CD83 molecule | -0.00539912 |
| CHPT1 | choline phosphotransferase 1 | -0.00539551 |
| GIPC2 | GIPC PDZ domain containing family, member 2 | -0.00538913 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | -0.00538739 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00538647 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.00536073 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C | -0.00536003 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 | -0.0053564 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | -0.0053449 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00534318 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00533519 |
| RNASEH2B | ribonuclease H2, subunit B | -0.0053277 |
| EDNRB | endothelin receptor type B | -0.00532307 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.00532102 |
| MYO5C | myosin VC | -0.00531936 |
