IRE1 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description endoplasmic reticulum to nucleus signaling 1|The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2081)
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Genes

100 substrates of the kinase IRE1 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
IL2RA interleukin 2 receptor, alpha
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGAP11A Rho GTPase activating protein 11A
WNK1 WNK lysine deficient protein kinase 1
LBR lamin B receptor
ORAI1 ORAI calcium release-activated calcium modulator 1
HEXIM1 hexamethylene bis-acetamide inducible 1
MCM4 minichromosome maintenance complex component 4
LIMA1 LIM domain and actin binding 1
NCF1 neutrophil cytosolic factor 1
NCF4 neutrophil cytosolic factor 4, 40kDa
BIRC6 baculoviral IAP repeat containing 6
IRS1 insulin receptor substrate 1
IRS4 insulin receptor substrate 4
CDK13 cyclin-dependent kinase 13
PLK1 polo-like kinase 1
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
PER1 period circadian clock 1
TACC1 transforming, acidic coiled-coil containing protein 1
MKI67 marker of proliferation Ki-67
GSG2 germ cell associated 2 (haspin)
TRA2A transformer 2 alpha homolog (Drosophila)
TRA2B transformer 2 beta homolog (Drosophila)
UNC13D unc-13 homolog D (C. elegans)
DMAP1 DNA methyltransferase 1 associated protein 1
RAB11FIP3 RAB11 family interacting protein 3 (class II)
ARGLU1 arginine and glutamate rich 1
TACSTD2 tumor-associated calcium signal transducer 2
RNMT RNA (guanine-7-) methyltransferase
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
SELL selectin L
SHROOM1 shroom family member 1
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae)
LDB1 LIM domain binding 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
PTGDR2 prostaglandin D2 receptor 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
AKAP5 A kinase (PRKA) anchor protein 5
PKP2 plakophilin 2
TOR4A torsin family 4, member A
RBM12 RNA binding motif protein 12
RBBP6 retinoblastoma binding protein 6
SRSF4 serine/arginine-rich splicing factor 4
SRSF7 serine/arginine-rich splicing factor 7
SRSF1 serine/arginine-rich splicing factor 1
SRSF3 serine/arginine-rich splicing factor 3
SRSF2 serine/arginine-rich splicing factor 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
HPSE heparanase
KDM1A lysine (K)-specific demethylase 1A
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
PRM1 protamine 1
PRM2 protamine 2
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
FHDC1 FH2 domain containing 1
AHR aryl hydrocarbon receptor
NOP2 NOP2 nucleolar protein
SRRM2 serine/arginine repetitive matrix 2
ARHGAP21 Rho GTPase activating protein 21
PKD2 polycystic kidney disease 2 (autosomal dominant)
DRD2 dopamine receptor D2
PHF2 PHD finger protein 2
CHERP calcium homeostasis endoplasmic reticulum protein
ADRA2A adrenoceptor alpha 2A
PGBD3 piggyBac transposable element derived 3
CYTH2 cytohesin 2
FXR2 fragile X mental retardation, autosomal homolog 2
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
SRSF10 serine/arginine-rich splicing factor 10
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
CDCA2 cell division cycle associated 2
ZCCHC17 zinc finger, CCHC domain containing 17
DSP desmoplakin
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
LMNA lamin A/C
CASR calcium-sensing receptor
PPP1R12C protein phosphatase 1, regulatory subunit 12C
KCNK12 potassium channel, two pore domain subfamily K, member 12
TCF3 transcription factor 3
FXYD1 FXYD domain containing ion transport regulator 1
TWIST1 twist family bHLH transcription factor 1
TP53 tumor protein p53
C1ORF35 chromosome 1 open reading frame 35
DGKD diacylglycerol kinase, delta 130kDa
SPAG9 sperm associated antigen 9
HMGB1 high mobility group box 1
CDC25A cell division cycle 25A
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
H2AFX H2A histone family, member X
HSPB8 heat shock 22kDa protein 8
INCENP inner centromere protein antigens 135/155kDa
IFI16 interferon, gamma-inducible protein 16
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
NIFK nucleolar protein interacting with the FHA domain of MKI67
SF1 splicing factor 1
NOP58 NOP58 ribonucleoprotein
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
PUM1 pumilio RNA-binding family member 1
CHD1 chromodomain helicase DNA binding protein 1