IRF Gene Set

Dataset	MotifMap Predicted Transcription Factor Targets
Category	genomics
Type	transcription factor
Description	tripartite motif containing 63, E3 ubiquitin protein ligase\|This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012] (NCBI Entrez Gene Database, 84676)
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Genes

12 target genes of the IRF transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol	Name
ARHGAP30	Rho GTPase activating protein 30
B2M	beta-2-microglobulin
CRTC2	CREB regulated transcription coactivator 2
GRK6	G protein-coupled receptor kinase 6
IFIT2	interferon-induced protein with tetratricopeptide repeats 2
IFNB1	interferon, beta 1, fibroblast
KAT2A	K(lysine) acetyltransferase 2A
LMO7	LIM domain 7
LY86	lymphocyte antigen 86
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
USP42	ubiquitin specific peptidase 42
ZBTB44	zinc finger and BTB domain containing 44