IRF1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description interferon regulatory factor 1|IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3659)
External Link https://ncbi.nlm.nih.gov/gene/3659
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Genes

499 genes differentially expressed following the IRF1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
FABP4 fatty acid binding protein 4, adipocyte 0.0170419
ACAT2 acetyl-CoA acetyltransferase 2 0.0156745
MGP matrix Gla protein 0.0143611
MOXD1 monooxygenase, DBH-like 1 0.014329
FHL1 four and a half LIM domains 1 0.01368
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.0136197
MYBPC1 myosin binding protein C, slow type 0.0131083
RGCC regulator of cell cycle 0.0129871
FABP7 fatty acid binding protein 7, brain 0.012127
PUF60 poly-U binding splicing factor 60KDa 0.0117356
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0112312
PTCH1 patched 1 0.0108585
EMP2 epithelial membrane protein 2 0.0105057
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.0102685
NRN1 neuritin 1 0.0102493
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.0102233
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0102124
GPC3 glypican 3 0.0101733
ASCL1 achaete-scute family bHLH transcription factor 1 0.0101095
BEX1 brain expressed, X-linked 1 0.0101063
CXCL12 chemokine (C-X-C motif) ligand 12 0.0100596
OPHN1 oligophrenin 1 0.00993462
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0098348
PDE4B phosphodiesterase 4B, cAMP-specific 0.00983382
TNNC1 troponin C type 1 (slow) 0.00983032
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00982476
SRPX sushi-repeat containing protein, X-linked 0.00977196
SORBS1 sorbin and SH3 domain containing 1 0.00974207
WIF1 WNT inhibitory factor 1 0.0095872
LRP4 low density lipoprotein receptor-related protein 4 0.00952344
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00945268
NES nestin 0.00943514
LY6D lymphocyte antigen 6 complex, locus D 0.00924339
ELOVL2 ELOVL fatty acid elongase 2 0.0092348
S100P S100 calcium binding protein P 0.0091808
TUBB2B tubulin, beta 2B class IIb 0.00913981
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00910738
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.00909669
SRPX2 sushi-repeat containing protein, X-linked 2 0.00905935
TSPYL5 TSPY-like 5 0.00891071
DMTF1 cyclin D binding myb-like transcription factor 1 0.00887895
BHLHE41 basic helix-loop-helix family, member e41 0.00875082
A2M alpha-2-macroglobulin 0.00870797
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00868415
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00867185
SPRR3 small proline-rich protein 3 0.00862628
OGN osteoglycin 0.00859108
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00857863
TACSTD2 tumor-associated calcium signal transducer 2 0.00833793
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00833322
RELN reelin 0.00826136
BMP7 bone morphogenetic protein 7 0.00825274
CES1 carboxylesterase 1 0.00825228
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00822231
GPM6B glycoprotein M6B 0.00821153
TYRP1 tyrosinase-related protein 1 0.00818621
ALB albumin 0.00816689
THBS4 thrombospondin 4 0.00813023
SPRED2 sprouty-related, EVH1 domain containing 2 0.00800664
C14ORF132 chromosome 14 open reading frame 132 0.00794494
RBM39 RNA binding motif protein 39 0.00788714
TP63 tumor protein p63 0.00788369
BMP4 bone morphogenetic protein 4 0.00788239
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.0078338
MAL mal, T-cell differentiation protein 0.0078076
FMO2 flavin containing monooxygenase 2 (non-functional) 0.00779941
SOX11 SRY (sex determining region Y)-box 11 0.00777513
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00773247
PTHLH parathyroid hormone-like hormone 0.00768922
MME membrane metallo-endopeptidase 0.00767987
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00767289
ORM1 orosomucoid 1 0.00760084
RNASET2 ribonuclease T2 0.00758218
KRT15 keratin 15, type I 0.0075718
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00756532
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.00754569
AKAP12 A kinase (PRKA) anchor protein 12 0.00750883
ANXA1 annexin A1 0.00746993
ZFP36L2 ZFP36 ring finger protein-like 2 0.00742609
PMP2 peripheral myelin protein 2 0.00742421
SYNM synemin, intermediate filament protein 0.00738496
RFTN1 raftlin, lipid raft linker 1 0.00731105
AZIN1 antizyme inhibitor 1 0.00729878
KRT13 keratin 13, type I 0.00728812
BGN biglycan 0.00728041
FGF1 fibroblast growth factor 1 (acidic) 0.00724665
MREG melanoregulin 0.00722218
FOXG1 forkhead box G1 0.00722005
NEBL nebulette 0.00721652
PLP1 proteolipid protein 1 0.00720874
SCD5 stearoyl-CoA desaturase 5 0.00717324
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00715665
PLLP plasmolipin 0.00711077
SPINK5 serine peptidase inhibitor, Kazal type 5 0.0070875
CSRP2 cysteine and glycine-rich protein 2 0.00706484
TSPAN8 tetraspanin 8 0.00698648
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00698592
ALCAM activated leukocyte cell adhesion molecule 0.00696297
IFNGR1 interferon gamma receptor 1 0.00694386
CDC42 cell division cycle 42 0.00694024
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00691994
PTN pleiotrophin 0.00689635
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00688475
CD9 CD9 molecule 0.00688272
LOXL1 lysyl oxidase-like 1 0.0068603
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.00684722
PCDH9 protocadherin 9 0.0068456
EHD3 EH-domain containing 3 0.00682156
TMEM100 transmembrane protein 100 0.00680542
DMD dystrophin 0.00680415
ZNF423 zinc finger protein 423 0.00679572
ARG2 arginase 2 0.0067876
THBS2 thrombospondin 2 0.00678573
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.0067744
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00676831
ANOS1 anosmin 1 0.00674673
GPM6A glycoprotein M6A 0.0067364
G0S2 G0/G1 switch 2 0.00672719
KRT19 keratin 19, type I 0.00668535
CALCRL calcitonin receptor-like 0.00667906
MSMB microseminoprotein, beta- 0.00667678
ABLIM1 actin binding LIM protein 1 0.00665535
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00663333
FAR2 fatty acyl CoA reductase 2 0.00663277
SALL2 spalt-like transcription factor 2 0.00661434
WASF2 WAS protein family, member 2 0.0066136
MLF1 myeloid leukemia factor 1 0.00660739
CNIH3 cornichon family AMPA receptor auxiliary protein 3 0.00660028
WWTR1 WW domain containing transcription regulator 1 0.00659199
DLK1 delta-like 1 homolog (Drosophila) 0.0065822
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00657829
CEMIP cell migration inducing protein, hyaluronan binding 0.00656906
IL17RB interleukin 17 receptor B 0.0065596
OLFM1 olfactomedin 1 0.0065569
ZSCAN18 zinc finger and SCAN domain containing 18 0.00654452
ELN elastin 0.00653523
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.0065283
LAMA2 laminin, alpha 2 0.00652824
AREG amphiregulin 0.00651862
GYPC glycophorin C (Gerbich blood group) 0.00649107
PAMR1 peptidase domain containing associated with muscle regeneration 1 0.00648598
UST uronyl-2-sulfotransferase 0.00648107
FCGBP Fc fragment of IgG binding protein 0.00647772
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00647508
ANXA11 annexin A11 0.00644233
SFRP1 secreted frizzled-related protein 1 0.00644002
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.00643487
SIRT3 sirtuin 3 0.00641738
CADPS2 Ca++-dependent secretion activator 2 0.00640833
FHOD3 formin homology 2 domain containing 3 0.00640537
PRKCA protein kinase C, alpha 0.00639905
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00639658
TMEM243 transmembrane protein 243, mitochondrial 0.00639371
MAOA monoamine oxidase A 0.00638671
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00635226
TTN titin 0.00634688
AQP1 aquaporin 1 (Colton blood group) 0.00634305
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00633962
EMP1 epithelial membrane protein 1 0.0063351
PSAT1 phosphoserine aminotransferase 1 0.00632503
SET SET nuclear proto-oncogene 0.00631836
MAOB monoamine oxidase B 0.00631705
CDO1 cysteine dioxygenase type 1 0.00630172
GNAS GNAS complex locus 0.00629949
F3 coagulation factor III (thromboplastin, tissue factor) 0.00628585
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00625815
DOK5 docking protein 5 0.00624656
ADGRG2 adhesion G protein-coupled receptor G2 0.00624278
CHD7 chromodomain helicase DNA binding protein 7 0.00623327
CLCA4 chloride channel accessory 4 0.00623186
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.00623006
TMEM255A transmembrane protein 255A 0.00622969
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 0.00622946
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00620618
NFASC neurofascin 0.00619546
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.00617712
LYZ lysozyme 0.00615601
ZNF185 zinc finger protein 185 (LIM domain) 0.00613357
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00613096
FGG fibrinogen gamma chain 0.00609725
FXYD5 FXYD domain containing ion transport regulator 5 0.00609082
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.00606171
TNS1 tensin 1 0.00602549
EDN3 endothelin 3 0.00601265
TRIM9 tripartite motif containing 9 0.00600853
MYOZ2 myozenin 2 0.00597541
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.00594467
TACC2 transforming, acidic coiled-coil containing protein 2 0.0059295
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.00592753
ADGRL2 adhesion G protein-coupled receptor L2 0.00592421
GPX7 glutathione peroxidase 7 0.00591128
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.0059056
HOPX HOP homeobox 0.00590178
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00589192
WEE1 WEE1 G2 checkpoint kinase 0.00588863
TCP1 t-complex 1 0.00588123
ADIRF adipogenesis regulatory factor 0.00586974
MEF2C myocyte enhancer factor 2C 0.00585817
ASPH aspartate beta-hydroxylase 0.00584868
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.00584599
MFAP4 microfibrillar-associated protein 4 0.00582649
RADX RPA1 related single stranded DNA binding protein, X-linked 0.00581257
SELE selectin E 0.00579631
CD302 CD302 molecule 0.00578989
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00578871
COQ8A coenzyme Q8A 0.00578306
TMEM45A transmembrane protein 45A 0.00577384
ERGIC3 ERGIC and golgi 3 0.00575072
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.00572742
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00572021
ELANE elastase, neutrophil expressed 0.00571629
NASP nuclear autoantigenic sperm protein (histone-binding) 0.00567849
S100B S100 calcium binding protein B 0.00566826
TFDP1 transcription factor Dp-1 0.00566217
PER1 period circadian clock 1 0.00565228
ALOX15B arachidonate 15-lipoxygenase, type B 0.0056327
FGFR1 fibroblast growth factor receptor 1 0.00562287
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.00562261
HOMER1 homer scaffolding protein 1 0.00561848
FERMT1 fermitin family member 1 0.00561581
PADI2 peptidyl arginine deiminase, type II 0.00560605
CAVIN2 caveolae associated protein 2 0.00559268
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.00558734
PDE8B phosphodiesterase 8B 0.00558355
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00558069
COL9A3 collagen, type IX, alpha 3 0.00554414
UBXN7 UBX domain protein 7 0.00554234
TUBB2A tubulin, beta 2A class IIa 0.00553957
AK1 adenylate kinase 1 0.00553011
TDRD12 tudor domain containing 12 0.00552291
MATR3 matrin 3 0.00551787
MAGEH1 melanoma antigen family H1 0.00551374
SPARCL1 SPARC-like 1 (hevin) 0.00550474
STEAP3 STEAP family member 3, metalloreductase 0.00548485
CD200 CD200 molecule 0.00548072
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 0.00547941
MPO myeloperoxidase 0.00547356
CHIT1 chitinase 1 (chitotriosidase) 0.00547283
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00547176
POSTN periostin, osteoblast specific factor 0.00545507
LHFP lipoma HMGIC fusion partner 0.00544899
IFRD2 interferon-related developmental regulator 2 0.00544894
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.00544106
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.00543993
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00543768
GREB1 growth regulation by estrogen in breast cancer 1 0.0054362
FBLN5 fibulin 5 0.00542766
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00542662
PELI1 pellino E3 ubiquitin protein ligase 1 0.00539994
HMGA1 high mobility group AT-hook 1 0.00539578

decreased expression

Symbol Name Standardized Value
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.0197757
CXCL10 chemokine (C-X-C motif) ligand 10 -0.0179199
IFI6 interferon, alpha-inducible protein 6 -0.0159687
WDR7 WD repeat domain 7 -0.0147712
JCHAIN joining chain of multimeric IgA and IgM -0.0137036
CXCL11 chemokine (C-X-C motif) ligand 11 -0.0135338
MAP7 microtubule-associated protein 7 -0.013517
AAMDC adipogenesis associated, Mth938 domain containing -0.013478
IDO1 indoleamine 2,3-dioxygenase 1 -0.0129469
IFI44L interferon-induced protein 44-like -0.0129178
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0128535
RSAD2 radical S-adenosyl methionine domain containing 2 -0.0127785
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0126847
SSBP2 single-stranded DNA binding protein 2 -0.0117109
TSPAN4 tetraspanin 4 -0.0114817
TOX3 TOX high mobility group box family member 3 -0.0113586
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0113237
DAPK1 death-associated protein kinase 1 -0.0109575
WASHC4 WASH complex subunit 4 -0.0109108
LGALS2 lectin, galactoside-binding, soluble, 2 -0.0107013
STK26 serine/threonine protein kinase 26 -0.0107003
IL7R interleukin 7 receptor -0.0105156
TUFT1 tuftelin 1 -0.010492
PGAM1 phosphoglycerate mutase 1 (brain) -0.0104592
TYMP thymidine phosphorylase -0.0104198
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.010175
UVRAG UV radiation resistance associated -0.0101572
ISG15 ISG15 ubiquitin-like modifier -0.010136
IFI44 interferon-induced protein 44 -0.0100407
PDZK1IP1 PDZK1 interacting protein 1 -0.00976889
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00971004
SCGB1D2 secretoglobin, family 1D, member 2 -0.0095408
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00932775
ALG8 ALG8, alpha-1,3-glucosyltransferase -0.00931994
IRF7 interferon regulatory factor 7 -0.00930323
SNX11 sorting nexin 11 -0.00929494
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00925399
XAF1 XIAP associated factor 1 -0.00922169
PLXNC1 plexin C1 -0.00914002
CCL8 chemokine (C-C motif) ligand 8 -0.00911917
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00909711
SLC44A4 solute carrier family 44, member 4 -0.0090838
IFITM1 interferon induced transmembrane protein 1 -0.00907614
PLK1 polo-like kinase 1 -0.00903155
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00902738
QDPR quinoid dihydropteridine reductase -0.0089726
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00873911
RTP4 receptor (chemosensory) transporter protein 4 -0.00856802
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00852439
HNMT histamine N-methyltransferase -0.00850337
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00848871
KLF10 Kruppel-like factor 10 -0.00847813
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00839667
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00837841
TPSAB1 tryptase alpha/beta 1 -0.00834599
PLK2 polo-like kinase 2 -0.00834507
THAP12 THAP domain containing 12 -0.00830082
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00828928
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin -0.00824783
RSF1 remodeling and spacing factor 1 -0.00820674
SMAD7 SMAD family member 7 -0.00817894
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0081623
NPR3 natriuretic peptide receptor 3 -0.00811271
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0081108
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00810406
CFB complement factor B -0.00807708
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00799064
GAB2 GRB2-associated binding protein 2 -0.00793778
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.00793436
EMP3 epithelial membrane protein 3 -0.0078431
MRPS30 mitochondrial ribosomal protein S30 -0.0077656
OSBPL8 oxysterol binding protein-like 8 -0.00775673
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.00771829
WT1 Wilms tumor 1 -0.00771379
H1-2 H1.2 linker histone, cluster member -0.00767213
GBP1 guanylate binding protein 1, interferon-inducible -0.00765672
LEPROTL1 leptin receptor overlapping transcript-like 1 -0.00765053
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -0.00763516
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.0076342
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00761276
CLGN calmegin -0.00760533
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00759877
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00758974
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.00754664
RIPOR2 RHO family interacting cell polarization regulator 2 -0.00754439
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00754287
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -0.00747011
GALC galactosylceramidase -0.0073965
CLEC2B C-type lectin domain family 2, member B -0.00738647
CHN2 chimerin 2 -0.00732373
FXYD2 FXYD domain containing ion transport regulator 2 -0.00731879
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.0073026
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00729543
IFI35 interferon-induced protein 35 -0.007274
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00726933
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.007221
HIST1H2BD histone cluster 1, H2bd -0.00717182
AKR1C3 aldo-keto reductase family 1, member C3 -0.00717127
HCP5 HLA complex P5 (non-protein coding) -0.00713534
PMP22 peripheral myelin protein 22 -0.00711263
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -0.00711218
BST2 bone marrow stromal cell antigen 2 -0.00709131
POLR1D polymerase (RNA) I polypeptide D, 16kDa -0.00708945
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.007045
KLK11 kallikrein-related peptidase 11 -0.00702998
GREM1 gremlin 1, DAN family BMP antagonist -0.00696431
CYTH1 cytohesin 1 -0.00688982
CCN3 cellular communication network factor 3 -0.00688301
HIST1H2BK histone cluster 1, H2bk -0.00684988
ADAMDEC1 ADAM-like, decysin 1 -0.00684833
VEGFA vascular endothelial growth factor A -0.006836
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.006822
SOCS1 suppressor of cytokine signaling 1 -0.00680753
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.00678566
PDGFC platelet derived growth factor C -0.00678526
UPK1B uroplakin 1B -0.00675739
HDAC9 histone deacetylase 9 -0.00671717
TENT5A terminal nucleotidyltransferase 5A -0.00671674
APOL6 apolipoprotein L, 6 -0.00671226
MGAM maltase-glucoamylase -0.00671171
STX3 syntaxin 3 -0.00667399
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.00666878
SST somatostatin -0.0066596
MX2 MX dynamin-like GTPase 2 -0.00664377
BTG1 B-cell translocation gene 1, anti-proliferative -0.00663311
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00660237
RNF19B ring finger protein 19B -0.00659916
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -0.00658545
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00657046
XYLT1 xylosyltransferase I -0.00656887
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -0.00655641
ZNF91 zinc finger protein 91 -0.0065437
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -0.00653528
SCO2 SCO2 cytochrome c oxidase assembly protein -0.00652364
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00651151
KCTD14 potassium channel tetramerization domain containing 14 -0.00648296
SIDT2 SID1 transmembrane family, member 2 -0.00645023
IL18 interleukin 18 -0.00644393
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.00643623
PHACTR2 phosphatase and actin regulator 2 -0.00642209
EGR1 early growth response 1 -0.00641258
IL32 interleukin 32 -0.00639447
C1QB complement component 1, q subcomponent, B chain -0.00638262
ACTN1 actinin, alpha 1 -0.00635047
TMEM70 transmembrane protein 70 -0.00634766
PRKCB protein kinase C, beta -0.00633232
FKBP11 FK506 binding protein 11, 19 kDa -0.00633212
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00632177
ATP5MJ ATP synthase membrane subunit j -0.00631948
ARHGAP17 Rho GTPase activating protein 17 -0.00631911
TPP1 tripeptidyl peptidase I -0.00631879
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00630106
EVI2A ecotropic viral integration site 2A -0.00627031
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00627004
REG3A regenerating islet-derived 3 alpha -0.00626963
NAIP NLR family, apoptosis inhibitory protein -0.00623055
CCL5 chemokine (C-C motif) ligand 5 -0.00623025
PRAME preferentially expressed antigen in melanoma -0.00622321
NKX3-1 NK3 homeobox 1 -0.00622235
TMPRSS4 transmembrane protease, serine 4 -0.00620463
CD70 CD70 molecule -0.00619656
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00618301
HPCAL1 hippocalcin-like 1 -0.00614824
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00614374
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00609296
TMEM126B transmembrane protein 126B -0.00608287
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00605986
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.00605844
CCR1 chemokine (C-C motif) receptor 1 -0.0060308
PARP8 poly (ADP-ribose) polymerase family, member 8 -0.00600853
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -0.00598918
RNF6 ring finger protein (C3H2C3 type) 6 -0.00598719
NXF3 nuclear RNA export factor 3 -0.00598668
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -0.00598491
MYO7A myosin VIIA -0.00597543
ADCY9 adenylate cyclase 9 -0.00595133
MYRF myelin regulatory factor -0.00593935
PLAAT3 phospholipase A and acyltransferase 3 -0.00593448
SH3BP4 SH3-domain binding protein 4 -0.00592706
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00590915
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00590648
KLK5 kallikrein-related peptidase 5 -0.00588088
METRN meteorin, glial cell differentiation regulator -0.00587781
TMEM165 transmembrane protein 165 -0.00587135
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00585581
PDGFD platelet derived growth factor D -0.00584903
RRAGA Ras-related GTP binding A -0.00582703
TRIB3 tribbles pseudokinase 3 -0.00582234
DROSHA drosha, ribonuclease type III -0.00581568
GAS6 growth arrest-specific 6 -0.00581461
SSX1 synovial sarcoma, X breakpoint 1 -0.00581437
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00579551
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00579375
NCDN neurochondrin -0.00579112
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00577453
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00576076
MX1 MX dynamin-like GTPase 1 -0.00575564
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00574666
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00569872
RAB9A RAB9A, member RAS oncogene family -0.00568586
TSPAN13 tetraspanin 13 -0.00568034
FTL ferritin, light polypeptide -0.005654
MAGEB2 melanoma antigen family B2 -0.00565067
INTS6 integrator complex subunit 6 -0.00563684
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00563575
GPNMB glycoprotein (transmembrane) nmb -0.00563549
MMP1 matrix metallopeptidase 1 -0.00562591
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 -0.00561263
OASL 2'-5'-oligoadenylate synthetase-like -0.00560706
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00559869
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.00558794
PTK2B protein tyrosine kinase 2 beta -0.00558119
ADCY7 adenylate cyclase 7 -0.00553317
HIST1H2AE histone cluster 1, H2ae -0.00553061
C11ORF21 chromosome 11 open reading frame 21 -0.00552652
ELOVL5 ELOVL fatty acid elongase 5 -0.00552306
IPCEF1 interaction protein for cytohesin exchange factors 1 -0.00550664
EML3 echinoderm microtubule associated protein like 3 -0.00548218
REC8 REC8 meiotic recombination protein -0.00547805
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00544505
C1QA complement component 1, q subcomponent, A chain -0.00544419
CCR7 chemokine (C-C motif) receptor 7 -0.00543768
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.00543554
WASL Wiskott-Aldrich syndrome-like -0.00543085
CMTR1 cap methyltransferase 1 -0.00542613
CCNG2 cyclin G2 -0.00540808
MAMLD1 mastermind-like domain containing 1 -0.00540399
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -0.00540327
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -0.00539513
IFI30 interferon, gamma-inducible protein 30 -0.00539002
COMP cartilage oligomeric matrix protein -0.00538952
AFF1 AF4/FMR2 family, member 1 -0.00537026
ALOX5 arachidonate 5-lipoxygenase -0.00536532
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00536084
MLPH melanophilin -0.00535156
NRGN neurogranin (protein kinase C substrate, RC3) -0.00533664
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -0.0053279
NUSAP1 nucleolar and spindle associated protein 1 -0.00530594
RAP1GAP2 RAP1 GTPase activating protein 2 -0.00530129
TLR3 toll-like receptor 3 -0.00529817
DSE dermatan sulfate epimerase -0.00528871
REG1A regenerating islet-derived 1 alpha -0.00527173
COL11A1 collagen, type XI, alpha 1 -0.0052554
JMJD6 jumonji domain containing 6 -0.00524718
LAPTM4B lysosomal protein transmembrane 4 beta -0.00524639
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.00523252
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00522516
RESF1 retroelement silencing factor 1 -0.00521914
CXORF21 chromosome X open reading frame 21 -0.00521368